Biologic age, a DNA-based estimate of a person's age, is associated with future development of breast cancer, according to scientists. Biologic age was determined by measuring DNA methylation, a chemical... more
One third of hypertrophic cardiomyopathy cases in Finland are caused by one of the four major mutations, a new study shows. Overall, 40 percent of patients carried a specific or a likely mutation causing... more
Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have figured out a better way to deliver a DNA editing tool to shorten the presence of the... more
Patients with Duchenne muscular dystrophy (DMD) have few treatment options. Medications currently available or in development either target only a... more
The number of papers reporting new protein-function discoveries in 2017 declined by two-thirds compared with 2000 output, according to research led by A*STAR. more
The human genome contains an estimated 20,000 genes coding for proteins. The proteins are the body's "workers," tasked with performing specific functions that are key to survival. Despite their importance, there is... more
Researchers at the University of Helsinki uncovered the mechanisms for a novel cellular stress response arising from the toxicity of newly synthesized proteins. Activation of the stress response... more
Bacteria in the gut do far more than help digest food in the stomachs of their hosts, they can also tell the genes in their mammalian hosts what to do. more
Ben-Gurion University of the Negev researchers have found that the age puberty hits is based on the gap between the parents' and child's ultimate height, not... more
Skin cells taken from patients with a rare genetic disorder are up to ten times more sensitive to damage from ultraviolet A radiation in laboratory tests, than those from a... more
Tel Aviv University researchers have developed a new blood test for genetic disorders that may allow parents to learn about the health of their baby as early as 11 weeks into pregnancy. more
Patients with Duchenne muscular dystrophy (DMD) have few treatment options. Medications currently available or in development either target only a... more
Using high-throughput genetic sequencing methods, scientists have created the first cellular atlas of the primate retina, an important foundation for researchers to build on as they seek to understand how vision works in primates, including humans, and how vision can... more
In a research breakthrough funded by NASA, scientists have synthesized a molecular system that, like DNA, can store and transmit information. This unprecedented feat suggests there could be... more
How do fruit flies grow their wings? Scientists discovered a surprising answer that could one day help diagnose and treat human genetic diseases. Even when scientists manipulate cells... more
Skin cells taken from patients with a rare genetic disorder are up to ten times more sensitive to damage from ultraviolet A (AVA) radiation in laboratory tests, than those from a healthy... more
Researchers from the University of Colorado Anschutz Medical Campus, in collaboration with several other institutions, have discovered a genetic defect linked to Biliary atresia, the most common pediatric cause of end-stage liver... more
Scientists have obtained more precise dates for the Deccan Traps volcanic lava flows, linking peak activity more closely to the asteroid or comet impact 66 million years ago... more
We report DNA- and RNA-like systems built from eight nucleotide "letters" (hence the name "hachimoji") that form four orthogonal pairs. These synthetic systems meet the structural... more
Potassium (K+) channels have been evolutionarily tuned for activation by diverse biological stimuli, and pharmacological activation is thought to target... more
Temporal correlation between some continental flood basalt eruptions and mass extinctions has been proposed to indicate causality, with eruptive volatile... more
Chloroplasts contain thousands of nucleus-encoded proteins that are imported from the cytosol by translocases in the chloroplast envelope membranes. Proteolytic regulation of the translocases is critically important, but little is known about the underlying mechanisms. We... more
UC Berkeley scientists have obtained more precise dates for the Deccan Traps volcanic lava flows, linking peak activity more closely to the asteroid or comet impact 66 million... more
In the global quest to develop practical computing and communications devices based on the principles of quantum physics, one potentially useful component has proved elusive: a source of individual particles of light with perfectly... more
Mechanical engineers are working on genetically engineering and optimizing E. coli bacteria to produce bioproducts, like biodiesel, in a cost-effective manner. more
Skin cells taken from patients with a rare genetic disorder are up to ten times more sensitive to damage from ultraviolet A (AVA) radiation in laboratory... more
The idea that children inherit half of their DNA from each parent is a central tenet of modern genetics. But a team led by KAUST's Christian Frøkjær-Jensen has re-engineered this heredity pattern in roundworms, a commonly... more
How do fruit flies grow their wings? Rutgers scientists discovered a surprising answer that could one day help diagnose and treat human genetic diseases. more
Although white-nose syndrome (WNS) has pushed some bat populations to extinction, researchers have found that higher fat stores are helping some little brown bats to survive this deadly... more
A small pilot clinical study at the National Eye Institute suggests that the drug nitisinone increases melanin production in some people with oculocutaneous albinism type 1B, a rare genetic disease... more
Thermo Fisher Scientific Inc. says it will no longer sell or service genetic sequencers in China's mostly Muslim region of Xinjiang following criticism that they were... more
The first time someone took note of Coniochaeta pulveracea was more than two hundred years ago, when the South African-born mycologist Dr Christiaan Hendrik Persoon mentioned it in his 1797 book on the classification of fungi.... more
Scientists have managed to restore hearing in an adult mouse model of DFNB9 deafness -- a hearing disorder that represents one of the most frequent cases of congenital genetic deafness. Individuals with... more
A new observation highlights the importance of previously unstudied mutations that arises early in bnAbs, giving the antibodies the flexibility to adapt to changes in the virus's outer... more
Researchers have discovered a DNA modification that enhances our ability to extinguish fear. The findings could help guide the development of new treatments for fear-related anxiety disorders. Professor... more
A team of biologists, physicists and mathematical modellers have studied the genetic activity of over 100,000 embryonic cells to establish the molecular blueprint of mouse early embryo development. This new research provides... more
Female cells randomly and permanently shut off one of the X chromosomes during embryonic development through a process called X chromosome inactivation, or XCI. Just how XCI occurs... more
A small pilot clinical study suggests that the drug nitisinone increases melanin production in some people with oculocutaneous albinism type 1B (OCA-1B), a rare genetic disease that causes pale skin and hair and poor... more
Marine sediments host an unexpectedly large microbial biosphere, suggesting unique microbial mechanisms for surviving burial and slow metabolic turnover. Although dormancy is... more
Nonhepatic delivery of small interfering RNAs (siRNAs) remains a challenge for development of RNA interference–based therapeutics. We report a noncationic vector wherein linear poly(ethylene... more
A team of biologists, physicists and mathematical modellers in Cambridge have studied the genetic activity of over 100,000 embryonic cells to establish the molecular blueprint of mouse early embryo development. This new... more
Aggressiveness among animals may increase the longer individuals live together in stable groups. The study used the Amazon molly, a naturally clonal fish species that produces genetically identical individuals to isolate the effects of familiarity on behavior. more
In a study of mice and human brain tumors researchers searched for new treatments by exploring the reasons why some patients with gliomas live remarkably longer than others. The results suggested that certain patients'... more
As cities get bigger and cover more land, the need to make space for wildlife – including insects – in urban areas has become more pressing. Research has... more
Scientists from the Centro Nacional de Investigación sobre la Evolución Humana (CENIEH) have published a paper in the International Journal of Paleopathology that describes the first case of... more
A relatively unknown fungus, accidentally found growing on an Acacia tree in the Northern Cape, has emerged as a voracious wood-munching organism with enormous potential in industries based on renewable resources. more
Fungal diseases collectively termed "powdery mildew" afflict a broad range of plant species, including agriculturally relevant cereals such as barley, and result in significant reductions in crop yield.... more
Is evolution predictable? What are the mechanisms that allow different fish to respond to the same environmental challenge in slightly different ways? When the same jaw bones and muscles change... more
La hipertensión puede derivar en una cardiopatía, un ACV y muerte, lo que la convierte en la mayor preocupación a nivel global. Muchos factores de riesgo pueden aumentar las oportunidades de que... more
El VIH ataca a las células inmunes y se transmite mediante los fluidos corporales, mientras que el SIDA es una enfermedad que puede emerger de una etapa avanzada por infección... more
Infórmese sobre esta enfermedad contagiosa que se esparce mediante el aire por las bacterias. Puede ser mortal y afectar a cualquier persona en cualquier parte del... more
Las manchas blancas en la piel generalmente surgen cuando las proteínas cutáneas o las células muertas quedan atrapadas debajo de la superficie de la piel. more
El 70% de las mujeres sufre dolor en una o ambas mamas y solo el 15% requiere tratamiento. Es muy común en las más jóvenes y durante la menstruación. Se... more
The insects were created, using CRISPR, to carry a powerful "gene drive." The mosquitoes could provide a potent weapon against malaria, but they raise fears about unpredictable environmental effects. more
A new antimicrobial-resistance gene, VCC-1, a ß-lactamase gene, has been discovered in benign close relatives of virulent Vibrio cholerae, which causes cholera. Now, a team of Canadian researchers... more
Aging is a leading risk factor for a number of debilitating conditions, including heart disease, cancer and Alzheimer's disease, to name a few. This makes the need for anti-aging therapies all the... more
Like many other medical conditions, the mechanism of multiple sclerosis remains an enigma--a puzzle composed of complex genetic and environmental factors. A key piece to this puzzle is... more
By studying fish raised in aquaculture, researchers have shed new light on the mechanisms by which antibiotic resistance genes are transferred between bacteria. According to their study, those mechanisms are... more
According to a new study, birch pollen allergen immunotherapy modifies the gene expression and microbiome profile of the nasal epithelium to correspond to those of healthy controls. more
A new antimicrobial-resistance gene, VCC-1, a beta-lactamase gene, has been discovered in benign close relatives of virulent Vibrio cholerae, which causes cholera. Now, a team of Canadian researchers has found a way to block... more
In collaboration with the universities of Miami, Columbia and San Francisco, scientists from the Institut Pasteur, Inserm, CNRS, Collège de France, Sorbonne University and the University of Clermont... more
Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function... more
Researchers have developed a new gene therapy to help decelerate the aging process. The findings highlight a novel CRISPR/Cas9 genome-editing therapy that... more
The Extinction Rebellion, a network of climate activists who use civil disobedience to spotlight inaction on global warming, is rooted in the conviction that humanity has dug its own grave... more
Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function... more
An international team of more than 200 astronomers from 18 countries has published the first phase of a major new radio sky survey at unprecedented sensitivity using the... more
Australia officially declared a Great Barrier Reef rodent extinct on Tuesday, making it the first mammal believed to have been killed off by human-induced climate change. more
Researchers have reversed symptoms of depression, such as anhedonia and behavioral despair, in male mice with a drug that activates a gene they call SIRT1. more
Researchers have reversed symptoms of depression, such as anhedonia and behavioral despair, in male mice with a drug that activates a gene they call SIRT1. more
From fathers to children, the delivery of hereditary information requires the careful packing of DNA in sperm. But just how nature packages this DNA... more
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