Genetics
China draws up tighter rules on human gene and embryo trials: Xinhua  REUTERS · 1 day
China's top legislature will consider tougher rules on research involving human genes and embryos, the first such move since a Chinese scientist sparked controversy... more
A universal framework combining genome annotation and undergraduate education  PHYS.ORG · 2 days
As genome sequencing becomes cheaper and faster, resulting in an exponential increase in data, the need for efficiency in predicting gene function is growing, as is the need to train... more
A specific gene-microbe interaction drives the development of Crohns disease-like colitis in mice  Science Magazine · 2 days
Bacterial dysbiosis is associated with Crohn’s disease (CD), a chronic intestinal inflammatory disorder thought to result from an abnormal immune response against... more
Warming: Plants are also stressed out  SCIENCE DAILY · 2 days
What will a three-degree-warmer world look like? When experiencing stress or damage from various sources, plants use chloroplast-to-nucleus communication to regulate gene expression and help them cope. Now, researchers have found that GUN1 -- a gene... more
From nata de coco to computer screens: Cellulose gets a chance to shine  SCIENCE DAILY · 2 days
Researchers meticulously measured the optical birefringence of highly aligned cellulose nanofibers, paving the way for sharper television, computer, and smartphone screens. more
Scientists uncover a link between RNA editing and chloroplast-to-nucleus communication  PHYS.ORG · 2 days
What will a three-degree-warmer world look like? How will plants fare in more extreme weather conditions? When experiencing stress or damage from various sources, plants use chloroplast-to-nucleus communication... more
Scientists discover sustainable way to increase seed oil yield in crops  PHYS.ORG · 3 days
Nanyang Technological University, Singapore (NTU Singapore) scientists have developed a sustainable way to demonstrate a new genetic modification that can increase the yield of natural oil... more
Fuel cells in bacteria  PHYS.ORG · 3 days
The exchange of nitrogen between the atmosphere and organic matter is crucial for life on Earth because nitrogen is a major component of essential molecules such as proteins and DNA. One major route for this exchange, discovered only in the... more
BRB-seq: The quick and cheaper future of RNA sequencing  PHYS.ORG · 3 days
RNA sequencing is a technique used to analyze entire genomes by looking at the expression of their genes. Today, such genome-wide expression analyses are a standard tool for genomic studies... more
Taming the genome's 'jumping' sequences  PHYS.ORG · 3 days
The human genome is fascinating. Once predicted to contain about a hundred thousand protein-coding genes, it now seems that the number is closer to twenty thousand, and maybe less. And although our genome is made up of about... more
From nata de coco to computer screens: Cellulose gets a chance to shine  PHYS.ORG · 3 days
A team at the Institute of Scientific and Industrial Research at Osaka University has determined the optical parameters of cellulose molecules with... more
New scoring system based on genetic markers predicts obesity risk at birth  NEWS MEDICAL · 3 days
Researchers have come up with a scoring system based on genetic markers that predicts an individual's inborn risk for obesity. more
Scientists deploy CRISPR gene-editing tool to engineer multiple edits  NEWS MEDICAL · 3 days
Scientists at Christiana Care Health System's Gene Editing Institute and NovellusDx, an Israeli biotechnology company, have deployed a breakthrough CRISPR gene-editing tool to successfully engineer multiple edits simultaneously to fragments... more
KZFPs play a key role in the regulation of human genome  NEWS MEDICAL · 3 days
The human genome is fascinating. Once predicted to contain about a hundred thousand protein-coding genes, it now seems that the number is closer to twenty thousand,... more
Study compares effectiveness and cost of gene therapy and HSCT in major beta-thalassemia  NEWS MEDICAL · 3 days
Gene therapy offers the promise of a cure for beta-thalassemia and a new study has shown that it is associated with fewer... more
Scientists use NIR light and injected DNA nanodevice to guide stem cells to injury  NEWS MEDICAL · 3 days
What if doctors had a remote control that they could use to steer a patient's own cells to a wound... more
RNA sequencing used to discover novel genes and pathways in celiac disease  SCIENCE DAILY · 3 days
Researchers have discovered novel genes and pathways related to early stages in the development of celiac disease and the ongoing inflammation and comorbidities associated... more
BRB-seq: The quick and cheaper future of RNA sequencing  SCIENCE DAILY · 3 days
Bioengineers have developed a new method for Bulk RNA Sequencing that combines the multiplexing-driven cost-effectiveness of a single-cell RNA-seq workflow with the performance of a bulk RNA-seq procedure. more
New eDNA technology used to quickly assess coral reefs  SCIENCE DAILY · 3 days
Scientists have developed a technique for measuring the amount of living coral on a reef by analyzing DNA in small samples of seawater. more
Growing a cerebral tract in a microscale brain model  SCIENCE DAILY · 3 days
An international research team modeled the growth of cerebral tracts. Using neurons derived from stem cells, they grew cortical-like spheroids. In a microdevice, the spheroids extended bundles of axons toward... more
Bioengineers program cells as digital signal processors  SCIENCE DAILY · 3 days
Synthetic biologists have added high-precision analog-to-digital signal processing to the genetic circuitry of living cells. The research dramatically expands the chemical, physical and environmental cues engineers can use to prompt programmed responses from engineered... more
Genetic variants that protect against obesity could aid new weight loss medicines  SCIENCE DAILY · 3 days
Around four million people in the UK carry genetic variants that protect them from obesity, type 2 diabetes and heart disease, suggests new research.... more
Researchers use gene editing with CRISPR to treat lethal lung diseases before birth  SCIENCE DAILY · 3 days
Using CRISPR gene editing, researchers have thwarted a lethal lung disease in an animal model in which a harmful mutation causes death... more
Complex signal processing in synthetic gene circuits using cooperative regulatory assemblies  Science Magazine · 3 days
Eukaryotic genes are regulated by multivalent transcription factor complexes. Through cooperative self-assembly, these complexes perform non-linear regulatory operations involved in cellular decision-making and signal processing. Here,... more
Rare 'Bubble Boy Disease' Likely Cured with New Gene Therapy  LIVE SCIENCE · 3 days
Eight infants with a severe immune disorder, known as "bubble boy disease," appear to be cured of the disease thanks to an experimental gene therapy. more
Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1  Science Magazine · 3 days
Malignancies arising from mutation of tumor suppressors have unexplained tissue proclivity. For example, BAP1 encodes a widely expressed deubiquitinase for histone H2A,... more
Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq  Science Magazine · 3 days
CRISPR-Cas genome editing induces targeted DNA damage but can also affect off-target sites. Current off-target discovery methods work using purified DNA or specific cellular models but are incapable of direct... more
42,000-Year-Old Foal Entombed in Ice Still Had Liquid Blood in Its Veins  LIVE SCIENCE · 3 days
It's the oldest liquid blood on record, say scientists who want to clone the ice age horse. more
Disappearing bumblebee species under threat of extinction  SCIENCE DAILY · 3 days
The American Bumblebee - a species once more commonly seen buzzing around Southern Ontario - is critically endangered, according to a new study. The finding found the native North American species, Bombus pensylvanicus, is... more
A history of the Crusades, as told by crusaders' DNA  SCIENCE DAILY · 3 days
History can tell us a lot about the Crusades, the series of religious wars fought between 1095 and 1291, in which Christian invaders tried to claim the Near... more
Disappearing bumblebee species under threat of extinction  PHYS.ORG · 3 days
The American Bumblebee—a species once more commonly seen buzzing around Southern Ontario—is critically endangered, according to a new study led by York University. more
New gene therapy cures babies with fatal 'Bubble Boy' disease  NEWS MEDICAL · 3 days
A new gene therapy created by US researchers appears to have cured eight infant boys born with a rare genetic disorder referred to as “Bubble Boy” disease. more
Flies smell through a Gore-Tex system  PHYS.ORG · 3 days
A research group led by a scientist of the RIKEN Center for Biosystems Dynamics Research (BDR) has gained important insights into the nanopores that allow the fruit fly to detect chemicals in the air, and has... more
A history of the Crusades, as told by crusaders' DNA  PHYS.ORG · 3 days
History can tell us a lot about the Crusades, the series of religious wars fought between 1095 and 1291, in which Christian invaders tried to claim the Near... more
Study: Genetic test predicts middle-aged obesity risk  ABC NEWS · 3 days
Scientists say a genetic test can identify newborns at heightened risk of becoming severely obese by middle age, possibly giving time for interventions designed to head off that fate more
A genetic scorecard could predict your risk of being obese  SCIENCE-NEWS · 3 days
A genetic score predicts who is at risk of severe obesity, but experts say lifestyle matters more than genes. more
From nata de coco to computer screens: Cellulose gets a chance to shine  nanowerk · 3 days
Researchers meticulously measured the optical birefringence of highly aligned cellulose nanofibers, paving the way for sharper television, computer, and smartphone screens. more
The quest to save the banana from extinction  PHYS.ORG · 3 days
Panama disease, an infection that ravages banana plants, has been sweeping across Asia, Australia, the Middle East and Africa. The impact has been devastating. In the Philippines alone, losses have totalled US$400m.... more
Lasers make magnets behave like fluids  PHYS.ORG · 4 days
For years, researchers have pursued a strange phenomenon: When you hit an ultra-thin magnet with a laser, it suddenly de-magnetizes. Imagine the magnet on your refrigerator falling off. more
Lithium detected in an ancient star gives new clues for Big Bang nucleosynthesis  PHYS.ORG · 4 days
Researchers from the Instituto de Astrofísica de Canarias (Spain) and the University of Cambridge (UK) have detected lithium (Li) in the ancient... more
Making a fast ion transporter  PHYS.ORG · 4 days
An international team of researchers at Institute for Molecular Science in Japan and Max Planck Institute of Biophysics in Germany has revealed an ion transport mechanism of sodium/proton antiporter by simulating its motion. Based on the simulations, they... more
Genome analysis shows common origin of Pskov, Novgorod and Yakutia populations  PHYS.ORG · 4 days
Scientists have for the first time compared complete genome data of different ethnic groups in Russia. Using a special algorithm, they traced the genetic history for... more
Glowing millipede genitalia help scientists tell species apart  PHYS.ORG · 4 days
Sometimes, it's really easy for scientists to tell species of animals apart—they'll be obviously different shapes or colors. Other times, different species will look nearly identical to the naked eye. In those... more
Gene therapy restores immunity in infants with rare immunodeficiency disease  SCIENCE DAILY · 4 days
A small clinical trial has shown that gene therapy can safely correct the immune systems of infants newly diagnosed with a rare, life-threatening inherited disorder in which infection-fighting... more
Gene Therapy Advances To Better Treat 'Bubble Boy' Disease  NPR · 4 days
The latest advance is not only encouraging news for patients with severe compromised immunodeficiency. It's a test case for all those scientists working to develop better gene therapy techniques. more
The Cerrado once connected the Andes with the Atlantic Rainforest  SCIENCE DAILY · 4 days
A genetic and computational analysis of birds suggests that the Andean and Atlantic tropical forests, which are now almost a thousand kilometers apart, were connected via the Cerrado... more
New eDNA technology used to quickly assess coral reefs  PHYS.ORG · 4 days
Scientists at the University of Hawai`i at Mānoa Department of Biology have developed a technique for measuring the amount of living coral on a reef by analyzing DNA in small... more
Doctors use HIV in gene therapy to fix 'bubble boy' disease  ABC NEWS · 4 days
Eight babies who were born without a working germ-fighting system had their disease corrected by a gene therapy that ironically was made from one of the... more
Factors behind embryonic stem cell state  SCIENCE DAILY · 4 days
An international collaboration has found for the first time that two new epigenetic regulators, TAF5L and TAF6L, maintain self-renewal of embryonic stem cells. The scientists also found that these proteins activate c-Myc (a well-known cancer gene),... more
Making a fast ion transporter  SCIENCE DAILY · 4 days
An international team of researchers reveals an ion transport mechanism of sodium/proton antiporter by simulating its motion. Based on the simulations, they now design a faster transporter by making mutation on ''gate'' of the transporter. more
Genetics behind the evolution of flightless birds  SCIENCE DAILY · 4 days
Based on the analysis of the genomes of more than a dozen flightless birds, including an extinct moa, researchers found that while different species show wide variety in the protein-coding portions of their genome,... more
Volcanic Eruptions Caused End-Permian Extinction, New Evidence Confirms  SCI-NEWS.COM · 4 days
An international team of paleontologists from China and the United States has found high levels of mercury in the end-Permian... more
In vivo genome editing rescues photoreceptor degeneration via a Cas9/RecA-mediated homology-directed repair pathway  Science Magazine · 4 days
Although Cas9-mediated genome editing has been widely used to engineer alleles in animal models of human inherited diseases, very few homology-directed repair... more
The Suv420h histone methyltransferases regulate PPAR-{gamma} and energy expenditure in response to environmental stimuli  Science Magazine · 4 days
Obesity and its associated metabolic abnormalities have become a global emergency with considerable morbidity and mortality. Epidemiologic and animal model... more
[Research Articles] In utero gene editing for monogenic lung disease  Science Magazine · 4 days
Monogenic lung diseases that are caused by mutations in surfactant genes of the pulmonary epithelium are marked by perinatal lethal respiratory failure or chronic diffuse parenchymal lung disease... more
Funerary customs, diet, and social behavior in a pre-Roman Italian Celtic community  PHYS.ORG · 4 days
Analysis of human remains from a Pre-Roman Celtic cemetery in Italy shows variations in funerary treatment between individuals that could be related to social... more
CRISPR base editors can induce wide-ranging off-target RNA edits  PHYS.ORG · 4 days
A Massachusetts General Hospital (MGH) research team reports that several of the recently developed CRISPR base editors, which create targeted changes in a single DNA base, can induce widespread off-target... more
Injected DNA nanodevice as light-activated remote control for cells  nanowerk · 4 days
Researchers used near-infrared light and an injected DNA nanodevice to guide stem cells to an injury, which helped muscle tissue regrow in mice. more
A light-activated remote control for cells  SCIENCE DAILY · 4 days
What if doctors had a remote control that they could use to steer a patient's own cells to a wound to speed up the healing process? Although such a device is still far from reality, researchers... more
A light-activated remote control for cells  PHYS.ORG · 4 days
What if doctors had a remote control that they could use to steer a patient's own cells to a wound to speed up the healing process? Although such a device is still far from reality, researchers... more
Stanford clears faculty members in gene-edited baby inquiry  ABC NEWS · 4 days
Stanford University has cleared three faculty members of any wrongdoing in dealings with a Chinese scientist who claims to have helped make the world's first gene-edited babies more
Predicting electricity demands  PHYS.ORG · 5 days
Research published in the International Journal of Energy Technology and Policy shows how a neural network can be trained with a genetic algorithm to forecasting short-term demands on electricity load. Chawalit Jeenanunta and Darshana Abeyrathna of Thammasat University, in Thani,... more
Scientists crack the code to regenerate plant tissues  PHYS.ORG · 5 days
Plant regeneration can occur via formation of a mass of pluripotent cells. The process of acquisition of pluripotency involves silencing of genes to remove original tissue memory and priming for activation by... more
IDT partners with iGEM to support young researchers and promote scientific progress  NEWS MEDICAL · 5 days
As an advocate for researchers in synthetic biology, Integrated DNA Technologies is once again proudly partnering with the International Genetically Engineered Machine Foundation to... more
Timing of food intake influences molecular clock in the liver of mice  NEWS MEDICAL · 5 days
The timing of food intake is a major factor driving the rhythmic expression of most genes in the mouse liver, researchers report April 16... more
Printing nanoparticle shapes for medical applications  nanowerk · 5 days
Researchers have developed a technology to customize the shapes of polymers and polymeric nanoparticles using DNA. In both 2D and 3D, precise patterns of structures composed of biocompatible polymer materials can be easily designed and constructed... more
New study delves deeper into individual genomic differences than ever before  NEWS MEDICAL · 5 days
Human genomes vary quite a bit from individual to individual. These differences include single nucleotide changes, or "spelling mistakes" in the DNA sequence, but even more... more
Pollen genes mutate naturally in only some strains of corn  SCIENCE DAILY · 5 days
Pollen genes mutate naturally in only some strains of corn, according to research that helps explain the genetic instability in certain strains and may lead to better breeding... more
Linkage is a drag: First wheat gene to rapidly convert defective traits for new  SCIENCE DAILY · 5 days
In the quest to separate the good traits from the bad, bioinformatics (computational biology) research, using a data driven strategy... more
First U.S. Patients Treated With CRISPR As Human Gene-Editing Trials Get Underway  NPR · 5 days
This could be a crucial year for the powerful gene-editing technique CRISPR as researchers start testing it in patients to treat diseases such as... more
In mice, feeding time influences the liver's biological clock  SCIENCE DAILY · 5 days
The timing of food intake is a major factor driving the rhythmic expression of most genes in the mouse liver, researchers report. The findings demonstrate that body-wide signals driven by... more
Scientists 'reverse engineer' brain cancer cells to find new targets for treatment  SCIENCE DAILY · 5 days
Glioblastoma is one of the most devastating forms of cancer, with few existing treatment options. It is also a leading cause of cancer-related death... more
In mice, feeding time influences the liver's biological clock  PHYS.ORG · 5 days
The timing of food intake is a major factor driving the rhythmic expression of most genes in the mouse liver, researchers report April 16th in the journal Cell Reports. The... more
First U.S. Patients Treated With CRISPR As Gene-Editing Human Trials Get Underway  NPR · 5 days
This could be a crucial year for the powerful gene-editing technique CRISPR as researchers start testing it in patients to treat diseases such as... more
Cause of cancer is 'written' in our DNA as unique 'fingerprints'  NEWS MEDICAL · 5 days
Scientists have discovered that the cause of cancer is “written” within the DNA of tumors, a finding that could help doctors to decide on the best... more
Initial gene analysis could result in more effective antipsychotic treatment  NEWS MEDICAL · 6 days
An initial gene analysis may yield better outcomes when patients are treated with the antipsychotic drugs risperidone and aripiprazole. more
Scientists Plan To Start Human Trials Testing CRISPR Soon  NPR · 6 days
The powerful gene-editing technique is moving out of the lab and into the clinic. Trials will use CRISPR to try to treat a variety of diseases, ranging from cancer and... more
Researchers identify cause of inherited metabolic disorder  NEWS MEDICAL · 6 days
A new study from BC Children's Hospital, the University of British Columbia (UBC) and an international team of researchers published in the New England Journal of Medicine is the first to identify a rarely-seen... more
Researchers discover how liver cells protect against viral attacks  NEWS MEDICAL · 6 days
Liver cells have an innate resistance to RNA viral infections like hepatitis A, dengue and Zika thanks to a protein called IRF1, according to researchers at the University of North... more
Linkage is a drag: First wheat gene to rapidly convert defective traits for new  PHYS.ORG · 6 days
When it comes to breeding better wheat varieties, often, though we seek to introduce desirable genes that increase yield, for... more
CRISPR-scanning could lead to more effective treatments for cancer  NEWS MEDICAL · 6 days
11,000 people are predicted to die from acute myeloid leukemia in 2019, according to the American Cancer Society. The cancer starts in the bone marrow. There, mutated genes fail to... more
Researchers complete large analysis of new gene fusion responsible for development of cancers  NEWS MEDICAL · 6 days
A consortium of researchers led by Georgetown Lombardi Comprehensive Cancer Center investigators have completed the largest analysis of a new gene fusion... more
New catalog of DNA mutation 'fingerprints' could help doctors pinpoint cancer culprits  NEWS MEDICAL · 6 days
Scientists in Cambridge and London have developed a catalog of DNA mutation 'fingerprints' that could help doctors pinpoint the environmental culprit responsible for a... more
To protect stem cells, plants have diverse genetic backup plans  SCIENCE DAILY · 6 days
When it comes to stem cell management, all flowering plants work to maintain the same status quo. Researchers have now identified the various strategies plants use to preserve... more
Cause of rare genetic metabolic disorder  SCIENCE DAILY · 6 days
A new study is the first to identify a rarely-seen type of DNA mutation as the cause of an inherited metabolic disorder. Inherited metabolic disorders -- where the body can't break down specific nutrients from food... more
APOE gene impacts sleep depending on gender and severity of Alzheimer's  NEWS MEDICAL · 6 days
The gene most often associated with risk of Alzheimer's Disease impacts sleep depending on gender and the severity of Alzheimer's in a patient, suggests a study... more
Pollen genes mutate naturally in only some strains of corn  PHYS.ORG · 6 days
Pollen genes mutate naturally in only some strains of corn, according to Rutgers-led research that helps explain the genetic instability in certain strains and may lead to better... more
Gene-based factor VIIa prevents bleeding episodes in animals with hemophilia  PHYS.ORG · 6 days
Hematology researchers have further refined how a treatment currently used on an urgent basis to control bleeding in hemophilia patients holds promise as a preventive treatment as well.... more
DIY Gravitational Waves with 'BlackHoles@Home'  ASTRO WATCH · 6 days
Researchers hoping to better interpret data from the detection of gravitational waves generated by the collision of binary black holes are turning to the public for... more
Antimicrobial resistance gene: New gene variant is more resistant to hospital antiseptic  SCIENCE DAILY · 6 days
A team of investigators has discovered a new, more powerful variant on an antimicrobial resistance gene common among Staphylococcus species. The gene protects the... more
New compound allows bacterial communication to be controlled by light  SCIENCE DAILY · 6 days
Scientists have succeeded in incorporating a light-controlled switch into a molecule used by bacteria for quorum sensing -- a process by which bacteria communicate and subsequently control different... more
DNACRISPR
Researchers develop new platform that recreates cancer in a dish to quickly determine the best bacterial therapy
PHYS.ORG
A new bacteria-killing weapon in the fight against antibiotic resistance
PHYS.ORG
New imaging technique reveals 'burst' of activity before cell death
PHYS.ORG
Keeping genetic engineering localized
PHYS.ORG
Zooming in on an inner-cell DNA repair shop
PHYS.ORG
Fresh