Researchers have discovered a scorpion toxin that targets the 'wasabi receptor,' a chemical-sensing protein found in nerve cells that's responsible for the... more
Surgeons wielding their life-saving scalpels, laparoscopic tools, or other implements to repair or remove what ails their patients understand all too well that pain is an unavoidable part of the... more
Surgeons wielding their life-saving scalpels, laparoscopic tools, or other implements to repair or remove what ails their patients understand all too well that pain is an unavoidable part of the... more
Using the largest database of real-time recordings of the effects of common and commercially available cannabis products in the United States, researchers at The University of... more
While typical treatment for endometriosis includes surgery, hormone therapy, and pain medications, some people also use essential oils. Learn whether they are effective here. more
A recent study found that people with chronic lower back pain who performed self-administered acupressure experienced improvement in pain and fatigue symptoms. more
Using the largest database of real-time recordings of the effects of common and commercially available cannabis products in the United States, researchers found strong evidence that cannabis can... more
An integrated approach that unifies psychosocial factors with neurobiology sheds light on chronic pain traits and their underlying brain networks, according to a study published August 20 in the open-access... more
There are many possible causes of eyebrow pain, including sinusitis, headaches, shingles, and glaucoma. Learn about these and other causes, as well as how to get relief, here. more
From tea bags to cold compresses, many home remedies can quickly relieve mild-to-moderate gum pain. Learn about these methods, and when to see a dentist, here. more
An integrated approach that unifies psychosocial factors with neurobiology sheds light on chronic pain traits and their underlying brain networks, according to a new study. more
Neuropathic pain is a chronic condition resulting from nerve injury and is characterized by increased pain sensitivity. Although known to be associated with overly excitable neurons in the spinal cord, the mechanisms... more
Osteopathic medicine's emphasis on physician empathy and understanding leads to higher patient satisfaction, a study by researchers at UNTHSC's Texas College of... more
Neuropathic pain affects between 15 and 20 million people in the U.S. This type of pain can occur after injuries to the nervous system due to trauma, disease... more
A team at Scripps Research in Florida has discovered a biological system that manages cells' response to opioid drug exposure. The unexpected discovery offers... more
Researchers have discovered a new sensory organ located underneath the skin. The discovery could lead to the development of new, more effective pain killers. more
A recent study found virtual reality experiences were better at easing pain than watching televised nature scenes. Immersive distraction seems key to the success,... more
A team has discovered a biological system that manages cells' response to opioid drug exposure. The unexpected discovery offers new ideas for improving the... more
Therapeutic virtual reality can be used to reduce severe pain in hospitalized patients, according to a study published August 14, 2019 in the open-access journal PLOS... more
An essential prerequisite for the survival of an organism is the ability to detect and respond to aversive stimuli. Current belief is that noxious stimuli directly activate nociceptive sensory nerve endings in the skin.... more
Opioids target the μ-opioid receptor (MOR) to produce unrivaled pain management but their addictive properties can lead to severe abuse. We developed a whole animal behavioral platform for unbiased discovery of genes... more
For children and teens with migraine, the pain and symptoms that accompany migraine attacks can be debilitating, resulting in missed school days, absence from social or sporting events, and affected... more
When they started practicing medicine, most surgeons say, there was little or no information about just how many pain pills patients needed after specific... more
For children and teens with migraine, the pain and symptoms that accompany migraine attacks can be debilitating, resulting in missed school days, absence from... more
A team at the University of Cambridge has shown how, in osteoarthritis patients, the viscous lubricant that ordinarily allows our joints to move smoothly... more
A team has shown how, in osteoarthritis patients, the viscous lubricant that ordinarily allows our joints to move smoothly triggers a pain response from nerve cells... more
A new study shows how one state's surgeons reduced the number of opioids they prescribed to thousands of patients -- without causing patients to feel more... more
The pain-relieving effect of salicylic acid, now sold as Aspirin, has been known for thousands of years. Besides being a useful drug with numerous health applications, it is a stress hormone made by plants which is essential in... more
Opioid misuse has become a significant public health problem. Despite efforts to control its use, opioid is still the most widely prescribed class of medicines. Now, a new... more
The pain-relieving effect of salicylic acid has been known for thousands of years. Besides being a useful drug with numerous health applications, it is a stress hormone made by plants, which is essential for them to fight off... more
A researcher from the University of Houston has found that adults who take prescription opioids for severe pain are more likely to have increased anxiety, depression... more
Not a good mix: A researcher has found that adults who combine prescription opioids for severe pain and cannabis report elevated anxiety and depression... more
A new study takes a harder look at the effects a common anti-inflammatory medication and its degradation products have on amphibians. There have been many studies that review the toxicity of naproxen, a common over-the-counter pain... more
A new study in Environmental Toxicology and Chemistry takes a harder look at the effects a common anti-inflammatory medication and its degradation products have on amphibians. There have been many studies that review the toxicity of... more
Researchers have developed a soft neural implant that can be wirelessly controlled using a smartphone. It is the first wireless neural device capable of indefinitely delivering... more
A wide variety of conditions can cause periumbilical pain, making it difficult for doctors to diagnose. Learn about the causes and treatment options here. more
A wide variety of conditions can cause periumbilical pain, making it difficult for doctors to diagnose. Learn about the causes and treatment options here. more
Neuroscientists have developed a method that can more accurately gauge pain in mice, which could lead researchers to discover new ways to treat pain in human patients. more
Scientists will develop technologies within the new SHERO project that allow soft robots to self-heal damage. Because this repair process should not involve humans, the researchers are looking into self-healing... more
For decades, biomedical researchers have used mouse behavior to study pain, but some researchers have questioned the accuracy of the interpretations of how mice experience pain. more
Opioid use at the three-month follow-up in emergency department patients discharged with an opioid prescription for acute pain is relatively low and not necessarily... more
Patients fitted with an orthopedic prosthetic commonly experience a period of intense pain after surgery. In an effort to control the pain, surgeons inject painkillers into the tissue during the... more
Patients fitted with an orthopedic prosthetic commonly experience a period of intense pain after surgery. In an effort to control the pain, surgeons inject painkillers into the tissue... more
Nonsteroidal anti-inflammatory drugs (NSAIDs) can help to control the pain and inflammation in individuals with osteoarthritis, but a new Arthritis & Rheumatology study suggests that NSAIDs contribute to... more
Tonsillitis is a viral or bacterial infection that causes swelling and pain in and around the tonsils. Learn about a variety of home remedies for tonsillitis in this... more
Neurological diseases like Alzheimer’s disease, Parkinson’s disease, depression, pain disorders and addictions could now be treated from within the brain itself using an intriguing new soft implant in the brain itself. more
Researchers have developed a soft neural implant capable of delivering multiple drugs and colour lights which neuroscientists believe can speed up efforts to uncover brain diseases such as Parkinson's, Alzheimer's, addiction, depression,... more
A team of scientists have invented a device that can control neural circuits using a tiny brain implant controlled by a smartphone. The device could speed up efforts to uncover brain diseases... more
An interdisciplinary team in San Francisco uses acupressure, massage, counseling and other methods, as well as medicine, to help kids get relief from chronic pain. But... more
Opioids are among the most effective pain relievers in dogs and cats, but amid the U.S. opioid crisis it has become much more difficult for animal hospitals to access these drugs. This,... more
A pulled stomach muscle or a strain can cause pain and tenderness. Learn about the causes, such as exercise and overuse, as well as other possible abdominal injuries here. more
Pain in the lower left back often originates from muscle strains or kidney problems, but there are many other possible causes. We describe these causes and... more
Imagine if food caused pain... nausea… reflux… was hard to swallow or even suddenly became stuck in your esophagus. That can be the reality for someone living with an eosinophilic... more
A heatwave that smashed temperature records in northern Europe finally relented Friday but thousands of holidaymakers were snared in travel chaos that followed the hot weather. more
Windburn can occur when the skin gets exposure to harsh winds and cold conditions. It often causes redness and pain. Remedies include rehydrating and using moisturizer. Learn more here. more
The right upper quadrant of the abdomen includes the pancreas, right kidney, gallbladder, liver, and intestines. Pain under the ribs in this area can indicate an... more
A surprising new discovery in mouse models reveals a previously unknown role for pain in immunity and has implications for treating autoimmune diseases. more
The cannabis plant produces pain-relieving molecules that are 30x more effective than aspirin. Researchers are now working on a plant-based pain killer. more
Cuts, scrapes, blisters, burns, splinters, and punctures - there are a number of ways our skin can be broken. Most treatments for skin wounds involve simply placing a barrier over them (usually an adhesive... more
Kava (Piper methysticum) is a plant native to the Polynesian islands that people there have used in a calming drink of the same name in religious and cultural... more
University of Guelph researchers are the first to uncover how the cannabis plant creates important pain-relieving molecules that are 30 times more... more
The Justice Department on Monday accused a defunct chain of Tennessee-based pain clinics of cheating Medicare and other taxpayer-funded health insurers out of at... more
Researchers solve how the kava plant produces its pain-relieving and anti-anxiety molecules, demonstrate an extensible method to scale and optimize production. more
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Pain