Comprehensive profiling of tumor samples taken from patients with osteosarcoma shows that multiple factors contribute to the traditionally poor responses observed from treatment with immune checkpoint inhibitors, according to new research from The University of Texas MD Anderson Cancer Center.... NEWS MEDICAL · 2 months
Study offers new insight into genetic alterations associated with osteosarcoma  NEWS MEDICAL · 3 weeks
A study by researchers at the National Cancer Institute, part of the National Institutes of Health, offers new insight into genetic alterations associated with osteosarcoma, the most common... more
Immunotherapy using 'young cells' offers promising option against cancer  SCIENCE DAILY · 2 weeks
A new study suggests that the age of certain immune cells used in immunotherapy plays a role in how effective it is. These cells -- natural killer (NK) cells --... more
Potential breakthrough in cancer immunotherapy with gasdermin E  NEWS MEDICAL · 4 weeks
A new study published in the journal Nature in March 2020 reports the discovery of a new approach to cancer immunotherapy, which could be useful in many more cancers than at present. more
Immunotherapy treatment shows promise for some patients with advanced rare cancers  NEWS MEDICAL · 3 weeks
A study conducted by researchers at The University of Texas MD Anderson Cancer Center demonstrated acceptable toxicity and anti-tumor activity in patients with four types of... more
Starving pancreatic cancer cells of cysteine may induce tumor ferroptosis  NEWS MEDICAL · 6 days
A new study from Columbia University Irving Medical Center and the Herbert Irving Comprehensive Cancer Center suggests a compound in development for a rare kidney stone disease may... more
Using 'young NK cells' could improve the effectiveness of immunotherapy for cancer patients  NEWS MEDICAL · 2 weeks
Immunotherapy that involves treating cancer with the body's own immune cells, or those of a matched donor, shows promise in clinical trials... more
Cancer could potentially be treated with new immunotherapy approach, say researchers  NEWS MEDICAL · 2 weeks
Researchers have made a discovery about EGR4 that could instigate a new immunotherapy approach to treating cancer. more
A bi-adjuvant nanovaccine that potentiates immunogenicity of neoantigen for combination immunotherapy of colorectal cancer  Science Magazine · 3 weeks
Neoantigen vaccines have been enthusiastically pursued for personalized cancer immunotherapy while vast majority of neoantigens have no or low immunogenicity.... more
Immunotherapy prior to surgery is effective in colon cancer  NEWS MEDICAL · 2 days
Patients with colon cancer, but no distant metastases, can benefit from immunotherapy while waiting for surgery. more
Research shows how immune cells act to limit tumor development  NEWS MEDICAL · 4 weeks
How does the immune system act to limit tumor development? Using in vivo imaging tools, scientists from the Institut Pasteur and Inserm described the spatiotemporal activity of tumor-infiltrating... more
Study reveals major changes that occur in mammalian skin cells during wound healing  NEWS MEDICAL · 3 weeks
A team of University of California, Irvine researchers have published the first comprehensive overview of the major changes that occur in mammalian... more
Plants and animals aren't so different when it comes to climate  SCIENCE DAILY · 2 weeks
A new study reveals that plants and animals are remarkably similar in their responses to changing environmental conditions across the globe, which may help explain how... more
Immunotherapy may benefit mCRPC patients with specific markers of immune activation  NEWS MEDICAL · 7 days
Although metastatic castration-resistant prostate cancer typically has limited response to immunotherapy, a subset of patients with pretreatment evidence of active T-cell responses in their tumors experienced... more
Multiplexed single-molecule enzyme activity analysis for counting disease-related proteins in biological samples  Science Magazine · 4 weeks
We established an ultrasensitive method for identifying multiple enzymes in biological samples by using a multiplexed microdevice-based single-molecule enzymatic assay. We used a paradigm... more
A previously unknown mechanism could be new therapeutic target for cancer immunotherapy  NEWS MEDICAL · 4 weeks
Researchers at UC have discovered a previously unknown mechanism that could explain the reason behind decreased immune function in cancer patients and could be... more
Study reveals secret of 18th century portrait  PHYS.ORG · 3 weeks
Russian researchers from the Moscow Institute of Physics and Technology, Kurnakov Institute of General and Inorganic Chemistry of RAS, and Russia's famed Tretyakov Gallery have conducted a comprehensive preconservation study of "The Portrait of... more
Study provides better understanding of how dangerous cancer metastases arise  NEWS MEDICAL · 2 weeks
In order to colonize other organs and grow into metastases, tumor cells that detach from the parent tumor need to manipulate their new microenvironment and create a 'metastatic... more
Study provides better understanding how dangerous cancer metastases arise  NEWS MEDICAL · 2 weeks
In order to colonize other organs and grow into metastases, tumor cells that detach from the parent tumor need to manipulate their new microenvironment and create a 'metastatic niche'. more
NK cells mediate clearance of CD8+ T cell-resistant tumors in response to STING agonists  Science Magazine · 3 weeks
Several immunotherapy approaches that mobilize CD8+ T cell responses stimulate tumor rejection, and some, such as checkpoint blockade, have been... more
Amplification and imaging of microRNA as a biomarker to detect tumor development  nanowerk · 3 weeks
Scientists found a way to amplify miRNA in live tumor cells for bioimaging. Their assay is based on a robust cellular autocatalytic biocircuit triggered... more
Gut bacteria can accumulate in tumors and improve effectiveness of cancer immunotherapy  NEWS MEDICAL · 4 weeks
Researchers at the University of Texas Southwestern Medical Center and University of Chicago have discovered that bacteria that usually live in the gut can... more
Novel immunotherapy eradicates solid tumors in mice without adverse side effects  NEWS MEDICAL · 1 week
Scientists have developed a new immunotherapy that eradicates solid tumors in mice without adverse side effects, according to a new study published today in eLife. more
CEL-SCI collaborates with UGA Center for Vaccines and Immunology to develop LEAPS COVID-19 immunotherapy  NEWS MEDICAL · 2 weeks
CEL-SCI Corporation announced today it has signed a collaboration agreement with the University of Georgia’s Center for Vaccines and Immunology... more
Cancer scientists aim to use protein power to stop tumor growth  SCIENCE DAILY · 1 day
Scientists have created a new therapy option that may help halt tumor growth in certain cancers such as prostate, which is among the most common types... more
Irradiated tumor cell-derived microparticles mediate tumor eradication via cell killing and immune reprogramming  Science Magazine · 2 weeks
Radiotherapy (RT) is routinely used in cancer treatment, but expansion of its clinical indications remains challenging. The mechanism underlying the radiation-induced bystander... more
Researchers take a big step towards a comprehensive single-cell atlas  PHYS.ORG · 2 weeks
A large team of researchers affiliated with multiple institutions in and around Hangzhou, China, has taken a very large step toward the creation of a comprehensive human single-cell... more
Starving pancreatic cancer of cysteine may kill tumor cells  SCIENCE DAILY · 5 days
In a new study of mice, researchers have found that an experimental drug that breaks down the amino acid cysteine slows pancreatic tumor growth by causing ferroptosis, an unusual form... more
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