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Erectile dysfunction is red flag for silent early cardiovascular disease
SCIENCE DAILY Despite decades long prevention and treatment efforts, cardiovascular (CV) disease continues to be the leading cause of death worldwide. Early detection of CV disease can allow for interventions... 19 hours
‘Sushi-like’ nanodiscs provide structural snapshots of misfolding proteins
NEWS MEDICAL When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers, including University of Michigan biophysicists, have obtained a structural snapshot of these proteins when they... 20 hours
Higher blood sugar in early pregnancy raises baby's heart-defect risk
SCIENCE DAILY Higher blood sugar early in pregnancy raises the baby's risk of a congenital heart defect, even among mothers who do not have diabetes, according to a study. 1 day
Nanodiscs catch misfolding proteins red-handed
SCIENCE DAILY When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers have obtained a structural snapshot of these proteins when they are most toxic, detailing them down to the atomic level. 1 day
Unveiling massive numbers of cancer-related urinary-microRNA candidates via nanowires
Science Magazine Analyzing microRNAs (miRNAs) within urine extracellular vesicles (EVs) is important for realizing miRNA-based, simple, and noninvasive early disease diagnoses and timely medical checkups. However, the inherent difficulty in collecting dilute... 1 day
Extracellular vesicles can be used to effectively delay progression of kidney damage
NEWS MEDICAL Researchers have demonstrated for the first time that extracellular vesicles - tiny protein-filled structures - isolated from amniotic fluid stem cells (AFSCs) can be... 1 day
Higher blood sugar during first trimester of pregnancy increases child's risk of congenital heart defect
NEWS MEDICAL Higher blood sugar early in pregnancy raises the baby's risk of a congenital heart defect, even among mothers who do... 1 day
Vitamin deficiency in later life
SCIENCE DAILY One in two persons aged 65 and above has suboptimal levels of vitamin D in the blood and one in four older adults has suboptimal vitamin B12 levels. 1 day
vergecast fcc kills net neutrality the imac pro arrives and t mobile buys layer3 tv Vergecast: FCC kills net neutrality, the iMac Pro arrives, and T-Mobile buys Layer3 TV
THE VERGE The Vergecast three-piece is back together, with Nilay... 1 day
Revealing the best-kept secrets of proteins
SCIENCE DAILY A new approach for identifying important undiscovered functions of proteins has been revealed by a team of researchers. 1 day
Food-induced anaphylaxis common among children despite adult supervision
SCIENCE DAILY At least a third of reactions in children with food-induced anaphylaxis to a known allergen occur under adult supervision, according to a new study. The findings reveal that inadvertent exposures to a... 1 day
so long aim we ll miss you So long, AIM, we'll miss you
THE VERGE AOL shut down AOL Instant Messenger, aka AIM, today after 20 years of existence. AOL announced the news in October, saying the service was... 1 day
Earwax like ice cores—unlocking the past hidden in whale earplugs
PHYS.ORG Farzaneh Mansouri's future data collectors are cruising around oceans worldwide, following blooms of productivity and accumulating decades of information—all in their earwax. Mansouri, an environmental scientist at Baylor... 1 day
uber eats couriers in europe to be offered free accident and sickness insurance Uber Eats couriers in Europe to be offered free accident and sickness insurance
TechCrunch  Uber has announced it’s launching a free insurance package for... 1 day
New research linking cancer-inhibiting proteins to cell antennae
PHYS.ORG Danish researchers have just presented a previously unknown mechanism that inhibits the ability of cells to develop into cancer cells. Their findings have important implications for the understanding of how cancer starts,... 1 day
Many food-induced anaphylaxis cases in children occur under adult supervision
NEWS MEDICAL At least a third of reactions in children with food-induced anaphylaxis to a known allergen occur under adult supervision, according to a new study led by AllerGen researchers... 2 days
Nutritional scientists call on Canadian government to impose stricter limits on unhealthy foods
NEWS MEDICAL University of Toronto nutritional scientists are leading a study with national experts calling on the Canadian government to outlaw junk food marketing to children,... 2 days
SOMA Xbox One review: Horror that remains intriguing years later
Windows Central SOMA is a survival horror game which immerses you deep beneath the ocean. The first-person perspective of SOMA limits visibility so you never know what might be lurking... 2 days
Computational strategies overcome obstacles in peptide therapeutics development
PHYS.ORG New computational strategies reported this week in Science might help realize the promise of peptide-based drugs. Peptides are similar to protein molecules, but differ in their smaller size, structure and functions. 2 days
life s building blocks observed in spacelike environment Life’s Building Blocks Observed in Spacelike Environment
ASTRO WATCH Where do the molecules required for life originate? It may be that small organic molecules first appeared on earth and were later... 2 days
Scientists develop new approach to identify important undiscovered functions of proteins
PHYS.ORG In the bustling setting of the cell, proteins encounter each other by the thousands. Despite the hubbub, each one manages to selectively interact with just the... 2 days
Cracking the code of coenzyme Q biosynthesis
SCIENCE DAILY Coenzyme Q (CoQ) is a vital cog in the body's energy-producing machinery, a kind of chemical gateway in the conversion of food into cellular fuel. But six decades removed from its discovery, scientists still... 2 days
RALF4/19 peptides interact with LRX proteins to control pollen tube growth in Arabidopsis
Science Magazine The communication of changes in the extracellular matrix to the interior of the cell is crucial for a cell’s function. The extracellular... 2 days
The ER membrane protein complex is a transmembrane domain insertase
Science Magazine Insertion of proteins into membranes is an essential cellular process. The extensive biophysical and topological diversity of membrane proteins necessitates multiple insertion pathways that remain incompletely defined. Here,... 2 days
Comprehensive computational design of ordered peptide macrocycles
Science Magazine Mixed-chirality peptide macrocycles such as cyclosporine are among the most potent therapeutics identified to date, but there is currently no way to systematically search the structural space spanned by such compounds. Natural proteins do... 2 days
An extra sugar protects
Science Magazine 2 days
Eudicot plant-specific sphingolipids determine host selectivity of microbial NLP cytolysins
Science Magazine Necrosis and ethylene-inducing peptide 1–like (NLP) proteins constitute a superfamily of proteins produced by plant pathogenic bacteria, fungi, and oomycetes. Many NLPs are cytotoxins that facilitate microbial infection... 2 days
Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation
Science Magazine Reversible detyrosination of α-tubulin is crucial to microtubule dynamics and functions, and defects have been implicated in cancer, brain disorganization, and cardiomyopathies. The identity of the tubulin tyrosine carboxypeptidase (TCP)... 2 days
What keeps stem cells in their undifferentiated state?
SCIENCE DAILY A special cluster of proteins helps unwind DNA during cell division and plays a key role in keeping stem cells in their immature state, scientists have discovered. This study also points to... 2 days
Medical News Today: Ten causes of epigastric pain
MNT Epigastric pain is felt in the upper abdomen, below the ribcage but above the intestines. Learn about the possible causes, including GERD and indigestion. 2 days
Ten causes of epigastric pain
MNT Epigastric pain is felt in the upper abdomen, below the ribcage but above the intestines. Learn about the possible causes, including GERD and indigestion. 2 days
Synthetic protein packages its own genetic material and evolves
SCIENCE DAILY Scientists have created computationally designed protein assemblies, that display some functions normally associated with living things, in the search for ways to transport therapeutic cargo into specific types of cells... 2 days
Scientists develop new, rapid pipeline for antimicrobials
SCIENCE DAILY Antibodies are proteins produced by the human immune system to ward off foreign invaders. Our bodies mount this defense rapidly, especially if they have seen the invader before, producing the needed antibody within days... 2 days
Hydrogen production: protein environment makes catalyst efficient
SCIENCE DAILY The interaction of protein shell and active center in hydrogen-producing enzymes is crucial for the efficiency of biocatalysts. A team specifically analyzed the role of hydrogen bonds in certain enzymes from green algae, the... 2 days
DNA: Supercoiling pushes molecular handcuffs along chromatin fibres
SCIENCE DAILY As it squeezes down the chromatin fiber, the cohesin protein complex extrudes a growing loop of DNA -- a bit like the quick-lacing system of trail-running shoes. But what is powering the... 2 days
Sugary-drink warning labels may help decrease obesity and overweight prevalence
NEWS MEDICAL Labels that warn people about the risks of drinking soda and other sugar-sweetened beverages can lower obesity and overweight prevalence suggests a new Johns Hopkins Bloomberg School of... 2 days
Medical News Today: All you need to know about fat-soluble vitamins
MNT Learn all about the four types of fat-soluble vitamins: A, D, E, and K. We look at dietary sources of each and their role within the... 2 days
Putting algae and seaweed on the menu could save our seafood
PHYS.ORG If we have to feed 9.8 billion people by 2050, food from the ocean will have to play a major role. Ending hunger and malnutrition while... 2 days
Lab-grown meat could let humanity ignore a serious moral failing
PHYS.ORG Lab-grown meat is being hailed as the solution to the factory farming of animals. The downside of factory farming for the cows, chickens and pigs themselves is obvious... 2 days
Designer proteins that package genetic material could help deliver gene therapy
PHYS.ORG If you've ever bought a new iPhone, you've experienced good packaging. 2 days
Protein environment makes catalyst efficient for hydrogen production
PHYS.ORG The interaction of protein shell and active centre in hydrogen-producing enzymes is crucial for the efficiency of biocatalysts. A team from Ruhr-Universität Bochum and the Max Planck Institute for Chemical Energy Conversion... 2 days
Science explains the colour of your Christmas
PHYS.ORG When we think of Christmas, what colour comes to mind? For most people, that colour is probably red. Even Santa himself is red. It's a colour reminiscent of family, good food, Santa and his... 2 days
BigH1—the key histone for male fertility
PHYS.ORG Researchers in the Chromatin Structure and Function Lab at the Institute for Research in Biomedicine (IRB Barcelona) have identified the histone BigH1 as a key protein in stem cell differentiation to male sex cells. Histones are... 2 days
FDA announces new approach for sharing updates on antibiotics, antifungal drugs to physicians
NEWS MEDICAL Today the U.S. Food and Drug Administration is announcing a new approach to get critical updates regarding antibiotics and antifungal drugs to... 3 days
Lactic acid bacteria can offer protection against subtypes of influenza A virus
NEWS MEDICAL Lactic acid bacteria, commonly used as probiotics to improve digestive health, can offer protection against different subtypes of influenza A virus, resulting in reduced... 3 days
Tailor-made protein combats several kinds of pathogenic bacteria
NEWS MEDICAL As resistance to existing antibiotics increases, new approaches to serious bacterial infections are needed. Now researchers at Lund University in Sweden, together with colleagues at the University of Massachusetts Medical School in the US,... 3 days
Protein structure could pave way for effective drugs to treat cystic fibrosis
NEWS MEDICAL Biochemists at the University of Zurich have used cryo-electron microscopy to determine the detailed architecture of the chloride channel TMEM16A. This protein is a... 3 days
Microbes help turn Greek yogurt waste into fuel
SCIENCE DAILY Consumers across the world enjoy Greek yogurt for its taste, texture, and protein-packed punch. Reaching that perfect formula, however, generates large volumes of food waste in the form of liquid whey. Now... 3 days
The toxic sugar tree: Mapping the evolutionary history of a cancerous sugar gene
PHYS.ORG Around two million years ago, a genetic change occurred that differentiated humans from most other primates that both protected humans from diseases,... 3 days
Three papers help to crack the code of coenzyme Q biosynthesis
PHYS.ORG Coenzyme Q (CoQ) is a vital cog in the body's energy-producing machinery, a kind of chemical gateway in the conversion of food into cellular fuel. But... 3 days
Researchers trace the potato's origins, learn about its untapped potential
PHYS.ORG The comfort food we know and love today as the potato was domesticated between 8,000 and 10,000 years ago from a wild species native to the Andes Mountains... 3 days
Protein structure could unlock new treatments for cystic fibrosis
SCIENCE DAILY Biochemists have used cryo-electron microscopy to determine the detailed architecture of the chloride channel TMEM16A. This protein is a promising target for the development of effective drugs to treat cystic... 3 days
[Editors' Choice] A diet pill for critical illness weakness?
Science Magazine The serotoninergic drug Lorcaserin rescued motor neuron electrophysiological abnormalities in an animal model of critical illness–induced weakness. 3 days
[Research Articles] Urine lipoarabinomannan glycan in HIV-negative patients with pulmonary tuberculosis correlates with disease severity
Science Magazine An accurate urine test for pulmonary tuberculosis (TB), affecting 9.6 million patients worldwide, is critically needed for surveillance... 3 days
Lactic acid bacteria can protect against influenza a virus
SCIENCE DAILY Lactic acid bacteria, commonly used as probiotics to improve digestive health, can offer protection against different subtypes of influenza A virus, resulting in reduced weight loss after virus infection and... 3 days
Protein structure could unlock new treatments for cystic fibrosis
PHYS.ORG Biochemists at the University of Zurich have used cryo-electron microscopy to determine the detailed architecture of the chloride channel TMEM16A. This protein is a promising target for the development of... 3 days
Anti-stress compounds provide new treatment approach for diabetes and obesity
NEWS MEDICAL For the first time, scientists from the Max Planck Institute of Psychiatry in Munich could prove that a stress protein found in muscle has a diabetes promoting effect.... 3 days
Microbes help turn Greek yogurt waste into fuel
PHYS.ORG Consumers across the world enjoy Greek yogurt for its taste, texture, and protein-packed punch. Reaching that perfect formula, however, generates large volumes of food waste in the form of liquid whey. Now... 3 days
Medical News Today: Cancer: Some immune cells found to give tumors a helping hand
MNT A study shows that neutrophils, a type of immune cell, work with the protein Snail to maintain a microenvironment that... 3 days
Scientists develop new artificial ovary prototype
SCIENCE DAILY Researchers have taken important steps towards creating transplantable artificial ovaries. Once successful, these could be of value to women struggling with infertility or cancer patients who cannot conceive after undergoing radiation or chemotherapy. The research team... 3 days
Anti-stress compound reduces obesity and diabetes
SCIENCE DAILY For the first time, scientists could demonstrate that a stress protein found in muscle has a diabetes promoting effect. This finding could pave the way to a completely new treatment approach. 3 days
Cellular self-digestion process triggers autoimmune disease
SCIENCE DAILY Autophagy allows cells to degrade and recycle their cellular components. Researchers have now demonstrated that the autophagy machinery in certain immune cells leads to the immune system attacking the central nervous system. The researchers are using... 3 days
Modulating immune responses
SCIENCE DAILY The protein Roquin plays a key role in the regulation of immune reactions. Researchers have now uncovered details of the mechanism by which it controls the function of regulatory T cells in the adaptive arm of the immune system. 3 days
Specially designed protein fights several species of bacteria
SCIENCE DAILY As resistance to existing antibiotics increases, new approaches to serious bacterial infections are needed. Now researchers have investigated one such alternative. 3 days
New insights into mosquito sex protein could provide strategies to control diseases
NEWS MEDICAL If you thought the sex lives of humans were complicated, consider the case of the female Aedes aegypti mosquito, bringer of Zika, dengue, and... 3 days
Synchrony of waves: Collective dynamics
SCIENCE DAILY Researchers report that endocytosis, which was previously thought to be a random process, actually occurs in a coordinated manner through collective dynamics. The work showed how a major endocytic pathway mediated by the protein clathrin, was found to... 3 days
Nanotexturing creates bacteria-killing spikes on stainless steel surfaces
SCIENCE DAILY By using an electrochemical etching process on a common stainless steel alloy, researchers have created a nanotextured surface that kills bacteria while not harming mammalian cells. If additional research supports early test... 3 days
Plankton swim against the current
SCIENCE DAILY Copepods swim together in a swarm even in turbulent currents. Researchers funded by the SNSF have observed the behaviour of fish food with high-speed cameras. 3 days
Researchers suggest role for MKL1 protein in development of inflammatory bowel disease
NEWS MEDICAL Inflammatory bowel disease (IBD), including the two conditions ulcerative colitis and Crohn's disease, results in long-term inflammation of the gut and is associated with... 3 days
Climate-smart agriculture requires radical policy changes
PHYS.ORG At all levels of agricultural regulation – national, European, and international – important changes are required to be able to address the challenges of climate change. Climate-smart agriculture (CSA) is crucial, on the one hand, to... 3 days
this robotic fridge cat will remind you not to skip meals This robotic fridge cat will remind you not to skip meals
THE VERGE If you work from home, you know about the food problem. Some of us... 3 days
EU Parliament votes against banning key kebab additive
ABC NEWS The European Parliament narrowly defeated plans to ban an additive which is considered key in industrial meats for the ubiquitous doner kebab 3 days
Worries grow that climate change will quietly steal nutrients from major food crops
SCIENCE-NEWS Studies show that rice, wheat and other staples could lose proteins and minerals, putting more people at risk of hunger worldwide. 3 days
A milk protein could be used to give foods cancer-fighting, immune-boosting properties
PHYS.ORG Scientists from A*STAR have developed a system to transport a functional protein to the tissues of the digestive tract where it may confer a... 3 days
Discovery of new protein shape could impact cancer and neurodegenerative disease therapies
PHYS.ORG A Virginia Commonwealth University researcher has discovered a new conformation of a common protein group with links to cancer metastasis and neurodegenerative diseases. 3 days
Scientists discover proteins keeping stem cells in their undifferentiated state
PHYS.ORG A special cluster of proteins that helps unwind DNA during cell division plays a key role in keeping stem cells in their immature state, according to a new... 3 days
Clathrin assembly defines the onset and geometry of cortical patterning
PHYS.ORG Researchers from the Mechanobiology Institute, Singapore (MBI) at the National University of Singapore, report that endocytosis, which was previously thought to be a random process, actually occurs in... 3 days
Nanotexturing creates bacteria-killing spikes on stainless steel surfaces
PHYS.ORG By using an electrochemical etching process on a common stainless steel alloy, researchers have created a nanotextured surface that kills bacteria while not harming mammalian cells. If additional research supports early test... 3 days
Mosquito 'love potion' could stem disease spread
Sky News A protein transmitted from the male mosquito to the female during sex could prove key to preventing the spread of diseases. 3 days
Mitochondrial error-correction mechanism essential for energy production of cells
NEWS MEDICAL Mitochondria generate most of the energy cells need through a respiratory chain for which they must produce their own proteins. 3 days
Cellular self-digestion process plays role in development of autoimmune diseases
NEWS MEDICAL Autophagy allows cells to degrade and recycle their cellular components. Researchers at UZH have now demonstrated that the autophagy machinery in certain immune cells leads to the immune... 3 days
Thailand hides big numbers when it comes to its fish catches in neighbouring waters
PHYS.ORG Fish catches by Thailand's distant-water fleet fishing throughout the Indo-Pacific are almost seven times higher than what the country reports... 3 days
Mosquito sex protein could provide key to controlling disease
PHYS.ORG If you thought the sex lives of humans were complicated, consider the case of the female Aedes aegypti mosquito, bringer of Zika, dengue, and yellow fever: She mates but once,... 4 days
Mosquito sex protein could provide key to controlling disease
SCIENCE DAILY A protein transferred from male to female mosquitoes during sex influences female mating behavior -- a phenomenon that could be exploited to limit the spread of mosquito-borne illnesses like Zika... 4 days
FDA researchers find underrepresentation of adults aged 75 years and older in blood cancer clinical trials
NEWS MEDICAL In the first comprehensive analysis of clinical trial enrollment among older adults with blood cancers, researchers... 4 days
A whole-body approach to understanding chemosensory cells
SCIENCE DAILY Researchers have found a key protein (Skn-1a) acts as a master regulator for the generation of chemosensory cells in mice. As these cells are known to detect bitter or toxic substances, the study provides... 4 days
Visualizing single molecules in whole cells with a new spin
SCIENCE DAILY Scientists have adapted DNA-PAINT technology to microscopes that are widespread among cell biology laboratories, called confocal microscopes, and that are used by researchers to image whole cells and... 4 days
Team develops novel method to produce renewable acrylonitrile
PHYS.ORG A new study from the Energy Department's National Renewable Energy Laboratory (NREL) establishes a novel catalytic method to produce renewable acrylonitrile using 3-hydroxypropionic acid (3-HP), which can be biologically produced from sugars.... 4 days
Life's building blocks observed in spacelike environment
SCIENCE DAILY Where do the molecules required for life originate? It may be that small organic molecules first appeared on earth and were later combined into larger molecules, such as proteins and carbohydrates. But a second... 4 days
How honey bee gut bacteria help to digest their pollen-rich diet
SCIENCE DAILY The honey bee gut is colonized by specialized bacteria that help digest components of the floral pollen diet and produce molecules that likely promote bee health.... 4 days
Research finds a sweet spot for engineering better cellulose-degrading enzymes
PHYS.ORG Researchers from the U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) have gained new insights into how glycosylation—the natural attachment of sugars to proteins—affects a key... 4 days
How honey bee gut bacteria help to digest their pollen-rich diet
PHYS.ORG The honey bee gut is colonized by specialized bacteria that help digest components of the floral pollen diet and produce molecules that likely promote bee health.... 4 days
Deliveroo and UberEats restaurant clients face new rules
BBC Restaurants face having to seek planning permission if they heavily use food delivery apps. 4 days
Novel method produces renewable acrylonitrile
SCIENCE DAILY A novel catalytic method has been created to produce renewable acrylonitrile using 3-hydroxypropionic acid (3-HP), which can be biologically produced from sugars. This hybrid biological-catalytic process offers an alternative to the conventional petrochemical production method and achieves unprecedented... 4 days
Sweet spot for engineering better cellulose-degrading enzymes
SCIENCE DAILY New insights have been gained into how glycosylation -- the natural attachment of sugars to proteins -- affects a key cellulase enzyme. This work could be used to improve enzyme performance to better break... 4 days
Suburban ponds are a septic buffet
SCIENCE DAILY Human waste accounts for a high percentage of nutrients consumed by some animals and plants in suburban ponds, new research indicates. Researchers found that residential, suburban land use is altering the dynamics of the food chain,... 4 days
Single-dose oral vaccine could be effective tool in controlling cholera outbreaks
NEWS MEDICAL Each year there are more than three million cases of cholera worldwide, a disease transmitted through contaminated food and water that hits developing countries particularly hard. 4 days
circuit breaker live cooking gadgets and the best wireless headphones Circuit Breaker Live: Cooking gadgets and the best wireless headphones
THE VERGE Hey, you! Yes, you. Did you know we do a live gadget show on Twitter? It's... 4 days
Personality and mood swings in bacteria
PHYS.ORG Bacteria can control where they go using a signaling network of protein molecules. Scientists at AMOLF have developed a microscopy method that allows them to see how individual bacteria use this network to make decisions. They... 4 days
Searching for the CRISPR Swiss-army knife
PHYS.ORG
Plankton swim against the current
PHYS.ORG
A definitive ranking of gas station junk-food scenes in movies
THE VERGE
Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis
NEWS MEDICAL