DNA
Oldest African DNA on record shines light on the deep human past  NEWS MEDICAL · 5 hours
A team of international researchers, which includes a Saint Louis University Madrid anthropologist, dug deep to find some of the oldest African DNA on... more
Here, there and everywhere: Large and giant viruses abound globally  SCIENCE DAILY · 8 hours
Scientists have uncovered a broad diversity of large and giant viruses that belong to the nucleocytoplasmic large DNA viruses (NCLDV) supergroup. As a result, virus diversity in this... more
Surprise discovery shakes up our understanding of gene expression  SCIENCE DAILY · 10 hours
A group of scientists has uncovered a previously unknown way that our genes are made into reality. Rather than directions going one-way from DNA to RNA to proteins, the latest... more
'Ghost' population of humans discovered in ancient Africa  LIVE SCIENCE · 9 hours
The ancient DNA from four children who lived thousands of years ago is rewriting what geneticists thought happened in sub-Saharan Africa. more
Isothermal digital detection of microRNAs using background-free molecular circuit  Science Magazine · 12 hours
MicroRNAs, a class of transcripts involved in the regulation of gene expression, are emerging as promising disease-specific biomarkers accessible from tissues or bodily fluids. However, their accurate quantification from biological... more
First ancient DNA from West/Central Africa illuminates deep human past  PHYS.ORG · 13 hours
An international team led by Harvard Medical School scientists has produced the first genome-wide ancient human DNA sequences from west and central Africa. more
Urine fertilizer: 'Aging' effectively protects against transfer of antibiotic resistance  PHYS.ORG · 23 hours
Recycled and aged human urine can be used as a fertilizer with low risks of transferring antibiotic resistant DNA to the environment, according to new research from the... more
George Mason University researchers receive $314,000 to design better vaccines  NEWS MEDICAL · 1 day
George Mason University's Aarthi Narayanan, Associate Professor, College of Science and the National Center for Biodefense and Infectious Disease, and Remi Veneziano, Assistant Professor, Volgenau School of Engineering,... more
Scientists uncover new mode of evolution  LIVE SCIENCE · 1 day
Scientists have discovered a form of natural selection that doesn't rely on DNA. more
Microbiome DNA signature present in human fetal lungs  NEWS MEDICAL · 5 days
The lungs and placentas of fetuses in the womb -- as young as 11 weeks after conception -- already show a bacterial microbiome signature, which suggests that bacteria may colonize the lungs... more
Low doses of radiation used in medical imaging lead to mutations in cell cultures  SCIENCE DAILY · 6 days
Common medical imaging procedures use low doses of radiation that are believed to be safe. A new study, however, finds... more
Programmable nests for cells  PHYS.ORG · 6 days
Using DNA, small silica particles, and carbon nanotubes, researchers of Karlsruhe Institute of Technology (KIT) have developed novel programmable nanocomposites that can be tailored to various applications and programmed to degrade quickly and gently. For medical applications, they can create... more
Programmable nests for cells  nanowerk · 6 days
Researchers developed novel composites of DNA, silica particles, and carbon nanotubes - properties can be tailored to various applications. more
Hormone resistance in breast cancer linked to DNA 'rewiring'  SCIENCE DAILY · 6 days
Researchers have revealed changes to the 3D arrangement of DNA linked to treatment resistance in ER+ breast cancer. more
Genetically engineered mosquitoes halt Dengue spread  NEWS MEDICAL · 6 days
A new study published in the journal PLOS Pathogens in January 2020 reports the development of mosquitoes that have been genetically modified to resist infection by several types of the dengue virus. This is the first... more
3D structure of DNA is 'rewired' in hormone-resistant ER+ breast cancers  NEWS MEDICAL · 6 days
Epigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatment for ER+ breast cancer, which... more
Microscopy technique reveals cells' 3-D ultrastructure in new detail  PHYS.ORG · 7 days
Inside a cell, tentacled vesicles shuttle cargo for sorting. DNA rearranges in the nucleus as stem cells differentiate into neurons. Neighboring neurons cling to one another through a web-like interface.... more
Exploring tiny forces with single molecule force spectroscopy  PHYS.ORG · 7 days
In terms of space organization, DNA has powers rivaling Marie Kondo. A strand of DNA that is two meters long intricately folds itself into a cell nucleus only 10 microns across. (One... more
New mechanisms describe how the genome regulates itself  PHYS.ORG · 7 days
An organism's genome contains all of the information necessary for each of its cells and tissues to develop and function properly. Written in DNA, each individual gene encodes for something, whether it... more
Analyzing DNA in soil could be an effective way of tracking animals  SCIENCE DAILY · 1 week
Genetic material left behind by animals can provide critical clues to aid conservation and research. New research shows studying DNA in soil samples can... more
DNA Damage to Breast Cells from chemicals in some cosmetics, sunscreens  SCIENCE DAILY · 1 week
A new approach to studying the effects of two common chemicals used in cosmetics and sunscreens found they can cause DNA damage in breast cells at... more
Opening up DNA to delete disease  SCIENCE DAILY · 1 week
Protein editorial assistants are clearing the way for cut-and-paste DNA editors, like CRISPR, to access previously inaccessible genes of interest. Opening up these areas of the genetic code is critical to improving CRISPR efficiency and moving... more
Infectious disease defenses among ancient hominid contributions to adaptation of modern humans  PHYS.ORG · 1 week
During the past decade, our human evolutionary tree has turned into something more resembling an unwieldy bush. Scientists have discovered swapped segments of DNA... more
Unique tool to democratize entry into the field of nanopore research  NEWS MEDICAL · 1 week
A nanopore is a tiny hole in a thin membrane with a diameter of around a billionth of a meter, or about the width of a... more
Analyzing DNA in soil could be an effective way of tracking animals  PHYS.ORG · 1 week
It's hard to protect something you can't find. A new Stanford study reveals sampling soil for animals' left-behind DNA can provide valuable information for... more
World's First 'Living Machine' Created Using Frog Cells and Artificial Intelligence  LIVE SCIENCE · 1 week
Scientists used computer algorithms to "evolve" an organism that's made of 100% frog DNA — but it isn't a frog. more
Evonetix and imec partner to increase production of chip-based technology for desktop DNA platform  NEWS MEDICAL · 1 week
EVONETIX LTD, the synthetic biology company developing a desktop platform for scalable, high-fidelity and rapid gene synthesis, today announced it... more
A tool to democratize nanopore research  PHYS.ORG · 1 week
A nanopore is a tiny hole in a thin membrane with a diameter of around a billionth of a meter, or about the width of a single DNA molecule. The potential applications of these nanopores are... more
Custom-built molecules enable editing of genes previously obscured by DNA's innately protective structure  PHYS.ORG · 1 week
Protein editorial assistants are clearing the way for cut-and-paste DNA editors, like CRISPR, to access previously inaccessible genes of interest. Opening up... more
The circadian clock is key to reducing radiation‐induced cardiotoxicity  NEWS MEDICAL · 1 week
Treatment for breast cancer commonly includes radiation therapy, which offers good chances of success but comes with a serious long-term side effect: toxicity due to radiation that reaches the heart,... more
Nano-objects of desire: Assembling ordered nanostructures in 3D  SCIENCE DAILY · 1 week
A new DNA-programmable nanofabrication platform organizes inorganic or biological nanocomponents in the same prescribed ways. more
Nano-objects of desire: Assembling ordered nanostructures in 3D  nanowerk · 1 week
Using shape-programmable DNA frames, scientists established a new nanofabrication platform for directing nanomaterial components of different natures (inorganic and biological) into 3-D arrays with prescribed organizations; they then demonstrated the enhanced optical... more
Nano-objects of desire: Assembling ordered nanostructures in 3-D  PHYS.ORG · 1 week
Scientists have developed a platform for assembling nanosized material components, or "nano-objects," of very different types—inorganic or organic—into desired 3-D structures. Though self-assembly (SA) has successfully been used to organize nanomaterials of... more
A new model of metabolism draws from thermodynamics and 'omics'  PHYS.ORG · 1 week
All living things are made of carbon, and sugars like glucose are a very common source of it. Consequently, most cells are good at eating sugars, using enzymes... more
New mathematical model can efficiently model the expression of enzymes in living cells  NEWS MEDICAL · 1 week
All living things are made of carbon, and sugars, e.g. glucose, are a very common source of it. Consequently, most cells are... more
Chromatin organizes itself into 3D 'forests' in single cells  SCIENCE DAILY · 2 weeks
Scientists are increasingly interested in the function of chromatin -- a mix of DNA and protein within chromosomes -- and its role in disease. Using mathematical modeling and optical imaging... more
Beyond mass spectrometry, the next step in proteomics  Science Magazine · 2 weeks
Proteins can be the root cause of a disease, and they can be used to cure it. The need to identify these critical actors was recognized early (1951) by Sanger; the first... more
Chromatin organizes itself into 3-D 'forests' in single cells  PHYS.ORG · 2 weeks
A single cell contains the genetic instructions for an entire organism. This genomic information is managed and processed by the complex machinery of chromatin—a mix of DNA and protein within... more
Physical and data structure of 3D genome  Science Magazine · 2 weeks
With the textbook view of chromatin folding based on the 30-nm fiber being challenged, it has been proposed that interphase DNA has an irregular 10-nm nucleosome polymer structure whose folding philosophy is unknown. Nevertheless,... more
Scientists discover a new way to combine coding languages into single "bilingual" molecule  NEWS MEDICAL · 2 weeks
The nucleic acids of DNA encode genetic information, while the amino acids of proteins contain the code to turn that information into... more
Scientists find way to combine two main coding languages into single 'bilingual' molecule  NEWS MEDICAL · 2 weeks
The nucleic acids of DNA encode genetic information, while the amino acids of proteins contain the code to turn that information into... more
Common chemical disrupts reproductive biology  SCIENCE DAILY · 2 weeks
Experiments in worms reveal the molecular damage caused by DEHP, a chemical commonly used to make plastics flexible. DEHP interferes with proper cell division during egg formation, leads to excessive DNA breakage, alters chromosome appearance. Abnormalities help explain... more
'Bilingual' molecule connects two basic codes for life  PHYS.ORG · 2 weeks
The nucleic acids of DNA encode genetic information, while the amino acids of proteins contain the code to turn that information into structures and functions. Together, they provide the two fundamental codes... more
'Bilingual' molecule connects two basic codes for life  SCIENCE DAILY · 2 weeks
The nucleic acids of DNA encode genetic information, while the amino acids of proteins contain the code to turn that information into structures and functions. Together, they provide the two fundamental codes... more
Researchers identify new mechanism associated with p53 mutation  NEWS MEDICAL · 2 weeks
More than half of cancer cases worldwide are associated with genetic mutations in p53, the protein responsible for protecting DNA from changes that can lead to cancer. more
Scientists improve yield predictions based on seedling data  SCIENCE DAILY · 2 weeks
A doctor diagnosing a 50-year-old patient based on a blood test taken during the patient's infancy would be unthinkable. Anecdotally speaking, however, that's what scientists have done with corn. Using plant RNA... more
DNA-dependent protein kinase promotes DNA end processing by MRN and CtIP  Science Magazine · 2 weeks
The repair of DNA double-strand breaks occurs through nonhomologous end joining or homologous recombination in vertebrate cells—a choice that is thought to be decided by a... more
Hobbyist DNA services may be vulnerable to genetic hacking  NEWS MEDICAL · 2 weeks
Online services that allow users to upload their genetic information, research genealogy and find lost relatives may be vulnerable to a sort of genetic hacking, according to two geneticists at... more
Major genetic study provides most comprehensive map of breast cancer risk variants to date  NEWS MEDICAL · 2 weeks
A major international study of the genetics of breast cancer has identified more than 350 DNA 'errors' that increase an... more
Genetic study provides most comprehensive map of risk to date of breast cancer risk  SCIENCE DAILY · 2 weeks
A major international study of the genetics of breast cancer has identified more than 350 DNA 'errors' that increase an... more
Scientists discover the mechanism of DNA high-order structure formation  SCIENCE DAILY · 2 weeks
A team of molecular biologists have uncovered how one particular mechanism uses energy to ensure proper histone placement onto DNA to form chromatin. more
Researchers suggest a pathway to reverse the genetic defect of Friedreich's ataxia  SCIENCE DAILY · 2 weeks
Scientists have identified a molecular mechanism that could reverse the genetic defect responsible for Friedreich's ataxia, a neurodegenerative disease that leaves its victims with... more
Some genetic sequencing fail to analyze large segments of DNA  SCIENCE DAILY · 2 weeks
Children who undergo expansive genetic sequencing may not be getting the thorough DNA analysis their parents were expecting, say experts. more
Whole exome sequencing routinely fails to adequately analyze large segments of DNA  NEWS MEDICAL · 2 weeks
Children who undergo expansive genetic sequencing may not be getting the thorough DNA analysis their parents were expecting, say experts at UT Southwestern Medical... more
Virus used in gene therapies may pose cancer risk, dog study hints  Science Magazine · 2 weeks
Delivered DNA integrates into host genome, stabilizing protein production but stirring fears of mutating cell growth genes more
DNA tests to provide rapid diagnosis of rare diseases in critically ill infants  NEWS MEDICAL · 3 weeks
NHS England is will now provide new DNA testing that can rapidly diagnose rare diseases in critically ill babies and children. more
Snake-like proteins can wrangle DNA  PHYS.ORG · 3 weeks
It turns out the coiled snakes often used to symbolize medical knowledge are more than apt. They also mimic a key to life itself. more
Snake-like proteins can wrangle DNA  SCIENCE DAILY · 3 weeks
Theoretical simulations suggest structural maintenance of chromosome proteins coil not only around each other but also around the strands of DNA they help manipulate. These strands are formed into loops that regulate transcription and other cellular processes. more
Topological mechanics of knots and tangles  Science Magazine · 3 weeks
Knots play a fundamental role in the dynamics of biological and physical systems, from DNA to turbulent plasmas, as well as in climbing, weaving, sailing, and surgery. Despite having been studied for centuries, the subtle interplay... more
Areas to watch in 2020, and how carnivorous plants evolved impressive traps  Science Magazine · 3 weeks
We start our first episode of the new year looking at future trends in policy and research with host Joel Goldberg and several Science... more
AMSBIO's cfPure kits for rapid and efficient isolation of circulating cell free DNA  NEWS MEDICAL · 3 weeks
AMSBIO has expanded its range of cfPure Cell Free DNA Purification Kits for rapid and efficient isolation of circulating cell free DNA... more
CHK2-FOXK axis promotes transcriptional control of autophagy programs  Science Magazine · 3 weeks
Autophagy is an evolutionarily conserved catabolic process, which plays a vital role in removing misfolded proteins and clearing damaged organelles to maintain internal environment homeostasis. Here, we uncovered the checkpoint kinase 2... more
eDNA expands species surveys to capture a more complete picture  PHYS.ORG · 3 weeks
Tiny bits of DNA collected from waters off the West Coast allowed scientists to identify more species of marine vertebrates than traditional surveys with trawl nets. They also... more
Life could have emerged from lakes with high phosphorus  PHYS.ORG · 3 weeks
Life as we know it requires phosphorus. It's one of the six main chemical elements of life, it forms the backbone of DNA and RNA molecules, acts as the main... more
Identical twins with ASD have large differences in symptom severity  NEWS MEDICAL · 4 weeks
Identical twins with autism spectrum disorder often experience large differences in symptom severity even though they share the same DNA, according to an analysis funded by the National... more
Scientists reveal function of histone variant H2A.Z in DNA replication selection  PHYS.ORG · 4 weeks
DNA replication is a tightly regulated process that ensures the precise duplication of the genome during cell proliferation. Replication origins determine where replication starts on the... more
New insight into how dividing cells control the separation of their dna  PHYS.ORG · 4 weeks
A study published today in the journal eLife has shown that a protein called Astrin is important for the timely and even separation of... more
Medical News Today: Aspirin: Friend or foe after breast cancer?  MNT · 4 weeks
A new study focuses on DNA change to investigate why aspirin use is linked to different outcomes in different individuals after a breast cancer diagnosis. more
Expanding virophage diversity  PHYS.ORG · 4 weeks
Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant viruses. Almost all known virophage genomes share only four genes in common: major and minor capsid proteins (MCP and mCP, respectively), ATPase involved in DNA... more
How cells relieve DNA replication stress  PHYS.ORG · 4 weeks
DNA stores all of the information necessary for life phenomena, and a cell transmits its own genetic information to two daughter cells through DNA replication and cell division. Replication stress can be caused by extracellular and... more
Inserting end-modified DNA fragments with CRISPR-Cas9 yields highest efficiency  NEWS MEDICAL · 1 month
University of Illinois researchers achieved the highest reported rates of inserting genes into human cells with the CRISPR-Cas9 gene-editing system, a necessary step for harnessing CRISPR for clinical gene-therapy applications. more
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