Common antidepressants interact with the opioid pain medication tramadol to make it less effective for pain relief, according to a study from University Hospitals. more
More than 50 million U.S. adults have arthritis. Many experience severe joint pain and, likely because of their pain, don't do much exercising if at all. more
Common antidepressants interact with the opioid pain medication tramadol to make it less effective for pain relief, according to a new study. These findings have important implications for... more
When a patient complains about chest pain, diagnosis will usually involve catheter angiography to evaluate the adequacy of blood supply to the heart. Researchers have now established that, in certain cases, the diagnostic reliability of non-invasive... more
A new study shows that gut bacteria composition is different in people with fibromyalgia and that it varies with the severity of pain and other symptoms. more
A new study shows that gut bacteria composition is different in people with fibromyalgia and that it varies with the severity of pain and other symptoms. more
More than 5 million cancer survivors in the United States experience chronic pain, almost twice the rate in the general population, according to a study published by Mount... more
As opioid addiction and deadly overdoses escalated into an epidemic across the U.S., thousands of surgeons continued to hand out far more pills than needed for postoperative pain relief, according to a KHN-Johns Hopkins analysis of... more
Sortilin, which is a protein expressed on the surface of nerve cells, plays a crucial role in pain development in laboratory mice - and in all likelihood in humans as well. more
Pulmonary tuberculosis (TB) is a serious bacterial infection of the lungs. Symptoms include a persistent bad cough, chest pain, and breathlessness. TB can be life-threatening if a person does not... more
While effective drugs against chronic pain are not just around the corner, researchers have succeeded in identifying a protein as a future potential target for medicinal drugs. Basic research shows that blocking a protein... more
Rheumatoid arthritis (RA) is a chronic condition that causes pain and swelling in the joints. A growing body of scientific research suggests that turmeric and one of its main compounds,... more
Neuropathic pain is a major incurable clinical problem resulting from peripheral nerve trauma or disease. A central mechanism is the reduced expression of the potassium chloride... more
Lyme disease can cause long-term joint inflammation that lasts long after the body has cleared the infection. A new study uncovers how this might happen. more
Depression is a disorder that often comes along with strong impairments of social functioning. Until recently, researchers assumed that acute episodes of depression also impair empathy, an essential skill for successful social... more
As the opioid epidemic continues to claim lives and shatter families across the nation, a Cedars-Sinai expert is urging physicians and patients to try... more
New findings by researchers at the Kansas State University College of Veterinary Medicine suggest potential pain relief for piglets by administering medicine through the act of... more
After smouldering in the Democratic Republic of Congo (DRC) for almost a year, killing near 1,000 people, the deadly Ebola virus crossed the border to Uganda in June 2109. This virus causes... more
Antibodies that exist in the joints before the onset of rheumatoid arthritis can cause pain even in the absence of arthritis, researchers from Karolinska Institutet in Sweden report. more
A new study finds that antibodies that exist in the joints before the onset of rheumatoid arthritis can cause pain even in the absence of arthritis. Researchers believe that the finding can... more
Researchers have reported the first case of successful, long-term relief of chronic refractory shoulder pain in a wheelchair user with spinal cord injury following... more
Alternatives to opioids for treating pain are sorely needed. A study in rats suggests that tetrodotoxin, properly packaged, offers a potentially safe pain block. more
Ketamine is a darling of combat medics and clubgoers, an anesthetic that can quiet your pain without suppressing breathing and a hallucinogenic that can get you... more
The medical use of cannabis is growing. Medical marijuana may improve symptoms including pain and anorexia. While it may improve nausea and vomiting, it can rarely cause a... more
Lower back and leg pain can result from poor posture and overstraining the back muscles. However, persistent or recurring pain can be a sign of an... more
Researchers at Swinburne have developed a collaborative robot system to automatically treat back, neck and head pain caused by soft tissue injury. more
Changing how the mind reacts to pain can reduce the discomfort experienced, according to scientists who study brain pathways that regulate pain. A new type of therapy aims to enhance that effect. more
Some people find painful sensations pleasurable or arousing during sex or erotic play. How is this possible? Read this Spotlight feature to find out. more
Pain around the ribs is a common complaint during pregnancy. In this article, we look at the possible causes of rib pain during pregnancy and provide... more
The National Institutes of Health will fund clinical trials to assess the benefits, applicability and efficacy of applying genomic medicine interventions to... more
A European Journal of Cancer Care study found that listening to music at home reduced the severity of symptoms, pain intensity, and fatigue experienced... more
Scoliosis is a condition in which the spine curves to either side. Exercise and stretches are a vital part of treatment and can help relieve pain. Learn about the best... more
There's a better way to take care of patients after C-sections to help them heal faster and manage pain without increasing their risk of long-term opioid use, researchers say. more
Lower back pain is very common and often the result of a minor injury or overuse. However, it can sometimes be a symptom of conditions that affect the spine, such as spinal stenosis, degenerative disc disease,... more
Lower back pain is very common and often the result of a minor injury or overuse. However, it can sometimes be a symptom of conditions that affect the spine, such... more
Lower back and testicle pain can indicate an underlying condition that requires medical attention. Possible causes include kidney stones, urinary tract infections (UTIs), and spinal problems.... more
Evidence that taking opioids will help people with chronic pain to sleep better is limited and of poor quality, according to an interdisciplinary team... more
Poor posture or tense or tired muscles can often lead to upper back pain or discomfort. Gently stretching the back and shoulders can help both relieve... more
A previously unknown autoimmune muscle disease involving sudden onset of debilitating muscle pain and weakness has been identified by researchers at Washington University School of Medicine in St.... more
A previously unknown autoimmune muscle disease involving sudden onset of debilitating muscle pain and weakness has been identified. The syndrome easily could be mistaken for other muscle diseases that require different treatment, so the... more
Signs of a sprained ankle include pain and swelling. Doctors grade sprains depending on severity. Causes include falling and overuse. Learn more... more
Trevor Dyson-Hudson, MD, director of the Center for Spinal Cord Injury Research at Kessler Foundation, was awarded a $549,000 grant by the New Jersey... more
A new report in Science provides the first evidence of a mammal - the highveld mole-rat - being immune to pain from exposure to allyl isothiocyanate, or AITC, the active ingredient of... more
Neuralgia is a condition that causes shooting and burning pain in the nerves. There are many types of neuralgia. Treatment options include medications and surgery. Learn more about neuralgia here. more
Neuralgia is a condition that causes shooting and burning pain in the nerves. There are many types of neuralgia. Treatment options include medications and surgery. Learn more about neuralgia here. more
African mole-rats are insensitive to many different kinds of pain. This characteristic has even allowed mole-rats to populate new habitats, researchers report. Thanks to a genetic change, the highveld mole-rat is able to live alongside venomous ants with... more
Noxious substances, called algogens, cause pain and are used as defensive weapons by plants and stinging insects. We identified four previously unknown instances of algogen-insensitivity by screening eight... more
African mole rats are insensitive to many kinds of pain. As an international research team led by the MDC's Gary Lewin reports in Science, this characteristic has allowed mole rats to populate new habitats.... more
Most patients seen in a hospital emergency department for chest pain did not experience major cardiac events within six months following discharge, new research from UC... more
Managers with Purdue Pharma's international arm, Mundipharma, have been swept up in a corruption scandal in Italy for allegedly paying a prominent pain doctor to push... more
Kratom is a Southeast Asian tree with a long history of use in traditional medicine. In the region, the plant's leaves are widely consumed for pain... more
Kratom is a Southeast Asian tree with a long history of use in traditional medicine. In the region, the plant's leaves are widely consumed for pain... more
Managers with Purdue Pharma's international arm, Mundipharma, have been swept up in a corruption scandal in Italy for allegedly paying a prominent pain doctor to push opioids more
Managers with Purdue Pharma's international arm, Mundipharma, have been swept up in a corruption scandal in Italy for allegedly paying a prominent pain doctor to push opioids. more
Drug companies being sued by the state of Oklahoma for fueling the state's opioid addiction crisis say the products they manufactured were heavily regulated by state and federal agencies and addressed an... more
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