Researchers in Japan have identified a new quality control system that allows cells to remove damaged and potentially toxic proteins from their surroundings.... NEWS MEDICAL · 2 months
Fast & effective removal of interfering proteins  NEWS MEDICAL · 2 weeks
Incorporating a novel dual hydrophobically treated matrix filter, Microlute™ Protein Precipitation Plate from Porvair Sciences set a new standard for labs looking to remove interfering proteins from serum, plasma or even whole blood samples... more
How understanding the dynamics of yeast prions can shed light on neurodegenerative diseases  SCIENCE DAILY · 1 day
Prions are a class of misfolded proteins that form aggregates called "amyloid fibrils." These aggregates are the main culprit behind severe mammalian... more
New insight on mechanism of prions brings hope for treating neurodegenerative diseases  NEWS MEDICAL · 2 days
Prions are a class of misfolded proteins that form aggregates called "amyloid fibrils." These aggregates are the main culprit behind severe mammalian neurodegenerative diseases... more
Old human cells regain youthful strength after rejuvenating protein treatment, study finds  NEWS MEDICAL · 2 weeks
Old human cells return to a more youthful and vigorous state after being induced to briefly express a panel of proteins involved in embryonic... more
New UCI-led study reveals how skin cells prepare to heal wounds  NEWS MEDICAL · 3 weeks
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Composing new proteins with artificial intelligence  PHYS.ORG · 3 weeks
Proteins are the building blocks of life, and consequently, scientists have long studied how they can improve proteins and design completely new proteins that perform new functions and processes. more
Study reveals major changes that occur in mammalian skin cells during wound healing  NEWS MEDICAL · 3 weeks
A team of University of California, Irvine researchers have published the first comprehensive overview of the major changes that occur in mammalian... more
Study: The strength of collagen influenced by intersections of fibers  PHYS.ORG · 5 days
Collagen is the glue that holds bodies together. It can be found in skin, bones, muscles, cartilage, ligaments, hair, nails—in short, in almost every tissue. In some tissues... more
Strong signals show how proteins come and go  PHYS.ORG · 1 month
A novel system to amplify gene expression signals could be a game-changer for scientists who study the regulatory processes in cells that are central to all life. more
Hero proteins are here to save other proteins  PHYS.ORG · 4 weeks
Researchers at the University of Tokyo have discovered a new group of proteins, remarkable for their unusual shape and abilities to protect against protein clumps associated with neurodegenerative diseases in lab experiments.... more
How 'pioneer' protein turns stem cells into organs  PHYS.ORG · 3 weeks
Early on in each cell, a critical protein known as FoxA2 simultaneously binds to both the chromosomal proteins and the DNA, opening the flood gates for gene activation, according to a new... more
Turning cells into computers with protein logic gates  nanowerk · 6 days
Biochemists have created 'smart' proteins that function inside human cells by turning genes on and off. more
Caught in a spin: Spiral vortex streamlines delivery of nanomaterials into cells  PHYS.ORG · 4 weeks
The membrane surrounding cells acts as a selective barrier, cradling and protecting the cell's contents from the external surroundings and choosing which substances to... more
Changes in surface sugarlike molecules help cancer cells to spread  NEWS MEDICAL · 2 weeks
Changes in a specific type of sugarlike molecule, or glycan, on the surface of cancer cells help them to spread into other tissues, according to researchers at the... more
Physical force alone spurs gene expression, study reveals  PHYS.ORG · 1 week
Cells will ramp up gene expression in response to physical forces alone, a new study finds. Gene activation, the first step of protein production, starts less than one millisecond after a cell... more
New technique 'prints' cells to create diverse biological environments  nanowerk · 3 weeks
Researchers have created a new technique that utilizes photolithography and programmable DNA to rapidly 'print' two-dimensional arrays of cells and proteins that mimic a wide variety of cellular environments in... more
New 3-D cultured cells mimic the progress of NASH  PHYS.ORG · 1 week
A research team led by scientists from Tokyo University of Agriculture and Technology (TUAT), Japan, has successfully established 3-D cultured tissue that mimics liver fibrosis, a key characteristic of non-alcoholic... more
Immunotherapy using 'young cells' offers promising option against cancer  SCIENCE DAILY · 2 weeks
A new study suggests that the age of certain immune cells used in immunotherapy plays a role in how effective it is. These cells -- natural killer (NK) cells --... more
Digestive symptoms are common in COVID-19 patients, study reveals  NEWS MEDICAL · 3 weeks
The American Journal of Gastroenterology published today a new study that reveals digestive symptoms, including diarrhea, are common in COVID-19 patients. The study comes from the Wuhan Medical Treatment Expert... more
Study reveals new mechanism underlying organelle communication in brown fat cells  NEWS MEDICAL · 1 week
In recent years, brown fat has garnered increasing attention as the so-called good fat that can protect against obesity and associated health risks, like cardiovascular disease... more
Hidden messages in protein blueprints  SCIENCE DAILY · 1 week
Scientists have identified a new control mechanism that enables stem cells to adapt their activity in emergency situations. For this purpose, the stem cells simultaneously modify the blueprints for hundreds of proteins encoded in the gene transcripts. In... more
Genetically targeted chemical assembly of functional materials in living cells, tissues, and animals  Science Magazine · 3 weeks
The structural and functional complexity of multicellular biological systems, such as the brain, are beyond the reach of human design or assembly... more
Turning cells into computers with protein logic gates  SCIENCE DAILY · 5 days
New artificial proteins have been created to function as molecular logic gates. Like their electronic counterparts in computers, these biochemical tools can be used to program the behavior of complex systems, such... more
Global crotonylome reveals CDYL-regulated RPA1 crotonylation in homologous recombination-mediated DNA repair  Science Magazine · 4 weeks
Previously, we reported that chromodomain Y–like (CDYL) acts as a crotonyl–coenzyme A hydratase and negatively regulates histone crotonylation (Kcr). However, the global CDYL-regulated crotonylome remains unclear.... more
Study shows way to safely remove low-risk penicillin allergy labels in ICU patients  NEWS MEDICAL · 6 days
Many patients previously diagnosed with a penicillin allergy can have their allergy label removed after testing and safely undergo treatment with penicillin... more
New study overturns ‘snapshot’ model of cell cycle accepted since 1974  NEWS MEDICAL · 6 days
Cells have a big decision: Should they replicate or sleep? Healthy cells can go either way. Cancer cells' replication switches are stuck in the 'on' position. more
Study reveals collective dynamics of active matter systems  PHYS.ORG · 4 weeks
Flocks of starlings that produce dazzling patterns across the sky are natural examples of active matter—groups of individual agents coming together to create collective dynamics. In a study featured on the cover... more
Researchers make first direct measurement of the physical force of invading cancer cells  PHYS.ORG · 1 week
International research led by the University of St Andrews reveals the first direct measurement of the force cancer cells can apply when they... more
Salivary gland macrophages and tissue-resident CD8+ T cells cooperate for homeostatic organ surveillance  Science Magazine · 5 days
It is well established that tissue macrophages and tissue-resident memory CD8+ T cells (TRM) play important roles for pathogen sensing and rapid... more
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