Pharmaceuticals
Under-5's receiving an average 25 antibiotic prescriptions each year  NEWS MEDICAL · 11 hours
Antibiotic resistance is one of the greatest threats to mankind says the World Health Organization (WHO). One of the greatest contributors to this menace is indiscriminate use of antibiotics. more
Salk researchers uncover new function of mitochondria  NEWS MEDICAL · 14 hours
Mitochondria, tiny structures present in most cells, are known for their energy-generating machinery. Now, Salk researchers have discovered a new function of mitochondria: they set off molecular alarms when cells are exposed to stress... more
CSHLP releases new book on 'Metastasis: Mechanism to Therapy'  NEWS MEDICAL · 14 hours
Cold Spring Harbor Laboratory Press announced the release of Metastasis: Mechanism to Therapy, available on its website in Hardcover format. more
Medical News Today: New birth control pill provides contraception for a month  MNT · 15 hours
In pigs, researchers have developed a single birth control pill effective for 1 month. The pill could, one day, have a global impact on... more
Study unveils new layers of mystery about visual memory, amblyopia  NEWS MEDICAL · 1 day
In decades of studying how neural circuits in the brain's visual cortex adapt to experience, MIT Professor Mark Bear's lab has followed the science wherever it has led,... more
NIH provides up to $102.5 million in renewed funding for Antibacterial Resistance Leadership Group  NEWS MEDICAL · 2 days
As antibiotic-resistant bacteria become more urgent threats worldwide, the National Institute of Allergy and Infectious Diseases, part of the National... more
Brown, Insight Therapeutics partnership to accelerate research on flu vaccines for older adults  NEWS MEDICAL · 2 days
With support from a three-year $2.1 million agreement with Insight Therapeutics, a private company that focuses on the health care of older... more
Novel drug shows efficacy against advanced ROS1 and NTRK fusion-positive NSCLC  NEWS MEDICAL · 2 days
Pooled analysis of three phase 1 and 2 clinical trials published online ahead of print in the journal Lancet Oncology show that the drug entrectinib is... more
Community-based program enables donation of tumor tissue and blood samples for research  NEWS MEDICAL · 2 days
Precision medicine with targeted therapies has led to improved treatment options and patient outcomes. These approaches were developed by studying tumors grown in laboratories... more
Problem drinkers have higher likelihood of using benzodiazepines  NEWS MEDICAL · 2 days
Problem drinkers are more likely than teetotalers and moderate drinkers to take benzodiazepines, a class of sedatives that are among the most commonly prescribed drugs -- and the most abused. more
Medical News Today: At least 1 in 4 outpatient antibiotic prescriptions are 'inappropriate'  MNT · 2 days
A study of U.S. data for 2015 finds that ambulatory care providers do not document the medical reason for the drug in... more
Mitochondria are the 'canary in the coal mine' for cellular stress  SCIENCE DAILY · 2 days
Mitochondria, tiny structures present in most cells, are known for their energy-generating machinery. Now, researchers have discovered a new function of mitochondria: they set off molecular... more
Mitochondria are the 'canary in the coal mine' for cellular stress  PHYS.ORG · 2 days
Mitochondria, tiny structures present in most cells, are known for their energy-generating machinery. Now, Salk researchers have discovered a new function of mitochondria: they set off... more
How tramadol, touted as safer opioid, became 3rd world peril  ABC NEWS · 2 days
Mass abuse of the drug tramadol spans continents, from India to Africa to the Middle East. The problem is that advocates claimed it was a safer opioid, relieving... more
In surprise decision, US approves muscular dystrophy drug  ABC NEWS · 2 days
The U.S. Food and Drug Administration has approved a second drug to treat muscular dystrophy, the debilitating disease that causes loss of movement and early death more
How two experimental Alzheimer's drugs reverse aging  MNT · 2 days
New research in mice reveals the molecular and genetic mechanisms through which two Alzheimer's drug candidates can reverse aging in general. more
Finding non-invasive nuclear medicine technique to predict effectiveness of therapy for tumors  NEWS MEDICAL · 2 days
Researchers have taken a critical step toward developing a non-invasive nuclear medicine technique that can predict the effectiveness of therapy for cancerous tumors, allowing... more
Neuroscientists develop new method for uniquely targeted gene therapy  NEWS MEDICAL · 2 days
Neuroscientists at Lund University in Sweden have developed a new technology that engineers the shell of a virus to deliver gene therapy to the exact cell type in the body... more
`Safer opioid’ has sparked a crisis in vulnerable countries  ABC NEWS · 3 days
Mass abuse of the drug tramadol spans continents, from India to Africa to the Middle East. The problem is that advocates claimed it was a safer opioid, relieving pain with... more
Tramadol: `the other opioid crisis’ in the developing world  ABC NEWS · 3 days
Mass abuse of the drug tramadol spans continents, from India to Africa to the Middle East. The problem is that advocates claimed it was a safer opioid, relieving pain with... more
GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment  Science Magazine · 3 days
General control nonderepressible 2 (GCN2) is an environmental sensor controlling transcription and translation in response to nutrient availability. Although GCN2 is a putative therapeutic... more
Topology-dependent anomalous dynamics of ring and linear DNA are sensitive to cytoskeleton crosslinking  Science Magazine · 3 days
Cytoskeletal crowding plays a key role in the diffusion of DNA molecules through the cell, acting as a barrier to effective intracellular... more
Mass opioid abuse is `destabilizing’ world’s poorest nations  ABC NEWS · 3 days
Mass abuse of the drug tramadol spans continents, from India to Africa to the Middle East. The problem is that advocates claimed it was a safer opioid, relieving pain with little risk... more
Another opioid crisis is raging through the developing world  ABC NEWS · 3 days
Mass abuse of the drug tramadol spans continents, from India to Africa to the Middle East. The problem is that advocates claimed it was a safer opioid, relieving pain with... more
Menopause hormones causing breast cancer risks that may last decades  ABC NEWS · 3 days
Women who use certain types of hormones after menopause may still have an increased risk of developing breast cancer nearly two decades after they stop taking the pills more
Opioid billed as `safer’ is abused widely around the world  ABC NEWS · 3 days
Mass abuse of the drug tramadol spans continents, from India to Africa to the Middle East. The problem is that advocates claimed it was a safer opioid, relieving... more
Medical News Today: How two experimental Alzheimer's drugs reverse aging  MNT · 3 days
New research in mice reveals the molecular and genetic mechanisms through which two Alzheimer's drug candidates can reverse aging in general. more
Breast cancer risk from menopause hormones may last decades  ABC NEWS · 3 days
Women who use certain types of hormones after menopause may still have an increased risk of developing breast cancer nearly two decades after they stop taking the pills more
People willing to risk near-certain death for an HIV cure  SCIENCE DAILY · 3 days
People willing to risk near-certain death for an HIV cure; protecting individuals and families in genetic and psychiatric research, considerations for including pregnant women in research. more
A self-cleaning surface that repels even the deadliest superbugs  PHYS.ORG · 3 days
A team of researchers at McMaster University has developed a self-cleaning surface that can repel all forms of bacteria, preventing the transfer of antibiotic-resistant superbugs and other dangerous bacteria in... more
San Francisco hopes to improve care for people with mental illness living on streets  NEWS MEDICAL · 3 days
San Francisco Mayor London Breed has promised to tackle her city's homelessness crisis, a vexing situation involving drug abuse and... more
Human genetics evidence predictive of drug development success, study shows  NEWS MEDICAL · 3 days
A new drug candidate is more likely to be approved for use if it targets a gene known to be linked to the disease; a finding that can... more
Deadly 'superbugs' destroyed by molecular drills  nanowerk · 3 days
Motorized molecules activated by light target and drill through highly antibiotic resistant bacteria and kill them within minutes. The molecules can open bacteria to attack by drugs they previously resisted. The strategy could be applied to... more
Medications prescribed to children with chronic kidney disease may harm their kidneys  NEWS MEDICAL · 3 days
An analysis of records from primary care practices in the United Kingdom found that many children with kidney disease are prescribed medications that may... more
House drug pricing bill to reduce costs, improve access to life-saving therapies  NEWS MEDICAL · 3 days
H.R. 3, the Elijah E. Cummings Lower Drug Costs Now Act passed by the House of Representatives today introduces critically needed and significant steps... more
Introduction of drug amnesty bins is a good step towards minimizing harm at music festivals  NEWS MEDICAL · 3 days
The NSW Government’s introduction of amnesty bins at music festivals has been welcomed by Alex Greenwich, Member for... more
ASA thanks the House Ways and Means Committee for its framework to address surprise medical bills  NEWS MEDICAL · 3 days
Today, the American Society of Anesthesiologists (ASA) on behalf of its 54,000 members thanked the House... more
Caution is advised in interpreting the findings on radioiodine therapy for hyperthyroidism  NEWS MEDICAL · 3 days
Caution is advised in interpreting the findings of the recent JAMA Internal Medicine publication1 on radioactive iodine treatment for hyperthyroid patients and cancer mortality. more
People living with HIV are willing to risk near-certain death in clinical trial  NEWS MEDICAL · 3 days
Nearly one-quarter of people living with HIV were willing to risk near-certain death in a clinical trial, if volunteering for the trial... more
Influenza research could pave way for new and improved drugs, vaccines  NEWS MEDICAL · 3 days
Researchers at the Centenary Institute and the University of Sydney have discovered a key reason as to why the influenza virus is so effective at establishing... more
DigiM Solution receives FDA contract for microstructure imaging study  NEWS MEDICAL · 3 days
DigiM Solution LLC, a provider of microstructure characterization and optimization solutions and software, has received a contract from the Office of Generic Drugs of the U.S. Food and Drug Administration. more
New strategy could prevent side effects of targeted cancer treatment  NEWS MEDICAL · 3 days
Targeted, highly effective cancer treatments often produce debilitating side effects. This is the case with one commonly used therapy which works by blocking the epidermal growth factor receptor,... more
Scientists develop new method for targeted drug delivery to cancer cells  NEWS MEDICAL · 3 days
A team of scientists from Peter the Great St.Petersburg Polytechnic University together with their colleagues developed a method of targeted drug delivery to cancer cells. more
10-year results from clinical trial of extended letrozole therapy for women with HR+ breast cancer  NEWS MEDICAL · 3 days
In the updated results from NRG Oncology/NSABP B-42 trial through 10 years of observation, extending letrozole therapy for... more
Research could pave way for regenerative TBI-IV therapy  NEWS MEDICAL · 3 days
A team of researchers from the University of Georgia's Regenerative Bioscience Center has found that neural exosomes- "cargo" molecules within the nervous system that carry messages to the brain- can minimize or... more
Computerized CBT for depression could improve access to treatment, reduce waiting lists  NEWS MEDICAL · 3 days
Using a computerised version of cognitive-behavioural therapy to treat depression in children and young adults has the potential to improve access to psychological therapies and reduce waiting lists,... more
New study aims to improve walking in children with cerebral palsy  NEWS MEDICAL · 3 days
Noelle Moreau, Ph.D., PT, Associate Professor of Physical Therapy at LSU Health New Orleans School of Allied Health Professions, and Kristie Bjornson, PT, Ph.D., Associate Professor... more
New study finds 2 out of 5 antibiotic prescriptions could be unnecessary  NEWS MEDICAL · 3 days
A new study in the British Medical Journal published on December 11, 2019, finds that up to 2 in every 5 prescriptions in the... more
Discovery of novel mechanism by which certain breast cancers can metastasize  NEWS MEDICAL · 3 days
Researchers from the Baylor College of Medicine and Harvard Medical School have found a novel mechanism to explain the resistance of certain breast cancers that spread... more
Deadly 'superbugs' destroyed by molecular drills  PHYS.ORG · 3 days
Molecular drills have gained the ability to target and destroy deadly bacteria that have evolved resistance to nearly all antibiotics. In some cases, the drills make the antibiotics effective once again. more
Americans are taking fish antibiotics to save money  NEWS MEDICAL · 4 days
Alarming results from a new study show that people in the United States buying fish antibiotics online and consuming them because they’re more affordable than to go visit a doctor. The study... more
Molecular drills target and destroy deadly superbugs  NEWS MEDICAL · 4 days
Molecular drills have gained the ability to target and destroy deadly bacteria that have evolved resistance to nearly all antibiotics. In some cases, the drills make the antibiotics effective once again. more
Metabolic adaptation ensures survival of colon cancer cells  SCIENCE DAILY · 4 days
Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the... more
New drug targets to treat Nipah virus  SCIENCE DAILY · 4 days
Nipah virus, which is transmitted to humans from bats and pigs, has a high mortality rate and there are no licensed drugs against it. Now, researchers have used information on the structure of the... more
Eyeing 2020, House empowers Medicare to negotiate drug costs  ABC NEWS · 4 days
House Democrats have pushed through legislation that would empower Medicare to negotiate prescription drug prices and offer new benefits for seniors more
Scientists use novel technology for opening blood-brain barrier with implantable ultrasound  NEWS MEDICAL · 4 days
One of most potent drugs for treatment of glioblastoma, the most deadly type of brain tumor, can't be used in patients because of two problems. First,... more
ACA's new website aims to educate public about chiropractic services  NEWS MEDICAL · 4 days
The American Chiropractic Association has launched a new website to educate the public about non-drug pain relief and the chiropractic profession's holistic approach to health and improved function.... more
Researchers show restoration of medical records via satellite link for disaster medical support  NEWS MEDICAL · 4 days
The National Institute of Information and Communications Technology, Kochi Health Science Center and collaborating teams have developed a secure data backup system... more
Researchers examine p53-deficient colon cancer cells to identify how p53 impacts metabolic adaptation  NEWS MEDICAL · 4 days
Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to... more
Deadly 'superbugs' destroyed by molecular drills  SCIENCE DAILY · 4 days
Motorized molecules activated by light target and drill through highly antibiotic resistant bacteria and kill them within minutes. The molecules can open bacteria to attack by drugs they previously resisted. The strategy could be applied to... more
Hunting for new epilepsy drugs, and capturing lightning from space  Science Magazine · 4 days
On this week’s show: Tracing the roots of epilepsy, and watching lightning, terrestrial gamma ray bursts, and elves from the iInternational sSpace sStation more
Tropical flower offers potential new route for treating pancreatic cancer  SCIENCE DAILY · 4 days
An international team of scientists have made drug-like molecules inspired by a chemical found in a tropical flower, that they hope could in the future help to treat... more
A digital approach to proteins and cancer  SCIENCE DAILY · 4 days
What if scientists could create more effective drugs to treat cancers and other diseases by better targeting specific sites on proteins in the body? more
As epilepsy drugs fail nearly one-third of patients, scientists seek root causes of seizures  Science Magazine · 4 days
Leaps in gene sequencing and better animal models are changing how doctors understand, study, and sometimes treat epilepsy more
New book provides extensive research into health effects of football  NEWS MEDICAL · 4 days
The new book "Football as Medicine - Prescribing Football for Global Health Promotion" collates 15 years of research when describing the effects of football training on cardiovascular, metabolic... more
Virus multiplication in 3D  SCIENCE DAILY · 4 days
Vaccinia viruses serve as a vaccine against human smallpox and as the basis of new cancer therapies. Two studies now provide fascinating insights into their unusual propagation strategy at the atomic level. more
Study: 18% of outpatient antibiotic prescriptions written without a documented reason  NEWS MEDICAL · 4 days
A study of outpatient visits to health care providers in the United States during a one-year period suggests 18 percent of antibiotic prescriptions were written without... more
New antimicrobial polymer can kill bacteria resistant to common antibiotics  NEWS MEDICAL · 4 days
Researchers from Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, and Nanyang Technological University have designed an antimicrobial polymer that can kill bacteria resistant to... more
Researchers design polymer that can kill drug-resistant bacteria  PHYS.ORG · 4 days
Researchers from Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, and Nanyang Technological University (NTU) have designed an antimicrobial polymer that can kill bacteria resistant to commonly used... more
Pelosi drug bill up for House vote reflects a Trump idea  ABC NEWS · 4 days
When Donald Trump was running for the White House, he said he could save Medicare billions of dollars by negotiating prescription drug prices more
Anastrozole can be preventive drug-of-choice for women with high breast cancer risk  NEWS MEDICAL · 4 days
The Queen Mary University of London professor leading an international breast cancer study says anastrozole - rather than tamoxifen - should be the preventive drug-of-choice for... more
Study suggests antiarrhythmic drug as potential treatment for pulmonary arterial hypertension  NEWS MEDICAL · 4 days
High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a potentially fatal disease caused by obstruction of blood flow in the lungs. more
Researchers reprogram T cells to improve cancer immunotherapy  PHYS.ORG · 4 days
St. Jude Children's Research Hospital scientists have identified a new therapeutic strategy that enhanced cancer immunotherapy, slowed tumor growth and extended the lives of mice with cancer. The research appears today in... more
Radiation therapy alone found to be cost-effective for treatment of DCIS  NEWS MEDICAL · 4 days
Ductal carcinoma in-situ (DCIS) accounts for one-fifth of breast cancer cases in the United States, according to the American Cancer Society. more
Flipping the script on novel cancer therapy leads to insights into lupus  SCIENCE DAILY · 4 days
In the last decade, scientists discovered that blocking a key regulator of the immune system helped unleash the body's natural defenses against several forms... more
Yale scientists flip the script on novel cancer therapy to find new insights into lupus  NEWS MEDICAL · 4 days
In the last decade, scientists discovered that blocking a key regulator of the immune system helped unleash the... more
New software to help researchers study specific information about proteins  NEWS MEDICAL · 4 days
What if scientists could create more effective drugs to treat cancers and other diseases by better targeting specific sites on proteins in the body? more
New drug combo promises help for triple negative breast cancer patients  NEWS MEDICAL · 4 days
A new preclinical study on triple negative breast cancer (TNBC) reports that an experimental polo-like kinase 1 (PLK1) inhibitor shrank tumor four times more powerfully when... more
Health risks associated with NSAIDs as a factor for increased opioid prescribing  NEWS MEDICAL · 4 days
Patients with chronic pain caught between cardiovascular concerns about non-opioid analgesics and addiction risks of opioids, likely causing significant unmet need for pain relief. more
Accurate model of organ scarring using stem cells in a lab  SCIENCE DAILY · 4 days
A team has developed a 'scar in a dish' model that uses multiple types of cells derived from human stem cells to closely mimic the progressive... more
Addictions and drug interactions common among patients not disclosing their medication history  NEWS MEDICAL · 4 days
Some patients skip telling their doctors about the drugs and medications they are consuming. A new study shows that these patients are at a... more
Experimental Alzheimer’s drugs show promise  NEWS MEDICAL · 4 days
Researchers from Salk have found that two experimental drugs named CMS121 and J147 may improve memory functions and reduce the progression of memory decline and brain degeneration in mice models of Alzheimer’s disease (AD). The researchers published their... more
Help for teenagers who want to quit smoking  NEWS MEDICAL · 4 days
A new study published in the journal JAMA Pediatricsreports on the use of varenicline, a drug that helps smokers quit. The study is unique in that it targeted teenagers who wanted to... more
Non-drug therapies may reduce adverse outcomes in service members with chronic pain  NEWS MEDICAL · 5 days
A new study based on Veterans Affairs health records finds that non-drug therapies given to military service members with chronic pain may reduce the... more
Chemical found in tropical flower could help to treat deadly pancreatic cancer  NEWS MEDICAL · 5 days
An international team of scientists led by the University of Bath have made drug-like molecules inspired by a chemical found in a tropical flower,... more
Scientists evaluate mouse models used for developing new treatments for Huntington's disease  NEWS MEDICAL · 5 days
Huntington's disease (HD) is an incurable and fatal hereditary disease. Developing disease-modifying drugs to treat patients with HD depends on studying them in animal... more
NS1 DNA vaccination protects against Zika infection through T cell-mediated immunity in immunocompetent mice  Science Magazine · 5 days
The causal association of Zika virus (ZIKV) with microcephaly, congenital malformations in infants, and Guillain-Barré syndrome in adults highlights the... more
Identification of the hyaluronic acid pathway as a therapeutic target for facioscapulohumeral muscular dystrophy  Science Magazine · 5 days
Facioscapulohumeral muscular dystrophy (FSHD) is linked to epigenetic derepression of the germline/embryonic transcription factor DUX4 in skeletal muscle. However, the... more
[Research Articles] Distinct neural mechanisms for the prosocial and rewarding properties of MDMA  Science Magazine · 5 days
The extensively abused recreational drug (±)3,4-methylenedioxymethamphetamine (MDMA) has shown promise as an adjunct to psychotherapy for treatment-resistant psychiatric disease. It is unknown,... more
[Research Articles] Hair eruption initiates and commensal skin microbiota aggravate adverse events of anti-EGFR therapy  Science Magazine · 5 days
Epidermal growth factor receptor (EGFR)–targeted anticancer therapy induces stigmatizing skin toxicities affecting patients’ quality of life and therapy... more
[Research Articles] Caveolin-1-derived peptide limits development of pulmonary fibrosis  Science Magazine · 5 days
Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease with a median 5-year survival of ~20%. Current U.S. Food and Drug Administration–approved pharmacotherapies slow progression of IPF, providing hope... more
Medical News Today: Cancer: Common antibiotic may boost immune system  MNT · 5 days
New research in mice suggests that administering a common antibiotic before radiation therapy can help the immune system fight off cancer. more
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