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New liquid biopsy test confirms remission in patients with HPV-associated oropharyngeal cancer
NEWS MEDICAL A highly sensitive blood test that detects minute traces of cancer-specific DNA has been shown to accurately determine whether patients with HPV-related oropharyngeal squamous... 3 hours
Innovative computer software sheds new light on genetic processes underlying deadly diseases
NEWS MEDICAL Innovative computer software developed by University of Leicester scientists is shedding new light on the genetic makeup of deadly pathogens responsible for meningitis and... 4 hours
Why are U.S. neuroscientists clamoring for marmosets?
Science Magazine Genetically engineered monkey models spark new projects—and raise ethical questions 4 hours
Tortoise evolution: How did they become so big?
SCIENCE DAILY The evolution of giant tortoise might not be linked to islands, as had been previously thought. In a first-of-its-kind study, researchers present the most comprehensive family tree of extinct and extant tortoises... 4 hours
How a single mutation can devastate cellular function
NEWS MEDICAL A scientist has shown how a single mutation in a protein found in astrocytes reproduces fibrous globs that devastate cellular function. 6 hours
Ultra-close stars discovered inside a planetary nebula
PHYS.ORG An international team of astronomers have discovered two stars in a binary pair that complete an orbit around each other in a little over three hours, residing in the planetary nebula M3-1. Remarkably, the... 7 hours
More antimicrobial resistance in pigs than in broilers in Europe
PHYS.ORG In the largest metagenomics study of production animals to date, the Technical University of Denmark has found more antimicrobial resistance in pigs than in broilers, but a greater... 8 hours
Revolutionising the Nile tilapia breeding program using DNA
PHYS.ORG Tilapia, a tropical fish, is an important aquaculture species farmed in more than 100 countries, and after carp is the second most important aquaculture species in the world accounting for 7.4 percent... 9 hours
Studying the hotbed of horizontal gene transfers
PHYS.ORG For over 200,000 years, humans and their gut microbiomes have coevolved into some of the most complex collections of living organisms on the planet. But as human lifestyles vary from the urban to rural,... 10 hours
New type of molecule shows early promise against treatment-resistant prostate cancer
NEWS MEDICAL A new type of molecule blocks the action of genes that drive the growth of therapy-resistant prostate cancer, a new study finds. 11 hours
New discovery may lead to better treatment options for pancreatic cancer patients
NEWS MEDICAL Pancreatic cancer is one of the most difficult cancers to treat and is a leading cause of cancer-related deaths. Now, Sidney Kimmel Cancer Center... 16 hours
New approach may lead to better diagnostic techniques for autoimmune disorders
NEWS MEDICAL If we really want to know how our body's cells work - or don't work, in the case of disease - we might need to look... 16 hours
Researchers identify common genetic connection in lung conditions
NEWS MEDICAL An international research team led by members of the University of Colorado School of Medicine faculty has identified a genetic connection between rheumatoid arthritis-associated interstitial lung disease and idiopathic pulmonary fibrosis. 18 hours
Researchers wake-up DNA from soil bacteria to discover novel acid antibiotic
SCIENCE DAILY Scleric Acid has been discovered by capturing and engineering a DNA fragment from soil bacteria Streptomyces sclerotialus, and could help fight bacterial infections. 1 day
Common genetic link in lung ailments
SCIENCE DAILY An international research team has identified a genetic connection between rheumatoid arthritis-associated interstitial lung disease and idiopathic pulmonary fibrosis. 1 day
Genetic profile for a section of Aspergillus fungi
SCIENCE DAILY Aspergillus is an important fungal genus, with roles in agriculture, biotechnology, human health, enzyme production and food fermentation. Scientists now present the first large analysis of an Aspergillus fungal subgroup, section Nigri. 1 day
Losing control of gene activity in Alzheimer's disease
SCIENCE DAILY Pioneering research into the mechanisms controlling gene activity in the brain could hold the key to understanding Alzheimer's disease and might help identify effective treatments in the future. 1 day
New tool gives deeper understanding of glioblastoma
SCIENCE DAILY Researchers have developed a new tool to study genetic 'switches' active in glioblastoma tumors that drive growth of the cancer. In a new article, they identified key switches in different types of tumors, including... 1 day
Study: Targeting specific genomic mutation in breast cancer improves survival
NEWS MEDICAL Targeting a common mutation in patients with hormone receptor positive (HR+) HER2 negative (HER2-) advanced breast cancer with the alpha-specific phosphatidylinositol-3-kinase (PI3K) inhibitor alpelisib significantly improves progression-free survival,... 1 day
Medical News Today: Scientists create genetic score that predicts lifespan
MNT New research uncovers 21 genetic variants that are associated with changes in lifespan and presents a genetic score that predicts a person's survival. 1 day
Studying the hotbed of horizontal gene transfers
MIT Global Microbiome Conservancy research reveals surprising new insights into human gut microbiomes. 1 day
Spotlighting differences in closely-related species
PHYS.ORG There are millions of fungal species, and those few hundred found in the Aspergillus genus play important roles in areas ranging from industrial production to agricultural plant pathogens. Reported October 22, 2018, in Nature Genetics, a team led... 1 day
Cellular trash cans reveal the roles of proteins in disease
PHYS.ORG If we really want to know how our body's cells work—or don't work, in the case of disease—we might need to look beyond their genes and even beyond... 1 day
Researchers wake-up DNA from soil bacteria to discover novel acid antibiotic
PHYS.ORG Scleric Acid has been discovered by capturing and engineering a DNA fragment from soil bacteria Streptomyces sclerotialus, and could help fight bacterial infections—by researchers at the... 1 day
Understanding architecture of cancer-linked BAF protein complexes provides insight into disease
PHYS.ORG In 2013, Broad Institute member Cigall Kadoch, then a postdoctoral researcher at Stanford University, discovered that approximately 20 percent of all human cancers involve mutations in... 1 day
On This Day in Space! Oct. 22, 1992: Gene Roddenberry's Ashes Launch into Space
SPACE.COM On Oct. 22, 1992, the space shuttle Columbia launched into space with the ashes of Gene Roddenberry, the creator of... 1 day
Pando, World’s Largest Single Organism, is Shrinking
SCI-NEWS.COM A team of researchers from Utah State University has conducted the first complete assessment of the Pando aspen clone — the largest... 1 day
IDT to demonstrate CRISPR expertise at European-focused events
NEWS MEDICAL As an advocate for the genomics age, Integrated DNA Technologies (IDT), will showcase its renowned CRISPR expertise at a series of European-focused events. 2 days
Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas
NEWS MEDICAL Merck, known as MSD outside the United States and Canada, today announced the first presentation of preliminary data from a... 2 days
Maintenance therapy with olaparib improves progression-free survival in advanced ovarian cancer patients
NEWS MEDICAL Two-year maintenance therapy with olaparib, a PARP (poly ADP ribose polymerase) inhibitor, olaparib, led to a substantial, unprecedented improvement in progression-free survival (PFS) in... 2 days
Labrador retrievers at risk of various health problems
PHYS.ORG Labrador retrievers, the second most popular dog breed in the UK, are vulnerable to a number of health conditions, according to a study published in the open access journal Canine Genetics and... 2 days
AstraZeneca's Lynparza shown to put brakes on ovarian cancer
REUTERS An AstraZeneca drug that blocks a cancer cell's ability to repair its genetic code greatly reduced the risk... 2 days
Medical News Today: Cancer: Even healthy tissue is 'riddled with mutations'
MNT A new study charts the slow build-up of genetic mutations. The researchers are surprised to find that even healthy human tissue carries many mutants. 2 days
Roche takes on Loxo, Bayer in gene-defined cancer class
REUTERS Roche's entrectinib cancer pill was shown to shrink tumors in 57 percent of patients within a group that... 2 days
Giant study links DNA variants to same-sex behavior
Science Magazine People who reported having at least one same-sex partner more likely to share certain genetic markers 3 days
ApoE4 gene linked with chronic inflammation increases risk for Alzheimer's disease
NEWS MEDICAL While it is widely shown that possessing the ApoE4 gene is the major genetic risk factor of Alzheimer's disease, not all ApoE4 carriers develop AD. 3 days
New, large sequence panel enables population genetics research in Africa
SCIENCE DAILY Geneticists have assembled the largest sets of African genomic data available to date, creating a resource that will help researchers understand the genetic structure of Africa as well... 3 days
Genetic study improves lifespan predictions and scientific understanding of aging
SCIENCE DAILY By studying the effect of genetic variations on lifespan across the human genome, researchers have devised a way to estimate whether an individual can expect to live longer... 3 days
Does herpes cause Alzheimer's?
SCIENCE DAILY Herpes is the dreaded 'gift that keeps on giving'. But could it also be taking our memories? Decades of research show a striking correlation between Alzheimer's disease risk and infection with Herpes Simplex Virus 1 (HSV1) in people carrying a... 3 days
A single missing gene leads to miscarriage
SCIENCE DAILY A single gene of the mother plays such a crucial role in the development of the placenta that its dysfunction leads to miscarriages. Researchers have observed this in so-called knockout mice that were specifically... 3 days
Genetic behavior reveals cause of death in poplars essential to ecosystems, industry
SCIENCE DAILY Scientists studying a valuable, but vulnerable, species of poplar have identified the genetic mechanism responsible for the species' inability to resist a pervasive and... 3 days
Novartis drug cut death risk by 35 percent in gene mutation breast cancer
REUTERS An experimental cancer drug that Novartis hopes will raise the... 3 days
DNA differences are linked to having same-sex sexual partners
SCIENCE-NEWS Genetic differences are associated with choosing same-sex partners in both men and women. 3 days
Brazil recovers ancient human fossil fragments from burnt Rio museum
PHYS.ORG Brazilian officials said Friday they have recovered pieces of a 12,000-year-old fossil of a neolithic woman that was among the prized artifacts in Rio de Janeiro's burnt down... 4 days
Bug guts shed light on Central America Chagas disease
SCIENCE DAILY In Central America, Chagas disease, or American trypanosomiasis, is spread by the 'kissing bug' Triatoma dimidiata. By collecting DNA from the guts of these bugs, researchers reporting in PLOS Neglected... 4 days
A tailormade drug developed in record time may save girl from fatal brain disease
Science Magazine DNA-based therapy for Batten disease shows promise of personalized medicine 4 days
MS genes formerly missing-in-action have been found
SCIENCE DAILY Scientists have cracked a tough nut in multiple sclerosis: where are all the genes? 4 days
Making gene therapy delivery safer and more efficient
SCIENCE DAILY Viral vectors used to deliver gene therapies undergo spontaneous changes during manufacturing which affects their structure and function. As gene therapy approaches become more common for treating disease, managing consistency of the... 4 days
Advanced sequencing technology provides new insights into human mitochondrial diseases
SCIENCE DAILY Researchers have for the first time been able to investigate the abundance and methyl modifications of all mitochondrial tRNAs in patients suffering from one of the most common... 4 days
New therapies pack a triple-drug punch to treat cystic fibrosis
SCIENCE-NEWS In testing, a triple-drug therapy significantly improved lung function in cystic fibrosis patients with the most common disease-causing mutation. 4 days
By Middle Age, Healthy People Have Way More Cancer-Causing Mutations Than We Thought
LIVE SCIENCE Our cells change over time. Apparently, a lot. 4 days
Dysfunction of single gene leads to miscarriages
NEWS MEDICAL A single gene of the mother plays such a crucial role in the development of the placenta that its dysfunction leads to miscarriages. 4 days
New data tool can help scientists use limited funds to protect the greatest number of endangered species
PHYS.ORG VIDEO A large majority of Americans strongly support the goal of preventing the extinction of... 4 days
Genetic behavior reveals cause of death in poplars essential to ecosystems, industry
PHYS.ORG Scientists studying a valuable, but vulnerable, species of poplar have identified the genetic mechanism responsible for the species' inability to resist a pervasive and... 4 days
Advanced sequencing technology provides new insights into human mitochondrial diseases
PHYS.ORG The ability to translate the genetic code into proteins is an essential step in all living organisms. A cornerstone of this molecular process is the ability of transfer... 4 days
Survey finds high prevalence of HTLV-1 infection among teens and adults in Gabon
NEWS MEDICAL A study published in PLOS Neglected Tropical Diseases, by Mirdad Kazanji, of the Centre International de Recherches Medicales de Franceville in Gabon,... 4 days
Medical News Today: What are 10 risk factors for rheumatoid arthritis?
MNT The exact causes of rheumatoid arthritis are unclear, but researchers have identified several risk factors. These range from genetic predispositions to gum disease. Learn more here. 4 days
Sweat bees are ideal for studying the genes underlying social behavior
NEWS MEDICAL Those pesky bees that come buzzing around on a muggy summer day are helping researchers reveal the genes responsible for social behaviors. 5 days
Understanding of metal-free enzymes used by bacteria could lead to new effective antibiotics
NEWS MEDICAL Some bacterial pathogens, including those that cause strep throat and pneumonia, are able to create the components necessary to replicate their DNA... 5 days
Newly developed synthetic DNA molecule may one day be used as 'vaccine' for prostate cancer
NEWS MEDICAL Researchers from City of Hope, a world-renowned comprehensive cancer center and independent biomedical research institution, have developed a... 5 days
Next-generation RNA sequencing technology sheds new light on human mitochondrial diseases
NEWS MEDICAL The ability to translate the genetic code into proteins is an essential step in all living organisms. A cornerstone of this molecular process is the ability... 5 days
Gene sequencing reveals crucial molecular aspects of Trypanosoma brucei
NEWS MEDICAL Trypanosoma brucei, which causes sleeping sickness, evades the immune system by repeatedly altering the structure of its surface coat. Sequencing of its genome and studies of its 3D genome architecture... 5 days
New DNA vaccine strategy protects mice against lethal challenge by multiple H3N2 viruses
NEWS MEDICAL Researchers developed a novel DNA influenza vaccine based on four micro-consensus antigenic regions selected to represent the diversity of seasonal H3N2 viruses... 5 days
Genetic breakthrough will aid whitebark pine conservation efforts
SCIENCE DAILY A research team for the first time developed reliable genetic markers known as nuclear microsatellites for the whitebark pine, a discovery that could improve the tree's prospects for survival. Whitebark pine, which... 5 days
Mutant cells in the esophagus, and protecting farmers from dangerous pesticide exposure
Science Magazine On this week’s show: what we can learn from non–cancer-causing mutations in the esophagus, and how to protect farmers from dangerous pesticide exposure 5 days
Genetic breakthrough will aid whitebark pine conservation efforts
PHYS.ORG A University of Colorado Denver-led research team for the first time developed reliable genetic markers known as nuclear microsatellites for the whitebark pine, a discovery that could improve the tree's prospects for... 5 days
Medical News Today: How do you treat a droopy eyelid?
MNT Ptosis refers to a droopy eyelid, where the upper eye area lowers downward. Causes include genetics, eye surgery, and excessive rubbing. Treatment can involve surgery, but usually for... 5 days
Asthma's effects on airways at the single cell level
SCIENCE DAILY By sequencing genetic material at a cell-by-cell level, researchers have described how type 2-high asthma affects the airways and results in mucus production with more detail than ever before. These... 5 days
Researchers propose CRISPR as influencer of low genetic diversity in deadly bacteria
PHYS.ORG Scientists at Oregon State University have shed light on the evolutionary history of a soil-borne bacteria that is so dangerous to grazing animals it... 5 days
The opium poppy genome and morphinan production
Science Magazine Morphinan-based painkillers are derived from opium poppy (Papaver somniferum L.). We report a draft of the opium poppy genome, with 2.72 gigabases assembled into 11 chromosomes with contig N50 and scaffold N50 of 1.77... 5 days
DNGR-1 in dendritic cells limits tissue damage by dampening neutrophil recruitment
Science Magazine Host injury triggers feedback mechanisms that limit tissue damage. Conventional type 1 dendritic cells (cDC1s) express dendritic cell natural killer lectin group receptor-1 (DNGR-1), encoded by... 5 days
Chemists find a recipe that may have jump-started life on Earth
Science Magazine New sequence of reactions could have created all four RNA bases at once 5 days
Somatic mutant clones colonize the human esophagus with age
Science Magazine The extent to which cells in normal tissues accumulate mutations throughout life is poorly understood. Some mutant cells expand into clones that can be detected by genome sequencing. We mapped... 5 days
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
Science Magazine CRISPR-Cas systems provide microbes with adaptive immunity to infectious nucleic acids and are widely employed as genome editing tools. These tools utilize RNA-guided Cas proteins whose large size (950–1400 amino acids) has been considered... 5 days
New tool helps align investment with objectives in biodiversity conservation
PHYS.ORG One of the balancing acts faced by conservation agencies is how to conserve and protect as many species as possible from extinction with limited funding and finite resources.... 5 days
Smallest life forms have smallest working CRISPR system
PHYS.ORG An ancient group of microbes that contains some of the smallest life forms on Earth also has the smallest CRISPR gene-editing machinery discovered to date. 5 days
Bee social or buzz off: Study links genes to social behaviors, including autism
SCIENCE DAILY A new study found that the social lives of sweat bees -- named for their attraction to perspiration -- are linked to... 5 days
Environmental associations with genes may yield opportunities for precision medicine
SCIENCE DAILY A new approach to genetic analysis finds associations between environmental factors and pharmacogenes -- genes associated with a person's response to drugs -- sparking ideas for new research... 5 days
New file type improves genomic data sharing while maintaining participant privacy
SCIENCE DAILY Based on an analysis of data leakages and opportunities to prevent the potential misuse of genetic information, researchers have developed a new file format for functional... 5 days
Study links genes to social behaviors, including autism
PHYS.ORG Those pesky bees that come buzzing around on a muggy summer day are helping researchers reveal the genes responsible for social behaviors. A new study published this week found that the social... 5 days
Pathogens may evade immune response with metal-free enzyme required for DNA replication
SCIENCE DAILY A new study shows that some bacterial pathogens, including those that cause strep throat and pneumonia, are able to create the components necessary to... 5 days
Big-picture approach to understanding cancer will speed new treatments
SCIENCE DAILY The new approach lets scientists examine the cumulative effect of multiple gene mutations, providing a much more complete picture of cancers' causes. 5 days
Pathogens may evade immune response with metal-free enzyme required for DNA replication
PHYS.ORG Some bacterial pathogens, including those that cause strep throat and pneumonia, are able to create the components necessary to replicate their DNA without the... 5 days
University choice and achievement partly down to DNA
SCIENCE DAILY Research has shown for the first time that genetics plays a significant role in whether young adults choose to go to university, which university they choose to attend and how well they... 5 days
Nanocages in the lab and in the computer: how DNA-based dendrimers transport nanoparticles
PHYS.ORG How to create nanocages, i.e., robust and stable objects with regular voids and tunable properties? Short segments of DNA molecules are perfect... 5 days
Imec's elPrep software significantly speeds up genome sequencing analysis
PHYS.ORG This week at ITF Health 2018, imec, the world-leading research and innovation hub in nanoelectronics and digital technologies, showcases elPrep 4.0, a powerful software tool to speed up human DNA... 5 days
Did eating starchy foods give humans an evolutionary advantage?
PHYS.ORG Gene AMY1, which kickstarts digestion of starch in the mouth, is associated with blood glucose levels and digestion of carbohydrates, with implications for understanding human evolutionary biology and the gut... 5 days
Gene-edited zebrafish models take disease research to the next level
SCIENCE DAILY The potent combination of CRISPR/Cas9 and zebrafish as a model organism offers enormous potential for research into human diseases caused by point mutations. Three new articles use zebrafish... 5 days
Did eating starchy foods give humans an evolutionary advantage?
SCIENCE DAILY Gene AMY1, which kickstarts digestion of starch in the mouth, is associated with blood glucose levels and digestion of carbohydrates, with implications for understanding human evolutionary biology and the gut... 5 days
New approach for controlling dengue fever and Zika virus
SCIENCE DAILY To be able to reproduce and become effective disease carriers, mosquitoes must first attain optimal body size and nutritional status. A pair of researchers have succeeded in using CRISPR-Cas9, a... 5 days
University choice and achievement partly down to DNA
PHYS.ORG Research from King's College London has shown for the first time that genetics plays a significant role in whether young adults choose to go to university, which university they choose to attend... 5 days
Genetically modifying zebrafish provides numerous, highly accurate disease models
NEWS MEDICAL Research published today describes how zebrafish can be genetically engineered to produce more accurate models of human disease. 5 days
Is this bee solitary or social? The answer may depend on an autism-linked gene
Science Magazine Change in gene activity leads loners to keep their young around 5 days
Sleeping Beauty technique helps identify genes responsible for NAFLD-associated liver cancer
NEWS MEDICAL With an estimated twenty-thousand protein-coding genes in the human genome, pinpointing a specific gene or pathway responsible for a particular disease can be like finding a... 6 days
Genome sequencing found feasible and informative for pediatric cancer treatment
SCIENCE DAILY Comprehensive genetic testing of tumors and non-cancerous tissue from pediatric cancer patients is a feasible and clinically useful approach that can guide patient care, according to new findings. 6 days
Combining genetic and sun exposure data improves skin cancer risk estimates
SCIENCE DAILY By combining data on individuals' lifetime sun exposure and their genetics, researchers can generate improved predictions of their risk of skin cancer. 6 days
Ancient Andean genomes show distinct adaptations to farming and altitude
PHYS.ORG Ancient populations in the Andes of Peru adapted to their high-altitude environment and the introduction of agriculture in ways distinct from other global populations that faced similar circumstances,... 6 days
Largest autism sequencing study to date yields 102 genes associated with ASD
SCIENCE DAILY In the largest genetic sequencing study of autism spectrum disorder (ASD) to date, researchers have identified 102 genes associated with ASD, and report significant... 6 days
Not Just For Cows Anymore: New Cottonseed Is Safe For People To Eat
NPR Cottonseed is full of protein but toxic to humans and most animals. The USDA has approved a genetically engineered cotton with edible... 6 days
One of the World's Oldest and Largest Organisms Is Dying, and It's Mostly Our Fault
LIVE SCIENCE The aspen clone in Utah is on the decline 6 days
New data tool can help scientists use limited funds to protect the greatest number of endangered species
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