Gene Editing
Using CRISPR for dose-dependent activation of gene expressions  PHYS.ORG · 19 hours
A team of researchers affiliated with several institutions in the U.S. has developed a way to use the CRISPR gene editing technique for dose-dependent activation of gene expressions. In their paper published... more
CRISPR: More than just for gene editing?  SCIENCE DAILY · 2 days
Researchers have converted the CRISPR 'recognition induced enzymatic signal' to an electrical signal, which was then used to detect the biomarkers for viruses such as HPV or parvo. They hope the end result could... more
CRIPSR could be used to detect disease  NEWS MEDICAL · 2 days
CRISPR could be used to establish new diagnostic blood tests by identifying viral nucleic acids, such as Parvo or HPV. more
Horizon Discovery announces divestment of animal models business to Envigo  NEWS MEDICAL · 2 days
Horizon Discovery Group plc, a global leader in the application of gene editing and gene modulation technologies, today announces an agreement to divest the Group’s animal research models... more
New point-of-care medical device rapidly and accurately detects viruses  NEWS MEDICAL · 2 days
The gene-editing tool CRISPR has been heralded as a scientific miracle destined to eradicate diseases from sickle-cell anemia to cancer, or decried as "the genetic scissors that tailor the human... more
CRISPR: More than just for gene editing?  PHYS.ORG · 2 days
The gene-editing tool CRISPR has been heralded as a scientific miracle destined to eradicate diseases from sickle-cell anemia to cancer, or decried as "the genetic scissors that tailor the human gene pool," an ethically... more
Modified CRISPR gene editing tool could improve therapies for HIV, sickle cell disease  PHYS.ORG · 6 days
City of Hope researchers may have found a way to sharpen the fastest, cheapest and most accurate gene editing technique, CRISPR-Cas9, so... more
Improved gene editing technique can successfully cut out undesirable genetic information  NEWS MEDICAL · 6 days
City of Hope researchers may have found a way to sharpen the fastest, cheapest and most accurate gene editing technique, CRISPR-Cas9, so that it can more... more
A new CRISPR-Cas9 protein to increase precision of gene editing  SCIENCE DAILY · 6 days
Researchers have recently developed a new protein that can help increase the targeting accuracy in the genome editing process. It is believed that it would be useful for... more
Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy  Science Magazine · 7 days
The PINK1 protein kinase activates the PARK2 ubiquitin ligase to promote mitochondrial ubiquitylation and recruitment of ubiquitin-binding mitophagy receptors typified by OPTN... more
CRISPR-Cas9 protein can help increase targeting accuracy in genome editing process  NEWS MEDICAL · 7 days
A team of researchers from City University of Hong Kong and Karolinska Institutet has recently developed a new protein that can help increase the targeting accuracy... more
A new CRISPR-Cas9 protein to increase precision of gene editing  PHYS.ORG · 7 days
A team of researchers from City University of Hong Kong (CityU) and Karolinska Institutet has recently developed a new protein that can help increase the targeting accuracy in... more
Doctors try CRISPR gene editing for cancer, a 1st in the US  ABC NEWS · 7 days
1st attempt in US to use a gene editing tool called CRISPR against cancer seems safe in 3 patients who have had it so... more
CRISPR Approach To Fighting Cancer Called 'Promising' In 1st Safety Test  NPR · 7 days
Attempts to use the gene-editing tool CRISPR to develop a treatment for cancer seem safe and feasible in the earliest findings from the first three patients.... more
The evolution of genetic engineering  PHYS.ORG · 1 week
Charles Gersbach, the Rooney Family Associate Professor of Biomedical Engineering at Duke University, leads a lab that is centered on developing and applying genome engineering tools––most notably CRISPR-based technology. CRISPR-Cas is a bacterial defense system that allows bacteria... more
Developing new delivery tools for gene editing  SCIENCE DAILY · 2 weeks
Scientists are using simple peptides to deliver gene-editing tools into notoriously hard-to-access lung and airway cells with the goal of creating new treatments for people with diseases like cystic fibrosis, COPD, and asthma. more
UI scientists are developing new delivery tools for gene editing  NEWS MEDICAL · 2 weeks
News of advances in gene-editing technology raises the prospect of actually using this approach to treat disease in patients. But one of the hurdles that remains is how... more
Improved Cas9 enzyme reduces chance of off-target CRISPR mutations  NEWS MEDICAL · 2 weeks
Genomics experts have discovered that when guide RNAs (gRNA) are designed properly, the risk of off-target mutations induced by the cas9 enzyme is very rare. more
New CRISPR genome “prime editing” system  NEWS MEDICAL · 3 weeks
Gene editing to correct genetic faults and removing the risk of hereditary diseases may soon become reality. Researchers have come up with a new gene editing technology that could help patients with sickle cell anaemia and... more
Scientists Create New, More Powerful Technique To Edit Genes  NPR · 3 weeks
A new technique, dubbed 'prime editing,' appears to make it even easier to make very precise changes in DNA. It's designed to overcome the limits of the CRISPR gene editing... more
New CRISPR genome editing system offers a wide range of versatility in human cells  PHYS.ORG · 3 weeks
A team from the Broad Institute of MIT and Harvard has developed a new CRISPR genome-editing approach by combining two... more
New CRISPR genome editing system offers a wide range of versatility in human cells  SCIENCE DAILY · 3 weeks
A team has developed a new CRISPR genome-editing approach by combining two of the most important proteins in molecular biology... more
Researchers quantify Cas9-caused off-target mutagenesis in mice  SCIENCE DAILY · 4 weeks
Scientists are finding new ways to improve the use of the CRISPR enzyme Cas9 and reduce the chances of off-target mutations in laboratory mice, according to new results. The findings will help scientists contextualize... more
Oxford Genetics and Sphere Fluidics announce a multi-partner collaboration  NEWS MEDICAL · 4 weeks
Oxford Genetics and Sphere Fluidics announce a multi-partner collaboration to expedite the development of automated microfluidic systems for rapid and high-throughput gene editing in mammalian cell lines. more
CRISPR helps find difficult to detect cancer cells  NEWS MEDICAL · 4 weeks
Immunotherapy is one of the latest and most effective armaments against various types of cancers. Some of the immunotherapy drugs such as PD-1 inhibitor Keytruda from Merck can block certain proteins in... more
Widely Publicized Study on CRISPR Babies' Gene Mutation Now Retracted for Errors  LIVE SCIENCE · 4 weeks
A widely publicized study that suggested that the first gene-edited "CRISPR" babies could have shorter lifespans has been retracted due to crucial errors in... more
Study suggesting that CRISPR babies are likely to die early has been retracted  NEWS MEDICAL · 4 weeks
A research paper that sparked concerns about the lifespan of China's first gene-edited babies has been retracted due to technical errors. more
AAV vector integration into CRISPR-induced DNA breaks  PHYS.ORG · 4 weeks
To design safe clinical trials, it is crucial to better understand and predict gene editing outcomes in preclinical studies. Bence György and collaborators have shown that adeno-associated viruses (AAVs) can stably integrate into CRISPR-Cas9-induced... more
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