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Family behind drug company sued over toll of opioids
ABC NEWS Members of the family behind a drug company are being sued over the toll of prescription opioid painkillers 54 minutes
The composition of gut bacteria almost recovers after antibiotics
SCIENCE DAILY The use of antibiotics has long been linked to deprivation of gut bacteria. Now, a new study shows that the composition and function of gut bacteria can recover after antibiotic... 2 hours
Scientists capture images of antibodies working together against malaria
PHYS.ORG Scientists investigating how the human immune system defends against malaria have uncovered a rare phenomenon: antibodies working together to bind to a vulnerable spot on the parasite. 3 hours
New liquid biopsy test confirms remission in patients with HPV-associated oropharyngeal cancer
NEWS MEDICAL A highly sensitive blood test that detects minute traces of cancer-specific DNA has been shown to accurately determine whether patients with HPV-related oropharyngeal squamous... 5 hours
'Mushrooms' and 'brushes' help cancer-fighting nanoparticles survive in the body
PHYS.ORG For a number of innovative and life-saving medical treatments, from organ replacements and skin grafts to cancer therapy and surgery, success often depends on slipping past or fending... 6 hours
FDA targets 465 websites that sell potentially dangerous, unapproved drugs
NEWS MEDICAL The U.S. Food and Drug Administration, in partnership with international regulatory and law enforcement agencies, acted this week to target 465 websites that illegally sell potentially dangerous, unapproved... 6 hours
Intake of painkillers during pregnancy linked to early puberty in future offspring
NEWS MEDICAL The more weeks a women takes pain-reliving medication during pregnancy, the earlier their daughters enter puberty. This is shown by a new study from... 6 hours
Gut bacterial community of healthy adults recovers after short-term exposure to broad-spectrum antibiotics
NEWS MEDICAL The trillions of bacteria in the human gut affect our health in multiple ways including effects on immune functions and metabolism. 6 hours
Painkillers during pregnancy can bring forward puberty in girls
SCIENCE DAILY The more weeks a women takes pain-reliving medication during pregnancy, the earlier their daughters enter puberty. This is shown by a new study. As the first in the world, researchers... 7 hours
First immunotherapy success for triple-negative breast cancer
SCIENCE DAILY New research has shown that by using a combination of immunotherapy and chemotherapy the body's own immune system can be tuned to attack triple-negative breast cancer, extending survival. 7 hours
The Latest: University of California workers start strike
ABC NEWS More than 15,000 University of California radiology technicians, pharmacists and other medical workers have started a three-day strike to protest outsourcing and demand higher wages 8 hours
Breakthrough test screens for all known bacterial infections
SCIENCE DAILY Scientists have developed the first diagnostic platform that can simultaneously screen for all known human pathogenic bacteria as well as markers for virulence and antibiotic resistance. A study provides details on the... 8 hours
The smell of lavender is relaxing, science confirms
SCIENCE DAILY A new review reveals how lavender mellows us out -- and why some day psychiatrists and surgeons might be prescribing patients a whiff of the purple stuff. 8 hours
AbbVie rheumatoid arthritis drug succeeds in late stage trial
REUTERS AbbVie Inc on Tuesday said its experimental rheumatoid arthritis (RA) treatment showed significant improvement in physical function, pain... 9 hours
Antipsychotic Drugs Don't Ease ICU Delirium
NPR Though widely prescribed in hospital intensive care units to treat hallucinations and other signs of delirium, Haldol and similar drugs are no better than a placebo for such patients, a study finds. 9 hours
New diagnostic platform simultaneously screens for all known pathogenic bacteria
NEWS MEDICAL Scientists at the Center for Infection and Immunity in the Columbia University Mailman School of Public Health have developed the first diagnostic platform that can simultaneously screen for... 12 hours
New type of molecule shows early promise against treatment-resistant prostate cancer
NEWS MEDICAL A new type of molecule blocks the action of genes that drive the growth of therapy-resistant prostate cancer, a new study finds. 12 hours
Breakthrough test screens for all known bacterial infections
PHYS.ORG Scientists at the Center for Infection and Immunity (CII) in the Columbia University Mailman School of Public Health have developed the first diagnostic platform that can simultaneously screen for all known human... 13 hours
Medical News Today: Immunotherapy successful against deadly breast cancer
MNT A new trial confirms that a combination of immunotherapy and chemotherapy boosts survival rates for people with triple-negative breast cancer. 14 hours
Advanced breast cancer patients can benefit from immunotherapy-chemotherapy combination
NEWS MEDICAL Patients with an aggressive form of advanced breast cancer can benefit from immunotherapy when used in combination with chemotherapy as first-line treatment, according to the results of a large international... 15 hours
Study reveals new treatment option for women with advanced breast cancer resistant to hormone therapy
NEWS MEDICAL Treatment with the cyclin dependent kinase 4/6 inhibitor palbociclib achieves a clinically meaningful improvement in overall survival in... 15 hours
AbbVie’s U-ACHIEVE Phase 2b/3 dose-ranging study improves outcomes in patients with ulcerative colitis
NEWS MEDICAL AbbVie, a research-based global biopharmaceutical company, today announced positive results from U-ACHIEVE, an ongoing Phase 2b/3 dose-ranging study evaluating upadacitinib, an investigational... 16 hours
Construction is underway for second proton therapy system at Siteman Cancer Center
NEWS MEDICAL Mevion Medical System announces that construction is underway for a second proton therapy system at Siteman Cancer Center at Barnes-Jewish Hospital and Washington University... 17 hours
Immunotherapy is better than chemotherapy as first-line treatment for advanced head and neck cancer
NEWS MEDICAL Immunotherapy on its own is better than aggressive chemotherapy as a first-line treatment for advanced head and neck cancer, according... 18 hours
Salk researchers advance sonogenetics technology for treating neurological conditions
NEWS MEDICAL The emerging technology of sonogenetics--a technique where cells are controlled by sound--offers the potential to one day replace pharmaceutical drugs or invasive surgical treatments for neurological conditions like epilepsy, Parkinson's... 18 hours
Common antibodies associated with myocardial infarction
NEWS MEDICAL Levels of antiphospholipid antibodies, which are associated with rheumatic diseases, are also elevated in myocardial infarction without any autoimmune co-morbidity, a study from Karolinska Institutet in Sweden published in The Annals of Internal Medicine reports. 18 hours
SLU researcher seeks to find solutions for 'chemo brain' symptoms and side effects of opioids
NEWS MEDICAL With a pair of RO1 grants from the National Institutes of Health, pain researcher Daniela Salvemini, Ph.D., will... 18 hours
NCI grant awarded to Abramson Cancer Center to study CAR T cells In solid tumors
NEWS MEDICAL A new program project grant from the National Cancer Institute will fund research by the Translational Center of... 18 hours
Radiotherapy combined with androgen-deprivation therapy improves overall survival up to 10 years
NEWS MEDICAL The long-term follow up of the NRG Oncology trial RTOG 9408, studying the addition of short-term androgen-deprivation therapy (ADT) to radiotherapy (RT) for men... 18 hours
Cancer treatment may undergo a paradigm shift to immunotherapy soon
NEWS MEDICAL Immunotherapy when used for cancer treatment could extend life longer finds studies. Experts have explained that until now immunotherapy was reserved as a last resort for most patients... 19 hours
Patient-reported data confirms efficacy of brachytherapy alone in intermediate risk prostate cancer
NEWS MEDICAL Oncology trial RTOG 0232 comparing a combined treatment of external beam therapy and brachytherapy to transperineal interstitial permanent brachytherapy alone indicate a significantly different... 20 hours
Research offers new hope to men who received childhood cancer treatment
NEWS MEDICAL Researchers have discovered a way to grow human stem cells destined to become mature sperm in an effort to provide fertility options later in life to... 20 hours
Antibodies linked to heart attacks
SCIENCE DAILY Levels of antiphospholipid antibodies, which are associated with rheumatic diseases, are also elevated in myocardial infarction without any autoimmune co-morbidity, a study reports. 1 day
Researchers wake-up DNA from soil bacteria to discover novel acid antibiotic
SCIENCE DAILY Scleric Acid has been discovered by capturing and engineering a DNA fragment from soil bacteria Streptomyces sclerotialus, and could help fight bacterial infections. 1 day
New mechanism of action in a first-line drug for diabetes
SCIENCE DAILY Researchers have discovered a mechanism of action underlying a widely used diabetes drug, which may expand its indications for use, as well as open new inroads in pharmaceutical... 1 day
New drug combination destroys chemo-resistant blood cancer
SCIENCE DAILY Researchers have developed a promising targeted strategy to treat chemotherapy-resistant acute myeloid leukemia (AML) and a diagnostic test to determine which AML patients would most likely benefit from this treatment. In a mouse model,... 1 day
Cells that change jobs to fight diabetes
SCIENCE DAILY Diabetes is characterized by persistent high blood sugar levels that occur when certain cells in the pancreas -- the insulin-producing cells -- are destroyed or are no longer able to secrete insulin. Researchers have... 1 day
Medical News Today: Is hair loss a side effect of metformin?
MNT Doctors prescribe metformin to treat people with type 2 diabetes or polycystic ovary syndrome (PCOS). In rare cases, metformin may cause hair loss. Learn more here. 1 day
Researchers develop promising targeted strategy to treat chemo-resistant blood cancer
NEWS MEDICAL Researchers from The Ottawa Hospital and the University of Ottawa have developed a promising targeted strategy to treat chemotherapy-resistant acute myeloid leukemia and a diagnostic test to determine... 1 day
Drug cocktail that increases lifespan discovered
NEWS MEDICAL A team of researchers led by Principal Investigator Dr Jan Gruber from Yale-NUS College has discovered a combination of pharmaceutical drugs that not only increases healthy lifespan in the microscopic worm Caenorhabditis elegans (C. elegans), but... 1 day
Antipsychotic Drugs Don't Ease ICU Delirium Or Dementia
NPR Though widely prescribed in hospital intensive care units to treat hallucinations and other signs of delirium, Haldol and similar drugs are no better than a placebo for such patients, a study finds. 1 day
Researchers wake-up DNA from soil bacteria to discover novel acid antibiotic
PHYS.ORG Scleric Acid has been discovered by capturing and engineering a DNA fragment from soil bacteria Streptomyces sclerotialus, and could help fight bacterial infections—by researchers at the... 1 day
Targeted drug and hormone therapy combination extends breast cancer survival
NEWS MEDICAL Combining a targeted drug with hormone therapy substantially extends survival for women with advanced breast cancer, a major clinical trial has found. 1 day
Home-based biofeedback therapy is effective option for tough-to-treat constipation
SCIENCE DAILY Biofeedback therapy used at home is about 70 percent effective at helping patients learn how to coordinate and relax bowel muscles and relieve one of the most difficult-to-treat types of... 1 day
Study describes cellular factories in greater detail
PHYS.ORG Many important natural products such as antibiotics, immunosuppressants and cancer drugs are derived from microorganisms. These natural products are often small proteins or peptides generated in the cell by NRPS enzymes similar to a... 1 day
People with periodontal disease less likely to reach healthy blood pressure ranges
NEWS MEDICAL People with high blood pressure taking medication for their condition are more likely to benefit from the therapy if they have good oral health,... 2 days
Medical News Today: Antibiotic plus probiotic combination may kill off superbugs
MNT A combination of antibiotics and probiotics has successfully wiped out MRSA and Pseudomonas aeruginosa — two drug resistant bacteria. 2 days
FOTIVDA expected to be included in new ESMO guidelines for advanced renal cell carcinoma
NEWS MEDICAL EUSA Pharma welcomes the news that FOTIVDA (tivozanib) is expected to be included in the upcoming European Society of Medical... 2 days
Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer
NEWS MEDICAL Genentech, a member of the Roche Group, today announced positive results from the Phase III IMpower130 study of Tecentriq (atezolizumab) plus chemotherapy... 2 days
Phase III LONSURF study shows progression-free survival in patients with refractory metastatic gastric cancer
NEWS MEDICAL Servier and Taiho Oncology, Inc. (U.S.), a subsidiary of Taiho Pharmaceutical Co., Ltd. (Japan), jointly announced today clinical data from... 2 days
Researchers produce artificial antibody capable of blocking prions in the laboratory
NEWS MEDICAL Prion diseases affect the brain, causing neurodegenerative problems that always lead to death. They attracted attention in the late 1990s due to the "Mad Cow" scare. 2 days
Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas
NEWS MEDICAL Merck, known as MSD outside the United States and Canada, today announced the first presentation of preliminary data from a... 2 days
Maintenance therapy with olaparib improves progression-free survival in advanced ovarian cancer patients
NEWS MEDICAL Two-year maintenance therapy with olaparib, a PARP (poly ADP ribose polymerase) inhibitor, olaparib, led to a substantial, unprecedented improvement in progression-free survival (PFS) in... 2 days
Roche lands Tecentriq trial win, still trails Merck in lung cancer
REUTERS Roche's Tecentriq plus chemotherapy boosted lung cancer patients' survival by nearly five months, study... 2 days
Takeda presents Vedolizumab phase 3 VISIBLE 1 trial results for treatment of moderately to severely active ulcerative colitis
NEWS MEDICAL Takeda Pharmaceutical Company Limited today announced results from the phase 3 VISIBLE... 2 days
Pfizer announces PALOMA-3 trial results in patients with HR+, HER2- metastatic breast cancer
NEWS MEDICAL Pfizer Inc. today announced detailed overall survival data from the PALOMA-3 trial, which evaluated IBRANCE (palbociclib) in combination with fulvestrant compared to... 2 days
At-home biofeedback therapy effective in relieving difficult-to-treat constipation
NEWS MEDICAL Biofeedback therapy used at home is about 70 percent effective at helping patients learn how to coordinate and relax bowel muscles and relieve one of the most difficult-to-treat types of constipation, investigators... 2 days
LYNPARZA Phase III SOLO-1 results show improved outcome for patients with advanced BRCA-mutated ovarian cancer
NEWS MEDICAL AstraZeneca and Merck & Co., Inc., Kenilworth, N.J., (Merck: known as MSD outside the US and Canada) today... 2 days
Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer
NEWS MEDICAL Merck, known as MSD outside the United States and Canada, today announced the first presentation of results from an interim analysis of... 2 days
Vertex gets European CHMP positive opinion for KALYDECO to treat patients with cystic fibrosis
NEWS MEDICAL Vertex Pharmaceuticals (Europe) Limited today announces that the European Medicines Agency's Committee for Medicinal Products for Human Use adopted a... 2 days
Phase III trial reports positive results with HDAC inhibitor in advanced breast cancer patients
NEWS MEDICAL Epigenetic therapy with histone deacetylase inhibitors is worth pursuing in hormone receptor positive advanced breast cancer, suggests a phase III... 2 days
Deciphera presents Phase 1 clinical results of DCC-2618 in patients with gastrointestinal stromal tumors
NEWS MEDICAL Deciphera Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company focused on addressing key mechanisms of tumor drug resistance, announced the presentation today... 2 days
Zoledronic acid increases disease-free survival in premenopausal women with HR+ early breast cancer
NEWS MEDICAL Adjuvant treatment with the bone sparing drug zoledronic acid plus hormonal therapy with the aromatase inhibitor letrozole significantly increases disease-free survival compared... 2 days
Multi-strain probiotic helps reduce chemotherapy-induced diarrhea in cancer patients
NEWS MEDICAL A high concentration of multi-strain probiotic helps to reduce mild to moderate episodes of chemotherapy-induced diarrhea in cancer patients, according to results of a phase II/III study in India. 2 days
Study highlights existence of barriers to early clinical trial access for adolescents and young adults
NEWS MEDICAL Young cancer patients at the crossroads of childhood and adulthood seem to be stuck in a treatment impasse.... 2 days
Immune therapy may be potential treatment option for patients with hard-to-treat ankylosing spondylitis
NEWS MEDICAL Results from a phase 3 clinical trial indicate that patients who have not benefited from standard therapy for ankylosing spondylitis, a chronic... 2 days
Takeda announces positive Phase 3 ALTA-1L data in first-line therapy for advanced ALK+ NSCLC
NEWS MEDICAL Takeda Pharmaceutical Company Limited today announced that intracranial efficacy data from the Phase 3 ALTA-1L (ALK in Lung Cancer Trial... 2 days
ImmunoGen announces study results of platinum-resistant ovarian cancer therapy at ESMO 2018 Congress
NEWS MEDICAL ImmunoGen, Inc., a leader in the expanding field of antibody-drug conjugates for the treatment of cancer, today announced initial safety and preliminary... 2 days
X4 Pharmaceuticals announces clinical data of X4P-001-IO and Opdivo in patients with clear cell renal cell carcinoma
NEWS MEDICAL X4 Pharmaceuticals, a clinical stage biotechnology company developing novel CXCR4 antagonists to improve immune... 2 days
Breast cancer survival could be extended with two new drug combinations
NEWS MEDICAL A new study has shown that a combination of drugs palbociclib, along with hormone therapy can significantly increase the survival among women with advanced breast cancer. 2 days
Radiotherapy can prolong survival in prostate cancer
NEWS MEDICAL A new major study from London has shown that radiotherapy can extend survival among patients with prostate cancer. The study shows that larger number of patients given standard therapy along with radiation therapy survived... 2 days
Roche takes on Loxo, Bayer in gene-defined cancer class
REUTERS Roche's entrectinib cancer pill was shown to shrink tumors in 57 percent of patients within a group that... 3 days
New drug could sustain oxygen-starved hearts
SCIENCE DAILY In new studies, a novel oxygen-delivery therapeutic restored the function of oxygen-starved heart tissue in an animal model of global hypoxia. Unlike its experimental predecessors, the new drug does not appear to cause systemic side effects... 3 days
PTSD symptoms improve when patient chooses form of treatment
SCIENCE DAILY A new study is the first large-scale trial of hundreds of PTSD patients, including veterans and survivors of sexual assault, to measure whether patient preference in the course of treatment... 3 days
Immunotherapy scores a first win against some breast cancers
ABC NEWS A newer immunotherapy drug for the first time has shown promise against breast cancer in a large study that combined it with chemotherapy to treat an aggressive form of the... 3 days
Coming clean: Public embrace for celeb addicts offers hope
ABC NEWS Rehab therapists and addicts in recovery say celebrities who come clean publicly offer hope 3 days
A tailormade drug developed in record time may save girl from fatal brain disease
Science Magazine DNA-based therapy for Batten disease shows promise of personalized medicine 4 days
Making gene therapy delivery safer and more efficient
SCIENCE DAILY Viral vectors used to deliver gene therapies undergo spontaneous changes during manufacturing which affects their structure and function. As gene therapy approaches become more common for treating disease, managing consistency of the... 4 days
Medicating distress: Risky sedative prescriptions for older adults vary widely
SCIENCE DAILY A new study shows wide variation in prescriptions of sedative drugs, called benzodiazepines, to people with Medicare coverage. Some counties, especially in southern and rural western states, had... 4 days
Study points to new method to deliver drugs to the brain
SCIENCE DAILY Researchers have discovered a potentially new approach to deliver therapeutics more effectively to the brain. The research could have implications for the treatment of a wide... 4 days
Medical News Today: Antibiotic resistance: Breakthrough study offers solution
MNT Mice treated with small molecules that stop bacteria forming toxins survived MRSA infection without the need for antibiotics, study found. 4 days
Allergy research: Test predicts outcome of hay fever therapies
SCIENCE DAILY Allergen-specific immunotherapy can considerably improve everyday life for allergy sufferers. It is unclear, however, what exactly happens during this treatment. A team investigated the processes taking place in the body... 4 days
New therapies pack a triple-drug punch to treat cystic fibrosis
SCIENCE-NEWS In testing, a triple-drug therapy significantly improved lung function in cystic fibrosis patients with the most common disease-causing mutation. 4 days
Green Tea Polyphenol Helps Therapeutic RNAs Slip Inside Cells
SCI-NEWS.COM Epigallocatechin gallate (EGCG) is the major polyphenol in the leaves of green tea (Camellia sinensis). This compound is... 4 days
Scientists solve 3-D structure of cystic fibrosis protein in active, inactive states
PHYS.ORG Scientists at the UNC School of Medicine in collaboration with researchers at Oregon Health & Science University have resolved the three-dimensional molecular structure of... 4 days
University of Pittsburgh wins NSF grant for big data research to prevent complications from anesthesia
NEWS MEDICAL The National Science Foundation awarded $1,182,305 to the University of Pittsburgh Swanson School of Engineering to support research... 5 days
Many primary care doctors are still prescribing sedative drugs for older adults
NEWS MEDICAL Despite years of warnings that older adults shouldn't take sedative drugs that put them at risk of injury and death, a new study reveals... 5 days
Understanding of metal-free enzymes used by bacteria could lead to new effective antibiotics
NEWS MEDICAL Some bacterial pathogens, including those that cause strep throat and pneumonia, are able to create the components necessary to replicate their DNA... 5 days
Scientists receive $5.1 million grant to develop stem cell-based therapy for blinding retinal conditions
NEWS MEDICAL Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and the Stein Eye... 5 days
High rate of non-adherence to hormonal therapy found among premenopausal early breast cancer patients
NEWS MEDICAL Nearly one in six premenopausal women being treated for early stage breast cancer do not adhere adequately to tamoxifen therapy... 5 days
Adderall: Uses, Side Effects and Abuse
LIVE SCIENCE Adderall is a prescription medication used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. 5 days
Medical News Today: What are the side effects of insulin therapy?
MNT People with type 1 diabetes need to take insulin to stay healthy. Doctors sometimes also prescribe insulin for people with type 2 diabetes or gestational diabetes.... 5 days
Realizing private and practical pharmacological collaboration
Science Magazine Although combining data from multiple entities could power life-saving breakthroughs, open sharing of pharmacological data is generally not viable because of data privacy and intellectual property concerns. To this end, we leverage modern cryptographic tools to... 5 days
Sharing pharmaceutical research
Science Magazine 5 days
The opium poppy genome and morphinan production
Science Magazine Morphinan-based painkillers are derived from opium poppy (Papaver somniferum L.). We report a draft of the opium poppy genome, with 2.72 gigabases assembled into 11 chromosomes with contig N50 and scaffold N50 of 1.77... 5 days
A revolutionary treatment for allergies to peanuts and other foods is going mainstream—but do the benefits outweigh the risks?
Science Magazine VIDEO Eating small but increasing doses of peanuts seems to protect... 5 days
Medical News Today: High blood pressure control with 'exercise in a pill'
MNT Increased body levels of a compound that the liver makes could control high blood pressure without having to exercise or eat less salt, study... 5 days
Medical News Today: What to know about urine drug screening
MNT Doctors, sports officials, or employers may request a urine drug screen to check if a person has recently used illegal or prescription drugs. Urine tests can detect many... 5 days
Environmental associations with genes may yield opportunities for precision medicine
SCIENCE DAILY A new approach to genetic analysis finds associations between environmental factors and pharmacogenes -- genes associated with a person's response to drugs -- sparking ideas for new research... 5 days
What Caused This Man's Nail to Turn Brown and Striped?
LIVE SCIENCE Chemotherapy can have odd effects on a person's hair and nails, but in one man's case, the cancer treatment created a particularly striking pattern. 5 days
A revolutionary treatment for allergies to peanuts and other foods is going mainstream—but do the benefits outweigh the risks?
Science Magazine
New test rapidly identifies antibiotic-resistant superbugs
PHYS.ORG
Working Towards a Sustainable Future for the NHS
NEWS MEDICAL
Antibody Screening Tools; Improving Workflows
NEWS MEDICAL