DNA
Rutgers researchers identify small mutations for AML and MDS through deep DNA sequencing  NEWS MEDICAL · 6 hours
Deep DNA sequencing analysis conducted by Rutgers Cancer Institute of New Jersey investigators examining genomic differences within tumors for prediction of disease... more
Storing data in everyday objects  SCIENCE DAILY · 16 hours
Researchers and an Israeli scientist have discovered a new method for turning nearly any object into a data storage unit. This makes it possible to save extensive data in, say, shirt buttons, water bottles or even the lenses... more
Genomic cut and paste using a class 1 CRISPR system  PHYS.ORG · 20 hours
Almost from the moment DNA was discovered, the ability to fix or remove disease-causing genes in affected patients has been something of a holy grail of medicine. Now... more
Finding the smallest genes could yield outsized benefits  PHYS.ORG · 18 hours
While scientists know of about 25,000 genes that code for biologically important proteins, additional, smaller genes hiding in our DNA may be just as important. But these tiny lines of genetic code... more
CRISPR-resistant viruses build 'safe rooms' to shield genomes from DNA-dicing enzymes  PHYS.ORG · 18 hours
Bacteria and the viruses that infect them are engaged in a molecular arms race as ancient as life itself. Evolution has equipped bacteria with an arsenal... more
'Junk DNA' affects inherited cancer risk  SCIENCE DAILY · 3 days
A person's risk of developing cancer is affected by genetic variations in regions of DNA that don't code for proteins, previously dismissed as 'junk DNA', according to new research. This new study shows that inherited cancer... more
The surprising individuality of microRNAs  PHYS.ORG · 4 days
In order for the instructions contained within a gene to ultimately execute some function in the body, the nucleotides, or letters, that make up the gene's DNA sequence must be "read" and used to produce a messenger RNA... more
Study sheds light on how ‘junk DNA’ affects inherited cancer risk  NEWS MEDICAL · 4 days
A person’s risk of developing cancer is affected by genetic variations in regions of DNA that don’t code for proteins, previously dismissed as ‘junk DNA’, according... more
Scientists identify how damaged DNA molecules are repaired inside the human genome  NEWS MEDICAL · 5 days
A team of scientists has identified how damaged DNA molecules are repaired inside the human genome, a discovery that offers new insights into how... more
What does DNA's repair shop look like? New research identifies the tools  PHYS.ORG · 5 days
A team of scientists has identified how damaged DNA molecules are repaired inside the human genome, a discovery that offers new insights into how... more
New eDNA tool research helps scientists find deep sea corals  PHYS.ORG · 5 days
Curtin University researchers have developed a promising new toolkit for monitoring threatened coral ecosystems by analyzing environmental DNA (eDNA) extracted from waters off the coast of the Cocos... more
How our single-celled relatives package their DNA  PHYS.ORG · 5 days
A group of single-celled organisms organises its DNA in a similar way to higher organisms such as plants, animals, and fungi. However, the way packaged DNA is read out differs between the two related... more
DNA testing for siblings of children with ASD may be predictive of future diagnosis  NEWS MEDICAL · 5 days
One of the key priorities of interventions for autism spectrum disorder (ASD) is starting early, with some evidence showing infants... more
Epigenomic techniques used to fight disease  NEWS MEDICAL · 5 days
Humans differ from one another in many ways, including how they react to disease, because of their DNA blueprint, as well as the difference in the environments they face. These factors combine to make each person... more
Medical News Today: Why scientists are studying hibernation to tackle obesity  MNT · 6 days
New research in hibernating mammals reveals that noncoding DNA may play a role in mechanisms related to obesity control in humans and other animals. more
China raises ethical concern by recreating faces using DNA samples  NEWS MEDICAL · 6 days
Researchers in China are reportedly using blood samples taken from minority groups in an attempt to reconstruct faces from DNA. more
How accumulating useful genes helps older yeast fare better in tougher times  SCIENCE DAILY · 6 days
Researchers have used yeast to learn more about how satellite (extrachromosomal) DNA circles are formed to carry amplified genes, how the gene duplication is... more
China raises ethical concern by re-creating faces using DNA samples  NEWS MEDICAL · 6 days
Researchers in China are reportedly using blood samples taken from minority groups in an attempt to reconstruct faces from DNA. more
Researchers create new technology to help understand how the body battles diseases  NEWS MEDICAL · 6 days
Much remains unknown about diseases and the way our bodies respond to them, in part because the human genome is the complete DNA assembly... more
Highly sensitive epigenomic technology combats disease  PHYS.ORG · 7 days
Much remains unknown about diseases and the way our bodies respond to them, in part because the human genome is the complete DNA assembly that makes each person unique. A Virginia Tech professor and his team... more
Highly sensitive epigenomic technology combats disease  SCIENCE DAILY · 7 days
Much remains unknown about diseases and the way our bodies respond to them, in part because the human genome is the complete DNA assembly that makes each person unique. Researchers have created new technology to help... more
How accumulating useful genes helps older yeast fare better in tougher times  PHYS.ORG · 7 days
Genome amplification, whereby organisms bump up the number of copies of beneficial genes in response to environmental stresses, is implicated in diseases such as... more
All pilsner yeast strains originate from a single yeast ancestor  PHYS.ORG · 7 days
Pilsner yeast, the well-known microorganism that brewers use every year to make hundreds of billions of liters of pilsner and other lagers, came into being 500 years ago... more
Hiring antibodies as nanotechnology builders  nanowerk · 7 days
Researchers recruit antibodies as molecular builders to assemble nanoscale structures made of synthetic DNA. more
Unexpected versatility of an ancient DNA repair factor revealed  NEWS MEDICAL · 1 week
If a bone breaks or a tendon snaps, you know to seek treatment immediately. But your most fragile and precious cellular commodity, chromosomal DNA, breaks with astounding frequency- some estimate... more
75-year old blood-stained microscope slide reveals historical spread of malaria  NEWS MEDICAL · 1 week
DNA from 75-year old eradicated European malaria parasites uncovers the historical spread of one of the two most common forms of the disease, Plasmodium vivax, from Europe to... more
New study uncovers multiple effects of little-known DNA repair protein  NEWS MEDICAL · 1 week
Injury and repair are part of the normal life cycle of any tissue or organ in the human body. However, if macroscopic tears or breaks occur in the... more
1940s blood samples reveal historical spread of malaria  SCIENCE DAILY · 1 week
DNA from 75-year old eradicated European malaria parasites uncovers the historical spread of one of the two most common forms of the disease, Plasmodium vivax, from Europe to the Americas during the... more
1940s blood samples reveal historical spread of malaria  PHYS.ORG · 1 week
DNA from 75-year old eradicated European malaria parasites uncovers the historical spread of one of the two most common forms of the disease, Plasmodium vivax, from Europe to the Americas during the... more
23andMe DNA Testing Kits Up to 50% Off for Cyber Monday  LIVE SCIENCE · 1 week
Go beyond your family tree to uncover ancestry markers in your DNA, with a genetic testing kit that you can use at home. more
Researchers reveal unexpected versatility of an ancient DNA repair factor  PHYS.ORG · 1 week
If a bone breaks or a tendon snaps, you know to seek treatment immediately. But your most fragile and precious cellular commodity, chromosomal DNA, breaks with astounding frequency—some... more
International project aims to sequence the 'DNA' of the Arctic Ocean  PHYS.ORG · 1 week
The University of East Anglia (UEA) is leading a pioneering international project to sequence the DNA of marine microbes in the Arctic Ocean. more
DNA-assembled nanoarchitectures with multiple components in regulated and coordinated motion  Science Magazine · 2 weeks
Coordinating functional parts to operate in concert is essential for machinery. In gear trains, meshed gears are compactly interlocked, working together to impose rotation or translation. In photosynthetic... more
23andMe DNA Testing Kits Up to 50% Off for Black Friday  LIVE SCIENCE · 2 weeks
Go beyond your family tree to uncover ancestry markers in your DNA, with a genetic testing kit that you can use at home. more
Human cohesin compacts DNA by loop extrusion  Science Magazine · 2 weeks
Cohesin is a chromosome-bound multisubunit ATPase complex. Following its loading onto chromosomes, cohesin generates chromosome loops to regulate chromosome functions. It has been suggested that cohesin organizes the genome via loop extrusion, but direct... more
Coordinating the removal of RNA-DNA hybrids  PHYS.ORG · 2 weeks
Two research teams led by Professors Brian Luke and Helle Ulrich at the Institute of Molecular Biology have deciphered how two enzymes, RNase H2 and RNase H1, are coordinated to remove RNA-DNA hybrid structures from chromosomes.... more
Durable multitransgene expression in vivo using systemic, nonviral DNA delivery  Science Magazine · 2 weeks
Recombinant adeno-associated virus (AAV) vectors are transforming therapies for rare human monogenic deficiency diseases. However, adaptive immune responses to AAV and its limited DNA insert capacity, restrict their... more
A conserved ATP- and Scc2/4-dependent activity for cohesin in tethering DNA molecules  Science Magazine · 2 weeks
Sister chromatid cohesion requires cohesin to act as a protein linker to hold chromatids together. How cohesin tethers chromatids remains poorly understood. We have... more
Scientists now know what DNA's chaperone looks like  PHYS.ORG · 2 weeks
It's long been known that the proteins that package DNA, like students at a high school dance, require a chaperone. But what exactly that guardian looks and acts like has been a... more
Discovering hidden plant medicines on your doorstep  PHYS.ORG · 2 weeks
EI is part of the global effort to sequence the DNA all of the known species of animals, plants and fungi on earth, known as the Earth BioGenome Project. Contributing to the UK arm... more
Few things to know before buying at-home genetic testing kits  NEWS MEDICAL · 2 weeks
At-home genetic testing kits, also known as direct-to-consumer or lab-to-consumer DNA tests, are growing in popularity -; especially as holiday gifts. more
Once hidden cellular structures emerge in fight against viruses  PHYS.ORG · 2 weeks
New University of Arizona-led research has revealed the structure and function of one of bacteria's latest strategies in the fight against viruses: a fleet of highly organized enzymes that provide... more
Self-assembling system uses magnets to mimic specific binding in DNA  SCIENCE DAILY · 2 weeks
Physicists are using the binding power of magnets to design self-assembling systems that potentially can be created in nanoscale form. more
Discovery in C. difficile biology opens new window to developing treatments for dangerous infections  NEWS MEDICAL · 2 weeks
A process called sporulation that helps the dangerous bacterium Clostridium difficile (C. difficile) to survive inhospitable conditions and spread is... more
Self-assembling system uses magnets to mimic specific binding in DNA  nanowerk · 2 weeks
Researchers are using the binding power of magnets to design self-assembling systems that potentially can be created in nanoscale form. more
Structurally designed DNA star creates ultra-sensitive test for dengue virus  nanowerk · 2 weeks
By folding snippets of DNA into the shape of a five-pointed star using structural DNA nanotechnology, researchers have created a trap that captures Dengue virus as it floats... more
New discovery in C. difficile biology could lead to treatments for dangerous infections  PHYS.ORG · 2 weeks
A process called sporulation that helps the dangerous bacterium Clostridium difficile (C. difficile) to survive inhospitable conditions and spread is regulated by... more
New highly sensitive test for dengue virus developed using DNA star  NEWS MEDICAL · 2 weeks
Researchers have developed a new method for detecting and destroying the dengue virus that could be adapted for other viruses. more
Structurally designed DNA star creates ultra-sensitive test for dengue virus  PHYS.ORG · 2 weeks
By folding snippets of DNA into the shape of a five-pointed star using structural DNA nanotechnology, researchers have created a trap that captures Dengue virus as it floats... more
Enzyme toolkit makes biotechnology globally accessible  PHYS.ORG · 2 weeks
In 2016, Lenshina Agbor was working on her master's thesis in Cameroon, analyzing the DNA of a parasite that causes malaria in pregnant women. She imported the enzymes needed for her research from Europe, but struggled... more
DNA-modulated liquid droplets may explain how prion proteins clump  NEWS MEDICAL · 2 weeks
Researchers at the Federal University of Rio de Janeiro, in Brazil, have identified that the interaction between prion proteins and DNA may be behind the formation of protein amyloid aggregates... more
Tiny devices made of DNA detect cancer with fewer false alarms  SCIENCE DAILY · 3 weeks
A new cancer-detecting tool uses tiny circuits made of DNA to identify cancer cells by the molecular signature on their surface. The circuits work by attaching... more
Filaments that structure DNA  SCIENCE DAILY · 3 weeks
Researchers discover how outside stimuli drive the formation and reorganization of the cytoskeleton in the nucleus of mammalian cells. more
Tiny devices made of DNA detect cancer with fewer false alarms  PHYS.ORG · 3 weeks
A new cancer-detecting tool uses tiny circuits made of DNA to identify cancer cells by the molecular signatures on their surface. more
The filaments that structure DNA  PHYS.ORG · 3 weeks
They play a leading role not only in muscle cells: Actin filaments are one of the most abundant proteins in all mammalian cells. The filigree structures form an important part of the cytoskeleton and locomotor system. Cell biologists... more
A deep learning-based model DeepSpCas9 to predict SpCas9 activity  PHYS.ORG · 3 weeks
In a new report on Science Advances, Hui Kwon Kim and interdisciplinary researchers at the departments of Pharmacology, Electrical and Computer Engineering, Medical Sciences, Nanomedicine and Bioinformatics in the Republic... more
DNA repeats—the genome's dark matter  PHYS.ORG · 3 weeks
Expansions of DNA repeats are very hard to analyze. A method developed by researchers at the Max Planck Institute for Molecular Genetics in Berlin allows for a detailed look at these previously inaccessible regions of the genome. It... more
Groundbreaking cohesin study describes the molecular motor that folds the genome  PHYS.ORG · 3 weeks
New insights into the process of DNA looping have changed old perspectives about how the genome is organized within cells. Discoveries by IMP researchers have now... more
Extra DNA scooped up alongside cancer-causing genes helps drive tumor growth  NEWS MEDICAL · 3 weeks
One of the ways a cancer-causing gene works up enough power to turn a normal cell into a cancer cell is by copying itself over and... more
Non-coding DNA located outside chromosomes may help drive glioblastoma  SCIENCE DAILY · 3 weeks
According to a new study, extra DNA scooped up and copied alongside cancer-causing genes helps keep tumors going -- elements that could represent new drug targets for brain tumors and... more
DNA loop extrusion by human cohesin  Science Magazine · 3 weeks
Eukaryotic genomes are folded into loops and topologically-associating domains (TADs), which contribute to chromatin structure, gene regulation and recombination. These structures depend on cohesin, a ring-shaped DNA-entrapping ATPase complex which has been proposed to form loops... more
Unraveling gene expression  PHYS.ORG · 3 weeks
The DNA of a single cell is two to three meters long end-to-end. To fit in the nucleus and function correctly, DNA is packaged around specialized proteins. These DNA-protein complexes are called nucleosomes, and they are a small part of... more
Not so selfish after all: Key role of transposable elements in mammalian evolution  PHYS.ORG · 3 weeks
The human genome contains 4.5 million copies of transposable elements (TEs), so-called selfish DNA sequences capable of moving around the genome through... more
Doughnut-shaped circles of ecDNA provide tumor cells with a malignant twist  NEWS MEDICAL · 3 weeks
Deoxyribonucleic acid or DNA encodes information, not only in its sequence but also in its shape. more
'Doughnut-Shaped' DNA Makes Cancer More Aggressive  LIVE SCIENCE · 3 weeks
"DNA conveys information not only in its sequence but also in its shape," the authors said. more
Vicious circles: Ring-shaped DNA provides cancer cells with a malignant twist  SCIENCE DAILY · 3 weeks
Researchers describe how circular extrachromosomal DNA in cancer cells boosts aggressiveness and resistance to therapies. more
Mechanisms of nuclear content loading to exosomes  Science Magazine · 3 weeks
Exosome cargoes are highly varied and include proteins, small RNAs, and genomic DNA (gDNA). The presence of gDNA suggests that different intracellular compartments contribute to exosome loading, resulting in distinct exosome subpopulations. However, the... more
CTF, DELopen jointly offer unique opportunities to neurofibromatosis research community  NEWS MEDICAL · 3 weeks
The Children's Tumor Foundation, an innovative and global neurofibromatosis (NF) research foundation announced today a collaboration with DELopen, a DNA-encoded library technology platform sponsored by WuXi AppTec, a... more
Mitochondrial mixing mechanism critical for sperm production in mice  PHYS.ORG · 3 weeks
Mitochondria, often thought of as the powerhouses of cells, are just one part of a larger living thing, but they are unique among cellular structures in that they have their... more
From origin of life to materials genomics  nanowerk · 3 weeks
The origin of early life and the basic building blocks such as DNA and RNA have been hypothesized to have resulted due to accumulation of precursors within hydrothermal vents. The thermal gradients result in... more
Tracking inheritance of human mitochondrial DNA  PHYS.ORG · 3 weeks
New insight into how genetic information stored in human mitochondria is passed from one generation to the next could have important implications for genetic counseling of women planning pregnancies, according to a study by researchers at... more
Gene therapy: Development of new DNA transporters  nanowerk · 3 weeks
Scientists have developed new delivery vehicles for future gene therapies. They are using artificial fats to transport DNA into cells. more
Rare DNA variants linked to sudden cardiac death  NEWS MEDICAL · 3 weeks
Sudden cardiac death affects 220,000 U.S. adults annually, most of whom have no prior symptoms of a heart issue. more
DNA may hold the clue to protecting endangered species  PHYS.ORG · 4 weeks
A new method for analyzing DNA collected from waterways which can help identify endangered bird species has been developed with the help of researchers from The University of Western Australia. more
Early DNA lineages shed light on the diverse origins of the contemporary population  SCIENCE DAILY · 4 weeks
A new genetic study demonstrates that, at the end of the Iron Age, Finland was inhabited by separate and differing populations, all... more
Lichens are way younger than scientists thought  SCIENCE DAILY · 4 weeks
Lichens -- a combo of fungus and algae -- can grow on bare rocks, so scientists thought that lichens were some of the first organisms to make their way onto land from the water,... more
eDNA reveals where endangered birds of a feather flock together  PHYS.ORG · 4 weeks
For the first time, Australian scientists have shown that environmental DNA (eDNA) can be used to detect the presence of an endangered bird species simply by collecting a... more
A potential new way to diagnose male infertility and pharmaceutical treatment options  SCIENCE DAILY · 4 weeks
New research has discovered infertile men have identifiable patterns of epigenetic molecules or biomarkers attached to their sperm DNA that aren't present in fertile... more
Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions  NEWS MEDICAL · 4 weeks
One might think that the primary cause of most genetically linked diseases comes from mutations in coding DNA -- alterations in coding... more
DNA data offers scientific look at 500 years of extramarital sex in Western Europe  SCIENCE DAILY · 4 weeks
Researchers have put DNA evidence together with long-term genealogical data to explore questions of biological fatherhood on a broad scale... more
DNA data offers scientific look at 500 years of extramarital sex in Western Europe  PHYS.ORG · 4 weeks
These days it's easy to resolve questions about paternity with over-the-counter test kits. Now, researchers have put DNA evidence together... more
Observing changes in the chirality of molecules in real time  PHYS.ORG · 4 weeks
Some molecules can exist in two mirror-image forms, similar to our hands. Although such so-called enantiomers have almost identical physical properties, they are not the same. The fact... more
Researchers unravel protective properties of telomere t-loops  SCIENCE DAILY · 4 weeks
Loops at the ends of telomeres play a vital protective role preventing damage to chromosomes, according to new research. The study showed how the winding and unwinding of 't-loops' at the end of telomeres... more
Predicting evolution: Not just 'survival of the fittest'  SCIENCE DAILY · 4 weeks
A new method of 're-barcoding' DNA allows scientists to track rapid evolution in yeast. The approach has implications for the prediction of dominant viral strains. more
The post-PAM interaction of RNA-guided spCas9 with DNA dictates its target binding and dissociation  Science Magazine · 4 weeks
Cas9 is an RNA-guided endonuclease that targets complementary DNA for cleavage and has been repurposed for many biological usages. Cas9... more
Leukemia type B cell can transform into a macrophage through epigenetic changes  NEWS MEDICAL · 4 weeks
All the tissues of our body have the same DNA, but they perform very different functions and have very different aspects. more
DNA Just One of More Than 1 Million Possible 'Genetic Molecules,' Scientists Find  LIVE SCIENCE · 4 weeks
Scientists used a computer program to uncover more than 1 million molecules that could potentially store genetic information, just like DNA. more
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