Pharmaceuticals
New study reveals yin-yang personality of dopamine  NEWS MEDICAL · 27 minutes
For decades, psychologists have viewed the neurotransmitter dopamine as a double-edged sword: released in the brain as a reward to train us to seek out pleasurable experiences, but also a "drug" the constant pursuit... more
Dermatology providers show interest in recommending cannabinoids to patients  NEWS MEDICAL · 3 hours
The cannabis plant and its derivatives have been used in medicinal treatments for millennia. With the recent legalization of medical marijuana in 33 states across the country, as well as... more
Medical News Today: Single-tablet regimens for HIV  MNT · 8 hours
Following a single-tablet HIV regimen involves taking one pill per day. The pill will contain a combination of two or more antiretroviral drugs. In this article, we look at the benefits of the single-tablet... more
Medical News Today: Can marijuana ease symptoms of Crohn's disease?  MNT · 8 hours
In regions where it is legal, many doctors are prescribing medical marijuana to treat certain conditions. Some small studies suggest that marijuana may also have the potential to... more
Can marijuana ease symptoms of Crohn's disease?  MNT · 8 hours
In regions where it is legal, many doctors are prescribing medical marijuana to treat certain conditions. Some small studies suggest that marijuana may also have the potential to relieve symptoms of Crohn’s disease. However,... more
Why feeling empathy could lead former drug users to relapse  SCIENCE DAILY · 9 hours
Empathy, the awareness of another's feelings and emotions, is a key feature in normal social interactions. But new research suggests that empathy can have detrimental effects on an... more
Research Gaps Leave Doctors Guessing About Treatments For Pregnant Women  NPR · 12 hours
To protect a developing fetus from experimental drugs or treatments that might cause birth defects, pregnant women aren't included in many clinical trials. But that limits the safety... more
Sprayable gel could help the body fight off cancer after surgery  SCIENCE DAILY · 12 hours
A research team has developed a spray gel embedded with immune-boosting drugs that could help lower the risk of cancer recurrence after surgery. more
Providers show interest in prescribing therapeutic cannabinoids  SCIENCE DAILY · 13 hours
Researchers have found many dermatologists are interested in learning more about and recommending therapeutic cannabinoids to their patients. more
Imaging atomic structure of important immune regulator  SCIENCE DAILY · 13 hours
A new study provides a biophysical and structural assessment of a critical immune regulating protein called human T-cell immunoglobulin and mucin domain containing protein-3 (hTIM-3). Understanding the atomic structure of hTIM-3 provides new insights... more
Researchers image atomic structure of important immune regulator  PHYS.ORG · 14 hours
A new study by investigators from Brigham and Women's Hospital provides a biophysical and structural assessment of a critical immune regulating protein called human T-cell immunoglobulin and mucin domain containing protein-3 (hTIM-3).... more
Medical News Today: Future of Alzheimer's therapy: What is the best approach?  MNT · 15 hours
A new comprehensive review assesses current clinical trials for Alzheimer's drugs and advises on the best therapeutic approach going forward. more
Future of Alzheimer's therapy: What is the best approach?  MNT · 16 hours
A new comprehensive review assesses current clinical trials for Alzheimer's drugs and advises on the best therapeutic approach going forward. more
Genetic study of epilepsy points to potential new therapies  SCIENCE DAILY · 16 hours
The largest study of its kind, led by international researchers has discovered 11 new genes associated with epilepsy. It greatly advances knowledge of the underlying biological causes of epilepsy and... more
Romania hospital says 39 babies now diagnosed with superbug  ABC NEWS · 16 hours
Romania hospital says 39 babies now diagnosed with drug-resistant superbug, triple last month more
Using machine learning to design peptides  PHYS.ORG · 17 hours
Scientists and engineers have long been interested in synthesizing peptides—chains of amino acids responsible for conducting many functions within cells—to both mimic nature and to perform new activities. A designed peptide, for example, could be a... more
New optical device brings quantum computing a step closer  PHYS.ORG · 18 hours
An international team of researchers has taken a big step closer to creating an optical quantum computer, which has the potential to engineer new drugs and optimise energy-saving methods. more
Cancer Research UK and AstraZeneca open new Functional Genomics Centre  NEWS MEDICAL · 18 hours
Cancer Research UK and AstraZeneca have announced today (Monday) that they are opening a new center in the UK, dedicated to realizing the full potential of functional genomics... more
Statins have low risk of side effects  SCIENCE DAILY · 19 hours
Cholesterol-lowering statin drugs are associated with a low risk of side effects. The benefits of statin therapy for most people outweigh the risks. more
Statins associated with low risk of side effects  NEWS MEDICAL · 21 hours
The cholesterol-lowering drugs called statins have demonstrated substantial benefits in reducing the risk of heart attacks and strokes caused by blood clots (ischemic strokes) in at-risk patients. more
Novel therapeutic targets based on biology of aging show promise for Alzheimer's disease  NEWS MEDICAL · 1 day
A scientific strategy that explores therapeutic targets based on the biology of aging is gaining ground as an effective approach to prevent... more
Research advances offer hope for patient-tailored AML treatment  NEWS MEDICAL · 1 day
Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia. more
UC San Diego professor receives NCI Outstanding Investigator Award for cancer research  NEWS MEDICAL · 1 day
The National Cancer Institute has awarded David Cheresh, PhD, Distinguished Professor and vice chair of Pathology at University of California San Diego School of... more
International investigators fight against the negative campaign on benzodiazepines  NEWS MEDICAL · 1 day
In the current issue of Psychotherapy and Psychosomaticsthere is news about an international group of investigators who felt that benzodiazepines are getting unwarranted bad press, compared to other psychotropic drugs. more
Ultrarestrictive opioid prescribing strategy linked with reduction in number of pills dispensed  NEWS MEDICAL · 1 day
An ultrarestrictive opioid prescribing strategy was associated with a reduction in the number of pills dispensed in a study of patients having surgery for... more
Potential seen for tailoring treatment for acute myeloid leukemia  SCIENCE DAILY · 3 days
Rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia. Research on the differing drug response patterns of leukemia... more
Medical News Today: Is it possible to reverse 'chemo brain?'  MNT · 3 days
'Chemo brain' affects many people who have undergone cancer treatment. What happens in the brain, and how can we reverse this effect? more
Is it possible to reverse 'chemo brain?'  MNT · 3 days
'Chemo brain' affects many people who have undergone cancer treatment. What happens in the brain, and how can we reverse this effect? more
Study quantifies links between alcohol, drug use and violent deaths  NEWS MEDICAL · 3 days
A group of researchers at the University of São Paulo's Medical School (FM-USP) in Brazil recently published the results of a study on the links between alcohol and... more
Study: Drug reduces hot flash frequency, improves quality of life in breast cancer survivors  NEWS MEDICAL · 3 days
Research led by oncologists Roberto Leon-Ferre, M.D. and Charles Loprinzi, M.D. of Mayo Clinic has found that the drug oxybutynin... more
MIT researchers develop antimicrobial peptides from South American wasp’s venom  NEWS MEDICAL · 3 days
The venom of insects such as wasps and bees is full of compounds that can kill bacteria. Unfortunately, many of these compounds are also toxic for humans, making... more
Silicosis is on the rise, but is there a therapeutic target?  SCIENCE DAILY · 3 days
Researchers have identified a key mechanism of lung inflammation induced by silica exposure, which leads to silicosis, an incurable disease. Their study in mice and patients... more
'Chemo brain' caused by malfunction in three types of brain cells, study finds  SCIENCE DAILY · 3 days
In a new study explaining the cellular mechanisms behind cognitive impairment from chemotherapy, scientists have demonstrated that a widely used chemotherapy drug,... more
Scientists to produce anti-cancer drugs in yeast  SCIENCE DAILY · 3 days
Nature is so complex that natural molecules used for i.e. cancer treatment still can't be produced by chemical synthesis. Today, major chemical and pharmaceutical companies harvest large amounts of rare plants and seeds in... more
Bacterial 'sleeper cells' evade antibiotics and weaken defence against infection  SCIENCE DAILY · 4 days
New research unravels how so-called bacterial persister cells manipulate our immune cells, potentially opening new avenues to finding ways of clearing these bacterial cells from the body, and... more
World's First Insect Vaccine Could Help Bees Fight Off Deadly Disease  NPR · 4 days
American foulbrood is an infectious disease that devastates honeybee hives. Scientists say they've created a vaccine for it, despite a big hurdle: Bees don't have antibodies. more
What can a snowflake teach us about how cancer spreads in the body?  SCIENCE DAILY · 4 days
What can seashells, lightning and the coastline of Britain teach us about new drugs for cancer? The answer, according to a team... more
Double the stress slows down evolution  SCIENCE DAILY · 4 days
Bacteria evolve resistance to antibiotics more slowly if they also have to defend themselves against predators. more
High intensity statin treatment and adherence could save more lives  NEWS MEDICAL · 4 days
Thousands of heart attacks and deaths from cardiovascular disease could be prevented by patients taking higher doses of statins and taking the drugs as advised by doctors. more
Half a million tests and many mosquitoes later, new buzz about a malaria prevention drug  SCIENCE DAILY · 4 days
Researchers spent two years testing chemical compounds for their ability to inhibit the malaria parasite at an earlier... more
Mice display altered immune system following spaceflight  SCIENCE DAILY · 4 days
Based on examinations of mice that had been on board the Bion-M1 biosatellite, new research demonstrates that the outer space environment impairs the production of B lymphocytes, the white blood cells responsible for antibody... more
Engineers repurpose wasp venom as an antibiotic drug  PHYS.ORG · 4 days
The venom of insects such as wasps and bees is full of compounds that can kill bacteria. Unfortunately, many of these compounds are also toxic for humans, making it impossible to use... more
Circulating tumor cell count could help choose treatment for metastatic breast cancer patients  SCIENCE DAILY · 4 days
Circulating tumor-cell (CTC) count could be used to choose hormone therapy or chemotherapy as frontline treatment for patients with estrogen receptor-positive (ER+),... more
Targeted cognitive training benefits patients with severe schizophrenia  SCIENCE DAILY · 4 days
Researchers find that patients with severe, refractory schizophrenia benefit from targeted cognitive therapy, improving auditory and verbal outcomes and the way they process information. more
Eliminating the latent reservoir of HIV  SCIENCE DAILY · 4 days
A new study suggests that a genetic switch that causes latent HIV inside cells to begin to replicate can be manipulated to completely eradicate the virus from the human body. Cells harboring latent HIV are 'invisible'... more
Machine-learning enables a previously-unseen look at polymers helpful in biomedical field  PHYS.ORG · 4 days
Polymers—molecules of repeating chemicals—are the basis of many materials: plastic water bottles, rubber tires, even the keratin in your hair. When certain kinds of polymers are... more
Exercise Can Boost Metabolism, Animal Study Shows  SCI-NEWS.COM · 4 days
A new study shows neurons in mice that influence metabolism are active for up to two days after a single workout. The... more
Bacterial 'sleeper cells' evade antibiotics and weaken defence against infection  PHYS.ORG · 4 days
New research from scientists at Imperial College London unravels how so-called bacterial persister cells manipulate our immune cells. more
MIT engineers repurpose wasp venom as an antibiotic drug  MIT · 4 days
Altered peptides from a South American wasp’s venom can kill bacteria but are nontoxic to human cells. more
Online CBT can help treat gastrointestinal disorders in children  NEWS MEDICAL · 4 days
Cognitive behavioral therapy online can be useful in treating gastrointestinal disorders in children when no physical cause can be found. This is the viewpoint of researchers at Karolinska Institutet in... more
MUHC's 'Dr. House' discovers new genetic disease and the gene responsible for it  NEWS MEDICAL · 4 days
A team from the Research Institute of the McGill University Health Centre led by Dr. Donald Vinh, the RI's so-called "Dr. House"... more
New study shows added benefit of ingenol mebutate for patients with actinic keratosis  NEWS MEDICAL · 4 days
Already in 2013, the German Institute for Quality and Efficiency in Health Care examined in an early benefit assessment whether ingenol mebutate... more
INTEGRA's VIAFLO 96 helps improve reproducibility of high content screening  NEWS MEDICAL · 4 days
INTEGRA’s VIAFLO 96 electronic multi-channel pipetting system is helping biotechnology company HCS Pharma to improve the reproducibility of high content screening using its patented BIOMIMESYS 3D cell culture... more
Type 2 diabetes: A therapeutic avenue is emerging  SCIENCE DAILY · 5 days
Restoring the action of insulin is one of the keys to fighting type 2 diabetes. Researchers are developing a therapeutic strategy that uses the properties of an enzyme (hormone-sensitive lipase) which, when stimulating... more
Surgeon General: Federal drug classification needs changes  ABC NEWS · 5 days
U.S. Surgeon General Jerome Adams has told police officers from across the country that he believes the nation's classification system for illegal drugs should be revisited. more
UMGCCC uses Gammapod radiotherapy to treat breast cancer patients  NEWS MEDICAL · 5 days
Radiation oncologists at the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center are now treating patients with the GammaPod™, a new FDA-cleared radiation therapy for early-stage breast cancer. more
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials  Science Magazine · 5 days
To discover leads for next-generation chemoprotective antimalarial drugs, we tested more than 500,000 compounds for their ability to inhibit liver-stage development of luciferase-expressing Plasmodium spp. parasites (681 compounds showed a... more
Salmonella persisters undermine host immune defenses during antibiotic treatment  Science Magazine · 5 days
Many bacterial infections are hard to treat and tend to relapse, possibly due to the presence of antibiotic-tolerant persisters. In vitro, persister cells appear to be dormant. After uptake of... more
Mice display altered immune system following spaceflight  PHYS.ORG · 5 days
New research published in The FASEB Journal brings to light new information regarding the increased susceptibility of mice to infection during spaceflight. Based on examinations of mice that had been on board the Bion-M1... more
One million mosquitoes and 500,000 tests later, new buzz about a malaria prevention drug  PHYS.ORG · 5 days
Most malaria drugs are designed to reduce symptoms after infection. They work by blocking replication of the disease-causing parasites in... more
Lymph node ratio could predict survival in patients with oral cavity cancer  NEWS MEDICAL · 5 days
Five years after diagnosis, only 40 percent of patients with locally-advanced oral cavity cancer will still be alive. The question is who is likely... more
Medical News Today: Infections and cancer: The link could be stronger than we think  MNT · 5 days
Study reveals a common cellular mechanism through which bacterial infection could promote cancer and increase resistance to anticancer drugs. more
New imaging tools that trace key breast cancer enzymes may help guide therapies  SCIENCE DAILY · 5 days
A set of emerging diagnostic tools may help identify breast cancer patients who are most likely to benefit from therapies that target... more
Statins are recommended far too often, study shows  NEWS MEDICAL · 5 days
Taking cholesterol-lowering drugs, or statins, as a preventive measure can reduce the risk of cardiovascular disease. A study by the University of Zurich now shows that this measure is recommended too often,... more
Researchers use zinc to target insulin-producing cells with regenerative drug  PHYS.ORG · 5 days
An insulin injection can manage diabetes symptoms, but actually curing the disease would mean healing cells in the pancreas that produce insulin, a hormone that regulates the amount... more
Chemists find way to prevent side effects from malaria medication  PHYS.ORG · 5 days
The antimalarial drug Mefloquine, branded as Lariam and used by many travellers to tropical countries, is a substance with two different forms of molecule. One form contains the... more
Researchers identify enzyme responsible for helping cancer tumors spread  PHYS.ORG · 5 days
Researchers at the University of Missouri have unraveled how a cancer-critical enzyme is positioned on cell surfaces. The enzyme enables tumor cells to tunnel through collagen, creating a convenient path... more
New immuno-assay can detect small molecules with 50-fold greater sensitivity  NEWS MEDICAL · 5 days
As medical science has come to understand that the human body is controlled on the molecular level by various proteins, hormones, drugs, and other substances, technologies have developed... more
Liraglutide drug associated with lower risk of cardiovascular events  NEWS MEDICAL · 5 days
Real world data from a large Nordic study shows that use of liraglutide, a drug for type 2 diabetes, is associated with a lower risk of myocardial infarction, stroke or... more
Study: Chemotherapy agent did not improve survival in patients with triple-negative breast cancer  NEWS MEDICAL · 5 days
Treating patients who had early-stage triple-negative breast cancer with the chemotherapy agent capecitabine after they completed surgery and standard chemotherapy did not... more
Common antidepressant does not promote recovery after stroke, study finds  NEWS MEDICAL · 5 days
Stroke patients prescribed a common antidepressant show no improvement compared with those given a dummy drug, a study has found. more
Optimization of drug dose sizes can reduce pharmaceutical wastage  NEWS MEDICAL · 5 days
Pharmaceuticals are often dosed according to patient weight or body size which means that a dose must be individually measured. In a new study, lead author Anthony Hatswell of Delta... more
Scientists identify new drug target for potential blood pressure treatment  NEWS MEDICAL · 5 days
Scientists have identified a key player in blood pressure regulation and have shown that switching it off reduces blood pressure in mice, according to new research in eLife. more
New therapeutic strategy is emerging for type 2 diabetes  NEWS MEDICAL · 5 days
Diabetes is a disease in which blood sugar levels are high over a prolonged period (hyperglycemia). In the case of type 2 diabetes, this phenomenon which is caused by a... more
Study finds increasing risk of infections and antibiotic prescriptions after hip fracture surgery  NEWS MEDICAL · 5 days
In a Journal of Bone and Mineral Research study that examined trends in the incidence of infections following hip fracture surgery in... more
Memory B cells in the lung may be important for more effective influenza vaccinations  SCIENCE DAILY · 5 days
Using a mouse model of influenza and experiments that included parabiosis, researchers definitively showed that lung-resident memory B cells establish... more
Medical News Today: What to know about HAART for HIV  MNT · 5 days
HAART refers to any treatment for HIV that uses two or more antiretroviral drugs. Also called combined antiretroviral therapy, this regimen revolutionized HIV treatment in 1996, making it... more
Medical News Today: What is a 4th generation HIV test?  MNT · 5 days
Fourth-generation HIV tests can detect both HIV antibodies and p24 antigens, while the older tests can only check for antibodies. This means that the newer tests can identify... more
Medical News Today: HIV and hair loss: What's the link?  MNT · 5 days
While older HIV drugs may have caused hair loss, this is unlikely with modern medicines. In this article, learn more about the possible links between HIV and hair... more
New immunoassay technique measures extremely low concentrations of small molecules using single-molecule detection  PHYS.ORG · 5 days
As medical science has come to understand that the human body is controlled on the molecular level by various proteins, hormones, drugs,... more
[Research Articles] Noninvasive 11C-rifampin positron emission tomography reveals drug biodistribution in tuberculous meningitis  Science Magazine · 6 days
Tuberculous meningitis (TBM) is a devastating form of tuberculosis (TB), and key TB antimicrobials, including rifampin, have restricted brain penetration. A lack... more
Distinguishing resistance from resilience to prolong antibiotic potency  PHYS.ORG · 6 days
Biomedical engineers at Duke University have shown experimentally that there is more than one flavor of antibiotic resistance and that it could—and should—be taken advantage of to keep first-line antibiotics in our... more
Applying ecological resistance and resilience to dissect bacterial antibiotic responses  Science Magazine · 6 days
An essential property of microbial communities is the ability to survive a disturbance. Survival can be achieved through resistance, the ability to absorb effects of a disturbance without... more
A banner year for pharma  PHYS.ORG · 6 days
As 2018 draws to a close, the pharmaceutical industry is celebrating a prosperous year of new investments and therapeutic breakthroughs. These successes were driven by cutting-edge science and progress in finally translating long-standing technology into actual products, according... more
New study sheds light on medication administration errors leading to death -- omission is a common cause  SCIENCE DAILY · 6 days
Medication administration errors leading to death are common with anticoagulants and antibiotics in particular,... more
Medical News Today: What role do brain lipids play in Parkinson's disease?  MNT · 6 days
Researchers studying the connection between lipids and toxic protein levels have uncovered a new potential therapeutic target for Parkinson's disease. more
What role do brain lipids play in Parkinson's disease?  MNT · 6 days
Researchers studying the connection between lipids and toxic protein levels have uncovered a new potential therapeutic target for Parkinson's disease. more
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