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New blood test can predict drug resistance in patients with advanced prostate cancer
NEWS MEDICAL When bacteria develop antibiotic resistance, treatment with these medications becomes ineffective. Similarly, tumor cells can also change in such a way that... 2 hours
Id genes found to play crucial role in heart development
NEWS MEDICAL Researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP), the Cardiovascular Institute at Stanford University and other institutions were surprised to discover that the four genes in the Id family... 3 hours
Mouse model of human immune system inadequate for stem cell studies
SCIENCE DAILY A type of mouse widely used to assess how the human immune system responds to transplanted stem cells does not reflect what is likely to occur... 9 hours
Firing of neurons changes the cells that insulate them
SCIENCE DAILY Through their pattern of firing, neurons influence the behavior of the cells that upon maturation will provide insulation of neuronal axons, according to a new study. The findings suggest the... 10 hours
Vitamin C regulates stem cell function, curbs leukemia development, scientists discover
SCIENCE DAILY Not much is known about stem cell metabolism, but a new study from the Children's Medical Center Research Institute at UT Southwestern has found that stem... 11 hours
Rare resistance mutation reduces treatment choices for urinary tract infections
SCIENCE DAILY Nearly 20 percent of women aged 15-29 are diagnosed with a urinary tract infection (UTI). Now, investigators have uncovered a rare mutation that renders a UTI-causing pathogen resistant... 11 hours
Once invincible superbug squashed by 'superteam' of antibiotics
SCIENCE DAILY A team of three antibiotics has been assembled that, together, are capable of eradicating E. coli carrying mcr-1 and ndm-5 -- genes that make the bacterium immune to last-resort antibiotics, report researchers. 11 hours
Common antiseptic ingredients de-energize cells and impair hormone response
SCIENCE DAILY Quaternary ammonium compounds, or 'quats,' used as antimicrobial agents in common household products inhibit mitochondria, the powerhouses of the cell, as well as estrogenic functions in cells, a new in... 11 hours
New flying squirrel species discovered along North America's Pacific coast
SCIENCE DAILY Scientists always assumed it was a northern flying squirrel gliding through the canopies of Pacific coastal forests. But now a recent in-depth investigation of the animal's DNA is... 11 hours
Targeted forest regeneration: A blueprint for conserving tropical biological diversity?
SCIENCE DAILY Targeted forest regeneration among the largest and closest forest fragments in the Eastern Arc Mountains of Tanzania and the Atlantic Forest of Brazil can dramatically reduce extinction rates... 11 hours
miR-122 target sites in liver cancer: study links three genes to patient survival
SCIENCE DAILY A new study shows that a molecule that regulates liver-cell metabolism and suppresses liver-cancer development interacts with thousands of genes in liver... 11 hours
New high-throughput technique accelerates chemical screening to prioritize toxicity testing
NEWS MEDICAL Researchers from North Carolina State University have developed a high-throughput technique that can determine if a chemical has the potential to activate key genes in seconds rather than... 11 hours
Infection model developed for tickborne flaviviruses
SCIENCE DAILY Scientists have filled a research gap by developing a laboratory model to study ticks that transmit flaviviruses, such as Powassan virus. Powassan virus was implicated in the death of a New York man earlier this year.... 12 hours
Speeding up chemical screening to prioritize toxicity testing
SCIENCE DAILY Researchers have developed a high-throughput technique that can determine if a chemical has the potential to activate key genes in seconds rather than the typical 24 hours or more. The technique can... 12 hours
How humans and their gut microbes may respond to plant hormones
SCIENCE DAILY A bowl of salad contains more than vitamins and minerals. Plant matter also includes remnants of the hormones plants produce to control how they grow, age,... 12 hours
No microbes? No problem for caterpillars
SCIENCE DAILY Caterpillars have far less bacteria and fungi inhabiting their gut than other animals and the microbes that inside them seem to lack any identifiable role, aside from occasionally causing disease. 12 hours
Scientists find RNA with special role in nerve healing process
SCIENCE DAILY The discovery in lab mice that an 'anti-sense' RNA is expressed after nerve injury to regulate the repair of damage to the nerve's myelin coating could lead to... 12 hours
Oropouche virus could emerge and cause a public health problem
SCIENCE DAILY Brazil runs a serious risk of being afflicted by Oropouche, another virus that is widely distributed throughout South and Central America and the Caribbean. An arbovirus transmitted by... 12 hours
Medical News Today: Gut bacteria influence the brain indirectly, study shows
MNT A new study shows that some gut bacteria influence the brain through blood cortisol. This might have implications for ASD, but further studies are needed. 12 hours
Gut bacteria influence the brain indirectly, study shows
MNT A new study shows that some gut bacteria influence the brain through blood cortisol. This might have implications for ASD, but further studies are needed. 12 hours
How cytoplasm 'feels' to a cell's components
SCIENCE DAILY In a study that may guide drug design, researchers find organelles encounter varying levels of resistance, depending on their size and speed, as they move through a cell's cytoplasm. 12 hours
Newest solar cells underperform in cloudy countries
PHYS.ORG To determine how efficient new solar cells convert sunlight into electricity, small sample cells are tested under ideal conditions. However, the reported efficiency is not very representative of the actual annual yield when the... 13 hours
No microbes? No problem for caterpillars
PHYS.ORG The microbiome seems ubiquitous: humans and many other species rely on billions of tiny organisms in their guts to aid in digestion, metabolism and other functions. Now, scientists at the University of Colorado Boulder are questioning... 13 hours
Birth control research is moving beyond the pill
SCIENCE-NEWS After decades of research, reproductive biologists are on the verge of developing new birth control options that stop sperm from maturing or save a woman's eggs for later. 13 hours
Oropouche virus could cause serious public health problem in Brazil, researcher warns
NEWS MEDICAL After the Zika epidemic, which began in 2015, and the outbreak of yellow fever early in 2017, Brazil runs a serious risk of being... 13 hours
Getting hold of quantum dot biosensors
PHYS.ORG Quantum dots (QDs) have found so many applications in recent years, they can now be purchased with a variety of composite structures and configurations. Some are available suspended in a biologically friendly fluid, making them well... 14 hours
How humans and their gut microbes may respond to plant hormones
PHYS.ORG A bowl of salad contains more than vitamins and minerals. Plant matter also includes remnants of the hormones plants produce to control how they grow, age,... 14 hours
Cell biology: Molecular volume control and perceiving mechanical stimuli
SCIENCE DAILY About two years ago, scientists discovered that a certain class of receptors is capable of perceiving mechanical stimuli. Now they have begun to unravel the molecular mechanisms behind the discovery. 14 hours
Scientists identify genetic variation that promotes longevity in men
NEWS MEDICAL Researchers have found a mutation in the gene for the growth hormone receptor that promotes longevity, increasing men's lifespan by an average of 10 years. 14 hours
NIH scientists develop laboratory model to study tickborne flaviviruses
NEWS MEDICAL National Institutes of Health scientists have filled a research gap by developing a laboratory model to study ticks that transmit flaviviruses, such as Powassan virus. Powassan virus was implicated in... 14 hours
Where do heart cells come from?
SCIENCE DAILY Scientists were surprised to discover that the four genes in the Id family play a crucial role in heart development, telling undifferentiated stem cells to form heart tubes and eventually muscle. 14 hours
Key compounds to resolve abnormal vascular growth in age-related macular degeneration identified
SCIENCE DAILY A compound of specific bioactive products from a major family of enzymes reduced the severity of age-related macular degeneration (AMD) in a preclinical model,... 14 hours
Crystal structure reveals new details of nonstandard RNA transcription
SCIENCE DAILY By capturing the crystal structure of RNA polymerase during a nontraditional form of transcription -- reiterative transcription -- researchers have identified a new pathway used by RNA to exit an... 15 hours
You may be as friendly as your genes
SCIENCE DAILY Scientists have found that CD38 and CD157 genes that regulate oxytocin, the supreme human social hormone, are associated with the sociality of young individuals. They found that young adults who have higher... 15 hours
How a bacterium can live on methanol
SCIENCE DAILY Researchers have identified all the genes required by a bacterium to use methanol as a food source. The results will help scientists advance the use of this resource in the field of biotechnology. 16 hours
Cyborg bacteria outperform plants when turning sunlight into useful compounds
SCIENCE DAILY Photosynthesis provides energy for the vast majority of life on Earth. But chlorophyll, the green pigment that plants use to harvest sunlight, is relatively inefficient. To enable humans... 16 hours
Stretchable biofuel cells extract energy from sweat to power wearable devices
SCIENCE DAILY A team of engineers has developed stretchable fuel cells that extract energy from sweat and are capable of powering electronics, such as LEDs and Bluetooth radios.... 16 hours
Zika suppresses immune system during pregnancy to harm baby, report researchers
NEWS MEDICAL Scientists from the University of Southern California (USC) have discovered that the Zika virus works by suppressing a pregnant woman’s immune system so that the virus... 16 hours
Scientists identify key compound that reduces severity of AMD in preclinical model
NEWS MEDICAL A compound of specific bioactive products from a major family of enzymes reduced the severity of age-related macular degeneration (AMD) in a preclinical model,... 16 hours
Biotechnology researchers turn to landfill sites
PHYS.ORG Far from being a load of rubbish, landfill sites should be considered one of the great untapped resources in the search for new enzymes for biotechnology, and could fuel more efficient biofuel production. 17 hours
Genes that regulate oxytocin linked to sociality of young individuals
NEWS MEDICAL A group of researchers from the National University of Singapore has found that CD38 and CD157 genes that regulate oxytocin, the supreme human social hormone, are associated with... 17 hours
Technique expedites chemical screening to prioritize toxicity testing
PHYS.ORG Researchers from North Carolina State University have developed a high-throughput technique that can determine if a chemical has the potential to activate key genes in seconds rather than the typical 24 hours... 17 hours
How a bacterium can live on methanol
PHYS.ORG ETH Zurich researchers have identified all the genes required by a bacterium to use methanol as a food source. The results will help scientists advance the use of this resource in the field of... 17 hours
Expert discusses how cities should respond to urban vehicular attacks
PHYS.ORG Last week, a van was driven into pedestrians on Las Ramblas in Barcelona, killing 13 and injuring at least 130 people, and the driver then killed a 14th... 17 hours
New York's waterways are swimming in plastic microbeads
PHYS.ORG It's morning. Brush your teeth. A quick shower, shampoo. Going to the beach? Get on the sunscreen. OK, ready to roll. You've just sent countless microscopic plastic bits swirling down the drain, through the sewer... 17 hours
Scientists find soil bacteria require two-layer security, just like digital world
PHYS.ORG Those people at Google think they're sooooo smart. So, too, the Apple and Microsoft wunderkinds. 19 hours
How cytoplasm 'feels' to a cell's components
PHYS.ORG Under a microscope, a cell's cytoplasm can resemble a tiny underwater version of New York's Times Square: Thousands of proteins swarm through a cytoplasm's watery environment, coming together and breaking apart like a cytoskeletal... 19 hours
Algorithm speeds metabolic pathway analysis, spurring computational advances in network science
PHYS.ORG Scientists need a systematic understanding of cellular functioning to metabolically engineer microbes that produce biofuels and other high-value products, and to design drugs that combat pathogens... 19 hours
New open-source software for analyzing intact proteins
PHYS.ORG An estimated 20,300 genes in the human genome encode proteins. The number of proteins themselves, as intact proteoforms, could be as high as one billion. 19 hours
Crystal structure reveals details of nonstandard RNA transcription
PHYS.ORG High-resolution crystal structure reveals a new pathway for RNA during a nontraditional form of transcription—the process by which RNA is produced from a DNA template. Caught during the act of reiterative transcription,... 19 hours
Antimicrobial agents in common household products inhibit cell energy, estrogenic functions
NEWS MEDICAL A new in-vitro study by University of California, Davis, researchers indicates that quaternary ammonium compounds, or "quats," used as antimicrobial agents in common household products inhibit... 20 hours
cyborg bacteria outperform plants when turning sunlight into useful compounds Cyborg bacteria outperform plants when turning sunlight into useful compounds
PHYS.ORG VIDEO Photosynthesis provides energy for the vast majority of life on Earth. But chlorophyll, the green pigment that plants use to harvest sunlight, is relatively inefficient. To enable humans... 20 hours
Systematically studying slippery surfaces
PHYS.ORG Betaines are materials with both a positively charged functional group and a negatively charged functional group linked by an alkyl chain spacer. This combination of functional groups causes betaines to strongly attract water, which makes them useful for water retention.... 20 hours
Johns Hopkins researchers pinpoint how tiny protein could make deadly Ebola virus contagious
NEWS MEDICAL Two Johns Hopkins materials science graduate students and their professors played a key role in a multi-institution research project that pinpointed how... 20 hours
Novel nanolaser can serve as super-bright probe to detect and kill metastasized cancer cells
NEWS MEDICAL A nanolaser known as the spaser can serve as a super-bright, water-soluble, biocompatible probe capable of finding metastasized cancer cells... 20 hours
Medical News Today: Gut bacteria-produced compound may stave off aging
MNT A new study shows that a class of chemical compounds produced by gut bacteria and found in broccoli combats aging and considerably extends 'healthspan.' 21 hours
Gut bacteria-produced compound may stave off aging
MNT A new study shows that a class of chemical compounds produced by gut bacteria and found in broccoli combats aging and considerably extends 'healthspan.' 21 hours
MUSC researchers show how non-coding RNA promotes tumor formation
NEWS MEDICAL A mechanism that pushes a certain gene to produce a non-coding form of RNA instead of its protein-coding alternative can promote the growth of cancer, report researchers at the Medical University of... 23 hours
Biologists show how plants turn off genes they don't need
PHYS.ORG A plant has one genome, a specific sequence of millions of basepairs of nucleotides. Yet how this genome is expressed can vary from cell to cell, and it... 23 hours
Study offers new, quicker way to test for Zika virus
NEWS MEDICAL For the first time, researchers are using proteomics to examine proteins and peptides in saliva in order to accurately detect exposure to Zika virus. 1 day
Nanolaser can detect, kill circulating tumor cells to prevent cancer metastases, study finds
SCIENCE DAILY A nanolaser known as the spaser can serve as a super-bright, water-soluble, biocompatible probe capable of finding metastasized cancer cells in the... 1 day
How plants turn off genes they don't need
SCIENCE DAILY New research has identified small sequences in plant DNA that act as signposts for shutting off gene activity, directing the placement of proteins that silence gene expression. 1 day
Scientists reveal existence of alternative bacterial quorum-sensing mechanism
NEWS MEDICAL Whether growing in a puddle of dirty water or inside the human body, large groups of bacteria must coordinate their behavior to perform essential tasks that they would not be able to... 1 day
Plant virus-based system can be used to deliver anti-cancer drugs
NEWS MEDICAL An article published in Experimental Biology and Medicine (Volume 242, Issue 14, August 2017) reports that a plant virus-based system can be used to deliver anti-cancer drugs. 1 day
Mayo Clinic study reveals link between senescent cells and bone loss in mice
NEWS MEDICAL Mayo Clinic researchers have reported a causal link between senescent cells - the cells associated with aging and age-related disease - and... 1 day
Cortisol mediates communication between gut bacteria and brain metabolites, study suggests
NEWS MEDICAL Gut microbes have been in the news a lot lately. Recent studies show they can influence human health, behavior, and certain neurological disorders, such as autism. 1 day
Researchers find an alternative mode of bacterial quorum sensing
PHYS.ORG Whether growing in a puddle of dirty water or inside the human body, large groups of bacteria must coordinate their behavior to perform essential tasks that they would not be... 1 day
People favor highly reviewed products, even when they shouldn't
SCIENCE DAILY When we're trying to decide which cell phone case to buy or which hotel room to book, we often rely on the ratings and reviews of others to help us... 1 day
Materials scientists probe a protein's role in speeding Ebola's spread
SCIENCE DAILY Scientists have pinpointed how a tiny protein seems to make the deadly Ebola virus particularly contagious. 1 day
Chemicals from gut bacteria maintain vitality in aging animals
SCIENCE DAILY A class of chemicals made by intestinal bacteria, known as indoles, help worms, flies and mice maintain mobility and resilience for more of their lifespans, scientists have discovered. 1 day
Cholesterol-lowering drugs may fight infectious disease
SCIENCE DAILY Scientists found a gene variant that affects cholesterol levels also could increase the risk of contracting typhoid fever. A common cholesterol-lowering drug could protect animal models against Salmonella Typhi, the culprit behind the potentially deadly infection.... 1 day
Postnatal identification of Zika virus peptides from saliva
SCIENCE DAILY For the first time, researchers are using proteomics to examine proteins and peptides in saliva in order to accurately detect exposure to Zika virus. With 70 countries and territories reporting evidence of... 1 day
How cytoplasm “feels” to a cell’s components
MIT In study that may guide drug design, researchers find organelles encounter varying levels of resistance. 1 day
Chemicals from gut bacteria maintain vitality in aging animals
PHYS.ORG A class of chemicals made by intestinal bacteria, known as indoles, help worms, flies and mice maintain mobility and resilience for more of their lifespans, scientists have discovered. 1 day
Targeted forest regeneration: A blueprint for conserving tropical biological diversity?
PHYS.ORG Tropical forests contain more than one-half of all plant and animal species on Earth. Unfortunately, they are disappearing at the highest rate of any forests worldwide. Furthermore, many... 1 day
Virus reprograms ocean plankton
PHYS.ORG A virus which infects ocean plankton can reprogramme cells and change the way they absorb nutrients - potentially changing how carbon is stored in the ocean, new research shows. 1 day
Plants under heat stress must act surprisingly quickly to survive
PHYS.ORG In new results reported in The Plant Cell, molecular biologist Elizabeth Vierling at the University of Massachusetts Amherst and colleagues in India and China report finding a crucial... 1 day
Biofuels from bacteria
PHYS.ORG You might not cook with this sugar, but from a biofuels standpoint, it's pretty sweet. A Bay Area company has patented a group of three single-celled, algae-like organisms that, when grown together, can produce high quantities of sugar just right... 1 day
People favor highly reviewed products, even when they shouldn't
PHYS.ORG When we're trying to decide which cell phone case to buy or which hotel room to book, we often rely on the ratings and reviews of others to help us... 1 day
Antarctic salt-loving microbes provide insights into evolution of viruses
SCIENCE DAILY Scientists studying microbes from some of the saltiest lakes in Antarctica have discovered a new way the microbes can share DNA that could help them grow and survive. The research,... 1 day
'Exquisite selectivity' of neuronal wiring in the cerebral cortex revealed by research
SCIENCE DAILY Advanced technologies has been used to illuminate the connectivity pattern of chandelier cells, a distinctive kind of inhibitory cell type in the mammalian brain.... 1 day
Link between cells associated with aging, bone loss
SCIENCE DAILY A causal link between senescent cells -- the cells associated with aging and age-related disease -- and bone loss has been found in mice. Targeting these cells led to an increase in... 1 day
Biofuels from bacteria
SCIENCE DAILY Scientists are working toward a better understand whether cyanobacteria can be grown for biofuels on a large scale. 1 day
Searching for the 'signature' causes of BRCAness in breast cancer
SCIENCE DAILY Breast cancer cells with defects in the DNA damage repair-genes BRCA1 and BRCA2 have a mutational signature known in cancer genomics as 'Signature 3.' But not all breast... 1 day
Immune system can be modulated by targeted manipulation of cell metabolism
SCIENCE DAILY In its attempt to fight a serious bacterial infection, caused by listeria, for example, the immune system can become so over-activated that the resulting inflammatory response... 1 day
Researchers identify control mechanisms of synapse formation
NEWS MEDICAL DGIST announced that the research team of Professor Ko Jae-won at the Department of Brain & Cognitive Sciences and the research team of Professor Kim Ho-min at KAIST conducted a joint research and observed... 1 day
JAX wins NIGMS funding to decipher role of RNA structure in gene regulation
NEWS MEDICAL With new funding from the National Institute of General Medical Sciences totaling $2,059,618 over five years, JAX Assistant Professor Zhengqing Ouyang, Ph.D.,... 1 day
Medical News Today: Osteoporosis: Potential new drug target uncovered
MNT A new study finds that targeting the body's aging-related cells maintains and increases bone formation and improves bone mass and strength in aging mice. 2 days
Gut microbes may talk to the brain through cortisol
SCIENCE DAILY Gut microbes have been in the news lately. Recent studies show they can influence human health, behavior, and certain neurological disorders, such as autism. But just how do they communicate... 2 days
Identifying vulnerabilities posed by synthetic biology
SCIENCE DAILY Given the possible security vulnerabilities related to developments in synthetic biology -- a field that uses technologies to modify or create organisms or biological components -- a new report proposes a framework to identify and prioritize... 2 days
Zika virus stifles pregnant women's weakened immune system to harm baby
SCIENCE DAILY The Zika virus suppresses a pregnant woman's immune system, enabling the virus to spread and increasing the chances an unborn baby will be harmed, study finds.... 2 days
How a non-coding RNA encourages cancer growth and metastasis
SCIENCE DAILY A pro-tumor environment in the cell can encourage a gene to produce an alternative form of RNA that enables cancer to spread, report researchers. 2 days
Repairing damaged hearts with self-healing heart cells
SCIENCE DAILY New research has discovered a potential means to trigger damaged heart cells to self-heal. The discovery could lead to groundbreaking forms of treatment for heart diseases. For the first time, researchers have identified a... 2 days
Researchers discover potential way to trigger regeneration, repair of damaged heart cells
NEWS MEDICAL New research has discovered a potential means to trigger damaged heart cells to self-heal. The discovery could lead to groundbreaking forms of treatment for... 2 days
Study: Breast Milk Oligosaccharides Kill Group B-Streptococcus, Block Biofilm Formation
SCI-NEWS.COM Streptococcus agalactiae (Group B-Streptococcus, or GBS) is a type of bacteria that can cause invasive infections... 2 days
Medical News Today: Human milk sugars may protect against group B strep
MNT A new study presented at a conference finds that some breast milk contains sugars that may protect against group B strep microbial and biofilm... 2 days
First integrated atlas of microRNA expression in human primary cells
PHYS.ORG The human body consists of hundreds of different cell types with very different functions and behaviors, despite the fact that the genome sequence of almost all cells of... 2 days
Antarctic salt-loving microbes provide insights into evolution of viruses
PHYS.ORG UNSW Sydney scientists studying microbes from some of the saltiest lakes in Antarctica have discovered a new way that the microbes can share DNA that could help them grow and... 2 days
Comprehensive genomic analysis offers insights into causes of Wilms tumor development
SCIENCE DAILY Mutations involving a large number of genes converge on two pathways during early kidney development that lead to Wilms tumor, new research concludes. 2 days
Spaser can detect, kill circulating tumor cells to prevent cancer metastases, study finds
SCIENCE DAILY A nanolaser known as the spaser can serve as a super-bright, water-soluble, biocompatible probe capable of finding metastasized cancer cells in the... 2 days
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Cyborg bacteria outperform plants when turning sunlight into useful compounds
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How we inherit masculine and feminine behaviours: a new idea about environment and genes
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