CRISPR
New CRISPR genome “prime editing” system  NEWS MEDICAL · 8 hours
Gene editing to correct genetic faults and removing the risk of hereditary diseases may soon become reality. Researchers have come up with a new gene editing technology that could help patients with sickle cell anaemia and... more
Scientists Create New, More Powerful Technique To Edit Genes  NPR · 2 days
A new technique, dubbed 'prime editing,' appears to make it even easier to make very precise changes in DNA. It's designed to overcome the limits of the CRISPR gene editing... more
New CRISPR genome editing system offers a wide range of versatility in human cells  PHYS.ORG · 2 days
A team from the Broad Institute of MIT and Harvard has developed a new CRISPR genome-editing approach by combining two... more
New CRISPR genome editing system offers a wide range of versatility in human cells  SCIENCE DAILY · 2 days
A team has developed a new CRISPR genome-editing approach by combining two of the most important proteins in molecular biology... more
Researchers quantify Cas9-caused off-target mutagenesis in mice  SCIENCE DAILY · 4 days
Scientists are finding new ways to improve the use of the CRISPR enzyme Cas9 and reduce the chances of off-target mutations in laboratory mice, according to new results. The findings will help scientists contextualize... more
Oxford Genetics and Sphere Fluidics announce a multi-partner collaboration  NEWS MEDICAL · 1 week
Oxford Genetics and Sphere Fluidics announce a multi-partner collaboration to expedite the development of automated microfluidic systems for rapid and high-throughput gene editing in mammalian cell lines. more
CRISPR helps find difficult to detect cancer cells  NEWS MEDICAL · 1 week
Immunotherapy is one of the latest and most effective armaments against various types of cancers. Some of the immunotherapy drugs such as PD-1 inhibitor Keytruda from Merck can block certain proteins in... more
Widely Publicized Study on CRISPR Babies' Gene Mutation Now Retracted for Errors  LIVE SCIENCE · 1 week
A widely publicized study that suggested that the first gene-edited "CRISPR" babies could have shorter lifespans has been retracted due to crucial errors in... more
Study suggesting that CRISPR babies are likely to die early has been retracted  NEWS MEDICAL · 1 week
A research paper that sparked concerns about the lifespan of China's first gene-edited babies has been retracted due to technical errors. more
AAV vector integration into CRISPR-induced DNA breaks  PHYS.ORG · 1 week
To design safe clinical trials, it is crucial to better understand and predict gene editing outcomes in preclinical studies. Bence György and collaborators have shown that adeno-associated viruses (AAVs) can stably integrate into CRISPR-Cas9-induced... more
A Patient Hopes Gene-Editing Can Help With Pain Of Sickle Cell Disease  NPR · 2 weeks
She's the first patient with a genetic disorder to be treated with the powerful gene-editing technique CRISPR. The treatment has wrapped up, and now... more
CRISPR enzyme programmed to kill viruses in human cells  SCIENCE DAILY · 2 weeks
Researchers have now turned a CRISPR RNA-cutting enzyme into an antiviral that can be programmed to detect and destroy RNA-based viruses in human cells. more
CRISPR RNA-cutting enzyme programmed to destroy viruses in human cells  NEWS MEDICAL · 2 weeks
Many of the world's most common or deadly human pathogens are RNA-based viruses -- Ebola, Zika and flu, for example -- and most have no FDA-approved treatments. more
CRISPR enzyme programmed to kill viruses in human cells  PHYS.ORG · 2 weeks
Many of the world's most common or deadly human pathogens are RNA-based viruses—Ebola, Zika and flu, for example—and most have no FDA-approved treatments. A team led by researchers at the... more
After A Life Of Painful Sickle Cell Disease, A Patient Hopes Gene-Editing Can Help  NPR · 2 weeks
She's the first patient with a genetic disorder to be treated with the powerful gene-editing technique CRISPR. The treatment has... more
CRISPR-BEST prevents genome instability  PHYS.ORG · 2 weeks
Even though CRISPR technologies allow for better manipulation of genomes with many positive effects on modern drug development and the discovery of new and better antibiotics, significant problems such as genome instability and toxicity of the Cas9 protein still remain... more
CRISPR-BEST prevents genome instability  SCIENCE DAILY · 2 weeks
Scientists have developed CRISPR-BEST, a new genome editing tool for actinomycetes. It addresses the problem of genome instability caused by DNA double-stranded breaks in current CRISPR-technologies. more
Carnegie Mellon and Yale win NIH grant to advance gene editing technique  NEWS MEDICAL · 2 weeks
A research team from Carnegie Mellon University and Yale University will advance their innovative, synthetic nucleic acid-based gene editing technique under a new grant... more
Gene-edited livestock carry huge promise but major pitfalls  PHYS.ORG · 2 weeks
If American researchers have successfully employed new gene-editing techniques to develop hornless dairy cattle and piglets born castrated—a seeming boon to farmers and ranchers—they are still struggling to move these animals from... more
Researchers unlock potential to use CRISPR to alter the microbiome  SCIENCE DAILY · 3 weeks
Researchers have developed a new way to deliver the DNA-editing tool CRISPR-Cas9 into microorganisms in the lab, providing a way to efficiently launch a targeted attack on specific... more
Researchers unlock potential to use CRISPR to alter the microbiome  PHYS.ORG · 3 weeks
Researchers at Western University have developed a new way to deliver the DNA-editing tool CRISPR-Cas9 into microorganisms in the lab, providing a way to efficiently launch a targeted... more
UC Davis researchers awarded $1.5 million NIH grant for CRISPR cancer treatment  NEWS MEDICAL · 3 weeks
What if, instead of killing cancer cells or cells about to become cancerous, you could deliver a repair package and fix them? UC Davis... more
CRISPRed fruit flies mimic monarch butterfly, and could make you vomit  SCIENCE DAILY · 3 weeks
Monarch butterflies and a few other insects evolved essentially the same genetic mutations allowing them to eat toxic milkweed without getting sick. Monarch butterflies and caterpillars... more
New CRISPR-Cas9 variant has potential to increase precision during gene therapy  NEWS MEDICAL · 3 weeks
Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase precision during gene therapy in humans. more
New CRISPR-Cas9 variant may boost precision in gene editing  PHYS.ORG · 3 weeks
Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase precision during gene therapy in humans. The new variant reduced unintended changes... more
Researcher aims to make CRISPR-Cas9 system safer and more precise  NEWS MEDICAL · 4 weeks
The mere mention of gene editing and DNA altering might conjure up images of designer babies, but that is not what researcher Jin Liu has in mind. more
Researchers use immune system to attack glioblastoma  PHYS.ORG · 4 weeks
The Yale laboratory of Sidi Chen, assistant professor of genetics in the Systems Biology Institute and Yale Cancer Center, has developed advanced gene-editing and screening technology to find new targets for cancer immunotherapy. more
New discoveries map out CRISPR-Cas defense systems in bacteria  PHYS.ORG · 4 weeks
For the first time ever, researchers at the University of Copenhagen have mapped how bacterial cells trigger their defense against outside attacks. This could affect how diseases are fought in... more
New CRISPR class expands genetic engineering toolbox  SCIENCE DAILY · 4 weeks
Biomedical engineers have used a previously unexplored CRISPR technology to accurately regulate and edit target genes in human cells. With this new approach, the researchers hope to dramatically expand the CRISPR-based tools available to... more
New discoveries map out CRISPR-Cas defense systems in bacteria  SCIENCE DAILY · 4 weeks
For the first time ever, researchers have mapped how bacterial cells trigger their defense against outside attacks. This could affect how diseases are fought in the future. more
Scientists enlist tiny biomagnets for faster drug discovery  SCIENCE DAILY · 4 weeks
A new platform brings together CRISPR genome editing with magnetic cell sorting to reveal new drug targets for cancer and regenerative medicine. more
CRISPR discovery opens up new possibilities for genetic engineering  NEWS MEDICAL · 4 weeks
Scientists have successfully developed a different kind of CRISPR technology, opening up a world of possibility to future developments in the genetic engineering space more
New CRISPR class expands genetic engineering toolbox  PHYS.ORG · 4 weeks
Biomedical engineers at Duke University have used a previously unexplored CRISPR technology to accurately regulate and edit genomes in human cells. more
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