China's top legislature will consider tougher rules on research involving human genes and embryos, the first such move since a Chinese scientist sparked controversy... more
As genome sequencing becomes cheaper and faster, resulting in an exponential increase in data, the need for efficiency in predicting gene function is growing, as is the need to train... more
Bacterial dysbiosis is associated with Crohn’s disease (CD), a chronic intestinal inflammatory disorder thought to result from an abnormal immune response against... more
What will a three-degree-warmer world look like? When experiencing stress or damage from various sources, plants use chloroplast-to-nucleus communication to regulate gene expression and help them cope. Now, researchers have found that GUN1 -- a gene... more
Researchers meticulously measured the optical birefringence of highly aligned cellulose nanofibers, paving the way for sharper television, computer, and smartphone screens. more
What will a three-degree-warmer world look like? How will plants fare in more extreme weather conditions? When experiencing stress or damage from various sources, plants use chloroplast-to-nucleus communication... more
Nanyang Technological University, Singapore (NTU Singapore) scientists have developed a sustainable way to demonstrate a new genetic modification that can increase the yield of natural oil... more
The exchange of nitrogen between the atmosphere and organic matter is crucial for life on Earth because nitrogen is a major component of essential molecules such as proteins and DNA. One major route for this exchange, discovered only in the... more
RNA sequencing is a technique used to analyze entire genomes by looking at the expression of their genes. Today, such genome-wide expression analyses are a standard tool for genomic studies... more
The human genome is fascinating. Once predicted to contain about a hundred thousand protein-coding genes, it now seems that the number is closer to twenty thousand, and maybe less. And although our genome is made up of about... more
A team at the Institute of Scientific and Industrial Research at Osaka University has determined the optical parameters of cellulose molecules with... more
Scientists at Christiana Care Health System's Gene Editing Institute and NovellusDx, an Israeli biotechnology company, have deployed a breakthrough CRISPR gene-editing tool to successfully engineer multiple edits simultaneously to fragments... more
The human genome is fascinating. Once predicted to contain about a hundred thousand protein-coding genes, it now seems that the number is closer to twenty thousand,... more
Researchers have discovered novel genes and pathways related to early stages in the development of celiac disease and the ongoing inflammation and comorbidities associated... more
Bioengineers have developed a new method for Bulk RNA Sequencing that combines the multiplexing-driven cost-effectiveness of a single-cell RNA-seq workflow with the performance of a bulk RNA-seq procedure. more
An international research team modeled the growth of cerebral tracts. Using neurons derived from stem cells, they grew cortical-like spheroids. In a microdevice, the spheroids extended bundles of axons toward... more
Synthetic biologists have added high-precision analog-to-digital signal processing to the genetic circuitry of living cells. The research dramatically expands the chemical, physical and environmental cues engineers can use to prompt programmed responses from engineered... more
Around four million people in the UK carry genetic variants that protect them from obesity, type 2 diabetes and heart disease, suggests new research.... more
Eukaryotic genes are regulated by multivalent transcription factor complexes. Through cooperative self-assembly, these complexes perform non-linear regulatory operations involved in cellular decision-making and signal processing. Here,... more
Eight infants with a severe immune disorder, known as "bubble boy disease," appear to be cured of the disease thanks to an experimental gene therapy. more
Malignancies arising from mutation of tumor suppressors have unexplained tissue proclivity. For example, BAP1 encodes a widely expressed deubiquitinase for histone H2A,... more
CRISPR-Cas genome editing induces targeted DNA damage but can also affect off-target sites. Current off-target discovery methods work using purified DNA or specific cellular models but are incapable of direct... more
The American Bumblebee - a species once more commonly seen buzzing around Southern Ontario - is critically endangered, according to a new study. The finding found the native North American species, Bombus pensylvanicus, is... more
History can tell us a lot about the Crusades, the series of religious wars fought between 1095 and 1291, in which Christian invaders tried to claim the Near... more
The American Bumblebee—a species once more commonly seen buzzing around Southern Ontario—is critically endangered, according to a new study led by York University. more
A new gene therapy created by US researchers appears to have cured eight infant boys born with a rare genetic disorder referred to as “Bubble Boy” disease. more
A research group led by a scientist of the RIKEN Center for Biosystems Dynamics Research (BDR) has gained important insights into the nanopores that allow the fruit fly to detect chemicals in the air, and has... more
History can tell us a lot about the Crusades, the series of religious wars fought between 1095 and 1291, in which Christian invaders tried to claim the Near... more
Scientists say a genetic test can identify newborns at heightened risk of becoming severely obese by middle age, possibly giving time for interventions designed to head off that fate more
Researchers meticulously measured the optical birefringence of highly aligned cellulose nanofibers, paving the way for sharper television, computer, and smartphone screens. more
Panama disease, an infection that ravages banana plants, has been sweeping across Asia, Australia, the Middle East and Africa. The impact has been devastating. In the Philippines alone, losses have totalled US$400m.... more
For years, researchers have pursued a strange phenomenon: When you hit an ultra-thin magnet with a laser, it suddenly de-magnetizes. Imagine the magnet on your refrigerator falling off. more
Researchers from the Instituto de Astrofísica de Canarias (Spain) and the University of Cambridge (UK) have detected lithium (Li) in the ancient... more
An international team of researchers at Institute for Molecular Science in Japan and Max Planck Institute of Biophysics in Germany has revealed an ion transport mechanism of sodium/proton antiporter by simulating its motion. Based on the simulations, they... more
Scientists have for the first time compared complete genome data of different ethnic groups in Russia. Using a special algorithm, they traced the genetic history for... more
Sometimes, it's really easy for scientists to tell species of animals apart—they'll be obviously different shapes or colors. Other times, different species will look nearly identical to the naked eye. In those... more
A small clinical trial has shown that gene therapy can safely correct the immune systems of infants newly diagnosed with a rare, life-threatening inherited disorder in which infection-fighting... more
The latest advance is not only encouraging news for patients with severe compromised immunodeficiency. It's a test case for all those scientists working to develop better gene therapy techniques. more
A genetic and computational analysis of birds suggests that the Andean and Atlantic tropical forests, which are now almost a thousand kilometers apart, were connected via the Cerrado... more
Scientists at the University of Hawai`i at Mānoa Department of Biology have developed a technique for measuring the amount of living coral on a reef by analyzing DNA in small... more
Eight babies who were born without a working germ-fighting system had their disease corrected by a gene therapy that ironically was made from one of the... more
An international collaboration has found for the first time that two new epigenetic regulators, TAF5L and TAF6L, maintain self-renewal of embryonic stem cells. The scientists also found that these proteins activate c-Myc (a well-known cancer gene),... more
An international team of researchers reveals an ion transport mechanism of sodium/proton antiporter by simulating its motion. Based on the simulations, they now design a faster transporter by making mutation on ''gate'' of the transporter. more
Based on the analysis of the genomes of more than a dozen flightless birds, including an extinct moa, researchers found that while different species show wide variety in the protein-coding portions of their genome,... more
Although Cas9-mediated genome editing has been widely used to engineer alleles in animal models of human inherited diseases, very few homology-directed repair... more
Obesity and its associated metabolic abnormalities have become a global emergency with considerable morbidity and mortality. Epidemiologic and animal model... more
Monogenic lung diseases that are caused by mutations in surfactant genes of the pulmonary epithelium are marked by perinatal lethal respiratory failure or chronic diffuse parenchymal lung disease... more
Analysis of human remains from a Pre-Roman Celtic cemetery in Italy shows variations in funerary treatment between individuals that could be related to social... more
A Massachusetts General Hospital (MGH) research team reports that several of the recently developed CRISPR base editors, which create targeted changes in a single DNA base, can induce widespread off-target... more
What if doctors had a remote control that they could use to steer a patient's own cells to a wound to speed up the healing process? Although such a device is still far from reality, researchers... more
What if doctors had a remote control that they could use to steer a patient's own cells to a wound to speed up the healing process? Although such a device is still far from reality, researchers... more
Stanford University has cleared three faculty members of any wrongdoing in dealings with a Chinese scientist who claims to have helped make the world's first gene-edited babies more
Research published in the International Journal of Energy Technology and Policy shows how a neural network can be trained with a genetic algorithm to forecasting short-term demands on electricity load. Chawalit Jeenanunta and Darshana Abeyrathna of Thammasat University, in Thani,... more
Plant regeneration can occur via formation of a mass of pluripotent cells. The process of acquisition of pluripotency involves silencing of genes to remove original tissue memory and priming for activation by... more
As an advocate for researchers in synthetic biology, Integrated DNA Technologies is once again proudly partnering with the International Genetically Engineered Machine Foundation to... more
Researchers have developed a technology to customize the shapes of polymers and polymeric nanoparticles using DNA. In both 2D and 3D, precise patterns of structures composed of biocompatible polymer materials can be easily designed and constructed... more
Human genomes vary quite a bit from individual to individual. These differences include single nucleotide changes, or "spelling mistakes" in the DNA sequence, but even more... more
Pollen genes mutate naturally in only some strains of corn, according to research that helps explain the genetic instability in certain strains and may lead to better breeding... more
This could be a crucial year for the powerful gene-editing technique CRISPR as researchers start testing it in patients to treat diseases such as... more
The timing of food intake is a major factor driving the rhythmic expression of most genes in the mouse liver, researchers report. The findings demonstrate that body-wide signals driven by... more
Glioblastoma is one of the most devastating forms of cancer, with few existing treatment options. It is also a leading cause of cancer-related death... more
The timing of food intake is a major factor driving the rhythmic expression of most genes in the mouse liver, researchers report April 16th in the journal Cell Reports. The... more
This could be a crucial year for the powerful gene-editing technique CRISPR as researchers start testing it in patients to treat diseases such as... more
Scientists have discovered that the cause of cancer is “written” within the DNA of tumors, a finding that could help doctors to decide on the best... more
The powerful gene-editing technique is moving out of the lab and into the clinic. Trials will use CRISPR to try to treat a variety of diseases, ranging from cancer and... more
A new study from BC Children's Hospital, the University of British Columbia (UBC) and an international team of researchers published in the New England Journal of Medicine is the first to identify a rarely-seen... more
Liver cells have an innate resistance to RNA viral infections like hepatitis A, dengue and Zika thanks to a protein called IRF1, according to researchers at the University of North... more
11,000 people are predicted to die from acute myeloid leukemia in 2019, according to the American Cancer Society. The cancer starts in the bone marrow. There, mutated genes fail to... more
A consortium of researchers led by Georgetown Lombardi Comprehensive Cancer Center investigators have completed the largest analysis of a new gene fusion... more
Scientists in Cambridge and London have developed a catalog of DNA mutation 'fingerprints' that could help doctors pinpoint the environmental culprit responsible for a... more
When it comes to stem cell management, all flowering plants work to maintain the same status quo. Researchers have now identified the various strategies plants use to preserve... more
A new study is the first to identify a rarely-seen type of DNA mutation as the cause of an inherited metabolic disorder. Inherited metabolic disorders -- where the body can't break down specific nutrients from food... more
The gene most often associated with risk of Alzheimer's Disease impacts sleep depending on gender and the severity of Alzheimer's in a patient, suggests a study... more
Pollen genes mutate naturally in only some strains of corn, according to Rutgers-led research that helps explain the genetic instability in certain strains and may lead to better... more
Hematology researchers have further refined how a treatment currently used on an urgent basis to control bleeding in hemophilia patients holds promise as a preventive treatment as well.... more
Researchers hoping to better interpret data from the detection of gravitational waves generated by the collision of binary black holes are turning to the public for... more
A team of investigators has discovered a new, more powerful variant on an antimicrobial resistance gene common among Staphylococcus species. The gene protects the... more
Scientists have succeeded in incorporating a light-controlled switch into a molecule used by bacteria for quorum sensing -- a process by which bacteria communicate and subsequently control different... more
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