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Shy parent, shy child?
SCIENCE DAILY Previous research has shown that extreme shyness is hereditary, but because shyness is such a broad concept it is difficult to identify specific genes. One researcher has discovered particular brain measurements that can help. 4 hours
Two new breast cancer genes emerge from lynch syndrome gene study
SCIENCE DAILY Researchers have identified two new breast cancer genes that also cause Lynch syndrome. 12 hours
Can mice really mirror humans when it comes to cancer?
SCIENCE DAILY A new study is helping to answer a pressing question among scientists of just how close mice are to people when it comes to researching cancer. The findings... 12 hours
Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis
Science Magazine CD4+ cytotoxic T lymphocytes (CD4-CTLs) have been reported to play a protective role in several viral infections. However, little is known in humans about... 14 hours
A new, dynamic view of chromatin movements
SCIENCE DAILY In cells, proteins tightly package the long thread of DNA into pearl necklace-like complexes known as chromatin. Scientists now show for the first time how chromatin moves, answering longstanding questions about how its structure... 14 hours
Packing a genome, step-by-step
SCIENCE DAILY For the first time, scientists can see in minute-time resolution how cells package chromosomes into highly condensed structures prior to cell division. 15 hours
Researchers create first stem cells using CRISPR genome activation
SCIENCE DAILY In a scientific first, researchers have turned skin cells from mice into stem cells by activating a specific gene in the cells using CRISPR technology. The innovative approach offers a... 15 hours
Fanconi anemia: Insight from a green plant
PHYS.ORG Fanconi anemia is a human genetic disorder with severe effects, including an increased risk of cancer and infertility. Work in animal systems has identified many factors involved in Fanconi anemia and showed that these... 15 hours
Certain flu virus mutations may compensate for fitness costs of other mutations
SCIENCE DAILY Seasonal flu viruses continually undergo mutations that help them evade the human immune system, but some of these mutations can reduce a virus's potency.... 15 hours
Fragile X finding shows normal neurons that interact poorly
SCIENCE DAILY Neurons in mice afflicted with the genetic defect that causes Fragile X syndrome (FXS) appear similar to those in healthy mice, but these neurons fail to interact normally, resulting in... 15 hours
More genes are active in high-performance maize
PHYS.ORG When two maize inbred lines are crossed with each other, an interesting effect occurs: The hybrid offspring have a significantly higher yield than either of the two parent plants. Scientists at the University of... 20 hours
A pathway for mitotic chromosome formation
Science Magazine Mitotic chromosomes fold as compact arrays of chromatin loops. To identify the pathway of mitotic chromosome formation, we combined imaging and Hi-C of synchronous DT40 cell cultures with polymer simulations. We show that in prophase, the... 1 day
Detection and localization of surgically resectable cancers with a multi-analyte blood test
Science Magazine Earlier detection is key to reducing cancer deaths. Here we describe a blood test that can detect eight common cancer types through assessment of... 1 day
Researchers create first stem cells using CRISPR genome activation
PHYS.ORG In a scientific first, researchers at the Gladstone Institutes turned skin cells from mice into stem cells by activating a specific gene in the cells using CRISPR technology. The innovative... 1 day
Bovine tuberculosis shows genetic diversity throughout Africa
SCIENCE DAILY Bovine tuberculosis (BTB) is an infectious disease caused by Mycobacterium bovis that affects cattle as well as other animals and humans. Now, by combining genotyping M. bovis samples from cows across African countries, researchers... 1 day
Broad Institute takes a hit in European CRISPR patent struggle
Science Magazine European Patent Office revokes patent on gene-editing technology 2 days
Convergent evolution of gene regulation in humans and mice
SCIENCE DAILY Organisms that aren't closely related may evolve similar traits as they adapt to similar challenges. It's called convergent evolution, and familiar examples include the wings of birds, bats, and insects,... 2 days
Counting chromosomes: Plant scientists solve a century-old mystery about reproduction
PHYS.ORG Counting is vital in nature. Counting chromosomes is something that most animals, plants and even single-celled organisms need to know how to do to assure viability and to... 2 days
Packing a genome, step-by-step
PHYS.ORG Genome folding now has a playbook. A new step-by-step account spells out in minute-time resolution how cells rapidly pack long tangles of chromosomes into the tiny, tightly wound bundles needed for cell division. Cells reel chromosomes into loops, and then... 2 days
Genome-wide identification of interferon-sensitive mutations enables influenza vaccine design
Science Magazine In conventional attenuated viral vaccines, immunogenicity is often suboptimal. Here we present a systematic approach for vaccine development that eliminates interferon (IFN)–modulating functions genome-wide while maintaining virus replication fitness. We... 2 days
Study finds convergent evolution of gene regulation in humans and mice
PHYS.ORG Organisms that aren't closely related may evolve similar traits as they adapt to similar challenges. It's called convergent evolution, and familiar examples include the wings of... 2 days
Protein designed entirely from scratch functions in cells as a genuine enzyme
PHYS.ORG A dawning field of research, artificial biology, is working toward creating a genuinely new organism. At Princeton, chemistry professor Michael Hecht and the researchers... 2 days
Stem cell scientists chew on the mysteries of jaw development
PHYS.ORG Scientists in the USC Stem Cell laboratory of Gage Crump have revealed how key genes guide the development of the jaw in zebrafish. These findings may offer clues... 2 days
Study devises efficient and economical strategy to screen breast and ovarian cancer gene mutations
NEWS MEDICAL A new study published yesterday in the Journal of the National Cancer Institute suggests that, in comparison with just screening... 2 days
Modular gene enhancers may be suitable target in treatment of blood cancer
NEWS MEDICAL Every day, billions of new blood cells are generated in the bone marrow. The gene Myc is known to play an important role in... 2 days
Research reveals cost-effectiveness of whole-population screening for breast, ovarian cancer gene mutations
NEWS MEDICAL Screening the entire population for breast and ovarian cancer gene mutations, as opposed to just those at high-risk of carrying this mutation, is cost... 2 days
The Y chromosome is disappearing – so what will happen to men?
PHYS.ORG The Y chromosome may be a symbol of masculinity, but it is becoming increasingly clear that it is anything but strong and enduring. Although... 2 days
A new, dynamic view of chromatin movements
PHYS.ORG In cells, proteins tightly package the long thread of DNA into pearl necklace-like complexes known as chromatin. Scientists at EPFL show for the first time how chromatin moves, answering longstanding questions about how its... 2 days
The early bits of life
PHYS.ORG How can life originate before DNA and genes? One possibility is that there are natural processes that lead to the organisation of simple physical objects such as small microcapsules that undergo rudimentary forms of interaction, self-organisation and information... 2 days
Genes that Repair Spinal Cord in Fish also Present in Mammals, Researchers Discover
SCI-NEWS.COM Many of the genes involved in natural repair of the... 2 days
Novel gene expression analysis technique can accurately and quickly measure RNA
NEWS MEDICAL A University of Illinois and Mayo collaboration has demonstrated a novel gene expression analysis technique that can accurately measure levels of RNA quickly and directly from... 2 days
Review explores consequences of genetic testing and cancer risk-reducing surgery
NEWS MEDICAL Genetic testing is commonplace for many inheritable cancer syndromes, and with that comes the knowledge of being a gene carrier for some patients. 2 days
GA-map Dysbiosis Test identifies IBS patients who respond to FODMAP diet, study shows
NEWS MEDICAL Genetic Analysis, a leading Microbiome MDx specialist, today announced the publication of a new study in the peer-reviewed journal Digestive Disease and... 2 days
Novel chip-based gene expression tool analyzes RNA quickly and accurately
PHYS.ORG A University of Illinois and Mayo collaboration has demonstrated a novel gene expression analysis technique that can accurately measure levels of RNA quickly and directly from a cancerous... 2 days
DIPG tumor patterns offer new insight on survival
SCIENCE DAILY A small subset of patients with tumors that bear mutations in a gene in the basic packaging of DNA (known as histone mutations) may have better outcomes than others, suggests new research. 3 days
Modular gene enhancer promotes leukemia and regulates effectiveness of chemotherapy
SCIENCE DAILY Every day, billions of new blood cells are generated in the bone marrow. The gene Myc is known to play an important role in this process, and is... 3 days
Genetic study identifies six new gene regions associated with type 1 diabetes in children
NEWS MEDICAL This article outlines a recent study which identified six novel gene regions in children who are at risk of type... 3 days
Genetic study identifies six new genes associated with type 1 diabetes in children
NEWS MEDICAL This article outlines a recent study which identified six novel gene regions in children who are at risk of type 1 diabetes. 3 days
Tiger shark sex life fuels sustainability risk
PHYS.ORG Tiger sharks appear to be genetically monogamous – and it could be putting the species at risk. 3 days
Scientists identify six new gene regions that may help treat type 1 diabetes
NEWS MEDICAL Six novel chromosomal regions identified by scientists leading a large, prospective study of children at risk for type 1 diabetes will enable... 3 days
Three-dimensional organization of genome plays key role in gene expression, cell fate
NEWS MEDICAL Scientists have long been reading the code of life - the genome -, as a sequence of letters but now researchers have also started... 3 days
Gene Location for Paranoia Found
LIVE SCIENCE Researchers identified a genetic location linked to paranoia by studying a rare neurogenetic disorder. 3 days
DNA uncovers humans as the main source of faecal pollution in the Danube
PHYS.ORG Despite wastewater management and treatment plants, human waste remains the main source of microbial faecal pollution in the river Danube. This is... 3 days
Research: Men who lack HSD17B4 gene may be more susceptible to treatment-resistant prostate cancer
NEWS MEDICAL Cleveland Clinic researchers have confirmed for the first time a mechanistic link between the gene HSD17B4 and deadly, treatment-resistant prostate... 3 days
Genetic drift caught in action in invasive birds
PHYS.ORG Studies of island bird populations have taught us a lot about evolution, but it's hard to catch birds in the act of naturally colonizing new islands. Instead, a new study from The... 3 days
Memory gene goes viral
PHYS.ORG Two independent teams of scientists from the University of Utah and the University of Massachusetts Medical School have discovered that a gene crucial for learning, called Arc, can send its genetic material from one neuron to another by employing a... 4 days
Medical News Today: Diabetes: Surprising gene discovery could fuel new treatments
MNT Researchers have identified a single gene mutation that may be responsible for both high and low blood sugar levels in a single family. 4 days
Diabetes gene found that causes low and high blood sugar levels in the same family
SCIENCE DAILY A study of families with rare blood sugar conditions has revealed a new gene thought to be critical... 4 days
New dynamic statistical model follows gene expressions over time
SCIENCE DAILY A new model now gives researchers a tool that extends past observing static networks at a single snapshot in time, which is hugely beneficial since network data are usually dynamic. 4 days
'Magic pools' approach can hurry studies of novel bacteria
PHYS.ORG To characterize the genes of newly identified bacteria, microbiologists often introduce mutations within the bacteria using mobile DNA segments called transposons to study the impact of these mutations. 4 days
Scientists unleash power of genetic data to identify disease risk
SCIENCE DAILY Massive banks of genetic information are being harnessed to shed new light on modifiable health risks that underlie common diseases. Researchers have pioneered a method to integrate data... 4 days
New study offers insights on genetic indicators of COPD risk
SCIENCE DAILY Researchers have discovered that genetic variations in the anatomy of the lungs could serve as indicators to help identify people who have low, but stable, lung function early... 4 days
Computer-aided facial analysis helps diagnosis
SCIENCE DAILY In rare diseases, the computer-aided image analysis of patient portraits can facilitate and significantly improve diagnosis. This has been demonstrated on the basis of so-called GPI anchor deficiencies. Using data on genetic material, cell surface texture and typical... 4 days
Genome architecture's surprising role in cell fate decisions
SCIENCE DAILY A new study shows unexpected and crucial role of genome architecture in determining cell fate. The work represents an important advance in our understanding of gene regulation and reveals a new layer... 4 days
The impact of relatedness on grandmothers' desire to care for their grandchildren
PHYS.ORG Historically, the help provided by grandmothers has increased grandchild survival during times of high child mortality. However, there have been signs that in many... 4 days
Scholars develop new technology to decode gene transcription facilitating discovery of targeted therapy drugs
PHYS.ORG A research team from the School of Chinese Medicine (SCM) of Hong Kong Baptist University (HKBU) has developed the world's... 4 days
Genes involved in spinal cord repair of lamprey also present in mammals, study reveals
NEWS MEDICAL Many of the genes involved in natural repair of the injured spinal cord of the lamprey are also active in... 4 days
Researchers develop new dynamic statistical model to follow gene expressions over time
NEWS MEDICAL Researchers at Carnegie Mellon University have developed a new dynamic statistical model to visualize changing patterns in networks, including gene expression during developmental periods... 4 days
Study reveals new diabetes gene in families with rare blood sugar conditions
NEWS MEDICAL A study of families with rare blood sugar conditions has revealed a new gene thought to be critical in the regulation of insulin, the... 4 days
Lamprey genes provide clues to repair spinal cord damage, finds study
NEWS MEDICAL Researchers have found that several genes within an ancient species of fish can be used to provide clues in the treatment of spinal cord damage. The... 4 days
FDA grants approval for first drug to treat inherited breast cancer
NEWS MEDICAL The U.S. Food and Drug Administration today expanded the approved use of Lynparza (olaparib tablets) to include the treatment of patients with certain types of breast... 4 days
Researchers develop remote-controlled mechanogenetics system to target and kill cancer cells
NEWS MEDICAL A team of researchers has developed an ultrasound-based system that can non-invasively and remotely control genetic processes in live immune T cells so that they recognize... 4 days
Flipping the switch: Dietary fat, changes in fat metabolism may promote prostate cancer metastasis
SCIENCE DAILY Researchers have shed new light on the genetic mechanisms that promote metastasis in the mouse model and also implicated the... 4 days
Remote-controlled cancer immunotherapy system
SCIENCE DAILY A team of researchers has developed an ultrasound-based system that can non-invasively and remotely control genetic processes in live immune T cells so that they recognize and kill cancer cells. 4 days
Research sheds new light on genetic, environmental factors that promote prostate cancer metastasis
NEWS MEDICAL Prostate tumors tend to be what scientists call "indolent" - so slow-growing and self-contained that many affected men die with prostate cancer,... 4 days
Surfers three times more likely to have antibiotic-resistant bacteria in guts
SCIENCE DAILY Scientists compared fecal samples from surfers and non-surfers to assess whether the surfers' guts contained E. coli bacteria that were able to grow in the presence... 4 days
Genes that aid spinal cord healing in lamprey also present in humans, researchers discover
SCIENCE DAILY Many of the genes involved in natural repair of the injured spinal cord of the lamprey are also active in... 5 days
Impact of relatedness on grandmothers’ desire to care for their grandchildren
SCIENCE DAILY Historically, grandmothers have been important to their grandchildren, and the help provided by grandmothers has increased grandchild survival during the times of high child mortality. However,... 5 days
New dynamic statistical model follows gene expressions over time
PHYS.ORG Researchers at Carnegie Mellon University have developed a new dynamic statistical model to visualize changing patterns in networks, including gene expression during developmental periods of the brain. 5 days
Genes that repair spinal cord in fish are also in humans, researchers find
SCIENCE DAILY Many of the genes that repair an injured spinal cord in a fish called the lamprey are also active in the repair... 5 days
Genetic Variation between Pathogen Strains Contributes to Diverse Patient Immune Responses
SCI-NEWS.COM Individuals have wide-ranging physiological responses to the same species of pathogen. Researchers have demonstrated... 5 days
Medical News Today: How dietary fat helps prostate cancer to spread
MNT Scientists unravel the link between genetics and dietary fat and the role they play in the progression and spread of prostate cancer. 5 days
Unexpected environmental source of methane discovered
SCIENCE DAILY Roughly 10 percent of nitrogen-fixing microorganisms contain the genetic code for manufacturing a back-up enzyme, called iron iron-only nitrogenase, to do their job. New research reveals that this enzyme allows these microorganisms to convert nitrogen gas... 5 days
Fast-tracking T cell therapies with immune-mimicking biomaterials
PHYS.ORG Immunologists and oncologists are harnessing the body's immune system to fight cancers and other diseases with adoptive cell transfer techniques. In a normal immune response, a type of white blood cell known as T... 5 days
When a country's towns and villages face extinction
PHYS.ORG It is predicted that 896 towns and villages across Japan will no longer be viable by 2040 (see map below or an interactive Japanese version here). A former minister for internal affairs,... 5 days
Variations in bacterial strains can trigger varying immune responses, study states
NEWS MEDICAL A new study published in PLOS Pathogens revealed the role of genetic variations between different strains of the same bacterial species in inducing variations in immune... 5 days
New polygenic hazard score predicts when men develop prostate cancer
SCIENCE DAILY Medical researchers have developed and validated a genetic tool for predicting age of onset of aggressive prostate cancer, a disease that kills more than 26,000 American men annually. 1 week
Past exposures shape immune response in pediatric acute respiratory infections
SCIENCE DAILY By analyzing immune cells of children who came to the emergency department with flu symptoms, researchers found that the suite of genes these early-response cells expressed was shaped... 1 week
US OKs 1st drug aimed at women with inherited breast cancer
ABC NEWS U.S. regulators have approved the first drug aimed at breast cancer patients who have an inherited mutation in the BRCA gene 1 week
Genetic analysis can improve depression therapy
SCIENCE DAILY The failure of SSRI antidepressants can be a result of genetic variations in patients. Variations within the gene that encodes the CYP2C19 enzyme results in extreme differences in the levels of escitalopram achieved in patients, according... 1 week
Different strains of same bacteria trigger widely varying immune responses
SCIENCE DAILY Genetic differences between different strains of the same pathogenic bacterial species appear to result in widely varying immune system responses, according to new research. 1 week
Discovery of a new source of world's deadliest toxin
PHYS.ORG Researchers from the Quadram Institute have identified genes encoding a previously undiscovered version of the botulinum neurotoxin in bacteria from a cow's gut. 1 week
Researchers discover new type of botulinum neurotoxin from unexpected source
NEWS MEDICAL Researchers from the Quadram Institute have identified genes encoding a previously undiscovered version of the botulinum neurotoxin in bacteria from a cow's gut. 1 week
The nanoscopic structure that locks up our genes
PHYS.ORG For decades, scientists could only speculate about the shape of heterochromatin, a type of chromatin that consists of tightly packed DNA and proteins. Recently, however, researchers from the Okinawa Institute of Science... 1 week
Study suggests shared genetic susceptibility to epilepsy and mood disorders
NEWS MEDICAL Mood disorders, including depression, are the most common comorbid conditions in individuals with epilepsy, but the cause remains unclear, according to a latest study by researchers at Columbia... 1 week
RAS dimers essential for causing cancer, study shows
NEWS MEDICAL Mutated RAS genes are some of the most common genetic drivers of cancer, especially in aggressive cancers like pancreatic and lung cancer, but no medicines that target RAS are available despite decades... 1 week
Novel polygenic hazard score captures age variations of aggressive prostate cancer
NEWS MEDICAL An international team, led by researchers at the University of California San Diego School of Medicine, has developed and validated a genetic tool for predicting age... 1 week
BRCA gene mutation does not raise the risk of death
NEWS MEDICAL BRCA gene mutation has been associated with cancers such as breast cancer. The BRCA gene mutation detection had resulted in a prophylactic double mastectomy for actress Angelina Jolie... 1 week
All in the family: Focused genomic comparisons
SCIENCE DAILY Aspergillus fungi are pathogens, decomposers, and important sources of biotechnologically-important enzymes. Scientists now report the first outcome from the large-scale sequencing of 300+ Aspergillus species. These findings are a proof of concept of novel... 1 week
Northern corn leaf blight genes identified in new study
SCIENCE DAILY Midwestern corn growers know the symptoms of northern corn leaf blight all too well: greenish-gray lesions on the leaves that can add up to major yield losses if not detected... 1 week
Protecting corridors is critical to preserving genetic diversity in tigers, and mizimising extinction, study finds
SCIENCE DAILY Tigers have lost 95% of their historical range, and what remains is highly fragmented. According to a new... 1 week
Mount Sinai study uncovers potential link between Crohn's and Parkinson's in Jewish population
NEWS MEDICAL Mount Sinai Researchers have just discovered that patients in the Ashkenazi Jewish population with Crohn's disease (a chronic inflammatory of the digestive... 1 week
Northern corn leaf blight genes identified in new study
PHYS.ORG Midwestern corn growers know the symptoms of northern corn leaf blight all too well: greenish-gray lesions on the leaves that can add up to major yield losses if not detected... 1 week
Biologists peek into the past to see the future through tiny spider eyes
SCIENCE DAILY Biologists look to the past for early genetic development of tiny spider and insect eyes to find potential for research into human... 1 week
What happens when your brain's support cells aren't so supportive?
SCIENCE DAILY Salk scientists use gene expression to understand how astrocytes change with age. 1 week
Researchers map druggable genomic targets in evolving malaria parasite
SCIENCE DAILY Researchers have used whole genome analyses and chemogenetics to identify new drug targets and resistance genes in 262 parasite cell lines of Plasmodium falciparum -- protozoan pathogens that cause malaria... 1 week
The nanoscopic structure that locks up our genes
SCIENCE DAILY Wireless headphones, two yo-yos connected by a string, earmuffs: all these items could be used to describe a tiny structure inside a cell's nucleus. For decades, scientists could only speculate about the... 1 week
Biologists look to the past for early genetic development of tiny spider and insect eyes
PHYS.ORG VIDEO With the increasing advantages of DNA sequencing, University of Cincinnati biologists are unraveling many evolutionary mysteries behind the... 1 week
Not all strep infections are alike and it may have nothing to do with you
SCIENCE-NEWS Add-on genes in some bacteria shape the way strains interact with the immune system. 1 week
Could science destroy the world? These scholars want to save us from a modern-day Frankenstein
Science Magazine
Biologists look to the past for early genetic development of tiny spider and insect eyes
PHYS.ORG