DNA
To repair DNA damage, plants need good contractors  SCIENCE DAILY · 12 hours
Researchers report which genes are turned on or off, and in which order, to orchestrate the cellular processes required to protect and repair the genome in response to DNA damage. The research... more
CRISPR joins battle of the bulge, fights obesity without edits to genome  SCIENCE DAILY · 15 hours
A weighty new study shows that CRISPR therapies can cut fat without cutting DNA. Researchers describe how a modified version of CRISPR was used... more
To repair DNA damage, plants need good contractors  PHYS.ORG · 14 hours
When a building is damaged, a general contractor often oversees various subcontractors—framers, electricians, plumbers and drywall hangers—to ensure repairs are done in the correct order and on time. more
New techniques better determine how ancient viral DNA influences human genes  SCIENCE DAILY · 17 hours
New laboratory techniques can identify which of our genes are influenced by DNA snippets that are left behind in our genetic code by viruses. more
Neanderthal genes give clues to human brain evolution  SCIENCE DAILY · 16 hours
A distinctive feature of modern humans is our round (globular) skulls and brains. Researchers report that present-day humans who carry particular Neanderthal DNA fragments have heads that are slightly less rounded, revealing... more
Monitoring the environment with artificial intelligence  PHYS.ORG · 18 hours
Microorganisms perform key functions in ecosystems, and their diversity reflects the health of their environment. However, they are still largely under-exploited in current biomonitoring programs because they are difficult to identify. Researchers from the University of... more
Monitoring the environment with artificial intelligence  SCIENCE DAILY · 17 hours
Microorganisms perform key functions in ecosystems and their diversity reflects the health of their environment. Researchers use genomic tools to sequence the DNA of microorganisms in samples, and then exploit this considerable amount of data with... more
Corn domestication took some unexpected twists and turns  SCIENCE-NEWS · 17 hours
A DNA study challenges the idea people fully tamed maize in Mexico before the plant spread. more
Team invents method to shrink objects to the nanoscale  PHYS.ORG · 17 hours
MIT researchers have invented a way to fabricate nanoscale 3-D objects of nearly any shape. They can also pattern the objects with a variety of useful materials, including metals, quantum... more
Why modern humans have round heads  Science Magazine · 19 hours
Researchers find genes linked to head shape—by tracking traces of Neanderthal DNA in living people more
Neandertal genes shed light on unique aspects of the modern human brain  PHYS.ORG · 20 hours
A characteristic feature of modern humans is the unusually round skull and brain, in contrast to the elongated shape seen in other human species.... more
New discovery will improve the safety and predictability of CRISPR  NEWS MEDICAL · 20 hours
Scientists have discovered a simple set of rules that can be used to precisely predict how DNA will be modified by the CRISPR gene editing technique. more
New techniques better determine how ancient viral DNA influences human genes  PHYS.ORG · 20 hours
New laboratory techniques can identify which of our genes are influenced by DNA snippets that are left behind in our genetic code by viruses, a new... more
50 years ago, armadillos hinted that DNA wasn’t destiny  SCIENCE-NEWS · 24 hours
Nine-banded armadillos have identical quadruplets. But the youngsters aren’t identical enough, and scientists 50 years ago could not figure out why. more
DNA study shows stethoscopes loaded with bacteria, including staphylococcus  SCIENCE DAILY · 2 days
Stethoscopes carried by health care practitioners are loaded with diverse bacteria, including some that can cause healthcare-associated infections, according to a study. The research also reviewed the effectiveness of cleaning... more
DNA analysis finds that stethoscopes used in the ICU are teaming with bacteria  NEWS MEDICAL · 2 days
Researchers have found that stethoscopes carried by healthcare practitioners in an intensive care (ICU) setting are loaded with a wide range of... more
When less is more: A promising approach for low-cell-number epigenomic profiling  PHYS.ORG · 2 days
Scientists at Kyushu University and Tokyo Institute of Technology in Japan have developed a technique that enables analysis of DNA-protein interactions using very small numbers of... more
Using Gold Nanoparticles to Rapidly Detect Cancer DNA  SCI-NEWS.COM · 3 days
Using as little as 1 picogram of purified DNA sample (think 2.5 trillion times lighter than a penny), scientists at... more
When less is more: A promising approach for low-cell-number epigenomic profiling  SCIENCE DAILY · 3 days
Scientists have developed a technique that enables analysis of DNA-protein interactions using very small numbers of cells, ranging from 100 to 1,000. Their method could capture... more
DNA find: Tiny wallaby the last living link to extinct giant kangaroos  PHYS.ORG · 4 days
A QUT-led collaboration with University of Adelaide reveals that Australia's pint-sized banded hare-wallaby is the closest living relative of the giant short-faced kangaroos which... more
Silicosis is on the rise, but is there a therapeutic target?  SCIENCE DAILY · 6 days
Researchers have identified a key mechanism of lung inflammation induced by silica exposure, which leads to silicosis, an incurable disease. Their study in mice and patients... more
Oldest ever traces of the plague found in Falköping  PHYS.ORG · 7 days
In a 5,000 year old grave outside Falköping, scientists have found the oldest traces of the plague bacterium's DNA in the world. An international research team including archaeologists from the... more
Functionally diverse type V CRISPR-Cas systems  Science Magazine · 1 week
Type V CRISPR-Cas systems are distinguished by a single RNA-guided RuvC domain-containing effector, Cas12. Although effectors of subtypes V-A (Cas12a) and V-B (Cas12b) have been studied in detail, the distinct domain architectures and diverged RuvC sequences... more
A DNA methylation reader complex that enhances gene transcription  Science Magazine · 1 week
DNA methylation generally functions as a repressive transcriptional signal, but it is also known to activate gene expression. In either case, the downstream factors remain largely unknown. By using comparative... more
An ancient strain of plague may have led to the decline of Neolithic Europeans  SCIENCE DAILY · 1 week
Researchers have identified a new strain of Yersinia pestis, the bacteria that causes plague, in DNA extracted from 5,000-year-old human... more
Researchers Find First Ever Evidence for Epigenetics in Archaea  SCI-NEWS.COM · 1 week
A team of scientists from the University of Nebraska-Lincoln and the University of California, Santa Cruz, has found... more
An ancient strain of plague may have led to the decline of Neolithic Europeans  PHYS.ORG · 1 week
A team of researchers from France, Sweden, and Denmark have identified a new strain of Yersinia pestis, the bacteria that... more
Study reveals how the absence of Dna2 enzyme affects chromosome instability  NEWS MEDICAL · 1 week
Cells have in place a number of mechanisms to protect the integrity of the genome, including processes that repair mistakes that may occur during DNA replication. more
Possible alterations in the DNA involved in cancer  SCIENCE DAILY · 1 week
The study shows the role of the protein PIF1, capable of undoing different structures in these molecules. These molecules contain the instructions that allow cells to function correctly, so that when there... more
Scientists reveal how DNA damage leads to cancer and hereditary diseases  NEWS MEDICAL · 1 week
Scientists revealed how DNA damage influences mutations. Turned out that its contribution to mutagenesis was underestimated and many of the inheritance mutations are caused not by... more
Medical News Today: Universal 10-minute cancer test in sight  MNT · 1 week
Cancer cells have a unique pattern of chemical tags on their DNA, which differs from that of healthy cells and could serve as the basis for a universal test. more
Without Dna2, genes can jump into DNA breaks  PHYS.ORG · 1 week
Cells have in place a number of mechanisms to protect the integrity of the genome, including processes that repair mistakes that may occur during DNA replication. The enzyme Dna2 participates in DNA... more
Controlling immune response expands the possibilities of therapeutic nucleic acid technologies  nanowerk · 1 week
The idea has been around for a while that selected segments of RNA or DNA could be used therapeutically to affect gene or cell function. The... more
Researchers discover mechanism disrupting CRISPR-Cas9 gene editing  PHYS.ORG · 1 week
The discovery of CRISPR-Cas9 has made gene editing very easy. Unfortunately, the molecular tool has recently been found to be less precise than previously assumed. It can lead to unwanted mutations in a cell's... more
Researchers take a step forward with a study of molecules of DNA  NEWS MEDICAL · 1 week
Researchers from the Andalusian center for Molecular Biology and regenerative Medicine and from the University of Seville have taken a step forward with a... more
Bacterial infections may contribute to far more cancers than previously thought, shows study  NEWS MEDICAL · 1 week
The Institute of Human Virology at the University of Maryland School of Medicine announced today the discovery that DnaK, a protein of... more
FDA takes significant step forward in driving development of novel genetic tests  NEWS MEDICAL · 1 week
The U.S. Food and Drug Administration today took a significant step forward in driving the efficient development of novel diagnostic technologies that scan a... more
A bacterial protein is found to promote cancer  SCIENCE DAILY · 1 week
Researchers have discovered that DnaK, a protein of the bacterium mycoplasma, interferes with the mycoplasma-infected cell's ability to respond to and repair DNA damage, a known origin of cancer. more
Natural selection in the womb can explain health problems in adulthood  SCIENCE DAILY · 1 week
Conditions encountered in the womb can have life-long impact on health. Scientists previously assumed this is because embryos respond to adverse conditions by programming their gene... more
Advances in gene therapy for inherited blood disorders  NEWS MEDICAL · 1 week
Gene therapy holds a lot of promise in medicine. If we could safely alter our own DNA, we might eliminate diseases our ancestors passed down to us. more
Cancer DNA Binds to Gold. That Could Lead to New Cancer Blood Test.  LIVE SCIENCE · 1 week
Researchers have discovered a curious difference between the DNA from cancer cells and that from healthy cells, and this finding could lead... more
A universal DNA nano-signature for cancer  PHYS.ORG · 1 week
Researchers from the University of Queensland's Australian Institute for Bioengineering and Nanotechnology (AIBN) have discovered a unique nano-scaled DNA signature that appears to be common to all cancers. more
Cancer DNA signature will revolutionize point-of-care diagnostics  NEWS MEDICAL · 1 week
Researchers have developed a potentially game-changing new technology that could revolutionize cancer point-of-care (POC) diagnostics. more
Innovative DNA recovery techniques could help victims catch rapists in Kenya  PHYS.ORG · 1 week
A huge global health challenge is physical and sexual violence against women and girls, affecting more than one third of all women globally. more
Simple yet powerful model predicts DNA organization  PHYS.ORG · 1 week
Scientists often try to understand important processes in the cell by interfering and observing what happens. But often the cell just dies. more
In death, Lonesome George reveals why giant tortoises live so long  SCIENCE DAILY · 2 weeks
Genetic analysis of DNA from Lonesome George and samples from other giant tortoises of the Galapagos -- which can live more than 100 years in captivity... more
Scientists develop nanoscale tweezers that can move freely within cells  NEWS MEDICAL · 2 weeks
Researchers have developed nanoscale “tweezers” that can extract cellular components such as DNA, proteins, and organelles, without causing damage or bursting the cell. more
Nanoscale tweezers can perform single-molecule 'biopsies' on individual cells  SCIENCE DAILY · 2 weeks
Using electrical impulses, the 'tweezers' can extract single DNA, proteins and organelles from living cells without destroying them. more
Nanoscale tweezers can perform single-molecule 'biopsies' on individual cells  PHYS.ORG · 2 weeks
Using electrical impulses, the 'tweezers' can extract single DNA, proteins and organelles from living cells without destroying them. more
Nanoscale tweezers can perform single-molecule 'biopsies' on individual cells  nanowerk · 2 weeks
Using electrical impulses, the tweezers can extract single DNA, proteins and organelles from living cells without destroying them. more
Not in the DNA: Epigenetics discovered in single-celled archaea  SCIENCE DAILY · 2 weeks
Researchers have reported the first experimental evidence of epigenetics in the single-celled organisms known as archaea. The simplicity of archaea -- combined with the fact that their cells resemble eukaryotes'... more
Study uncovers how HIV DNA is blocked from entering the cell nucleus  NEWS MEDICAL · 2 weeks
Multiple components of the nuclear pore complex and nuclear import machinery enable a protein called human myxovirus resistance 2 (MX2) to inhibit HIV-1 infection,... more
Screening the human future: YouTube, persuasion and genetically engineered children  PHYS.ORG · 2 weeks
On Sunday, Nov. 25, the scientist He Jiankui claimed the birth of the world's first genetically engineered children: twins, created by IVF, their DNA altered at fertilization. Changes... more
Dads, not just moms, can pass along mitochondrial DNA  SCIENCE-NEWS · 2 weeks
Data from three families suggest that in rare cases children can inherit mitochondria from their fathers. more
AMSBIO introduces new high yield cell-free protein expression kit  NEWS MEDICAL · 2 weeks
AMSBIO introduces ALiCE- a new high yield cell-free protein expression system. Cell-free protein expression is today used by protein chemists to quickly produce small amounts of proteins when screening DNA... more
The long and short of CDK12  MIT · 2 weeks
A new study linking RNA processing to DNA repair may open new avenues to cancer therapy. more
New Mainz-based Collaborative Research Center aims to explore DNA repair and genome stability  NEWS MEDICAL · 2 weeks
From January 1, 2019, the German Research Foundation will be funding the new Collaborative Research Center 1361 on Regulation of DNA Repair... more
Shape-shifting protein protects bacteria from invaders  SCIENCE DAILY · 2 weeks
Researchers have discovered how bacteria manage to destroy enemy DNA, while keeping their own genetic material safe. more
How HIV DNA is blocked from entering the cell nucleus  SCIENCE DAILY · 2 weeks
Multiple components of the nuclear pore complex and nuclear import machinery enable a protein called human myxovirus resistance 2 (MX2) to inhibit HIV-1 infection, according to a new... more
Single-cell multiomics sequencing and analyses of human colorectal cancer  Science Magazine · 2 weeks
Although genomic instability, epigenetic abnormality, and gene expression dysregulation are hallmarks of colorectal cancer, these features have not been simultaneously analyzed at single-cell resolution. Using optimized single-cell multiomics sequencing together... more
How HIV DNA is blocked from entering the cell nucleus  PHYS.ORG · 2 weeks
Multiple components of the nuclear pore complex and nuclear import machinery enable a protein called human myxovirus resistance 2 (MX2) to inhibit HIV-1 infection, according to a study... more
Editorial: The (somewhat obvious) ethical problems with creating gene-edited babies  PHYS.ORG · 2 weeks
It has long been a scientific dream: to inoculate people against terrible diseases before they're born. Now a team of doctors based in China has dangled that possibility... more
China halts research team's work on gene-edited babies  CBC · 2 weeks
China's government orders a halt to work by a medical team that claims it helped make the world's first gene-edited... more
China halts work by team on gene-edited babies  ABC NEWS · 2 weeks
A group of leading scientists has declared that it's still too soon to try making permanent changes to DNA that can be inherited by future generations, as a Chinese researcher claims to... more
Mechanism safeguarding unique epigenome of oocytes and maternal fertility  PHYS.ORG · 2 weeks
In mammals, females have a limited supply of oocytes. Oocytes have a unique epigenome with approximately half the DNA methylation of sperm, and the most terminally differentiated somatic cells. Until... more
DNA mutations in healthy and leukemic blood stem cells do not differ, shows research  NEWS MEDICAL · 2 weeks
Researchers from the Princess Máxima Center for Pediatric Oncology have shown that the number of mutations in healthy and leukemic... more
Scientists: World still isn't ready for gene-edited babies  ABC NEWS · 2 weeks
A group of leading scientists has declared that it's still too soon to try making permanent changes to DNA that can be inherited by future generations, as a Chinese researcher claims to... more
Healthy blood stem cells have as many DNA mutations as leukemic cells  SCIENCE DAILY · 2 weeks
Researchers have shown that the number of mutations in healthy and leukemic blood stem cells does not differ. Rather the location of the mutations... more
Audi’s e-tron GT concept is an all-electric sedan with some Porsche DNA  TechCrunch · 2 weeks
Audi is making room in its electric future for more than SUVs or crossovers. After a string of teasers, the German automaker finally unveiled... more
[Editors' Choice] DNA folding for renal rescue  Science Magazine · 2 weeks
DNA origami nanostructures offer an alternative therapeutic for kidney targeting and treatment of acute kidney injury in mice. more
Sharing benefits of digitized DNA  PHYS.ORG · 2 weeks
Today, scientists can sift through quadrillions of genetic sequences in open-access databases, searching (free-of-charge) for new ways to engineer crops, develop medicines or even create synthetic organisms. But a controversial proposal that aims to share the benefits of... more
Gene-Edited Twins in China Still Face Risk of HIV Infection  Gadgets 360 · 2 weeks
Twin girls whose DNA was altered as part of a controversial effort in China to make them resistant to HIV infection could still contract the virus that causes... more
How antibiotics spread resistance  PHYS.ORG · 2 weeks
Bacteria can become insensitive to antibiotics by picking up resistance genes from the environment. Unfortunately for patients, the stress response induced by antibiotics activates competence in microorganisms, the ability to take up and integrate foreign DNA. Microbiologists from the University... more
Discovery about DNA twists could be crucial in development of new antibiotics  NEWS MEDICAL · 2 weeks
DNA replication is vital to all lifeforms, but in some organisms, it can be prevented by twists in the DNA sequence, called 'supercoils'. If... more
DNA with a twist: Discovery could further antibiotic drug development  SCIENCE DAILY · 2 weeks
Scientists reveal how a 'molecular machine' in bacterial cells prevents fatal DNA twisting, which could be crucial in the development of new antibiotic treatments. more
How antibiotics help spread resistance  SCIENCE DAILY · 2 weeks
Bacteria can become insensitive to antibiotics by picking up resistance genes from the environment. Unfortunately for patients, the stress response induced by antibiotics activates competence, the ability of cells to take up and integrate foreign DNA, in microorganisms.... more
Largest study of CRISPR-Cas9 mutations creates prediction tool for gene editing  SCIENCE DAILY · 2 weeks
The largest study of CRISPR action to date has developed a method to predict the exact mutations CRISPR-Cas9 gene editing can introduce to a cell. Researchers... more
Largest study of CRISPR-Cas9 mutations creates prediction tool for gene editing  PHYS.ORG · 2 weeks
The largest study of CRISPR action to date has developed a method to predict the exact mutations CRISPR-Cas9 gene editing can introduce to a cell. Researchers... more
Microbiologists uncover how antibiotics help spread resistance  NEWS MEDICAL · 2 weeks
Bacteria can become insensitive to antibiotics by picking up resistance genes from the environment. Unfortunately for patients, the stress response induced by antibiotics activates competence, the ability of cells to take up and integrate foreign DNA,... more
First ancient DNA from mainland Finland reveals origins of Siberian ancestry in region  SCIENCE DAILY · 2 weeks
A new study shows that the genetic makeup of northern Europe traces back to migrations from Siberia that began at least 3,500... more
A fresh look at winter footprints: Environmental DNA improves tracking of rare carnivores  SCIENCE DAILY · 2 weeks
A new project shows that animal footprints contain enough DNA for species identification. The study extracted DNA from snow samples collected within... more
A fresh look at winter footprints: Environmental DNA improves tracking of rare carnivores  PHYS.ORG · 2 weeks
An innovative new project has discovered that animal footprints contain enough DNA to allow for species identification. Scientists have traditionally relied on... more
Ancient DNA shows the Sámi and Finns share identical Siberian genes  PHYS.ORG · 2 weeks
The first study on the DNA of the ancient inhabitants of Finland has been published, with results indicating that an abundance of genes reached Finland all... more
WATCH: American professor investigated for involvement in genetically edited babies  ABC NEWS · 2 weeks
Rice University bioengineering professor Dr. Michael Deem is being investigated by the university for his participation in a controversial gene-editing technology used to manipulate the DNA of twins. more
Dads (Not Just Moms) Can Pass on Mitochondrial DNA, According to Provocative New Study  LIVE SCIENCE · 2 weeks
It's long been thought that people inherit mitochondrial DNA exclusively from their mothers. But a provocative new study suggests otherwise. more
Study: Measuring and monitoring tumor DNA can help reveal early melanoma growth  NEWS MEDICAL · 2 weeks
Researchers at the Johns Hopkins Kimmel Cancer Center say they have added to evidence that measuring and monitoring tumor DNA that naturally circulates in... more
Role of circulating tumor DNA to detect early melanoma growth  SCIENCE DAILY · 2 weeks
Researchers say they have added to evidence that measuring and monitoring tumor DNA that naturally circulates in the blood of melanoma patients can not only reliably help reveal... more
CRISPRGene EditingGeneticsBiology
Nanoscale tweezers can perform single-molecule 'biopsies' on individual cells
PHYS.ORG
Study shows mitochondrial DNA can be passed through fathers – what does this mean for genetics?
PHYS.ORG
New tricks of TALEs: Discovery of a new principle of gene regulation by molecular displacement
PHYS.ORG
Is the future of dog health in a DNA test?
PHYS.ORG
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