Genetics
From the tiny testes of flies, new insight into how genes arise  SCIENCE DAILY · 1 day
A common birthplace of new genes, the male testes are a hotspot for biological innovation. Within these organs, scientists have found a trove of... more
From the tiny testes of flies, new insight into how genes arise  PHYS.ORG · 1 day
In the battle of the sexes, males appear to have the innovative edge—from a genetic standpoint, at least. Scientists are finding that the testes... more
IDT launches high quality, ready-to-use custom oligo pools  NEWS MEDICAL · 2 days
Continuing its mission to advance biological research worldwide, Integrated DNA Technologies has launched oPools Oligo Pools – ready-to-use pools of high quality DNA oligonucleotides (oligos) up to 350 nucleotides in length. more
Numbers count in the genetics of moles and melanomas  SCIENCE DAILY · 2 days
Scientists have identified a way to help dermatologists determine a patient's risk of developing melanoma. more
Genetic study suggests humans, not Ice Age, killed off European cave bears  PHYS.ORG · 2 days
A team of researchers affiliated with multiple institutions across Europe has found evidence that suggests humans were responsible for the extinction of cave bears... more
Lizards from cold climates may face rapid extinctions in next 60 years, study shows  PHYS.ORG · 2 days
Lizards that produce live young are significantly more likely to be driven to extinction through climate change than those that... more
Gene regulation behind the choice of the correct receptor for olfaction  SCIENCE DAILY · 2 days
Scientists have uncovered the genetics behind two distinct types of olfactory sensory neurons; the so called 'class I olfactory neurons' that has persisted from aquatic to... more
Influenza A virus host range restricted by dysregulated expression of M gene segment  NEWS MEDICAL · 2 days
The host range of the influenza A virus is restricted by dysregulated expression of the M viral gene segment, according to a... more
Advanced method to accurately detect low-level somatic mutation in intractable epilepsy  NEWS MEDICAL · 2 days
KAIST medical scientists have developed an advanced method for perfectly detecting low-level somatic mutation in patients with intractable epilepsy. Their study showed that deep sequencing replicates... more
Gentle giraffes threatened with 'silent extinction'  PHYS.ORG · 2 days
For most of his life as a Samburu warrior, Lesaiton Lengoloni thought nothing of hunting giraffes, the graceful giants so common a feature of the Kenyan plains where he roamed. more
Advanced method to accurately detect low-level somatic mutation in intractable epilepsyc  NEWS MEDICAL · 2 days
KAIST medical scientists have developed an advanced method for perfectly detecting low-level somatic mutation in patients with intractable epilepsy. Their study showed that deep sequencing replicates... more
Researchers gain new insights into the mechanism of vaccine-induced T cell immunity  NEWS MEDICAL · 2 days
A team led by the Walter Reed Army Institute of Research has gained new insights into the mechanism of vaccine-induced T cell immunity utilizing... more
Genetic redundancy aids competition among bacteria in symbiosis with squid  SCIENCE DAILY · 2 days
The molecular mechanism used by many bacteria to kill neighboring cells has redundancy built into its genetic makeup, which could allow for the mechanism to be expressed in... more
Gleevec (imatinib)  MNT · 2 days
Gleevec (imatinib) is a brand-name prescription medication. It’s used to treat certain types of blood cancers, including Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML). It’s also used to treat certain types of skin cancer and gastrointestinal cancer. Learn about side... more
Genetic redundancy aids competition among bacteria in symbiosis with squid  PHYS.ORG · 2 days
The molecular mechanism used by many bacteria to kill neighboring cells has redundancy built into its genetic makeup, which could allow for the mechanism to be expressed in... more
Countries push to protect sharks, rays  PHYS.ORG · 2 days
Dozens of countries will push at a global meeting for regulations on trade in 18 types of shark and ray, with conservationists warning Thursday of looming extinction for many species. more
Extinct Caribbean bird yields DNA after 2,500 years in watery grave  SCIENCE DAILY · 3 days
Scientists have recovered the first genetic data from an extinct bird in the Caribbean, thanks to the remarkably preserved bones of a Creighton's caracara from a... more
Extinct Caribbean bird yields DNA after 2,500 years in watery grave  PHYS.ORG · 3 days
Scientists have recovered the first genetic data from an extinct bird in the Caribbean, thanks to the remarkably preserved bones of a Creighton's caracara from a... more
Drug interaction research: Evolution clues  SCIENCE DAILY · 3 days
A new article has shown that a key biological component in the communication system of the nematode C. Elegans can be repurposed to take on a different job,. This critical finding about the workings of evolution could one... more
Expression of M gene segment of influenza A virus determines host range  SCIENCE DAILY · 3 days
The host range of the influenza A virus (IAV) is restricted by dysregulated expression of the M viral gene segment, according to a new... more
Gene linked to physical and intellectual disabilities identified  SCIENCE DAILY · 3 days
Modern science and data sharing converged to underpin a study that identified a gene associated with a rare condition that results in physical and intellectual disabilities of children. The results suggest that... more
Genetic behavioral screen identifies an orphan anti-opioid system  Science Magazine · 3 days
Opioids target the μ-opioid receptor (MOR) to produce unrivaled pain management but their addictive properties can lead to severe abuse. We developed a whole animal behavioral platform for unbiased discovery of genes... more
Mitochondria--Striking a balance between host and endosymbiont  Science Magazine · 3 days
Mitochondria are organelles with their own genome that arose from α-proteobacteria living within single-celled Archaea more than a billion years ago. This step of endosymbiosis offered tremendous opportunities for energy production and metabolism and... more
Active cell migration is critical for steady-state epithelial turnover in the gut  Science Magazine · 3 days
Steady-state turnover is a hallmark of epithelial tissues throughout adult life. Intestinal epithelial turnover is marked by continuous cell migration, which is assumed to... more
Teosinte ligule allele narrows plant architecture and enhances high-density maize yields  Science Magazine · 3 days
Increased planting densities have boosted maize yields. Upright plant architecture facilitates dense planting. Here, we cloned UPA1 (Upright Plant Architecture1) and UPA2, two quantitative trait loci... more
Immune cells drive gallstone formation  SCIENCE DAILY · 3 days
Sticky meshworks of DNA and proteins extruded by white blood cells called neutrophils act as the glue that binds together calcium and cholesterol crystals during gallstone formation, researchers report. Both genetic and pharmacological approaches that inhibited the formation... more
Mutations linked to familial pancreatic cancer  SCIENCE DAILY · 3 days
A new study finds genetic mutations associated with hereditary forms of pancreatic cancer and mechanism by which these mutations may contribute to the development of tumors. more
How cells override genetic changes  SCIENCE DAILY · 3 days
A new discovery could lead researchers to a more effective way to treat pancreatic cancer. more
Tweaked CRISPR in neurons gives scientists new power to probe brain diseases  SCIENCE DAILY · 3 days
Researchers describe a technique that uses a special version of CRISPR to systematically alter the activity of genes in human neurons generated from stem... more
Machine learning reveals links between genetic factors and behavior  NEWS MEDICAL · 3 days
Researchers have used machine learning to start making links between seemingly instinctive, random behaviors and genetic factors. more
Genetic study implicates humans in demise of prehistoric cave bear  REUTERS · 3 days
Genetic research that reconstructed the past population dynamics of the cave bear, a prominent prehistoric denizen... more
Now endangered: The very act that protects wildlife  PHYS.ORG · 3 days
The Trump administration recently announced a proposal that would gut the Endangered Species Act. The news follows in the wake of a report from the United Nations earlier this year that more... more
Research: Previously unknown aspect of cell internalization during embryonic development  PHYS.ORG · 3 days
A team of researchers from Aix Marseille Université and CNRS, the Turing Centre for Living Systems, the University of Chicago and Collège de France has found a previously... more
Crocodiles Have Surprisingly Thin Tooth Enamel, Study Shows  SCI-NEWS.COM · 3 days
Crocodiles — and their plant-eating ancestors — have thin tooth enamel, a trait that is in stark contrast to humans... more
Controlled hydraulic fracturing sculpts mammalian embryos into shape  PHYS.ORG · 3 days
Hydraulic fracturing, or fracking, is a process most often associated with shale gas extraction, but a team of researchers from Institut Curie at the Sorbonne, and the Center for Interdisciplinary Research in... more
Stressed plants must have iron under control  SCIENCE DAILY · 3 days
When land plants' nutrient availability dwindles, they have to respond to this stress. Plant researchers have used available data to examine which genes plants activate in the event of stress and what these mean. more
Moderate to heavy drinking during pregnancy alters genes in newborns, mothers  SCIENCE DAILY · 3 days
Mothers who drink moderate to high levels of alcohol during pregnancy may be changing their babies' DNA, according to a new study. more
Stressed plants must have iron under control  PHYS.ORG · 3 days
When land plants' nutrient availability dwindles, they have to respond to this stress. Plant researchers at Heinrich Heine University Düsseldorf (HHU) have used available data to examine which genes plants activate in the event... more
Count and location of moles on the body influenced by genetic makeup  NEWS MEDICAL · 3 days
A study published this week in the journal Pigment Cell & Melanoma Research has found that genes have a greater influence than previously thought... more
Genetic census of the human microbiome  SCIENCE DAILY · 3 days
Scientists have analyzed the genetic repertoire of bacteria in the human mouth and gut. The effort marks the first chapter in efforts to compile a compendium of all genes in the human microbiome. Mapping the microbial... more
Genes linked to Alzheimer's risk, resilience ID'd  SCIENCE DAILY · 4 days
Scientists have identified a pair of genes that influence risk for both late-onset and early-onset Alzheimer's disease. more
BRAF inhibitors promote intermediate BRAF(V600E) conformations and binary interactions with activated RAS  Science Magazine · 4 days
Oncogenic BRAF mutations initiate tumor formation by unleashing the autoinhibited kinase conformation and promoting RAS-decoupled proliferative RAF-MEK-ERK signaling. We have engineered luciferase-based biosensors to... more
Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank  Science Magazine · 4 days
Genotype-by-environment interaction (GEI) is a fundamental component in understanding complex trait variation. However, it remains challenging to identify genetic variants with GEI... more
New drug shows encouraging survival in pancreatic cancer  SCIENCE DAILY · 4 days
A phase 1 clinical trial testing a new drug in pancreatic cancer had promising initial results, report researchers. The trial looked at AZD1775, an inhibitor designed to block an enzyme called Wee1,... more
Rapid evolution: New findings on its molecular mechanisms  PHYS.ORG · 4 days
The mechanisms by which new species arise are still not fully understood. What are the evolutionary processes that drive the evolution of new species? Evolutionary biologists traditionally assumed that geographical barriers between... more
Moles on the body largely influenced by genetics, finds new study  SCIENCE DAILY · 4 days
A new study has found that genes have a greater influence than previously thought not only on the number of moles you have but also where... more
Revolutionizing the CRISPR method  SCIENCE DAILY · 4 days
Researchers have refined the famous CRISPR-Cas method. Now, for the very first time, it is possible to modify dozens, if not hundreds, of genes in a cell simultaneously. more
Revolutionising the CRISPR method  PHYS.ORG · 4 days
Everyone's talking about CRISPR-Cas. This biotechnological method offers a relatively quick and easy way to manipulate single genes in cells, meaning they can be precisely deleted, replaced or modified. Furthermore, in recent years, researchers have also been using technologies based... more
Accurate detection of low-level somatic mutation in intractable epilepsy  SCIENCE DAILY · 4 days
Medical scientists have developed an advanced method for perfectly detecting low-level somatic mutation in patients with intractable epilepsy. Their study showed that deep sequencing replicates of major focal epilepsy genes... more
New insights into the mechanism of vaccine-induced T cell immunity  SCIENCE DAILY · 4 days
Medical researchers have gained new insights into the mechanism of vaccine-induced T cell immunity, including regulation, gene expression and metabolic pathways. This study used samples from a Phase... more
CRISPR enters its first human clinical trials  SCIENCE-NEWS · 4 days
The gene editor will be used in lab dishes in cancer and blood disorder trials, and to directly edit a gene in human eyes in a blindness therapy test. more
How to save trees: It's all about conflict resolution  PHYS.ORG · 4 days
The Madre de Dios rainforest in southeastern Peru is one of the biodiversity capitals of the world, with more species of plants and animals than almost anywhere else on the... more
Discovery of molecular mechanism behind spread of leishmania infection  NEWS MEDICAL · 4 days
Researchers from the Institut National de la Recherche Scientifique (INRS) have made a breakthrough in understanding the reason behind the virulence of leishmania parasite. The leishmania parasite is responsible for... more
Alzheimer’s disease risk gene is involved in synaptic transmission  NEWS MEDICAL · 4 days
A study published today in the journal Cell Reports sheds new light on how the CD2AP gene may enhance Alzheimer's disease susceptibility. more
Pinpointing the molecular mechanisms of ageing  PHYS.ORG · 4 days
Although each and every one of us goes through it, ageing is a poorly understood process. Researchers have used a biomarker called the epigenetic clock to identify a gene that is closely linked to ageing in... more
Monarchs caught up in rewrite of endangered species rule  PHYS.ORG · 5 days
Hand-raising monarch butterflies in the midst of a global extinction crisis, Laura Moore and her neighbors gather round in her suburban Maryland yard to launch a butterfly newly emerged from... more
Goodbye monarchs? Protection changes may imperil butterflies  PHYS.ORG · 5 days
Hand-raising monarch butterflies in the midst of a global extinction crisis, Laura Moore and her neighbors gather round in her suburban Maryland yard to launch a butterfly newly emerged from its chrysalis. Eager to... more
Not just genes: Environment also shaped population variation in first Americans  PHYS.ORG · 5 days
The first Americans—humans who crossed onto the North American continent and then dispersed throughout Central and South America—all share common ancestry. But as they settled different... more
Lost in translation: Researchers discover translator gene may play a role in disease  PHYS.ORG · 5 days
A molecule called tRNA, or transfer ribonucleic acid, is an essential component of the human genome that acts as a translator. It... more
DNA tests of UK waters could help catch invasive species early  SCIENCE DAILY · 5 days
Scientists have discovered several artificially introduced species in the coastal waters of southern England, using a technique that could help the early detection of non-native species... more
Lost in translation: Researchers discover translator gene may play a role in disease  SCIENCE DAILY · 5 days
A molecule called tRNA is an essential component of the human genome that acts as a translator. When researchers and clinicians investigate... more
Not just genes: Environment also shaped population variation in first Americans  SCIENCE DAILY · 5 days
A new study shows that facial differences resulting from population divergence in first Americans is due to the complex interaction of environment and evolution on these... more
Foraging for information: Machine learning decodes genetic influence over behavior  SCIENCE DAILY · 5 days
Mice scurry around while foraging for food, but genetics may be the unseen hand controlling these meandering movements. Researchers are using machine learning to draw links between genetic... more
Gene for acid-sensitive ion channel identified  PHYS.ORG · 5 days
In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems. Special channels in the cell membrane selectively permit salt ions to flow in and out of cells. A... more
Gene for acid-sensitive ion channel identified  SCIENCE DAILY · 5 days
In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems. Special channels in the cell membrane selectively permit salt ions to flow in and out of cells. A... more
Editorial: Trump guts the Endangered Species Act. Polar bears and bald eagles, take notice  PHYS.ORG · 5 days
The Trump administration announced reckless and potentially devastating new rules Monday that will weaken the Endangered Species Act, which currently... more
DNA tests of UK waters could help catch invasive species early  PHYS.ORG · 5 days
A team of scientists from the University of Southampton, Bangor University and the National Oceanography Centre have discovered several artificially introduced species in the coastal waters... more
Mysterious m6A marks on RNA begin to yield their secrets  PHYS.ORG · 5 days
Chemical modifications that appear on some RNA transcripts may have evolved in part to help cells repair themselves after damage, and may also be a key to understanding... more
Cow gut study finds bugs that could up yields  PHYS.ORG · 5 days
Cutting-edge DNA technologies have discovered thousands of bugs in cows' stomachs that could improve meat and dairy production, and keep cattle healthy. more
Rat detective uses DNA to uncover how rats scurry around cities  PHYS.ORG · 5 days
It's dark and I'm parked in an alley near a lopsided compost bin. I have a notepad, binoculars and a lukewarm cup of coffee—everything needed for... more
Ancient pigs endured a complete genomic turnover after they arrived in Europe  SCIENCE DAILY · 5 days
New research has resolved a pig paradox. Archaeological evidence has shown that pigs were domesticated in the Near East and as such, modern pigs... more
Meteorite strikes made life on Earth possible  PHYS.ORG · 5 days
Meteorites from the far reaches of the solar system delivered large amounts of water, carbon and volatile substances to the Earth. Only then could the Earth host life. Dr. María Isabel Varas-Reus, Dr. Stephan... more
DNA methylation may influence the effects of aspirin in patients with breast cancer  NEWS MEDICAL · 5 days
Women with a particular DNA feature may live longer if they take aspirin even before they are diagnosed with breast cancer, a... more
Do newly discovered mating habits of female Tasmanian devils help or hurt the species?  PHYS.ORG · 5 days
Wild female Tasmanian devils have mating habits that could pose a challenge for conservationists trying to maintain genetic diversity in... more
Researchers make scientific breakthrough regarding Leishmania virulence strategy  NEWS MEDICAL · 5 days
A team from the Institut National de la Recherche Scientifique has made a scientific breakthrough regarding the virulence strategy employed by the Leishmania parasite to infect cells of the immune system. more
Medical News Today: Schizophrenia: Genes related to circadian rhythms may be disrupted  MNT · 5 days
In the brains of people with schizophrenia, researchers have now found disrupted patterns in the expression of genes that correspond to sleep-wake cycles. more
Ancient pigs endured a complete genomic turnover after they arrived in Europe  PHYS.ORG · 6 days
New research led by Oxford University and Queen Mary University of London has resolved a pig paradox. Archaeological evidence has shown that pigs were... more
Diarrhea-causing bacteria adapted to spread in hospitals  SCIENCE DAILY · 6 days
Scientists have discovered that the gut-infecting bacterium Clostridium difficile is evolving into two separate species, with one group highly adapted to spread in hospitals. Researchers identified genetic changes in the newly emerging species that... more
Bacteria made to mimic cells, form communities  SCIENCE DAILY · 6 days
Scientists have found a way to make single-celled bacteria behave like stem cells, differentiating into genetically unique individuals as they divide. more
Inherited pancreatic cancer risk mutation identified  SCIENCE DAILY · 6 days
The discovery of the previously unknown mutation could lead to routine testing of individuals with a strong family history of pancreatic cancer to determine if they carry the mutation, occurring in the gene known as RABL3. more
Scientists identify hereditary pancreatic cancer risk mutation  NEWS MEDICAL · 6 days
Scientists studying a highly cancer-prone family have identified a rare, inherited gene mutation that dramatically raises the lifetime risk of pancreatic and other cancers. more
Trump overhauls endangered species protections  PHYS.ORG · 6 days
The Trump administration on Monday rolled out some of the broadest changes in decades to enforcement of the landmark Endangered Species Act, allowing the government to put an economic cost on saving a species and other changes critics... more
Genomic research unravels mystery of invasive apple snails  SCIENCE DAILY · 6 days
Biologists have sequenced and analyzed the genomes of four apple snail species in the family Ampullariidae. The researchers discovered that the apple snails have evolved to become highly sensitive to environmental stimuli,... more
Genomic research unravels mystery of invasive apple snails  PHYS.ORG · 6 days
Biologists from Hong Kong Baptist University (HKBU) have led a study to sequence and analyse the genomes of four apple snail species in the family Ampullariidae. The researchers discovered that the apple... more
A novel method to characterize genes with high-precision in single cells  PHYS.ORG · 6 days
The analysis of gene products in cells is an important tool for diagnosing disease and the design of new active substances in biological and medical research.... more
A novel method to characterize genes with high-precision in single cells  SCIENCE DAILY · 6 days
A method of targeted RNA sequencing (transcriptome analysis) has now been developed, which precisely detects the smallest amounts of gene transcripts in single cells. The method... more
Management of ovarian cancer risk in women with BRCA1/2 gene mutations  NEWS MEDICAL · 6 days
A new review to help physicians manage the risk of ovarian cancer in women who carry the BRCA1/2 gene mutations is published in CMAJ. more
An emerging view of RNA transcription and splicing  PHYS.ORG · 6 days
Cells often create compartments to control important biological functions. The nucleus is a prime example; surrounded by a membrane, it houses the genome. Yet cells also harbor enclosures that are not membrane-bound... more
Key phosphorus-based molecule for life on Earth may have come from space  PHYS.ORG · 6 days
The answer to "How did the first organisms on Earth incorporate the critical element phosphorus?" has been a quandary for researchers, but, University of... more
Biologists discover the intricacies of 'on/off switch' that creates cell differentiation  NEWS MEDICAL · 6 days
A team of biologists has discovered how cells become different from each other during embryogenesis, a finding that offers new insights into genetic activity and has... more
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