CRISPR
Biomaterials smarten up with CRISPR  SCIENCE DAILY · 4 hours
The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies that potentially can correct a defect at a single nucleotide... more
Using CRISPR to program gels with new functions  PHYS.ORG · 6 hours
The CRISPR genome-editing system is best-known for its potential to correct disease-causing mutations and add new genes into living cells. Now, a team from MIT and Harvard University has deployed CRISPR for... more
Harnessing power of CRISPR to control behavior of DNA-responsive materials  NEWS MEDICAL · 11 hours
The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies... more
Biomaterials smarten up with CRISPR  nanowerk · 22 hours
Programmable CRISPR-responsive smart materials could open the door to novel tissue engineering, bioelectronic, and diagnostic applications. more
Programmable CRISPR-responsive smart materials  Science Magazine · 23 hours
Stimuli-responsive materials activated by biological signals play an increasingly important role in biotechnology applications. We exploit the programmability of CRISPR-associated nucleases to actuate hydrogels containing DNA as a structural element or as an anchor for pendant groups. After activation by... more
Biomaterials smarten up with CRISPR  PHYS.ORG · 24 hours
The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies that potentially can correct a defect at a single nucleotide... more
Using CRISPR to program gels with new functions  MIT · 24 hours
Smart materials change properties in response to specific DNA sequences; could be used in a variety of devices. more
A new path to cancer therapy: developing simultaneous multiplexed gene editing technology  SCIENCE DAILY · 3 days
Scientists have developed a new gene editing system that could be used for anticancer immunotherapy through the simultaneous suppression of proteins that interfere with... more
California clamps down on amateur use of gene-editing technologies  NEWS MEDICAL · 3 days
California state officials have passed the first law to prohibit genetic biohacking in an effort to regulate at-home gene editing. more
A new path to cancer therapy: Developing simultaneous multiplexed gene editing technology  PHYS.ORG · 3 days
Dr. Mihue Jang and her group at the Center for Theragnosis of the Korea Institute of Science and Technology (KIST, President Byung-gwon Lee) announced... more
Researchers develop new gene editing system that could be used for anticancer immunotherapy  NEWS MEDICAL · 3 days
Dr. Mihue Jang and her group at the Center for Theragnosis of the Korea Institute of Science and Technology announced that they... more
Tweaked CRISPR in neurons gives scientists new power to probe brain diseases  SCIENCE DAILY · 1 week
Researchers describe a technique that uses a special version of CRISPR to systematically alter the activity of genes in human neurons generated from stem... more
Revolutionizing the CRISPR method  SCIENCE DAILY · 1 week
Researchers have refined the famous CRISPR-Cas method. Now, for the very first time, it is possible to modify dozens, if not hundreds, of genes in a cell simultaneously. more
Revolutionising the CRISPR method  PHYS.ORG · 1 week
Everyone's talking about CRISPR-Cas. This biotechnological method offers a relatively quick and easy way to manipulate single genes in cells, meaning they can be precisely deleted, replaced or modified. Furthermore, in recent years, researchers have also been using technologies based... more
CRISPR enters its first human clinical trials  SCIENCE-NEWS · 1 week
The gene editor will be used in lab dishes in cancer and blood disorder trials, and to directly edit a gene in human eyes in a blindness therapy test. more
A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies  Science Magazine · 2 weeks
TP53, which encodes the tumor suppressor p53, is the most frequently mutated gene in human cancer. The selective pressures shaping its mutational spectrum, dominated... more
Exploring genetic interaction manifolds constructed from rich single-cell phenotypes  Science Magazine · 2 weeks
How cellular and organismal complexity emerges from combinatorial expression of genes is a central question in biology. High-content phenotyping approaches such as Perturb-seq (single-cell RNA-seq pooled CRISPR screens) present an... more
With its CRISPR revolution, China becomes a world leader in genome editing  Science Magazine · 3 weeks
Amid controversy over gene-edited babies, government continues to pour resources into work with plants and animals more
Did CRISPR help—or harm—the first-ever gene-edited babies?  Science Magazine · 3 weeks
He Jiankui’s attempt to knock out the CCR5 gene was messy—and so are debates about potential consequences more
Targeting a blood stem cell subset shows lasting, therapeutically relevant gene editing  SCIENCE DAILY · 3 weeks
Researchers have used CRISPR-Cas9 to edit long-lived blood stem cells to reverse the clinical symptoms observed with several blood disorders, including sickle cell disease... more
Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7  Science Magazine · 3 weeks
Apoptosis is a complex multi-step process driven by caspase-dependent proteolytic cleavage cascades. Dysregulation of apoptosis promotes tumorigenesis and limits the... more
Research team redefines the footprint of viral vector gene therapy  SCIENCE DAILY · 3 weeks
Building on a track record of developing adeno-associated viral (AAV) vectors as a groundbreaking clinical tool for gene therapy and gene editing, researchers report a more sensitive method... more
New strategies for optimizing the specificity of gene editing nucleases  PHYS.ORG · 3 weeks
Sangamo Therapeutics, Inc., a genomic medicine company, announced today the publication in Nature Biotechnology of a manuscript by Jeffrey Miller, Ph.D., and colleagues at Sangamo, describing two new... more
Scientists call for modernization of EU gene-editing legislation  PHYS.ORG · 3 weeks
When using conventional methods, it usually takes relatively long to breed new plant varieties with favourable characteristics. On the other hand, precision breeding with genetic scissors such as CRISPR-Cas can significantly accelerate... more
First ever American gene-editing treatment using CRISPR for genetic disease  NEWS MEDICAL · 3 weeks
In a pathbreaking experiment, a 34-year-old mother of four from Mississippi is in the limelight for volunteering to be the subject of CRISPR-mediated gene editing in the hope... more
To feed its 1.4 billion, China bets big on genome editing of crops  Science Magazine · 4 weeks
Scientists there are forging ahead with CRISPR, even as regulations remain unclear more
Sickle Cell Patient Reveals Why She Is Volunteering For Landmark Gene-Editing Study  NPR · 4 weeks
Victoria Gray, 34, of Forest, Miss., hopes the gene-editing technique CRISPR will relieve her lifelong suffering caused by the genetic blood disorder that affects... more
New CRISPR tool enhances RNA editing  NEWS MEDICAL · 4 weeks
CRISPR-based tools helped revolutionize the ability to target genetic mutations linked to disease development. Such tools focus on using the enzymes Cas9 and Cas12 to target DNA, and Cas13 to target RNA. Now, scientists used a... more
New gene-editing study finds protective genes against Zika virus  NEWS MEDICAL · 4 weeks
Tel Aviv scientists have discovered certain genes that protect the host organism against attack by Zika virus, raising hopes of an eventual vaccine or cure for this dreaded viral disease. more
New CRISPR platform expands the reach of RNA editing to new targets  NEWS MEDICAL · 4 weeks
CRISPR-based tools have revolutionized our ability to target disease-linked genetic mutations. CRISPR technology comprises a growing family of tools that can manipulate genes and... more
First CRISPR study inside the body to start in US  ABC NEWS · 4 weeks
Patients are about to be enrolled in the first study to test gene editing inside the body to try to cure an inherited form of blindness more
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