CRISPR
Researchers working on simple, low-cost CRISPR-based diagnostic test for infectious diseases  PHYS.ORG · 1 week
Researchers in the Department of Biomedical Engineering— a shared department in the schools of Dental Medicine, Medicine, and Engineering—have been working to develop a new, low-cost,... more
Capabilities of CRISPR gene editing expanded  PHYS.ORG · 1 week
Many basic and clinical researchers are testing the potential of a simple and efficient gene editing approach to study and correct disease-causing mutations for conditions ranging from blindness to cancer, but the technology is constrained by... more
Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants  Science Magazine · 1 week
Manipulation of DNA by CRISPR-Cas enzymes requires the recognition of a protospacer adjacent motif (PAM), limiting target site recognition to a subset of sequences. To remove this constraint, we engineered variants of... more
Finding new treatments for muscular dystrophy with CRISPR-Cas9  NEWS MEDICAL · 1 week
A new study out of Boston's Children's Hospital has used the gene-editing tool CRISPR-Cas9 to explore the fatal genetic condition called facioscapulohumeral dystrophy (FSHD, one of the family of muscular dystrophies), and... more
[Research Articles] Applying genome-wide CRISPR-Cas9 screens for therapeutic discovery in facioscapulohumeral muscular dystrophy  Science Magazine · 2 weeks
The emergence of CRISPR-Cas9 gene-editing technologies and genome-wide CRISPR-Cas9 libraries enables efficient unbiased genetic screening that can accelerate the process of therapeutic... more
Humans are not the first to exploit benefits of CRISPR technique, research shows  NEWS MEDICAL · 2 weeks
In recent years, the development of CRISPR technologies and gene-editing scissors in particular have taken the world by storm. Indeed, scientists have... more
Research breakthrough: Humans are not the first to repurpose CRISPR  SCIENCE DAILY · 2 weeks
We humans are far from the first to exploit the benefits of CRISPR. Groundbreaking research has helped to redefine what CRISPR is. Researchers have discovered that primitive bacterial... more
Humans are not the first to repurpose CRISPR  PHYS.ORG · 2 weeks
In recent years, the development of CRISPR technologies and gene-editing scissors in particular have taken the world by storm. Indeed, scientists have learned how to harness these clever natural systems in the... more
Development of a CRISPR-SaCas9 system for projection- and function-specific gene editing in the rat brain  Science Magazine · 2 weeks
A genome editing technique based on the clustered regularly interspaced short palindromic repeats (CRISPR)–associated endonuclease Cas9 enables efficient... more
New kind of CRISPR technology to target RNA, including RNA viruses like coronavirus  SCIENCE DAILY · 3 weeks
Researchers have developed a new kind of CRISPR screen technology to target RNA. The team leveraged their technology for a critical analysis:... more
New kind of CRISPR technology to target RNA, including RNA viruses like coronavirus  nanowerk · 3 weeks
New genetic screening platform using CRISPR technology for targeting thousands of genes in a massively-parallel fashion; accurate and fast method of finding... more
Researchers develop new kind of CRISPR screen technology to target RNA  NEWS MEDICAL · 3 weeks
CRISPR-based genetic screens have helped scientists identify genes that are key players in sickle-cell anemia, cancer immunotherapy, lung cancer metastasis, and many other diseases. more
New kind of CRISPR technology to target RNA, including RNA viruses like coronavirus  PHYS.ORG · 3 weeks
CRISPR-based genetic screens have helped scientists identify genes that are key players in sickle-cell anemia, cancer immunotherapy, lung cancer metastasis, and many... more
Cleaving through the heart of viral infections  PHYS.ORG · 3 weeks
A novel CRISPR/Cas system that can efficiently attack and destroy several prolific plant viruses has been developed by KAUST using tobacco plants and is now being extended to rice and other crops. more
Fight for Sight funded researcher develops gene therapy approach for glaucoma  NEWS MEDICAL · 3 weeks
A Fight for Sight funded researcher from the University of Bristol has used gene editing techniques to successfully demonstrate a gene therapy for glaucoma in the... more
CRISPR-Cas system can be used to effectively target colitis pathogen  NEWS MEDICAL · 4 weeks
Research at North Carolina State University shows that the CRISPR-Cas system can be used to effectively target and eliminate specific gut bacteria, in this case Clostridioides difficile, the... more
Researchers establish new viable CRISPR-Cas12b system for plant genome engineering  PHYS.ORG · 4 weeks
In a new publication in Nature Plants, assistant professor of Plant Science at the University of Maryland Yiping Qi has established a new CRISPR genome engineering system as... more
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