Pancreatic cancer has one of the worst survival rates among cancers. Patients can expect as low as a 9% chance to live for at least five years after being diagnosed.... NEWS MEDICAL · 2 months
Starving pancreatic cancer cells of cysteine may induce tumor ferroptosis  NEWS MEDICAL · 6 days
A new study from Columbia University Irving Medical Center and the Herbert Irving Comprehensive Cancer Center suggests a compound in development for a rare kidney stone disease may... more
Direct measurement of vertical forces shows correlation between mechanical activity and proteolytic ability of invadopodia  Science Magazine · 4 weeks
Mechanobiology plays a prominent role in cancer invasion and metastasis. The ability of a cancer to degrade extracellular... more
Research introduces a new concept of resectability in pancreatic cancer  NEWS MEDICAL · 4 weeks
Pancreatic cancer is predicted to become the second leading cause of cancer-related deaths by 2030. However, recent developments in staging and treatment provide options to improve the long-term... more
New drug combination found to be safe and well-tolerated in patients with pancreatic cancer  NEWS MEDICAL · 3 weeks
A new study has shown a novel peptide antagonist, given in combination with a PD-1 inhibitor, to be safe and... more
Unmasking a hidden killer: Successfully detecting cancer in blood of patients undergoing treatment  PHYS.ORG · 3 weeks
Pancreatic cancer is one of the most lethal cancers, but difficult to diagnose: few sufferers have symptoms until the cancer has become... more
Research reveals rising rates of liver cancer  NEWS MEDICAL · 2 weeks
New research reveals rising rates of liver cancer around the world, despite advances aimed at preventing the disease. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society. more
Microbial DNA in the blood could help identify who has cancer  NEWS MEDICAL · 4 weeks
When Gregory Poore was a freshman in college, his otherwise healthy grandmother was shocked to learn that she had late-stage pancreatic cancer. The condition was diagnosed... more
Research reveals bias and stereotyping when recruiting patients for oncology clinical trials  NEWS MEDICAL · 4 weeks
New research reveals bias and stereotyping among clinical and research professionals who recruit patients to enroll in cancer clinical trials. The findings are published... more
Starving pancreatic cancer of cysteine may kill tumor cells  SCIENCE DAILY · 5 days
In a new study of mice, researchers have found that an experimental drug that breaks down the amino acid cysteine slows pancreatic tumor growth by causing ferroptosis, an unusual form... more
Transmission of COVID-19 among cancer patients in China  NEWS MEDICAL · 2 weeks
Researchers from Zhongnan Hospital of Wuhan University in China in collaboration with those from the National Cancer Centre Singapore, have come up with a study that reveals the transmission of the SARS-CoV-2... more
Irreversible TrxR1 inhibitors block STAT3 activity and induce cancer cell death  Science Magazine · 3 weeks
Because of its key role in cancer development and progression, STAT3 has become an attractive target for developing new cancer therapeutics. While several STAT3 inhibitors have... more
Turning colon cancer cells around  SCIENCE DAILY · 2 days
Using a modified natural substance along with current approaches could improve colon cancer treatment, according to findings by biologists. The discovery comes from their research into the role of an amino acid in tumor development and a potential... more
Researchers make first direct measurement of the physical force of invading cancer cells  PHYS.ORG · 1 week
International research led by the University of St Andrews reveals the first direct measurement of the force cancer cells can apply when they... more
Study shows disparities in guideline-concordant treatment for NSCLC patients  NEWS MEDICAL · 2 weeks
Lung cancer is the leading cause of cancer-associated deaths in the United States. Non-small cell lung cancer (NSCLC), a group of lung cancers named for the kinds of cells found... more
Maintaining VDR levels in pancreatic cells could protect against diabetes  NEWS MEDICAL · 2 weeks
Maintaining vitamin D receptor levels in pancreatic cells that synthesize and secrete insulin could contribute to protecting against the development of diabetes and counteract pancreatic cell damage caused... more
Purdue scientists aim to use protein power to halt tumor growth  NEWS MEDICAL · 20 hours
In 2018, approximately 324,000 men died from cancer in the United States. The combination of lung cancer, prostate cancer and colorectal cancer equated to half of... more
YAP signal pathway plays a vital role in the onset of head-and-neck cancer  NEWS MEDICAL · 2 weeks
Joint research between Kobe University and National Hospital Organization Kyushu Cancer Center has revealed that mice with mutations in the YAP signal... more
Bacteria-trapping protein may contribute to breast cancer metastasis  NEWS MEDICAL · 3 weeks
The protein peptidyl arginine deiminase 4 (PAD4), which enables some immune cells to trap bacteria, promoted breast cancer metastasis in mice when expressed in cancer cells, according to data published in Molecular... more
MCL1 protein essential in protecting the intestine against cancer development  NEWS MEDICAL · 3 weeks
An international team of researchers from the University of Zurich, the University Hospital Zurich, Heidelberg and Glasgow has identified a novel function for the cell death regulating protein... more
New marker may predict whether NSCLC tumor is likely to metastasize  NEWS MEDICAL · 4 weeks
Non-small cell lung cancer (NSCLC) is the most commonly diagnosed cancer, and the leading cause of cancer death worldwide. more
Study suggests potential therapeutic strategy against diabetes  NEWS MEDICAL · 2 weeks
Maintaining vitamin D receptor levels in pancreatic cells that synthesize and secrete insulin (β cells) could contribute to protecting against the development of diabetes and counteract pancreatic cell damage caused by the progression of... more
[Research Articles] Strong vaccine responses during chemotherapy are associated with prolonged cancer survival  Science Magazine · 3 weeks
Therapeutic cancer vaccines have effectively induced durable regressions of premalignant oncogenic human papilloma virus type 16 (HPV16)–induced anogenital lesions. However, the treatment... more
Cysteine depletion induces pancreatic tumor ferroptosis in mice  Science Magazine · 6 days
Ferroptosis is a form of cell death that results from the catastrophic accumulation of lipid reactive oxygen species (ROS). Oncogenic signaling elevates lipid ROS production in many tumor types and is counteracted... more
Fiber-rich diet linked with reduced risk of breast cancer  NEWS MEDICAL · 2 days
Consuming a diet high in fiber was linked with a reduced incidence of breast cancer in an analysis of all relevant prospective studies. The findings are published early online in... more
Colorectal cancer rates are increasing rapidly among young adults, study reveals  NEWS MEDICAL · 4 weeks
A population-based analysis from England indicates that the incidence of colorectal cancer is increasing rapidly in young adults. more
Experimental heart disease drug may treat chemo-resistant ovarian cancer  NEWS MEDICAL · 2 weeks
Most ovarian cancer starts in fallopian tubes. Then it sloughs from its site of origin and floats around in fluid until finding new sites of attachment. It's not easy for... more
How to continue providing optimal cancer care during novel coronavirus pandemic  NEWS MEDICAL · 3 weeks
Experts from the Seattle Cancer Care Alliance- a Member Institution of the National Comprehensive Cancer Network®- are sharing insights and advice on how to continue providing... more
Postmenopausal breast cancer and the benefit of genetic testing  NEWS MEDICAL · 4 weeks
A new study shows that genetic mutations could be detected in one in 40 women diagnosed with breast cancer before the age of 65 years. The study from Stanford researchers,... more
Researchers develop a microfluidic chip to help detect prostate cancer  NEWS MEDICAL · 4 weeks
Researchers of Sechenov University together with their colleagues from Australia used the microfluidics technology to develop a device able to isolate cancer cells from urine of patients with... more
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