Developing new medicines and understanding how they target specific organs often gives a crucial advantage in the fight against human diseases.... NEWS MEDICAL · 1 month
Study identifies two possible targets to halt liver damage in NASH  NEWS MEDICAL · 2 weeks
As much as 12 percent of adults in the United States are living with nonalcoholic steatohepatitis (NASH), an aggressive condition that can lead to cirrhosis or... more
Study identifies potential drug target and way to alleviate cerebral malaria  NEWS MEDICAL · 2 weeks
Scientists have identified a key molecule involved in the development of cerebral malaria, a deadly form of the tropical disease. The study identifies a potential drug... more
Scientists report promising activity of novel targeted drug in patients with advanced kidney cancer  NEWS MEDICAL · 1 week
Scientists report promising activity of a novel drug that targets a key molecular driver of clear cell renal cell carcinoma... more
Artificial intelligence yields new antibiotic  MIT · 3 days
A deep-learning model identifies a powerful new drug that can kill many species of antibiotic-resistant bacteria. more
Researchers look to fungus to shed light on cancer  PHYS.ORG · 2 weeks
A fungus that attacks almond and peach trees may be key to identifying new drug targets for cancer therapy. more
[Editors' Choice] Microfluidic modeling of bone marrow pathophysiology  Science Magazine · 4 days
Human bone-marrow-on-a-chip improves drug studies of hematopoietic cell function and identifies a neutrophil maturation defect in a genetic disorder. more
Two new grants will help researchers to study neurotechnology, drug delivery system  NEWS MEDICAL · 5 hours
Two grants will fund interdisciplinary research at the Beckman Institute for Advanced Science and Technology, including a look at how neurons and muscle cells... more
Drug lord's hippos make their mark on foreign ecosystem  PHYS.ORG · 4 weeks
Four hours east of Medellin in northern Colombia's Puerto Triunfo municipality, the sprawling hacienda constructed by infamous drug lord Pablo Escobar of "Narcos" fame has become a tourist attraction. When... more
Finely tuned nervous systems allowed birds and mammals to adopt smoother strides  PHYS.ORG · 4 weeks
Since the 1900s, neuroscientists have known that the peripheral nervous systems of tetrapods (four-footed animals) vary greatly, but how these differences affect the way... more
Discovery paves path forward in the fight against the deadliest form of malaria  SCIENCE DAILY · 2 weeks
Scientists have identified a key molecule involved in the development of cerebral malaria, a deadly form of the tropical disease. The study... more
Therapeutic cooling effectively targets site of brain injury  SCIENCE DAILY · 2 days
Investigators successfully measure brain temperature in newborn babies undergoing therapeutic cooling, showing that the treatment effectively targets the core of the brain. more
New technology enables scientists to analyze behavior of cancer cells in lab-grown tumors  NEWS MEDICAL · 6 days
New technology developed at UCL is, for the first time, enabling cancer scientists to analyze the individual behavior of millions of different... more
Discovery identifies an adaptation by cancer cells that promotes metastasis  NEWS MEDICAL · 2 weeks
The discovery identifies an adaptation by cancer cells that facilitates their spreading to distant sites, and the potential for targeting these features to prevent or slow the progression... more
Global warming and extinction risk  SCIENCE DAILY · 2 weeks
How can fossils predict the consequences of climate change? A research team compared data from fossil and marine organisms living today to predict which groups of animals are most at risk from climate change. more
Seeking better guidelines for inventorying greenhouse gas emissions  PHYS.ORG · 3 weeks
In the face of a changing climate, the process of accounting greenhouse gas emissions is becoming ever more critical. Governments around the world are striving to hit reduction targets using Intergovernmental Panel... more
FDA approves new drug that could aid MS diagnoses for clinical trials  NEWS MEDICAL · 4 weeks
A new drug that could make it easier for doctors to diagnose multiple sclerosis in its earlier stages has been approved for its first... more
Human organ chips for better drug development  NEWS MEDICAL · 4 weeks
The process of developing new drugs is both difficult and costly. It is estimated that of all the drug candidates which start out on their testing journey, less than 14% actually make it to... more
Drug To Prevent Premature Birth Divides Doctors, Insurers And FDA Experts  NPR · 4 weeks
An expert panel convened by the FDA says the drug Makena should be withdrawn from the market because a review of its effectiveness shows it doesn't... more
SwRI's Rhodium evaluates drug compounds for possible treatment of coronavirus  NEWS MEDICAL · 3 days
Drug discovery software at Southwest Research Institute is expanding the capacity to virtually screen drug compounds for possible treatment of coronavirus and other infectious diseases. more
Light-induced control of protein destruction by opto-PROTAC  Science Magazine · 2 days
By hijacking endogenous E3 ligase to degrade protein targets via the ubiquitin-proteasome system, PROTACs (PRoteolysis TArgeting Chimeras) provide a new strategy to inhibit protein targets that were regarded as undruggable before. However, the catalytic... more
These plants and animals are now flourishing as life creeps back after bushfires  PHYS.ORG · 5 days
As the east coast bushfire crisis finally abates, it's easy to see nothing but loss: more than 11 million hectares of charcoal... more
Unexpected insights into the dynamic structure of mitochondria  SCIENCE DAILY · 4 days
As power plants and energy stores, mitochondria are essential components of almost all cells in plants, fungi and animals. Until now, it has been assumed that these functions underlie a static structure... more
Global warming and extinction risk  PHYS.ORG · 2 weeks
How can fossils predict the consequences of climate change? A German research team from FAU, the Museum of Natural History Berlin and the Alfred Wegener Institute compared data from fossil and marine organisms living today to predict which... more
Living in greener neighborhoods may delay onset of menopause  NEWS MEDICAL · 1 week
Living near green spaces is associated with a wide variety of benefits, including a lower risk of obesity, improved attention capacity in children and slower physical decline in old age. more
SEER: A better tool to image disease  NEWS MEDICAL · 2 weeks
Scientists from the University of South California (USC) report the development of a novel technique to image living cells in greater detail and increased clarity. The study, published in the journal Nature Communications, describes... more
Color-Changing Paper-Based Bandages Sense, Selectively Treat Bacterial Infections  SCI-NEWS.COM · 4 weeks
A team of scientists has developed visualizing paper-based bandages that can sense drug-resistant and drug-sensitive bacteria in wounds and implement... more
Combination drug therapy for childhood brain tumors shows promise in laboratory models  SCIENCE DAILY · 6 days
In experiments with human cells and mice, researchers report evidence that combining the experimental cancer medication TAK228 (also called sapanisertib) with an existing anti-cancer... more
Enhancing drug testing with human body-on-chip systems  SCIENCE DAILY · 4 weeks
Scientists have devised a functioning comprehensive multi-Organ-on-a-Chip (Organ Chip) platform that enables effective preclinical drug testing of human drug pharmacology. more
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