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UK science seeks ‘a new and special relationship with the EU’
Science Magazine Top science officials in United Kingdom hedge on the future relationship with European research programs 5 hours
Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques
Science Magazine The development of an effective AIDS vaccine has been challenging due to viral genetic diversity and the difficulty in generating broadly neutralizing antibodies (bnAbs). Here, we... 6 hours
U.K. pledges $88 million to gigantic U.S. particle physics experiment
Science Magazine U.K. researchers to build key parts of proposed Deep Underground Neutrino Experiment 7 hours
why flu vaccines so often fail Why flu vaccines so often fail
Science Magazine VIDEO The complex factors behind vaccine breakdowns are coming into sharper focus 9 hours
Global sea turtle conservation successes
Science Magazine We document a tendency for published estimates of population size in sea turtles to be increasing rather than decreasing across the globe. To examine the population status of the seven species of sea turtle globally, we obtained 299... 9 hours
Potyvirus virion structure shows conserved protein fold and RNA binding site in ssRNA viruses
Science Magazine Potyviruses constitute the second largest genus of plant viruses and cause important economic losses in a large variety of crops;... 9 hours
Structural analysis of BRCA1 reveals modification hotspot
Science Magazine Cancer cells afflicted with mutations in the breast cancer susceptibility protein (BRCA1) often suffer from increased DNA damage and genomic instability. The precise manner in which physical changes to BRCA1 influence its role in... 9 hours
Cryogenian evolution of stigmasteroid biosynthesis
Science Magazine Sedimentary hydrocarbon remnants of eukaryotic C26–C30 sterols can be used to reconstruct early algal evolution. Enhanced C29 sterol abundances provide algal cell membranes a density advantage in large temperature fluctuations. Here, we combined a literature review with new... 9 hours
Thresholds of catastrophe in the Earth system
Science Magazine The history of the Earth system is a story of change. Some changes are gradual and benign, but others, especially those associated with catastrophic mass extinction, are relatively abrupt and destructive. What sets one... 9 hours
Dynamics in charity donation decisions: Insights from a large longitudinal data set
Science Magazine Despite the vast body of research on charitable giving and its drivers, no research has investigated the longitudinal dynamics of individual donation decisions. We... 9 hours
Latitudinal trends in shell production cost from the tropics to the poles
Science Magazine The proportion of body mass devoted to skeleton in marine invertebrates decreases along latitudinal gradients from large proportions in the tropics to small proportions... 9 hours
Glaciation as a migratory switch
Science Magazine Migratory behavior in birds is evolutionarily plastic, but it is unclear how this behavior responded during glacial cycles. One view is that at glacial maxima, species simply shifted their breeding ranges south of glacial ice and remained migratory.... 9 hours
Intersectionality takes it to the streets: Mobilizing across diverse interests for the Womens March
Science Magazine Can a diverse crowd of individuals whose interests focus on distinct issues related to racial identity, class, gender, and sexuality... 9 hours
[Research Articles] Protection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail
Science Magazine HIV-1 sequence diversity presents a major challenge for the clinical development of broadly neutralizing antibodies (bNAbs) for both therapy and... 9 hours
[Editors' Choice] Cerebral ischemia comes in waves
Science Magazine Subarachnoid blood induces spreading depolarizations, which are associated with cortical infractions. 9 hours
[Research Articles] Responsive monitoring of mitochondrial redox states in heart muscle predicts impending cardiac arrest
Science Magazine Assessing the adequacy of oxygen delivery to tissues is vital, particularly in the fields of intensive care medicine... 9 hours
[Editors' Choice] Blocking cell death to enhance cell death
Science Magazine Inhibiting caspase activation during apoptosis may enhance the ability of the immune system to target cancer cells. 9 hours
[Research Articles] Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant
Science Magazine A critical question facing the field of transplantation is how to control... 9 hours
[Research Articles] Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice
Science Magazine Intercellular transfer of microRNAs can mediate communication between critical effector cells. We hypothesized that transfer of... 9 hours
[Focus] Single-cell analyses to tailor treatments
Science Magazine Single-cell RNA-seq could play a key role in personalized medicine by facilitating characterization of cells, pathways, and genes associated with human diseases such as cancer. 9 hours
[Editors' Choice] Learning from cancer to promote weight loss
Science Magazine Growth differentiation factor 15 suppresses appetite and promotes weight loss by activating a receptor expressed in two brain regions. 9 hours
[Editors' Choice] Education isnt everything (for infant immunity)
Science Magazine A deficit in tissue-resident memory T cell production helps explain virus susceptibility in early life. 9 hours
[Research Articles] Cancer immunotherapy with recombinant poliovirus induces IFN-dominant activation of dendritic cells and tumor antigen-specific CTLs
Science Magazine Tumors thrive in an immunosuppressive microenvironment that impedes antitumor innate and adaptive immune responses.... 9 hours
This robotic ‘remora’ can cling to objects with a force 340 times its own weight
Science Magazine VIDEO New suction disk could vastly extend the range of underwater robots 9 hours
Publishers go after networking site for illicit sharing of journal papers
Science Magazine Letter requests that ResearchGate consider removing content in violation of copyright 9 hours
Sea turtles still in peril, but many populations are climbing
Science Magazine New global analysis credits conservation efforts 9 hours
A new study is changing how scientists think about Alzheimer’s disease
Science Magazine Focus on risk gene could illuminate the illness’s origins 10 hours
Scientists use gene-editing technology to knock out genes in human embryos for first time
Science Magazine CRISPR work highlights differences in human and mouse development 10 hours
China’s atomic clock passes space test
Science Magazine Cold atom experiment operated in orbit for a year 10 hours
Scientific society defines sexual harassment as scientific misconduct
Science Magazine American Geophysical Union places harassment, bullying, and discrimination on par with falsification, fabrication, and plagiarism 11 hours
Giant trilobite crashes Wisconsin corn field
Science Magazine Science-themed corn maze will host geoscience teach-ins 12 hours
Human semen can host up to 27 different viruses
Science Magazine But how many of them are transmissible is unknown 15 hours
watch the secret to why barn owls don t lose their hearing Watch the secret to why barn owls don’t lose their hearing
Science Magazine VIDEO Scientists conduct first hearing test of its kind 1 day
Is the sky really blue? Some hunter-gatherers don’t describe colors the same way most people do
Science Magazine Findings could reveal how languages develop 2 days
Cybersecurity and technology transfer seen as top priorities for NIST director nominee
Science Magazine Walter Copan has relevant experience with federal labs and agencies 2 days
Animal hoarding is its own mental disorder, study argues
Science Magazine Researchers say the condition is distinct from typical hoarding 3 days
KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C
Science Magazine Killer cell immunoglobulin-like receptors (KIRs) are rapidly evolving species-specific natural killer (NK) cell receptors associated with protection against multiple different human viral... 5 days
Artificial intelligence just made guessing your password a whole lot easier
Science Magazine “Generative” neural networks teach themselves to guess realistic passwords 5 days
Top stories: A Viking warrior woman, PETA’s targeting of postdocs, and where spacecraft go to die
Science Magazine This week’s top Science news 5 days
Particle-hole symmetry reveals failed superconductivity in the metallic phase of two-dimensional superconducting films
Science Magazine Electrons confined to two dimensions display an unexpected diversity of behaviors as they are cooled to absolute zero. Noninteracting electrons are predicted... 5 days
Rapid and near-complete dissolution of wood lignin at
Science Magazine We report the discovery of the hydrotropic properties of a recyclable aromatic acid, p-toluenesulfonic acid (p-TsOH), for potentially low-cost and efficient fractionation of wood through rapid and near-complete dissolution of lignin. Approximately... 5 days
Bioinspired bright noniridescent photonic melanin supraballs
Science Magazine Structural colors enable the creation of a spectrum of nonfading colors without pigments, potentially replacing toxic metal oxides and conjugated organic pigments. However, significant challenges remain to achieve the contrast needed for a complete gamut of... 5 days
Assembling oppositely charged lock and key responsive colloids: A mesoscale analog of adaptive chemistry
Science Magazine We have seen a considerable effort in colloid sciences to copy Nature’s successful strategies to fabricate complex functional structures through... 5 days
Allochroic thermally activated delayed fluorescence diodes through field-induced solvatochromic effect
Science Magazine Allochroic organic light-emitting devices (AOLEDs) characterized by field-dependent emissive color variation are promising as visible signal response units for intelligent applications. Most of the AOLEDs were realized by... 5 days
Cooperative deformations of periodically patterned hydrogels
Science Magazine Nature has shown elegant paradigms of smart deformation, which inspired biomimetic systems with controllable bending, folding, and twisting that are significant for the development of soft electronics and actuators. Complex deformations are usually realized by additively... 5 days
Real-time probing of granular dynamics with magnetic resonance
Science Magazine Granular dynamics govern earthquakes, avalanches, and landslides and are of fundamental importance in a variety of industries ranging from energy to pharmaceuticals to agriculture. Nonetheless, our understanding of the underlying physics is... 5 days
CryoEM structure of MxB reveals a novel oligomerization interface critical for HIV restriction
Science Magazine Human dynamin–like, interferon-induced myxovirus resistance 2 (Mx2 or MxB) is a potent HIV-1 inhibitor. Antiviral activity requires both the amino-terminal region of... 5 days
Interplay between protein glycosylation pathways in Alzheimers disease
Science Magazine Deviations from the normal nucleoplasmic protein O-GlcNAcylation, as well as from normal protein sialylation and N-glycosylation in the secretory pathway, have been reported in Alzheimer’s disease (AD). However, the interplay between the... 5 days
new dyes that don t fade are made of the same molecule that colors your skin New dyes that don’t fade are made of the same molecule that colors your skin
Science Magazine VIDEO Structural ‘supraball’ pigments could transform cosmetics and food 5 days
Top astronomer on the challenges of building the world’s largest telescope, and what’s next
Science Magazine Xavier Barcons taking reins of the European Southern Observatory at a critical juncture 5 days
Aligning the primary mirror segments of NASA's James Webb Space Telescope with light
Mattis sees need for new space programs
This robotic ‘remora’ can cling to objects with a force 340 times its own weight
Science Magazine
Hubble discovers a unique type of object in the Solar System
Wave Glider surfs across stormy Drake Passage in Antarctica
NASA finds very heavy rainfall in Hurricane Maria
Why flu vaccines so often fail
Science Magazine
Engineers 3-D print high-strength aluminum, solve ages-old welding problem using nanoparticles
Climate change lessons from Arabian Gulf coral reefs
Space radiation is risky business for the human body
Lumbering giants had agile ancestors
Equifax breach brings renewed attention to information security vulnerabilities
Keeping astronauts – and Earth – safe from destructive solar storms
Keeping astronauts – and Earth – safe from destructive solar storms
3-D printers—a revolutionary frontier for medicine