DNA
Using CRISPR to program gels with new functions  PHYS.ORG · 6 hours
The CRISPR genome-editing system is best-known for its potential to correct disease-causing mutations and add new genes into living cells. Now, a team from MIT and Harvard University has deployed CRISPR for... more
Living Cells Can Record and Track Genomic Events with New “Designer Cell” Computer Technology  NEWS MEDICAL · 6 hours
Published in Molecular Cell, researchers at Massachusetts Institute of Technology (MIT) have developed a new technology that uses DNA to... more
Harnessing power of CRISPR to control behavior of DNA-responsive materials  NEWS MEDICAL · 11 hours
The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies... more
Scientists In New York Are Trying To Edit The DNA In Human Sperm  NPR · 19 hours
NPR got exclusive access to the only lab known to be trying to edit the DNA in human sperm, which raises all... more
Using CRISPR to program gels with new functions  MIT · 24 hours
Smart materials change properties in response to specific DNA sequences; could be used in a variety of devices. more
Programmable CRISPR-responsive smart materials  Science Magazine · 23 hours
Stimuli-responsive materials activated by biological signals play an increasingly important role in biotechnology applications. We exploit the programmability of CRISPR-associated nucleases to actuate hydrogels containing DNA as a structural element or as an anchor for pendant groups. After activation by... more
High-precision technique stores cellular 'memory' in DNA  SCIENCE DAILY · 1 day
Researchers have created a technology called DOMINO to store complex 'memories' in the DNA of living cells, including human cells. This memory storage capacity can form the foundation of complex circuits that trigger a... more
Slow electrons to combat cancer  SCIENCE DAILY · 1 day
Slow electons can be used to destroy cancer cells - but how exactly this happens has not been well understood. Now scientists have been able to demonstrate that a previously little-observed effect actually plays a pivotal role: Due... more
Slow electrons to combat cancer  PHYS.ORG · 1 day
Ion beams are often used today in cancer treatment: this involves electrically charged atoms being fired at the tumour to destroy cancer cells. Although, it's not actually the ions themselves that cause the decisive damage. When ions penetrate... more
There are way more species of horseshoe bats than scientists thought  SCIENCE DAILY · 1 day
Horseshoe bats are bizarre-looking animals with giant ears and elaborate flaps of skin on their noses that they use like satellite dishes. There are about a... more
High-precision technique stores cellular 'memory' in DNA  PHYS.ORG · 1 day
Using a technique that can precisely edit DNA bases, MIT researchers have created a way to store complex "memories" in the DNA of living cells, including human cells. more
There are way more species of horseshoe bats than scientists thought  PHYS.ORG · 1 day
Horseshoe bats are bizarre-looking animals with giant ears and elaborate flaps of skin on their noses that they use like satellite dishes. There are about a... more
New method prevents the release of synthetic DNA from genetically modified cells  NEWS MEDICAL · 2 days
The method prevents a gene that encodes a synthetic protein from spreading into the wild and stabilizes it so that it cannot mutate and... more
Environmental DNA proves the expansion of invasive crayfish habitats  SCIENCE DAILY · 2 days
Environmental DNA (eDNA) has successfully proven the presence of invasive crayfish in almost all the small streams around Lake Akan in Japan, suggesting that eDNA analysis is an efficient and... more
Environmental DNA proves the expansion of invasive crayfish habitats  PHYS.ORG · 2 days
Environmental DNA (eDNA) has successfully proven the presence of invasive crayfish in almost all the small streams around Lake Akan in Japan, suggesting that eDNA analysis is an efficient and... more
New rapid DNA test to diagnose chlamydia infection in koalas  PHYS.ORG · 2 days
A new DNA test to detect chlamydia infection in koalas which can be run in the field and gives on-the-spot results within 30 minutes has been developed in... more
Shedding light on the reaction mechanism of PUVA light therapy for skin diseases  SCIENCE DAILY · 3 days
Physical chemists have clarified which chemical reactions take place during PUVA therapy. The therapy involves light-induced damage to the DNA of diseased... more
Lighting up proteins with Immuno-SABER  SCIENCE DAILY · 3 days
Researchers have developed a new DNA-nanotechnology-based approach called Immuno-SABER, that combines the protein targeting specificity of commonly available antibodies with a DNA-based signal-amplification strategy that enables the highly multiplexed visualization of many proteins in the same sample with... more
Century-old salmon-smeared notebooks reveal past bounty of fisheries  Science Magazine · 4 days
DNA analysis of scales stuck to page suggest wild sockeye declines in Canada have been larger than thought more
Scientists uncover mystery of DNA methylation  PHYS.ORG · 4 days
All species mark their DNA with methyl groups. This is done to regulate gene expression, distinguish indigenous DNA from foreign DNA, or to mark old DNA strands during replication. Methylation is carried out by certain enzymes... more
Scientists uncover mystery of DNA methylation  SCIENCE DAILY · 4 days
To a large extent, DNA methylation, which regulates vital cell functions, is still a big mystery to the scientific world. Now,, scientists have developed a method to quickly couple methylation enzymes to their respective methylation pattern.... more
Smart interaction between proteins  PHYS.ORG · 4 days
Very little was known till now about DNA repair by homologous recombination, which is fundamental for human health. Now an ETH research group has for the first time isolated and studied all the key proteins involved in this process, laying... more
Gallstone formation may be driven by neutrophils  NEWS MEDICAL · 4 days
Neutrophils generate sticky webs of DNA called neutrophil extracellular traps (NETs) that act as a “glue” during gallstone formation. more
International study investigates the genetic cause of stuttering  NEWS MEDICAL · 5 days
Researchers need 3,000 Australian stutterers for an international study that is searching for the genes in human DNA which cause stuttering. more
Genetic study suggests humans, not Ice Age, killed off European cave bears  PHYS.ORG · 1 week
A team of researchers affiliated with multiple institutions across Europe has found evidence that suggests humans were responsible for the extinction of cave bears... more
IDT launches high quality, ready-to-use custom oligo pools  NEWS MEDICAL · 1 week
Continuing its mission to advance biological research worldwide, Integrated DNA Technologies has launched oPools Oligo Pools – ready-to-use pools of high quality DNA oligonucleotides (oligos) up to 350 nucleotides in length. more
Extinct Caribbean bird yields DNA after 2,500 years in watery grave  SCIENCE DAILY · 1 week
Scientists have recovered the first genetic data from an extinct bird in the Caribbean, thanks to the remarkably preserved bones of a Creighton's caracara from a... more
Extinct Caribbean bird yields DNA after 2,500 years in watery grave  PHYS.ORG · 1 week
Scientists have recovered the first genetic data from an extinct bird in the Caribbean, thanks to the remarkably preserved bones of a Creighton's caracara from a... more
Immune cells drive gallstone formation  SCIENCE DAILY · 1 week
Sticky meshworks of DNA and proteins extruded by white blood cells called neutrophils act as the glue that binds together calcium and cholesterol crystals during gallstone formation, researchers report. Both genetic and pharmacological approaches that inhibited the formation... more
Moderate to heavy drinking during pregnancy alters genes in newborns, mothers  SCIENCE DAILY · 1 week
Mothers who drink moderate to high levels of alcohol during pregnancy may be changing their babies' DNA, according to a new study. more
New drug shows encouraging survival in pancreatic cancer  SCIENCE DAILY · 1 week
A phase 1 clinical trial testing a new drug in pancreatic cancer had promising initial results, report researchers. The trial looked at AZD1775, an inhibitor designed to block an enzyme called Wee1,... more
DNA tests of UK waters could help catch invasive species early  SCIENCE DAILY · 1 week
Scientists have discovered several artificially introduced species in the coastal waters of southern England, using a technique that could help the early detection of non-native species... more
DNA tests of UK waters could help catch invasive species early  PHYS.ORG · 1 week
A team of scientists from the University of Southampton, Bangor University and the National Oceanography Centre have discovered several artificially introduced species in the coastal waters... more
Cow gut study finds bugs that could up yields  PHYS.ORG · 1 week
Cutting-edge DNA technologies have discovered thousands of bugs in cows' stomachs that could improve meat and dairy production, and keep cattle healthy. more
Rat detective uses DNA to uncover how rats scurry around cities  PHYS.ORG · 1 week
It's dark and I'm parked in an alley near a lopsided compost bin. I have a notepad, binoculars and a lukewarm cup of coffee—everything needed for... more
DNA methylation may influence the effects of aspirin in patients with breast cancer  NEWS MEDICAL · 1 week
Women with a particular DNA feature may live longer if they take aspirin even before they are diagnosed with breast cancer, a... more
Key phosphorus-based molecule for life on Earth may have come from space  PHYS.ORG · 2 weeks
The answer to "How did the first organisms on Earth incorporate the critical element phosphorus?" has been a quandary for researchers, but, University of... more
UAMS Myeloma Center receives $542,486 grant from Leukemia & Lymphoma Society  NEWS MEDICAL · 2 weeks
Brian Walker, Ph.D., with the Myeloma Center at the University of Arkansas for Medical Sciences has received a $542,486, three-year grant from the Leukemia & Lymphoma... more
Study shows how dual DNA barcoding could help improve diagnosis of fungal infections  NEWS MEDICAL · 2 weeks
A new study from The Westmead Institute for Medical Research (WIMR) has demonstrated how dual DNA barcoding could help improve the diagnosis... more
Fish preserve DNA 'memories' far better than humans do  SCIENCE DAILY · 2 weeks
We are all familiar with the common myth that fish have poor memory, but it turns that their DNA has the capacity to hold much more memory than that of... more
Upcycling of proteins protects DNA from parasites  PHYS.ORG · 2 weeks
Of the three billion base pairs in the human genome, less than two percent contain the information encoding the ~20,000 proteins. That is, because at least half of our genetic material originated from selfish... more
Synthetic sequence entanglement augments stability and containment of genetic information in cells  Science Magazine · 2 weeks
In synthetic biology, methods for stabilizing genetically engineered functions and confining recombinant DNA to intended hosts are necessary to cope with natural mutation accumulation... more
A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies  Science Magazine · 2 weeks
TP53, which encodes the tumor suppressor p53, is the most frequently mutated gene in human cancer. The selective pressures shaping its mutational spectrum, dominated... more
Structure elucidation of colibactin and its DNA cross-links  Science Magazine · 2 weeks
Colibactin is a complex secondary metabolite produced by some genotoxic gut Escherichia coli strains. The presence of colibactin-producing bacteria correlates with the frequency and severity of colorectal cancer in humans. However, because... more
Study furthers radically new view of gene control  PHYS.ORG · 2 weeks
In recent years, MIT scientists have developed a new model for how key genes are controlled that suggests the cellular machinery that transcribes DNA into RNA forms specialized droplets called condensates. These... more
Bermuda's baitfish populations  SCIENCE DAILY · 2 weeks
A new study used DNA markers to characterize the genetic diversity of Bermuda's baitfish populations. The island's baitfish were shown to exist in highly mixed populations of up to six different species indicating that individual fish from multiple locations around... more
Guacamole lovers, rejoice! The avocado genome has been sequenced  SCIENCE DAILY · 2 weeks
We now know the DNA of guacamole. Scientists have sequenced the avocado genome, shedding light on the ancient origins of this buttery fruit and laying the groundwork for future improvements... more
Scientists from Vilnius develop cost-effective and faster DNA testing method  NEWS MEDICAL · 2 weeks
DNA or genetic testing is a medical test that identifies changes in chromosomes, genes, or proteins to determine a genetic condition or eliminate the chance of the formation... more
Targeting DNA sequencing for plant biodiversity research  SCIENCE DAILY · 3 weeks
High-throughput sequencing is revolutionizing research in plant evolutionary biology. Using third-generation sequencing technologies, researchers are able to target long fragments of chloroplast DNA to improve genome assembly. Researchers have developed a new method to... more
Targeting DNA sequencing for plant biodiversity research  PHYS.ORG · 3 weeks
Third-generation sequencing (TGS) technologies like the portable MinION sequencer promise to revolutionize biology, but getting there will require tweaking techniques. Particularly, the low output delivered by TGS sequencers means that targeted sequencing approaches will... more
Researchers embrace imperfection to improve biomolecule transport  nanowerk · 3 weeks
While watching the production of porous membranes used for DNA sorting and sequencing, researchers wondered how tiny steplike defects formed during fabrication could be used to improve molecule transport. They found that the defects... more
Researchers embrace imperfection to improve biomolecule transport  PHYS.ORG · 3 weeks
While watching the production of porous membranes used for DNA sorting and sequencing, University of Illinois researchers wondered how tiny steplike defects formed during fabrication could be used to improve molecule transport. They found... more
Scientists crack the code to improve stress tolerance in plants  SCIENCE DAILY · 3 weeks
Epigenetic regulation -- modification of gene expression from the 'outside' -- is an important part of the overall genetic processes within a cell. A group of scientists now... more
Mapping the kinks in faulty DNA  PHYS.ORG · 3 weeks
Here is a challenge for you: copy letter-by-letter, word-for-word a document that is 1,200,000 pages long—that's a stack of paper higher than the Statue of Liberty. And don't make any typos  or miss any punctuation. more
Scientists Sequence RNA of 14,300-Year-Old Wolf Puppy  SCI-NEWS.COM · 3 weeks
An international team of scientists has isolated and sequenced RNA from the permafrost-preserved liver, cartilage and muscle tissue of a 14,300-year-old Pleistocene... more
Scientists crack the code to improve stress tolerance in plants  PHYS.ORG · 3 weeks
In any eukaryotic organism, the DNA in a cell exists not as a loose strand, but as a highly condensed complex that consists of DNA and other proteins... more
DNA origami innovation increases accessibility, lowers cost  nanowerk · 3 weeks
Researchers have developed a faster, cheaper and simpler alternative to typical DNA origami fabrication, increasing the technique's accessibility and potential impact in industry and clinical settings. more
DNA origami innovation increases accessibility, lowers cost  PHYS.ORG · 3 weeks
Researchers have developed a faster, cheaper and simpler alternative to typical DNA origami fabrication, increasing the technique's accessibility and potential impact in industry and clinical settings. more
Chromosome structure inspires intricate works of art  PHYS.ORG · 3 weeks
A collaboration between a Virginia Tech entomology professor, art professor, and computer science professor working in biophysics has resulted in the creation of stunning works of art that can help researchers and the public... more
Unique genetic history of Finnish people offers clues to disease  NEWS MEDICAL · 3 weeks
A new study harnessed the unique genetic history of the people of Finland to identify variations in DNA that might predispose certain individuals to disease, whether or not... more
Protective protein guards against DNA damage and could help target fast growing cancer cells  SCIENCE DAILY · 3 weeks
The discovery that an essential protein plays a protective role during cell division, could open the door to better targeted... more
Finnish people's unique genetic makeup offers clues to disease  SCIENCE DAILY · 3 weeks
A new study harnessed the unique genetic history of the people of Finland to identify variations in DNA that might predispose certain individuals to disease, whether or not they are... more
Stochastic tunneling across fitness valleys can give rise to a logarithmic long-term fitness trajectory  Science Magazine · 3 weeks
Adaptation, where a population evolves increasing fitness in a fixed environment, is typically thought of as a hill-climbing process on... more
Major class of viruses reveals complex origins  SCIENCE DAILY · 3 weeks
A new study examines the evolutionary dynamics of circular Rep-encoding single-stranded (CRESS) DNA viruses. The findings show that this broad class of single-stranded DNA viruses, which infect all three cellular domains of life, have... more
Understanding creation of antibiotic scaffolds could drive new class of antibiotics  NEWS MEDICAL · 3 weeks
Understanding how antibiotic scaffolds are constructed in nature can help scientists prospect for new classes of antibiotics through DNA sequencing and genome mining. more
Skin in balance: Joint forces of polarity and cell mechanics  PHYS.ORG · 3 weeks
The cell polarity protein Par3 controls mechanical changes in the skin and plays an important role in cell division. Malfunction can lead to DNA damages. The balance of... more
First pictures of enzyme that drives new class of antibiotics  PHYS.ORG · 3 weeks
Understanding how antibiotic scaffolds are constructed in nature can help scientists prospect for new classes of antibiotics through DNA sequencing and genome mining. Researchers have used this knowledge... more
Gatekeepers of the genome  PHYS.ORG · 3 weeks
Transcription factors control gene activation in cells. By binding to specific segments of DNA, they enable the blueprints that code for cellular proteins to be produced. But how are such factors themselves regulated? more
Lung cell patches its own DNA on the fly to survive influenza  SCIENCE DAILY · 4 weeks
Scientists have identified one kind of lung cell that can hustle to repair its damaged DNA and survive an attack of the influenza A... more
Discovery could open door to new therapies for Parkinson's, other brain diseases  NEWS MEDICAL · 4 weeks
A small protein previously associated with cell dysfunction and death in fact serves a critical function in repairing breaks in DNA, according to new... more
Komodo dragon genome reveals clues about its evolution  PHYS.ORG · 4 weeks
The Komodo dragons are the largest lizards in the world. These predators weighing up to 200 pounds can detect their prey from up to 7.5 miles away. And although they are cold-blooded,... more
Discovery could lead to new treatments for Parkinson's, other brain diseases  SCIENCE DAILY · 4 weeks
A small protein previously associated with cellular dysfunction and death in fact serves a critical function in repairing breaks in DNA, according to new research. The... more
Team's study reveals details of new DNA repair pathway  PHYS.ORG · 4 weeks
A team of Vanderbilt investigators has discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity. more
New CRISPR tool enhances RNA editing  NEWS MEDICAL · 4 weeks
CRISPR-based tools helped revolutionize the ability to target genetic mutations linked to disease development. Such tools focus on using the enzymes Cas9 and Cas12 to target DNA, and Cas13 to target RNA. Now, scientists used a... more
New CRISPR platform expands the reach of RNA editing to new targets  NEWS MEDICAL · 4 weeks
CRISPR-based tools have revolutionized our ability to target disease-linked genetic mutations. CRISPR technology comprises a growing family of tools that can manipulate genes and... more
Microbial manufacturing: Genetic engineering breakthrough for urban farming  SCIENCE DAILY · 4 weeks
Researchers have developed a new technology that revolutionizes the creation of genetic material, enabling drastically accelerated genetic engineering of microbes that can be used to manufacture chemicals used for urban farming. The... more
Whole-genome sequencing emerges as a key tool for salmonella detection  NEWS MEDICAL · 4 weeks
The world's food supply will become safer as the food industry shifts to high-resolution, whole-genome sequencing – which examines the full DNA of a given organism all at... more
For salmonella detection, genomic tool emerges as a key  SCIENCE DAILY · 4 weeks
The world's food supply will become safer as the food industry shifts to high-resolution, whole-genome sequencing -- which examines the full DNA of a given organism all at once. This... more
Top tools for pinpointing genetic drivers of disease  SCIENCE DAILY · 4 weeks
A new benchmarking study has determined the best analysis tools for identifying errors in a patient's DNA that are responsible for driving disease. Being able to pinpoint these 'genomic rearrangements' is vital... more
Engineers find new way to create single-chain protein nanostructures  PHYS.ORG · 4 weeks
The ancient art of paper folding known as origami is used to make intricate birds or other shapes. Inspired by the work of DNA origami, in which nanostructures are made... more
Revolutionary method could bring us much closer to the description of hyperdiverse faunas  SCIENCE DAILY · 4 weeks
Largely relying on DNA barcoding, rather than traditional practices, a simplified diagnostics method for species description could be the key to revealing... more
'Junk' DNA mutations highly significant in autism and stroke  NEWS MEDICAL · 4 weeks
Non-coding DNA, junk DNA, genetic dark matter – these are all names for the 98% of DNA that doesn’t directly code for proteins but is crucial in regulating protein synthesis.... more
Biochemists streamline construction method for human artificial chromosomes  PHYS.ORG · 4 weeks
For the past 20 years, researchers have been trying to perfect the construction of human artificial chromosomes, or HACs for short. In a paper published today in Cell, Penn researchers describe a... more
Microbial manufacturing: Genetic engineering breakthrough for urban farming  PHYS.ORG · 4 weeks
Researchers at SMART, MIT's research enterprise in Singapore, and National University of Singapore (NUS) have developed a technology that greatly accelerates the genetic engineering of microbes that can be used to manufacture... more
Social amoebae establish a protective interface with their bacterial associates by lectin agglutination  Science Magazine · 4 weeks
Both animals and amoebae use phagocytosis and DNA-based extracellular traps as anti-bacterial defense mechanisms. Whether, like animals, amoebae also use tissue-level barriers... more
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