Pharmaceuticals
UTSW/Children's Health joint program approved as Certified Duchenne Care Center  NEWS MEDICAL · 30 minutes
A joint program of UT Southwestern Medical Center and Children's Health has been approved as a Certified Duchenne Care Center by Parent Project Muscular Dystrophy, the nation's most... more
USAMRDC receives FDA marketing approval for severe malaria treatment  NEWS MEDICAL · 1 hour
The U.S. Army Medical Research and Development Command announced today that the U.S. Food and Drug Administration granted marketing approval for Artesunate for Injection, an initial treatment for severe malaria. more
How do we disconnect from the environment during sleep and under anesthesia?  SCIENCE DAILY · 4 hours
A series of new studies finds, among other important discoveries, that noradrenaline, a neurotransmitter secreted in response to stress, lies at the heart of... more
Can plasma from COVID-19 survivors help save others?  Science Magazine · 5 hours
Small studies suggest transfusions with antibody-laden blood plasma may help patients fight the virus more
Nimodipine-loaded biodegradable fibers to protect nerve cells after brain surgery  NEWS MEDICAL · 7 hours
Brain surgery poses a major threat to nerve cells. Even slight injuries can kill the sensitive cells. The drug nimodipine could help prevent this. more
Clinical trial advances treatment for multiple sclerosis  NEWS MEDICAL · 8 hours
Researchers conducting a clinical trial to advance the treatment of multiple sclerosis successfully applied a new drug testing methodology which allows several treatment options to be trialled at once. more
More effective human antibodies possible with chicken cells  SCIENCE DAILY · 8 hours
Antibodies for potential use as medicines can be made rapidly in chicken cells grown in laboratories. Researchers refer to their technique as the human ADLib system, short for autonomously diversifying libraries. The... more
Taking inventory of which drugs the world is using to treat COVID-19  SCIENCE DAILY · 9 hours
New research catalogued every COVID treatment documented in medical literature so far and found physicians have reported on the use of more than 100... more
Target trials provide an ethical way to collect drug exposure data for pregnant people  NEWS MEDICAL · 9 hours
Out of concern for fetal safety, pregnant people have typically been excluded from drug trials. And when human health is... more
Scientists discover two anti-inflammatory drugs that inhibit COVID-19 infection  NEWS MEDICAL · 9 hours
Since the outbreak of the COVID-19 pandemic and its rapid spread, the scientific community has been working on developing an effective treatment for the virus responsible for the disease. more
Structural basis of broad HIV neutralization by a vaccine-induced cow antibody  Science Magazine · 9 hours
Potent broadly neutralizing antibodies (bnAbs) to HIV have been very challenging to elicit by vaccination in wild-type animals. Here, by x-ray crystallography, cryo–electron microscopy, and site-directed... more
Feature-rich covalent stains for super-resolution and cleared tissue fluorescence microscopy  Science Magazine · 9 hours
Fluorescence microscopy is a workhorse tool in biomedical imaging but often poses substantial challenges to practitioners in achieving bright or uniform labeling. In addition, while antibodies are effective... more
Monocyte-derived multipotent cell delivered programmed therapeutics to reverse idiopathic pulmonary fibrosis  Science Magazine · 9 hours
Idiopathic pulmonary fibrosis (IPF) is a highly heterogeneous and fatal disease. However, IPF treatment has been limited by the low drug delivery efficiency to lungs and... more
Platelet-derived porous nanomotor for thrombus therapy  Science Magazine · 9 hours
The treatment difficulties of venous thrombosis include short half-life, low utilization, and poor penetration of drugs at thrombus site. Here, we develop one kind of mesoporous/macroporous silica/platinum nanomotors with platelet membrane (PM) modification (MMNM/PM) for sequentially... more
Ivy Center opens new clinical trial to evaluate experimental drug cocktail for glioblastoma  NEWS MEDICAL · 10 hours
The Ivy Brain Tumor Center at Barrow Neurological Institute announced that patient recruitment has opened for a new Phase 0 clinical trial... more
Extraction of skin interstitial fluid using microneedle patches  PHYS.ORG · 10 hours
Interstitial fluid is a major component of the liquid environment in the body and fills the spaces between the body's cells. In contrast, blood circulates only within the circulatory vessels of the... more
No-deductible preventive drugs can reduce out-of-pocket costs for diabetic patients  NEWS MEDICAL · 11 hours
For patients with diabetes - especially those with lower incomes - preventive drug lists (PDLs) of essential medications available with no deductible can reduce out-of-pocket costs while increasing... more
Researchers are taking inventory of drugs used to treat COVID-19  NEWS MEDICAL · 11 hours
With doctors and researchers around the world searching for effective treatments for COVID-19, many drugs approved to treat other diseases are being used in hopes that they'll be... more
Researchers are taking inventory of drugs used to treat the COVID-19 pandemic  NEWS MEDICAL · 11 hours
With doctors and researchers around the world searching for effective treatments for COVID-19, many drugs approved to treat other diseases are being used in... more
A new therapeutic approach to improve the health of diabetic patients  NEWS MEDICAL · 12 hours
Scientists at Sanford Burnham Prebys Medical Discovery Institute have mapped for the first time the vast network of proteins that interact with proinsulin, the protein the... more
How often do vaccine trials hit paydirt?  MIT · 13 hours
Study: Vaccines find more success in development than any other kind of drug, but have been relatively neglected in recent decades. more
Medicinal chemistry breakthrough could lead to better pharmaceuticals  PHYS.ORG · 14 hours
Medications are developed to work well for most people, but those whose genetic makeup causes them to metabolize medicine too quickly often need higher doses of the drugs they take in order... more
Supercomputing aids scientists seeking therapies for deadly bacterial disease  PHYS.ORG · 14 hours
Francisella tularensis, a bacterium that causes the illness tularemia (also known as "rabbit fever"), is one of the most hostile organisms on the planet. Once the bacterium enters the body... more
Researchers trigger enzymes with light  PHYS.ORG · 14 hours
Enzymes are the central drivers for biochemical metabolic processes in every living cell, enabling reactions to take place efficiently. It is this ability that makes them useful as catalysts in biotechnology, for example, to create chemical products such... more
New book series brings updated reviews on diabetes and obesity  NEWS MEDICAL · 20 hours
Frontiers in Clinical Drug Research - Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents... more
Doxycycline is not effective in reducing the growth of abdominal aortic aneurysm  NEWS MEDICAL · 20 hours
A new landmark study by researchers at the University of Maryland School of Medicine (UMSOM) found that patients with a vascular condition, called an... more
Updates on stem cell therapeutics and regenerative medicine  NEWS MEDICAL · 21 hours
Stem cell and regenerative medicine research is an important area of clinical research which promises to change the face of medicine as it will be practiced in the years to come. more
Study finds very low level of SARS-CoV-2 in two San Francisco Bay areas  NEWS MEDICAL · 24 hours
A new study published on the preprint server medRxiv in May 2020 reports a very low prevalence of antibodies in two separate... more
Majority of people in Vancouver’s Downtown Eastside use cannabis for therapeutic reasons  NEWS MEDICAL · 1 day
Most people at high risk of overdose in Vancouver's Downtown Eastside who use cannabis do so for pain relief and other therapeutic reasons--and they... more
Study shows antihypertensive drugs do not raise serum levels of ACE2  NEWS MEDICAL · 1 day
A new study published on the preprint server medRxiv* by researchers from Iceland and the U.S. shows how treatment with angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin... more
IgG antibodies reduce viral load of SARS-CoV-2  NEWS MEDICAL · 1 day
A study conducted by researchers at the University of Washington has highlighted the importance of serological testing for infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). more
Montefiore and Einstein evaluate a new drug combination to fight COVID-19  NEWS MEDICAL · 1 day
Montefiore Health System Albert Einstein College of Medicine have begun the next stage of the Adaptive COVID-19 Treatment Trial (ACTT), to evaluate treatment options for people... more
New drug combination being tested to conquer COVID-19  SCIENCE DAILY · 1 day
Researchers hope giving Remdesivir along with a powerful anti-inflammatory could be the key to treating the most severe COVID-19 cases. more
Antimalarial drug shows promise as potential therapy for aggressive brain cancer  NEWS MEDICAL · 1 day
Glioblastoma multiforme is an aggressive form of cancer in the brain that is typically fatal. But new findings by VCU Massey Cancer Center and VCU Institute... more
Triggered by light, a novel way to switch on an enzyme  SCIENCE DAILY · 1 day
In living cells, enzymes drive biochemical metabolic processes. It is this very ability which allows them to be used as catalysts in biotechnology, for example to... more
Pharmacist, used car salesman charged with COVID-19 fraud  ABC NEWS · 1 day
A pharmacist and a used car salesman have been arrested on charges that they designed frauds to capitalize on the search for protective equipment during the pandemic more
New approach to some mental disorders  SCIENCE DAILY · 1 day
Depression, anxiety and PTSD might not be disorders at all, according to biological anthropologists. In the paper, the researchers propose a new approach to mental illness that would be informed by human evolution, noting that modern... more
Finding unique drug structures with artificial intelligence and chemistry  PHYS.ORG · 1 day
In the search for new medicines against diseases such as cancer, a Leiden team has developed a new workflow. This approach combines artificial intelligence (AI) with molecular modelling and is... more
The Latest: Italy's Red Cross calling for antibody tests  ABC NEWS · 1 day
Italy’s health minister is appealing to citizens to answer the Red Cross call for a blood test to determine if they have antibodies to COVID-19 more
New technique for fast, easy optimization of antibodies using chicken cells  NEWS MEDICAL · 1 day
Antibodies for potential use as medicines can be made rapidly in chicken cells grown in laboratories. Researchers refer to their technique as the human ADLib system,... more
Most Medicare enrollees could get insulin for $35 a month  ABC NEWS · 1 day
The Trump administration says most people with Medicare will have access to prescription plans next year that limit their copays for insulin to a maximum of $35 a... more
Researchers develop the 'ultimate cell sorter'  PHYS.ORG · 2 days
In medicine and biology, there is great interest in efficient and inexpensive methods for identifying and separating different cell types, for example for medical diagnostics or for regenerative therapies using stem cells. Up to this point,... more
The Latest: British agency allows experimental virus drug  ABC NEWS · 2 days
Britain’s medicines agency has authorized the use of the experimental drug remdesivir for COVID-19 patients more
Bioelectric drugs can help repair defects in developing frog brain  NEWS MEDICAL · 2 days
Researchers led by biologists at Tufts University have discovered that the brains of developing frog embryos damaged by nicotine exposure can be repaired by treatment with certain drugs... more
New design strategy marks a potential advance in the fight against Alzheimer's disease  NEWS MEDICAL · 2 days
Researchers have found a way to design an antibody that can identify the toxic particles that destroy healthy brain cells - a... more
Zero benefit of Hydroxychloroquine or Chloroquine in COVID-19, says extensive study  NEWS MEDICAL · 2 days
The purported "game-changer" anti-malarial drug Hydroxychloroquine, which was claimed to be effective in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and also helping better... more
New study pinpoints ideal antiviral targets within the SARS-CoV-2 viral cycle  NEWS MEDICAL · 2 days
A specific biophysical model for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shows how potential drugs inhibiting both viral transcription and translation would be particularly effective... more
WHO Halts Hydroxychloroquine Trial Over Safety Concerns  NPR · 2 days
The WHO cited a scientific study published last week suggesting that proposed COVID-19 drug hydroxychloroqine may do more harm than good in halting its study to review data. more
UN virus therapy trial pauses hydroxychloroquine testing  ABC NEWS · 2 days
The World Health Organization says it will temporarily drop hydroxychloroquine from its global study into experimental COVID-19 treatments because its experts need to review all available evidence more
New therapeutic approach for aggressive breast cancer  NEWS MEDICAL · 2 days
This type of TNBC tumor does not express any of the receptors involved in most breast cancers (estrogen, progesterone and HER2), so the most common treatments, such as the hormone therapy, are not viable... more
Can Chlorpromazine help treat COVID-19?  NEWS MEDICAL · 3 days
A new research paper published in the journal L'Encéphale in May 2020 reports on the planned ReCoVery Study, which will examine the possibility of repurposing the antipsychotic drug chlorpromazine for the treatment of COVID-19. more
The Latest: France health minister: Limits on malaria drug  ABC NEWS · 5 days
France’s health minister wants to limit use of a malaria drug as a coronavirus treatment after a new study found it ineffective and warned of increased health risks more
Study brings surgeons one step closer to helping babies with Hirschsprung's disease  NEWS MEDICAL · 5 days
Babies with Hirschsprung's disease are born with an incomplete or absent gut nervous system. Children's Hospital Los Angeles investigator Tracy Grikscheit, MD, runs a... more
Scientists identify chemicals in noxious weed that 'disarm' deadly bacteria  SCIENCE DAILY · 5 days
Scientists have identified specific compounds from the Brazilian peppertree -- a weedy, invasive shrub in Florida -- that reduce the virulence of antibiotic-resistant staph bacteria. This research demonstrates... more
A 'switch' that turns autoimmunity drugs into powerful anti-cancer treatments  SCIENCE DAILY · 5 days
Scientists have discovered a way to transform antibody drugs previously developed to treat autoimmunity into antibodies with powerful anti-cancer activity through a simple molecular 'switch'. more
The self-synthesizing ribosome  SCIENCE DAILY · 5 days
As the cell's protein factory, the ribosome is the only natural machine that manufactures its own parts. That is why understanding how the machine, itself, is made, could unlock the door to everything from understanding how life develops to designing... more
Self-healing microcapsules synergetically modulate immunization microenvironments for potent cancer vaccination  Science Magazine · 5 days
Therapeutic cancer vaccines that harness the immune system to reject cancer cells have shown great promise for cancer treatment. Although a wave of efforts have spurred to improve... more
Big study casts more doubt on malaria drugs for coronavirus  ABC NEWS · 5 days
A large new study suggests that malaria drugs pushed by President Donald Trump as treatments for the coronavirus not only do not help but also are tied to... more
First human trial of COVID-19 vaccine finds it is safe and induces rapid immune response  SCIENCE DAILY · 5 days
A study of 108 adults finds that the vaccine produced neutralizing antibodies and T-cell response against SARS-CoV-2, but... more
No evidence of benefit for chloroquine and hydroxychloroquine in COVID-19 patients, study finds  SCIENCE DAILY · 5 days
A new study finds that the use of chloroquine or hydroxychloroquine is linked to increased rates of mortality and heart arrhythmias among... more
Study reveals mechanism involved in the development of diabetes, fatty liver  NEWS MEDICAL · 5 days
A research group including Professor OGAWA Wataru (Division of Diabetes and Endocrinology, Kobe University Graduate School of Medicine) and Project Associate Professor HOSOOKA Tetsuya (Division of... more
New technology can detect antivirus antibody in 20 minutes  PHYS.ORG · 6 days
Researchers have succeeded in detecting anti-avian influenza virus antibody in blood serum within 20 minutes, using a portable analyzer they have developed to conduct rapid on-site bio tests. If a... more
Portable analyzer rapidly detects anti-virus antibody in blood serum  NEWS MEDICAL · 6 days
Researchers have succeeded in detecting anti-avian influenza virus antibody in blood serum within 20 minutes, using a portable analyzer they have developed to conduct rapid on-site bio tests. If a... more
Study reveals the mechanism involved in the development of diabetes, fatty liver  NEWS MEDICAL · 6 days
A research group including Professor OGAWA Wataru (Division of Diabetes and Endocrinology, Kobe University Graduate School of Medicine) and Project Associate Professor HOSOOKA Tetsuya... more
Brain's 'updating mechanisms' may create false memories  SCIENCE DAILY · 6 days
New research is one of the first comprehensive characterizations of poorly formed memories and may offer a framework to explore different therapeutic approaches to fear, memory and anxiety disorders. It may also have implications... more
Cockle shells picked to treat dog cancer  PHYS.ORG · 6 days
The calcium mineral from which many shellfish, such as cockles, make their shells can be used to form nanoparticles. These nanoparticles can then be "loaded" with small drug molecules, such as anticancer drugs. more
Understanding the atomic details of the endoplasmic reticulum membrane protein complex  PHYS.ORG · 6 days
All human cells are enclosed in a greasy membrane that is embedded with thousands of different proteins. These so-called membrane proteins carry out countless functions, from... more
The Latest: Italian agency warns of anti-malaria drug use  ABC NEWS · 6 days
The head of Italy’s pharmacological agency says there is little data about the effectiveness of the anti-malaria drug promoted by U.S. President Donald Trump to treat coronavirus more
Setting up & executing liquid handling protocols remotely  NEWS MEDICAL · 6 days
COVID-19 is requiring us to work differently. Research teams have had to work virtually whilst accelerating the delivery of life saving diagnostics and therapeutics. more
Scientists identify compounds in noxious weed that reduce virulence of Staphylococcus bacteria  NEWS MEDICAL · 6 days
Scientists have identified specific compounds from the Brazilian Peppertree -- a weedy, invasive shrub in Florida -- that reduce the virulence of antibiotic-resistant staph... more
Changes in antibodies and RNA shedding during early SARS-CoV-2 infection  NEWS MEDICAL · 6 days
As the COVID-19 pandemic and its far-reaching implications continue to unfold globally and disrupt our normal way of life, scientists and researchers are racing to find an appropriate... more
GlobalData: Patients treated for ICU delirium will increase as COVID-19 outbreak continues  NEWS MEDICAL · 6 days
An estimated 70–80% of ventilated patients will experience ICU delirium, which causes patients to enter a confused state and can lead to long-term cognitive... more
IL-6 blocker use in severe COVID-19 increases risk of secondary infections  NEWS MEDICAL · 6 days
With many hundreds of thousands of deaths due to the current COVID-19 pandemic, there is a rush to find an effective vaccine or drug against the... more
Study evaluates the effectiveness of interferon beta 1b in COVID-19 pneumonia  NEWS MEDICAL · 6 days
As the world struggles to overcome the current COVID-19 pandemic with non-pharmacological interventions, in the absence of an effective drug or vaccine, existing immunomodulators are being... more
Preparing to meet SARS-CoV-2 head-on with a panel of neutralizing antibodies  NEWS MEDICAL · 6 days
A new study published on the preprint server bioRxiv in May 2020 describes a panel of neutralizing antibodies that bind to multiple attachment sites on the... more
Simple molecular 'switch' transforms autoimmunity drugs into powerful anti-cancer treatments  NEWS MEDICAL · 6 days
Scientists from the Antibody and Vaccine group at the University of Southampton have discovered a way to transform antibody drugs previously developed to treat autoimmunity into antibodies with... more
ELISA and CLIA antibody tests for SARS-CoV-2 perform best in terms of sensitivity  NEWS MEDICAL · 6 days
Testing for those who have developed antibodies against the coronavirus can help tackle the ongoing COVID-19 pandemic. Now, a new study has... more
Airway and Celonic collaborate to produce AT-100 as therapeutic candidate against COVID-19  NEWS MEDICAL · 6 days
Airway Therapeutics, Inc., a biopharmaceutical company developing a new class of biologics to break the cycle of injury and inflammation for patients with respiratory... more
UEA research recommends changes to prevent controversial pharmaceutical deals  NEWS MEDICAL · 6 days
New research from the University of East Anglia (UEA) recommends changes to the system which sees drug companies strike deals with competitors to stop them producing cheaper generic alternatives. more
Study shows selenium-containing compounds inhibit SARS-CoV-2 replication and assembly  NEWS MEDICAL · 6 days
A recent paper by researchers from the Netherlands and Poland provides evidence that modified ebselen derivatives may serve as highly promising prospective drugs against coronavirus disease 2019 (COVID-19). The manuscript... more
Preventing 'cytokine storm' may ease severe COVID-19 symptoms  SCIENCE DAILY · 6 days
A clinical trial in people with the new coronavirus is testing a drug that may halt an overactive immune response before it ramps up. more
US begins crackdown on unvetted virus blood tests  ABC NEWS · 6 days
The U.S. Food and Drug Administration is moving ahead with a crackdown on scores of COVID-19 antibody tests that have not yet been shown to work more
Drug combination could eliminate side effects of once-popular diabetes treatment  SCIENCE DAILY · 6 days
A new study shows how an effective but largely abandoned treatment for Type 2 diabetes could be used again in combination with another drug to eliminate problematic side... more
Heating poppy seeds, but not baking them in muffins, reduces opiate levels  SCIENCE DAILY · 6 days
You might have heard the advice to avoid eating a poppy seed bagel or muffin before a drug screen, lest you test positive for... more
Biophysicists find a way to take a peek at how membrane receptors work  PHYS.ORG · 6 days
In a study published in Current Opinion in Structural Biology, MIPT biophysicists explained ways to visualize membrane receptors in their different states.... more
Cell-culture based in vitro test systems for antitumor drug screening  NEWS MEDICAL · 6 days
As we know, a malignant tumor is a complex system of mutated cells which constantly interacts with and involves healthy cells in the body. more
Research demonstrates self-synthesis and assembly of 30S subunit of ribosome  NEWS MEDICAL · 6 days
As the cell's protein factory, the ribosome is the only natural machine that manufactures its own parts. That is why understanding how the machine, itself, is made, could... more
The self-synthesizing ribosome  PHYS.ORG · 7 days
As the cell's protein factory, the ribosome is the only natural machine that manufactures its own parts. That is why understanding how the machine, itself, is made, could unlock the door to everything from understanding how life develops to designing... more
Life, death, and the litter layer: The war on drugs in the Amazon rainforest  PHYS.ORG · 7 days
The canopy is thick, the air heavy. The Amazon rainforest pulsates with life, sustaining an estimated 10 million species on... more
Quantum leap: Photon discovery is a major step toward at-scale quantum technologies  SCIENCE DAILY · 7 days
A team of physicists has developed the first integrated photon source with the potential to deliver large-scale quantum photonics. The development of quantum technologies... more
Comprehensive review of clioquinol drug gives valuable insights  NEWS MEDICAL · 7 days
CQ is an old drug that was commonly used to treat fungal/protozoal infections of the gastrointestinal tract. Patients in Japan taking it developed subacute myelo-optic neuropathy which resulted in CQ being discontinued... more
Producing Virus-Specific Antibodies after COVID-19  NEWS MEDICAL · 7 days
In order to design effective vaccines for COVID-19, we need to understand our immune responses. News-Medical speaks to Professor Chen Dong to find out more. more
MORE SCIENCE VIDEO
Can Chlorpromazine help treat COVID-19?
NEWS MEDICAL
Doomsday prepping in the age of coronavirus
PHYS.ORG
FRESH SCIENCE