Using a targeted gene epigenome editing approach in the developing mouse brain, researchers reversed one gene mutation that leads to the genetic disorder WAGR syndrome, which causes intellectual disability and obesity in people. This specific editing was unique in that it changed the epigenome -- how the genes are regulated -- without changing the actual genetic code of the gene being regulated.... SCIENCE DAILY · 1 month
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Nanoparticles deliver 'suicide gene' therapy to pediatric brain tumors growing in mice  SCIENCE DAILY · 2 weeks
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Biodegradable nanoparticle can deliver 'suicide gene' to pediatric brain tumor cells in mice  NEWS MEDICAL · 2 weeks
Johns Hopkins researchers report that a type of biodegradable, lab-engineered nanoparticle they fashioned can successfully deliver a "suicide gene" to pediatric brain... more
Nanoparticles deliver 'suicide gene' therapy to pediatric brain tumors growing in mice  PHYS.ORG · 2 weeks
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Horizon Discovery to offer novel base editing technology for clinical research  NEWS MEDICAL · 7 days
Horizon Discovery today announced that it will provide access to a novel base editing technology licensed from Rutgers for exclusive use in therapeutic, diagnostic and services... more
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Gene-editing tool's pioneers win Israel's Wolf Prize  PHYS.ORG · 1 week
Two global pioneers of modern gene-editing technology were awarded Monday Israel's prestigious Wolf Prize in medicine. more
Promega and MilliporeSigma sign license agreement to expand the potential of CRISPR  NEWS MEDICAL · 3 weeks
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A research team has discovered the first conclusive evidence that selection may also occur at the level of the epigenome -- a term that refers to an assortment of chemical... more
Combining neurologic and blood pressure drugs reduces breast tumor development in mice  SCIENCE DAILY · 3 weeks
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Findings may lead to potential therapeutic strategies for rare neurodevelopmental disorder  NEWS MEDICAL · 2 weeks
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Inputs to the motor cortex can guide dexterous movements in mice  NEWS MEDICAL · 4 weeks
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Essential tremor caused by overactive brain waves  NEWS MEDICAL · 5 days
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Drug trial seeking treatment option for hyperphagia in patients with Prader-Willi Syndrome  NEWS MEDICAL · 3 weeks
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