Diseases
Melting reveals drug targets in a living organism  SCIENCE DAILY · 30 minutes
Developing new medicines and understanding how they target specific organs often gives a crucial advantage in the fight against human diseases. An international team has developed a technology to systematically identify drug... more
Bioactive peptide helps prevent new cavities, heal existing ones  NEWS MEDICAL · 31 minutes
Cavities, or dental caries, are the most widespread non-communicable disease globally, according to the World Health Organization. Having a cavity drilled and filled at the dentist's office can be painful,... more
Cancer: Faster drug discovery to hit 'undruggable' targets  SCIENCE DAILY · 32 minutes
Medicines made from coiled protein fragments could provide a new handle on hard-to-treat diseases like cancer, but they are difficult to design. But a new technique could change that. more
A heart-healthy protein from bran of cereal crop  SCIENCE DAILY · 32 minutes
Foxtail millet is an annual grass grown widely as a cereal crop in parts of India, China and Southeast Asia. Milling the grain removes the hard outer layer, or bran, from the... more
Preventing, healing tooth decay with a bioactive peptide  SCIENCE DAILY · 32 minutes
Cavities, or dental caries, are the most widespread non-communicable disease globally, according to the World Health Organization. Having a cavity drilled and filled at the dentist's office can be painful, but untreated... more
Most rehabilitating sea turtles with infectious tumors don't survive  SCIENCE DAILY · 1 hour
Fibropapillomatosis (FP) is the most significant infectious disease affecting sea turtle populations worldwide. FB leads to tumors on the turtles' eyes, flippers and internal organs and is widespread in warmer... more
Single-cell morphology encodes metastatic potential  Science Magazine · 2 hours
A central goal of precision medicine is to predict disease outcomes and design treatments based on multidimensional information from afflicted cells and tissues. Cell morphology is an emergent readout of the molecular underpinnings of a cell’s functions and,... more
Deficient histone H3 propionylation by BRPF1-KAT6 complexes in neurodevelopmental disorders and cancer  Science Magazine · 2 hours
Lysine acetyltransferase 6A (KAT6A) and its paralog KAT6B form stoichiometric complexes with bromodomain- and PHD finger-containing protein 1 (BRPF1) for acetylation of histone H3... more
Isothermal digital detection of microRNAs using background-free molecular circuit  Science Magazine · 2 hours
MicroRNAs, a class of transcripts involved in the regulation of gene expression, are emerging as promising disease-specific biomarkers accessible from tissues or bodily fluids. However, their accurate quantification from biological... more
Dense hydroxyl polyethylene glycol dendrimer targets activated glia in multiple CNS disorders  Science Magazine · 2 hours
Poor transport of neuropharmaceutics through central nervous system (CNS) barriers limits the development of effective treatments for CNS disorders. We present the facile synthesis... more
[Research Articles] The IDH-TAU-EGFR triad defines the neovascular landscape of diffuse gliomas  Science Magazine · 2 hours
Gliomas that express the mutated isoforms of isocitrate dehydrogenase 1/2 (IDH1/2) have better prognosis than wild-type (wt) IDH1/2 gliomas. However, how these mutant (mut)... more
Only one lab in China can safely handle the new coronavirus  LIVE SCIENCE · 2 hours
As an escalating viral outbreak unfolds in China, only one lab in the country meets the required biosafety standards needed to study the new disease. more
Johns Hopkins researchers warn of new infectious diseases and death due to global warming  NEWS MEDICAL · 2 hours
The Journal of Clinical Investigation recently published "Viewpoint" articles by Johns Hopkins University School of Medicine professors who warn that... more
Decline in advanced stage cancer diagnoses following health insurance expansion  NEWS MEDICAL · 2 hours
Advanced stage cancer diagnoses declined following health insurance expansion in Massachusetts, likely due to increased access to screening and diagnostic services that identified cancers earlier, according to new... more
Preventing, healing tooth decay with a bioactive peptide  PHYS.ORG · 2 hours
Cavities, or dental caries, are the most widespread non-communicable disease globally, according to the World Health Organization. Having a cavity drilled and filled at the dentist's office can be painful, but untreated... more
Federal government backs Ohio on Down syndrome abortion law  ABC NEWS · 2 hours
The federal government is taking Ohio's side in a lawsuit over the state law prohibiting doctors from performing abortions based on a fetal diagnosis of Down syndrome more
New roles found for Huntington's disease protein  SCIENCE DAILY · 2 hours
A research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington's Disease. Using genetic mouse models, they have discovered that... more
Cognitive function in people with mental illness  SCIENCE DAILY · 2 hours
A study has shown few differences in the profiles of genes that influence cognition between people with schizophrenia, bipolar disorder and the general population. This surprising finding could provide new insights into therapies designed... more
Researchers identify potential way to halt age-related macular degeneration  NEWS MEDICAL · 3 hours
Researchers have successfully treated age-related macular degeneration in mice after finding an unexpected link between the two main forms of the blinding eye disease, the leading cause of vision loss... more
Children born to mothers with gestational diabetes and preeclampsia at risk for higher BMI  NEWS MEDICAL · 4 hours
Childhood obesity is a growing problem in the United States. For children, obesity is defined as having a body mass... more
Most rehabilitating sea turtles with infectious tumors don't survive  PHYS.ORG · 5 hours
Caused by a herpesvirus, fibropapillomatosis (FP) is the most significant infectious disease affecting sea turtle populations worldwide. It is widespread in warmer climates like Florida, where almost 70 percent of... more
Researchers slash pre-drug screening time from years to days  PHYS.ORG · 6 hours
Researchers at Ben-Gurion University of the Negev (BGU) and The Hebrew University of Jerusalem (HU) have developed a powerful tool that will streamline and accelerate the development of disease therapies,... more
Study sheds light on mechanisms that underlie a rare genetic condition  NEWS MEDICAL · 6 hours
A team of researchers at CHU Sainte-Justine and Université de Montréal has shed light on the mechanisms that underlie a rare genetic condition by creating the... more
Melting reveals drug targets in a living organism  PHYS.ORG · 7 hours
Developing new medicines and understanding how they target specific organs often gives a crucial advantage in the fight against human diseases. An international team led by researchers at the European Molecular Biology... more
Research paves the way to improved treatment for complex blood disorders  NEWS MEDICAL · 7 hours
Nearly 1.6 billion people worldwide suffer from anemia, and for the first time new research points to how resistance emerges to the drug dexamethasone used to... more
A heart-healthy protein from bran of cereal crop  PHYS.ORG · 8 hours
Foxtail millet is an annual grass grown widely as a cereal crop in parts of India, China and Southeast Asia. Milling the grain removes the hard outer layer, or bran, from the... more
A new book on antioxidant foods that prevent or treat chronic diseases  NEWS MEDICAL · 14 hours
A search using medical data bases reveals that hundreds of meta-analysis papers conducted with tens of millions of people worldwide have confirmed clinically the... more
Potential Parkinson's treatment effectively targets a specific group of brain cells  NEWS MEDICAL · 14 hours
Scientists have discovered that a non-invasive technique which could one day be used to treat Parkinson's disease, can successfully target a highly specific group of brain... more
Study: Psychiatric challenges in young girls with autism are linked to larger amygdala  NEWS MEDICAL · 16 hours
Preschool-age girls with autism spectrum disorder (ASD) face greater challenges with emotional and behavioral problems than similar age boys with ASD. more
USA confirms 1st Wuhan coronavirus case  NEWS MEDICAL · 17 hours
The United States has its first confirmed case of a mysterious and new virus, the Wuhan coronavirus, which originated in China and has killed nine people and sickened hundreds since it first appeared, the Centers for... more
Fat cells can sense light, not getting enough raises risk of metabolic diseases  NEWS MEDICAL · 17 hours
All life forms need sunlight to survive and not getting enough may impact health and well-being. There is a growing body of... more
Case Western researchers suggest potential Alzheimer's breakthrough  NEWS MEDICAL · 17 hours
Researchers at the Case Western University School of Medicine say they have identified a previously unknown gene and associated protein which could potentially be suppressed to slow the advance of Alzheimer's disease. more
International researchers confirm potential inhibitors to combat glioblastoma  NEWS MEDICAL · 17 hours
After diagnosis, only thirty percent of glioblastoma (an aggressive brain cancer) patients have survived more than two years. more
Research team identifies new roles for Huntington's Disease protein  NEWS MEDICAL · 20 hours
A Duke University research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington's Disease. more
Coconut oil increases bad cholesterol  NEWS MEDICAL · 20 hours
Elevated low-density lipoprotein (LDL) or bad cholesterol level is an established risk factor for developing cardiovascular disease (CVD), including heart disease, hypertension, and stroke. Contrary to current claims that coconut oil can benefit cardiovascular health, a new study... more
Scientists develop capsule shell composition for enzyme needed to treat phenylketonuria  NEWS MEDICAL · 20 hours
IKBFU scientists developed the composition of the capsule shell for the enzyme needed in the treatment of a hereditary disease called "phenylketonuria". more
George Mason University researchers receive $314,000 to design better vaccines  NEWS MEDICAL · 20 hours
George Mason University's Aarthi Narayanan, Associate Professor, College of Science and the National Center for Biodefense and Infectious Disease, and Remi Veneziano, Assistant Professor, Volgenau School of Engineering,... more
Cyberbullying may amplify symptoms of depression and PTSD  NEWS MEDICAL · 21 hours
Cyberbullying had the impact of amplifying symptoms of depression and post-traumatic stress disorder in young people who were inpatients at an adolescent psychiatric hospital, according to a new study published in the... more
Discovery of potent immune cell that can destroy multiple types of cancer  NEWS MEDICAL · 21 hours
The immune system is the body’s defense against harmful pathogens that may enter the body. Immune cells, such as white blood cells and macrophages... more
Cardiac and visual degeneration compensated by taurine supplement  NEWS MEDICAL · 22 hours
Our genome consists of 20,000 genes, all of which may be capable of triggering disease. It is estimated that there are 7,000 unknown genes that cause recessive genetic diseases resulting from mutations... more
New genetic test to predict and prevent vision loss from glaucoma  NEWS MEDICAL · 1 day
Researchers have identified 107 genes that increase a person's risk of developing the eye disease glaucoma, and now developed a genetic test to detect those at... more
Study reveals new mechanism involved in the pathogenesis of IBD  NEWS MEDICAL · 1 day
Inflammatory bowel disease is a category of refractory inflammatory disease, of which ulcerative colitis and Crohn's disease are the main types. more
Zebrafish teach researchers more about atrial fibrillation  SCIENCE DAILY · 1 day
Genetic research in zebrafish has surprised the researchers behind the study. The results have the potential to change the prevalent perception of the cardiac disorder atrial fibrillation. more
Depression treatment must also restore integrity of the blood-brain barrier  NEWS MEDICAL · 1 day
To better treat people with depression, not only must we treat the neurons affected by the disease, but we must also restore the integrity of the barrier that... more
Biophysicists shed light on the structure, functioning mechanism of CysLT receptors  NEWS MEDICAL · 1 day
Biophysicists from the MIPT Center for Molecular Mechanisms of Aging and Age-Related Diseases have teamed up with colleagues from Canada, the U.S., Japan, France, and Germany... more
Raman spectroscopy can be used to diagnose the state of thrombocytes in cardiovascular patients  NEWS MEDICAL · 1 day
A team of scientists from Immanuel Kant Baltic Federal University used Raman spectroscopy to study the thrombocytes of patients with... more
Faster drug discovery to hit 'undruggable' targets  PHYS.ORG · 1 day
Medicines made from coiled protein fragments could provide a new handle on hard-to-treat diseases like cancer, but they are difficult to design. But a new technique, developed at the University of Michigan, could change... more
Human exposure to aluminum linked to familial Alzheimer's disease  SCIENCE DAILY · 1 day
A new study supports a growing body of research that links human exposure to aluminum with Alzheimer's disease (AD). Researchers found significant amounts of aluminum content in brain tissue from... more
Antiviral compound from banana plants shows potential for clinical use against influenza  NEWS MEDICAL · 1 day
What keeps most infectious disease researchers up at night aren't infamous viruses like Ebola. Instead, influenza, commonly known as the flu, continues to be... more
Enterprise Therapeutics publishes open access paper on novel approach to treat cystic fibrosis  NEWS MEDICAL · 1 day
Enterprise Therapeutics Ltd, a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of patients suffering... more
New technology systematically identifies drug targets in living animals  NEWS MEDICAL · 1 day
Developing new medicines and understanding how they target specific organs often gives a crucial advantage in the fight against human diseases. more
First robotic coronary angioplasties with R-One successfully completed in Germany  NEWS MEDICAL · 1 day
Robocath, a company that designs, develops and commercializes cardiovascular robotic systems for the treatment of vascular diseases, today announces it has successfully completed its first robotic coronary angioplasties... more
Diagnosed with dementia, she documented her wishes. They said no.  NEWS MEDICAL · 1 day
When she worked on the trading floor of the Chicago Board Options Exchange, long before cellphone calculators, Susan Saran could perform complex math problems in her head. Years... more
Collaborative project to address the local opioid epidemic  NEWS MEDICAL · 1 day
The University of Arizona is partnering with the Tucson Police Department, CODAC Health, Recovery & Wellness, and Pima County as part of a three-year, $1.47 million Substance Abuse and Mental Health Services... more
SITESEEKER to be used for Otsuka’s therapeutics discovery programs  NEWS MEDICAL · 1 day
PhoreMost will deploy its in-house expertise and next-generation phenotypic screening platform, SITESEEKER, in disease-relevant pathways nominated by Otsuka. more
EXPLORER scanner captures real-time videos of blood flow and heart function  NEWS MEDICAL · 2 days
Positron Emission Tomography, or PET scanning, a technique for tracing metabolic processes in the body, has been widely applied in clinical diagnosis and research spanning physiology,... more
Medical News Today: Heart health: Are women getting incorrect treatment?  MNT · 2 days
A new review investigates sex differences in cardiometabolic disorders. The authors conclude that women are more at risk of receiving the wrong treatment. more
Certain enzymes implicated in diseases like cancer also destroy each other  NEWS MEDICAL · 2 days
Like motley bandits, certain enzymes implicated in cancer and other diseases also annihilate each other. A new study reveals details of their mutual foils in the... more
Alarming link between marijuana and increased heart risk  NEWS MEDICAL · 2 days
Marijuana use is rising steadily across the US as more and more states enact laws making it a legal recreational and medicinal agent. However, a new study underlines the fact that this... more
Enzymes that cannibalize each other and promote cancer  NEWS MEDICAL · 2 days
A new study to be published this week in the journal The Proceedings of the National Academy of Sciences in the week of January 20, 2020. shows that certain human enzymes play... more
New uses for old medicines  NEWS MEDICAL · 2 days
It turns out that in the rush to invent new drugs to treat cancers, scientists may have overlooked some obvious possibilities of existing drugs currently being used for other diseases. A new study says that therapies for diabetes,... more
While promoting diseases like cancer, these enzymes also cannibalize each other  PHYS.ORG · 2 days
Like motley bandits, certain enzymes implicated in cancer and other diseases also annihilate each other. A new study reveals details of their mutual foils in the... more
Ultrasound could help reduce the use of drugs for patients with rheumatoid arthritis  NEWS MEDICAL · 2 days
A research group led by the physician Christian Dejaco is investigating circumstances under which patients may stop taking medication for rheumatoid arthritis... more
Patient enrollment in potentially life-extending clinical trials is low  NEWS MEDICAL · 2 days
Patient enrollment in clinical trials as the first course of treatment after cancer diagnosis is low, despite the fact that enrollment may increase life expectancy, according to researchers at Penn... more
Researchers solve protein structures to fight asthma  PHYS.ORG · 2 days
Biophysicists from the MIPT Center for Molecular Mechanisms of Aging and Age-Related Diseases have teamed up with colleagues from Canada, the U.S., Japan, France, and Germany to shed light on the structure and functioning... more
Disarming bacteria with mucus and phages  PHYS.ORG · 2 days
Millions of people are treated with antibiotics each year for infections or as a preventative measure. The Centers for Disease Control and Prevention reports that at least 2.8 million people are infected with antibiotic-resistant bacteria each... more
Online campaign to save malnourished lions at Sudan park  PHYS.ORG · 3 days
Online calls grew Sunday to help save five "malnourished and sick" African lions held at a park in Sudan's capital, with some demanding the creatures be shifted to a better... more
17 new cases reported in China's viral pneumonia outbreak  ABC NEWS · 3 days
Seventeen more people in central China have been diagnosed with a new form of viral pneumonia that has killed two patients and placed other countries on alert more
China reports 17 new cases in viral pneumonia outbreak  ABC NEWS · 4 days
Seventeen more people in central China have been diagnosed with a new form of viral pneumonia that has killed two patients and placed other countries on alert more
Scurvy is still found in Canada  NEWS MEDICAL · 5 days
Scurvy, the debilitating condition remembered as a disease of pirates, is still found in Canada. more
Researchers identify how certain areas of the brain respond to ADHD drug  NEWS MEDICAL · 5 days
Attention-deficit hyperactivity disorder is a neurobiological disorder characterized by symptoms of hyperactivity, inattention and impulsivity. more
Ingestible medical devices can be broken down with light  PHYS.ORG · 5 days
A variety of medical devices can be inserted into the gastrointestinal tract to treat, diagnose, or monitor GI disorders. Many of these have to be removed by endoscopic surgery once... more
US to screen airline passengers from China for new illness  ABC NEWS · 5 days
U.S. health officials have announced they will begin screening airline passengers from central China for a new virus that is making people sick more
Psychedelics could help treat trauma-related disorders  NEWS MEDICAL · 5 days
Clinical trials suggest treatment that involves psychedelics can be more effective than psychotherapy alone. more
CALCR neurons may influence long-term control of food intake and body weight  NEWS MEDICAL · 5 days
Ever eaten something, gotten sick and then didn't want to eat that food again because of how it made you feel? That's because a... more
Activation of a distinct genetic pathway can slow the progress of metastatic breast cancer  SCIENCE DAILY · 5 days
Activation of the BMP4 signalling pathway presents a new therapeutic strategy to combat metastatic breast cancer, a disease that has... more
Chemist proposes new method for synthesizing precursors for Parkinson's drugs  PHYS.ORG · 5 days
A chemist from RUDN University has proposed a new method for the synthesis of secondary propargylamine used to create antidepressants, drugs for Parkinson's disease and other neurodegenerative diseases,... more
Sanitary care by social ants shapes disease outcome  PHYS.ORG · 5 days
Sanitary care in ants to fight disease is known to improve the wellbeing of the colony, yet it has been unclear how social disease defense interferes with pathogen competition inside the individual... more
Amblyopia treatment may need to be revised, research suggests  NEWS MEDICAL · 5 days
When University of California, Irvine neurobiologist Carey Y.L. Huh, Ph.D., set her sights on discovering more about amblyopia, she brought personal insight to her quest. As a child, Huh was... more
Researchers visualize molecular organization of TNFα receptor molecules  NEWS MEDICAL · 5 days
Whether a sick cell dies, divides, or travels through the body is regulated by a sophisticat-ed interplay of signal molecules and receptors on the cell membrane. more
America's most widely consumed oil causes genetic changes in the brain  SCIENCE DAILY · 5 days
New research shows soybean oil not only leads to obesity and diabetes, but could also affect neurological conditions like autism, Alzheimer's disease, anxiety, and depression. more
Sanitary care by social ants shapes disease outcome  SCIENCE DAILY · 5 days
Sanitary care in ants to fight disease is known to improve the wellbeing of the colony, yet it has been unclear how social disease defense interferes with pathogen competition inside the individual... more
15 percent of people in the US are physically inactive, CDC report says  NEWS MEDICAL · 6 days
The new year may have motivated people to jot down their fitness goals, but a new country-wide map of inactivity in the... more
Genetically engineered mosquitoes halt Dengue spread  NEWS MEDICAL · 6 days
A new study published in the journal PLOS Pathogens in January 2020 reports the development of mosquitoes that have been genetically modified to resist infection by several types of the dengue virus. This is the first... more
NHS partners with pharma giant to trial a twice-a-year jab to lower cholesterol levels  NEWS MEDICAL · 6 days
Cardiovascular disease, including heart disease and stroke, are among the top killers worldwide. Ischemic heart disease and stroke are the... more
Physicists design 'super-human' red blood cells to deliver drugs to specific targets  SCIENCE DAILY · 6 days
A team of physicists from McMaster University has developed a process to modify red blood cells so they can be used to distribute drugs... more
Making sense of the self  SCIENCE DAILY · 6 days
Interoception is the awareness of our physiological states. But precisely how the brain calculates and reacts to this information remains unclear. Neuroscientists now demonstrate how the insular cortex orchestrates the process. The work represents the first steps toward... more
Scientists discover how B-cells in tumor cells promote a favorable immunotherapy response  NEWS MEDICAL · 6 days
The white blood cells are potent fighters that protect the body against foreign invaders, including pathogens and cancer cells. Scientists have found that the... more
Falling risk of heart disease among survivors of child cancer since the 1970s  SCIENCE DAILY · 6 days
There has been a measurable decline in serious heart conditions among adult survivors of childhood cancer since the 1970s, finds a new... more
Untreated sleep apnea can increase the risk of dying from heart disease  NEWS MEDICAL · 6 days
February is American Heart Month. Did you know that sleep apnea impacts heart health? According to the American Academy of Sleep Medicine, nearly 30... more
Study provides new insights into small acidic protein linked to Parkinson's disease  NEWS MEDICAL · 6 days
Research by University at Buffalo biologists is providing new insights into alpha-synuclein, a small acidic protein associated with Parkinson's disease. more
UK-wide trial aims to find treatments that can slow or reverse MND  NEWS MEDICAL · 6 days
Hundreds of people living with motor neurone disease are being invited to take part in one of the UK's most comprehensive clinical trials in... more
Greater medical care needed for older adults with untreated sleep apnea  NEWS MEDICAL · 6 days
Obstructive sleep apnea is a common and costly medical condition leading to a wide range of health risks such as cardiovascular disease, stroke, depression, diabetes and... more
3D structure of DNA is 'rewired' in hormone-resistant ER+ breast cancers  NEWS MEDICAL · 6 days
Epigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatment for ER+ breast cancer, which... more
A secreted signature of aging cells  SCIENCE DAILY · 6 days
Senescent cells undergo an irreversible and permanent arrest of cell division and are hallmarks of both the aging process and multiple chronic diseases. Senescent cells -- and more importantly the factors they secrete, known collectively as... more
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