Pharmaceuticals
Innovative compound offers a new therapeutic approach to treat multiple sclerosis  NEWS MEDICAL · 18 minutes
Multiple sclerosis is an autoimmune disease that affects more than 2.3 million people worldwide. This debilitating condition periodically shutters communication between the brain and other parts... more
A holistic approach key to minimize treatment complexity in patients with interstitial lung disease  NEWS MEDICAL · 54 minutes
Patients with interstitial lung disease—a group of disorders causing progressive scarring of lung tissue—are often prescribed various medications that specifically... more
Phase 1 data reinforce safety profile of new drug for treating Duchenne muscular dystrophy  NEWS MEDICAL · 54 minutes
Patients with Duchenne muscular dystrophy (DMD) have few treatment options. Medications currently available or in development either target only a... more
Besides the U.S., drug overdose mortality is also common in other high-income countries  NEWS MEDICAL · 54 minutes
Is the current American drug overdose epidemic an isolated phenomenon? Have other high-income countries experienced similar increases in drug overdose mortality, or... more
PET scans show biomarkers could spare some breast cancer patients from chemotherapy  SCIENCE DAILY · 1 hour
In an effort to further individualize therapy and avoid over-treating patients, researchers report a new study using PET scans has identified a biomarker that... more
Chemical added to consumer products impairs response to antibiotic treatment  SCIENCE DAILY · 6 hours
Triclosan exposure may inadvertently drive bacteria into a state in which they are able to tolerate normally lethal concentrations of antibiotics -- including those antibiotics that are commonly... more
Design principles for disease-sensing nanomaterials  SCIENCE DAILY · 9 hours
A new article outlines novel design guidance that could rapidly advance development of disease-sensing nanomaterials for use in new drug development. more
New paper provides design principles for disease-sensing nanomaterials  PHYS.ORG · 9 hours
Scientists have long sought to develop drug therapies that can more precisely diagnose, target and effectively treat life-threatening illness such as cancer, cardiovascular and autoimmune diseases. One promising approach is the design... more
No, scientists didn't find a cure for HPV: Here’s what you need to know  ABC NEWS · 10 hours
A viral news story claimed a group of Mexican scientists found a cure for human papillomavirus and the cancers it... more
A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels  Science Magazine · 10 hours
Potassium (K+) channels have been evolutionarily tuned for activation by diverse biological stimuli, and pharmacological activation is thought to target... more
American drug overdose death rates the highest among wealthy nations  SCIENCE DAILY · 11 hours
A new study found that the United States has the highest drug overdose death rates among a set of high-income countries. The study found that drug overdose death... more
Saffron may be a promising herbal alternative for treating ADHD  NEWS MEDICAL · 12 hours
A new short-term pilot study in children and teens 6-17 years old with attention-deficit hyperactivity disorder has shown saffron to be as effective at controlling symptoms as methylphenidate,... more
New compound offers superior therapeutic approach to treat MS  SCIENCE DAILY · 12 hours
Previous studies have shown that estrogens and estrogen-like compounds reduce multiple sclerosis-like inflammation and disability in mice. At first glance these treatments appear promising, but they carry a host of... more
New iridium catalyst enables efficient selective synthesis of valuable drug ingredients  SCIENCE DAILY · 12 hours
The researchers found that transient formation of hydrogen bonding between a substrate and the catalyst induced such high segregation in the reaction. By using inexpensive and... more
CASSINI Trial publishes data on preventing blood clots in cancer patients  SCIENCE DAILY · 13 hours
Researchers have published the first clinical study investigating the use of the direct oral anticoagulant, rivaroxaban, to prevent blood clots in patients with cancer at high-risk.... more
HIV drug could improve recovery after stroke  Science Magazine · 13 hours
A protein that may hinder the brain’s regrowth after damage points researchers to an unexpected treatment more
Reduced antibody adaptability may make the elderly more vulnerable to influenza  NEWS MEDICAL · 13 hours
The influenza vaccine may be less effective in the elderly because their B cells are less capable of producing antibodies that can adapt to protect against... more
New 'smart drug' shows promise for metastatic triple-negative breast cancer  SCIENCE DAILY · 14 hours
A clinical trial has found that patients responded to a new 'smart drug' for women with an aggressive form of breast cancer. more
Antibody therapy training phagocytes to destroy tumors now tested on patients  SCIENCE DAILY · 14 hours
An immunotherapeutic antibody therapy re-educates macrophages to activate passivated cytotoxic T cells to kill cancer. The antibody therapy prevented the growth of tumours in several mouse... more
Synthesizing useful compounds without forming unwanted chiral partners  PHYS.ORG · 14 hours
Did you know that more than half of the drugs currently in use are chiral, potentially resulting in two different responses in the body? Chiral compounds are pairs of molecules that are... more
Novel ratiometric fluorescent probe for studying cellular activity of anticancer drug  NEWS MEDICAL · 14 hours
NUS chemists have developed a novel ratiometric fluorescent probe for studying cellular activity of the clinically important anticancer drug cisplatin for next generation drug development. more
Intensive therapy during early stages of MS leads to better long-term outcomes  NEWS MEDICAL · 14 hours
New findings by researchers at Cardiff University suggest that intensive therapy during the early stages of multiple sclerosis (MS) leads to better long-term outcomes... more
Squid could provide an eco-friendly alternative to plastics  nanowerk · 15 hours
Self-healing fabric, abrasion-resistant coatings, precision drug delivery and smart textiles are among the potential applications of squid 'ring tooth' protein. more
Bacteria can survive starvation in zombie mode  PHYS.ORG · 15 hours
Bacteria that are exposed to a hostile environment, for example with antibiotics or very few nutrients, can sometimes survive by 'going to sleep." Biologists from the University of Amsterdam (UvA) have discovered an unknown,... more
PENTAX Medical introduces new electrosurgical and argon plasma coagulation platforms  NEWS MEDICAL · 16 hours
PENTAX Medical announces the addition of new dedicated electrosurgical and argon plasma coagulation platforms – the ENDO ARC and ENDO PLUS – to its therapeutic accessories range. more
New therapeutic approach to combat African sleeping sickness  PHYS.ORG · 17 hours
Scientists working in a range of disciplines joined forces to identify a new approach to combat African sleeping sickness. Fundamental research undertaken under the supervision of Professor Ute Hellmich of Johannes Gutenberg... more
More states say doctors must offer overdose reversal drug along with opioids  NEWS MEDICAL · 18 hours
In a growing number of states, patients who get opioids for serious pain may leave their doctors' offices with a second prescription — for... more
The United States records highest drug overdose death rates  NEWS MEDICAL · 22 hours
In the most comprehensive international comparison of its kind, a USC study found that the United States has the highest drug overdose death rates among a set of high-income countries. more
Drug increases melanin production in some people with albinism  NEWS MEDICAL · 22 hours
A small pilot clinical study at the National Eye Institute suggests that the drug nitisinone increases melanin production in some people with oculocutaneous albinism type 1B, a rare genetic disease... more
Why melanoma tumors in the brain may be worse?  NEWS MEDICAL · 1 day
Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites. more
Researchers discover a new promising target to improve HIV vaccines  NEWS MEDICAL · 1 day
In the quest to develop an effective HIV vaccine, researchers have focused attention on identifying and targeting the region of the virus's outer envelope where a lineage of... more
Some drug combinations may be more effective than others for schizophrenic patients  NEWS MEDICAL · 1 day
Patients with schizophrenia are often treated with more than one type of psychiatric medication, but a new study suggests that some combinations may be... more
Study quantifies hepatic and intestinal mRNA expression of Ugt isoforms in rats  NEWS MEDICAL · 1 day
In pharmaceutical companies, rats are used commonly in nonclinical studies to investigate the safety, efficacy, and pharmacokinetic profiles of drug candidates before they are... more
Mississippi woman pleads guilty in massive pharmacy fraud  ABC NEWS · 1 day
A Mississippi woman charged in a pharmacy fraud case that prosecutors say reaped than $200 million pleads guilty to charges in the csae more
Melanoma brain metastases are immunosuppressive with treatment-resistant metabolism  SCIENCE DAILY · 1 day
Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites. Researchers report that the heavy reliance of these... more
Gene therapy durably reverses congenital deafness in mice  SCIENCE DAILY · 1 day
Scientists have managed to restore hearing in an adult mouse model of DFNB9 deafness -- a hearing disorder that represents one of the most frequent cases of congenital genetic deafness. Individuals with... more
New insight on potent HIV antibody could improve vaccine design  SCIENCE DAILY · 1 day
A new observation highlights the importance of previously unstudied mutations that arises early in bnAbs, giving the antibodies the flexibility to adapt to changes in the virus's outer... more
Nurse charged in fatal drug-swap error pleads not guilty  ABC NEWS · 1 day
A Tennessee nurse charged with reckless homicide after a medication error killed a patient has pleaded not guilty more
[Editors' Choice] Immunity to CRISPR-Cas9  Science Magazine · 1 day
Evaluation of patient serum samples commonly reveals preexisting anti-Cas9 antibodies and T cells. more
[Focus] Challenges for mesenchymal stromal cell therapies  Science Magazine · 1 day
Clinical trials of mesenchymal stromal cell therapies reveal a challenging heterogeneous landscape, including diverse therapeutic targets, patient categories, cell sources, and potential mechanisms of action. more
Cocktail of common antibiotics can fight resistant E. coli  SCIENCE DAILY · 1 day
Scientists have discovered that a combination of two common antibiotics is able to eliminate multi-drug resistant E. coli causing urinary tract infections. This combination treatment could become an effective measure... more
Drug 'librarian' discovers new compound that may thwart common surgery complication  SCIENCE DAILY · 1 day
In a strategic search, scientists created and screened a library of 45,000 new compounds containing chemical elements of widely used immune system suppressants, and say they... more
New compound could help treat ovarian cancer  SCIENCE DAILY · 1 day
Scientists have discovered a compound that could be more effective in treating certain cancers than standard chemotherapy. more
Acetaminophen significantly reduced in-hospital delirium  SCIENCE DAILY · 1 day
Patients treated with acetaminophen demonstrated a significant reduction in in-hospital delirium. Moreover, those given acetaminophen also were more likely to have shorter stays in the intensive care unit, less breakthrough pain. Those patients who did experience delirium had... more
Peer support, healing hands may curb prescription opioid misuse  SCIENCE DAILY · 1 day
A program offering group support, acupuncture, mindfulness, massage and gentle exercise may help prevent patients on prescription opioids from spiraling down to drug misuse, overdose and death, according to a... more
New therapeutic approach to combat African sleeping sickness  SCIENCE DAILY · 1 day
Scientists working in a range of disciplines joined forces to identify a new approach to combat African sleeping sickness. Fundamental research has revealed a promising strategy to develop a suitable agent. more
Medical News Today: Bacteria living on insects could provide new antibiotics  MNT · 1 day
Insects harbor bacteria that protect them from infection. Tapping this source could yield new antibiotics to combat the growing threat of drug resistance. more
Nitisinone increases melanin in people with albinism  SCIENCE DAILY · 1 day
A small pilot clinical study suggests that the drug nitisinone increases melanin production in some people with oculocutaneous albinism type 1B (OCA-1B), a rare genetic disease that causes pale skin and hair and poor... more
Targeting DDR2 enhances tumor response to anti-PD-1 immunotherapy  Science Magazine · 1 day
While a fraction of cancer patients treated with anti–PD-1 show durable therapeutic responses, most remain unresponsive, highlighting the need to better understand and improve these therapies. Using an in vivo screening approach... more
Bottlebrush-architectured poly(ethylene glycol) as an efficient vector for RNA interference in vivo  Science Magazine · 1 day
Nonhepatic delivery of small interfering RNAs (siRNAs) remains a challenge for development of RNA interference–based therapeutics. We report a noncationic vector wherein linear poly(ethylene... more
BGU develops new AI platform for monitoring and predicting ALS progression  NEWS MEDICAL · 1 day
Ben-Gurion University of the Negev has developed a new artificial intelligence (AI) platform for monitoring and predicting progression of neurodegenerative diseases to help identify markers for... more
Combination of common antibiotics can eliminate multi-drug resistant E. coli  NEWS MEDICAL · 1 day
A group of scientists in Denmark is trying to get one step ahead in the battle against antibiotic resistance. more
Immunotherapeutic antibody therapy to kill cancer has now progressed to patient testing  NEWS MEDICAL · 1 day
Developed by researchers at the University of Turku in Finland, an immunotherapeutic antibody therapy re-educates macrophages to activate passivated cytotoxic T cells to kill... more
New AI can identify, predict development of different combinations of cancer symptoms  NEWS MEDICAL · 1 day
Cancer patients who undergo chemotherapy could soon benefit from a new AI that is able to identify and predict the development of different combinations... more
Medical News Today: Can we halt cellular aging? New drug combo shows promise  MNT · 2 days
In the first clinical trial in humans, researchers test a promising drug combination that could help fight the effects of cellular aging. more
Blueprint for treating a deadly brain tumor  SCIENCE DAILY · 2 days
In a study of mice and human brain tumors researchers searched for new treatments by exploring the reasons why some patients with gliomas live remarkably longer than others. The results suggested that certain patients'... more
What plant proteins can tell us about Alzheimer's  PHYS.ORG · 2 days
Alzheimer's disease and other forms of dementia are a growing burden on society and a leading cause of death among the elderly. There is no cure. more
Drug 'librarian' discovers new compound that may thwart common surgery complication  PHYS.ORG · 2 days
In a strategic search, Johns Hopkins scientists created and screened a library of 45,000 new compounds containing chemical elements of widely used immune system suppressants, and... more
Study shows therapeutic potential of VEGF-A mRNA for regenerative angiogenesis in humans  NEWS MEDICAL · 2 days
An international team of researchers from academia and the biopharma industry has published a Phase 1a/b study, showing the therapeutic potential of mRNA encoding for vascular... more
Researchers find potential therapeutic strategy to treat Alzheimer's  NEWS MEDICAL · 2 days
Researchers from the Institute of Neurosciences of the University of Barcelona (UBNeuro) have identified a potential therapeutic strategy to treat Alzheimer's, according to a study published in Journal of Neuroscience. more
Mogrify to accelerate novel IP and cell therapies using $3.7m USD funding  NEWS MEDICAL · 2 days
Mogrify today announced a second close on its seed funding, bringing the total raised to $3.7 million USD, and the appointment of Darrin Disley... more
First gene therapy operation for macular degeneration is a success  NEWS MEDICAL · 2 days
A new treatment is the first to target the underlying genetic cause of AMD, which affects more than 600,000 people in the UK alone. more
New compound could help treat ovarian cancer  PHYS.ORG · 2 days
Scientists from the University of Sheffield have discovered a compound that could be more effective in treating certain cancers than standard chemotherapy. more
Investigators figure out how to block new antibiotic resistance gene  PHYS.ORG · 2 days
A new antimicrobial-resistance gene, VCC-1, a ß-lactamase gene, has been discovered in benign close relatives of virulent Vibrio cholerae, which causes cholera. Now, a team of Canadian researchers... more
Machine learning technique helps predict which asthma patients respond to corticosteroid therapy  NEWS MEDICAL · 2 days
Physicians will be able to predict which of their patients with severe asthma are likely to benefit from treatment with systemic corticosteroids -- and... more
University of Dundee partners with Takeda to develop new treatments for tau pathology  NEWS MEDICAL · 2 days
The University of Dundee Drug Discovery Unit has announced a partnership with Takeda, Japan's largest pharmaceutical company, to develop possible new therapeutic... more
Researchers uncover biochemical pathway that may help identify drugs to treat Alzheimer's  NEWS MEDICAL · 2 days
Researchers have uncovered an enzyme and a biochemical pathway they believe may lead to the identification of drugs that could inhibit the production of... more
Novel preclinical model mimics persistent interneuron loss seen in preterm infants  NEWS MEDICAL · 2 days
Research-clinicians at Children's National Health System have created a novel preclinical model that mimics the persistent interneuron loss seen in preterm human infants, identifying interneuron subtypes... more
Newly developed gene therapy helps decelerate aging process  NEWS MEDICAL · 2 days
Aging is a leading risk factor for a number of debilitating conditions, including heart disease, cancer and Alzheimer's disease, to name a few. This makes the need for anti-aging therapies all the... more
Influenza vaccine may be less effective in elderly patients, finds study  NEWS MEDICAL · 2 days
The influenza vaccine may be less effective in the elderly because their B cells are less capable of producing antibodies that can adapt to protect against... more
Researchers explain why T cells lose their protective ability in inflamed tissues  NEWS MEDICAL · 2 days
Regulatory T cells make sure that immune responses are not too strong and that inflammation is inhibited. This makes them highly interesting for therapies... more
New therapeutic approach to treating osteoarthritis  SCIENCE DAILY · 2 days
Researchers have developed a new way to deliver treatment for cartilage regeneration. more
Dose of vitamin C helps gold nanowires grow  SCIENCE DAILY · 2 days
Scientists discover a method to turn stubby gold nanorods into gold nanowires of impressive length. The metal wires could be valuable for sensing, diagnostic, imaging and therapeutic applications. more
Common acid reflux drugs tied to elevated risk for kidney disease  NEWS MEDICAL · 2 days
Proton pump inhibitors, which include well-known brand names Prilosec, Nexium and Prevacid, are among the most commonly prescribed medications in the world. Approximately 10 percent of... more
First molecular test predicts treatment response for kidney cancer  NEWS MEDICAL · 2 days
Immunotherapy drugs such as PD-L1 checkpoint inhibitors represent the front-line treatment for kidney cancer. But immunotherapy is expensive, benefits only a subset of patients and is futile in the majority... more
A lack of antibody diversity may make the elderly more susceptible to the flu  SCIENCE DAILY · 2 days
The influenza vaccine may be less effective in the elderly because their B cells are less capable of producing antibodies... more
New model mimics persistent interneuron loss seen in prematurity  SCIENCE DAILY · 2 days
Research-clinicians created a novel preclinical model that mimics the persistent interneuron loss seen in preterm human infants, identifying interneuron subtypes that could become future therapeutic targets to prevent or lessen... more
Antibiotic resistances spread faster than thought, aquaculture study reveals  SCIENCE DAILY · 2 days
By studying fish raised in aquaculture, researchers have shed new light on the mechanisms by which antibiotic resistance genes are transferred between bacteria. According to their study, those mechanisms are... more
How to block new antibiotic resistance gene  SCIENCE DAILY · 2 days
A new antimicrobial-resistance gene, VCC-1, a beta-lactamase gene, has been discovered in benign close relatives of virulent Vibrio cholerae, which causes cholera. Now, a team of Canadian researchers has found a way to block... more
Total synthesis of marine antitumor agents trabectedin and lurbinectedin  SCIENCE DAILY · 2 days
With its vast numbers of different lifeforms, the sea is a largely unexplored source of natural products that could be starting points for new pharmaceuticals, such as the antitumor drugs... more
Micro-control of liver metabolism  SCIENCE DAILY · 2 days
A new discovery has shed light on small RNAs called microRNAs in the liver that regulate fat and glucose metabolism. Research shows that a molecular anticipation, during fast to re-feed transition, is essential for capping glucose production by the liver.... more
Gene therapy restores hearing in mice with congenital genetic deafness  NEWS MEDICAL · 2 days
In collaboration with the universities of Miami, Columbia and San Francisco, scientists from the Institut Pasteur, Inserm, CNRS, Collège de France, Sorbonne University and the University of Clermont... more
Anti-cancer immunotherapy could be used to fight HIV  NEWS MEDICAL · 2 days
Researchers at the University of Montreal Hospital Research Centre have shown that immunotherapy treatments against cancer could reduce the amount of virus that persists in people on triple therapy. more
Hospital, doctor face 3 new lawsuits over drug doses, deaths  ABC NEWS · 2 days
Three more wrongful-death lawsuits have been filed against an Ohio hospital system and a doctor accused of ordering potentially fatal doses of pain medication for dozens of patients more
Unique gene therapy approach paves new way to tackle rare, inherited diseases  NEWS MEDICAL · 2 days
Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function... more
High court denies Maryland appeal of drug price-gouging law  ABC NEWS · 3 days
The U.S. Supreme Court has denied a Maryland appeal to uphold the state's law against pharmaceutical price gouging more
Medical News Today: Self-destruction system in TB bacteria may lead to 'perfect drug'  MNT · 3 days
Scientists zoom in on the 'toxin-antitoxin' system that the tuberculosis bacterium naturally contains, in the hope that it can help design better... more
CRISPR/Cas9 therapy can suppress aging, enhance health and extend life span in mice  SCIENCE DAILY · 3 days
Researchers have developed a new gene therapy to help decelerate the aging process. The findings highlight a novel CRISPR/Cas9 genome-editing therapy that... more
Preventing 'cell wall remodeling' may hold key to defeating intransigent super bugs  PHYS.ORG · 3 days
B. multivorans is a notorious pathogen that can cause infections such as pneumonia in immune-compromised individuals with underlying lung diseases, including cystic fibrosis. This... more
Novel gene therapy approach creates new route to tackle rare, inherited diseases  PHYS.ORG · 3 days
Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function... more
Climate-friendly labriculture depends on an energy revolution, study says  PHYS.ORG · 3 days
Currently proposed types of lab-grown meat cannot provide a cure-all for the detrimental climate impacts of meat production without a large-scale transition to a decarbonised energy system, a new study... more
Oral antifungal drug used to treat yeast infections linked to higher rates of miscarriage  SCIENCE DAILY · 3 days
A commonly used medication, fluconazole, used to treat vaginal yeast infections, is linked to higher rates of miscarriage if used... more
Medical News Today: Depression: Gene-activating drug reverses symptoms in mice  MNT · 3 days
Researchers have reversed symptoms of depression, such as anhedonia and behavioral despair, in male mice with a drug that activates a gene they call SIRT1. more
Depression: Gene-activating drug reverses symptoms in mice  MNT · 3 days
Researchers have reversed symptoms of depression, such as anhedonia and behavioral despair, in male mice with a drug that activates a gene they call SIRT1. more
Brain imaging indicates potential success of drug therapy in depressive patients  NEWS MEDICAL · 3 days
Working with international partners, a MedUni Vienna research group has shown that imaging techniques carried out prior to treatment indicate the potential success of drug therapy... more
Total synthesis of marine antitumor agents trabectedin and lurbinectedin  PHYS.ORG · 3 days
With its vast numbers of different lifeforms, the sea is a largely unexplored source of natural products that could be starting points for new pharmaceuticals, such as the antitumor drugs... more
Using Therapy Dogs to Reduce Stress and Improve Emotional Well-Being in Vulnerable Individuals
NEWS MEDICAL
Insulin in a pill from MIT researchers
NEWS MEDICAL
Time-lapse microscopy helps reveal brake mechanism in Streptomyces lifecycle
PHYS.ORG
Ingestible, expanding pill monitors the stomach for up to a month
SCIENCE DAILY
'Superbug gene' found in one of the most remote places on Earth
PHYS.ORG
The curious link between brain diseases and blue-green algae
PHYS.ORG
Lab-Scale Clarification of Mammalian Cell Cultures Expressing Recombinant Antibodies
NEWS MEDICAL
Trump zeroes in on surprise medical bills in White House chat with patients, experts
NEWS MEDICAL
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