A new statement by the American College of Medical Genetics and Genomics (ACMG), published in the journal Genetics in Medicine, discusses the place of... more
Cancer of the throat and mouth (oropharyngeal cancers, OPC) are common, and are increasing in incidence especially among younger people. However, these are difficult to diagnose... more
Results from NRG Oncology's BR005 study show that breast-conserving treatment without surgery cannot be recommended, based on the study criteria of clinical complete response, radiological complete response (rCR)/near... more
While trying to develop a comparatively easy, inexpensive way to give physicians and their patients with bladder cancer a better idea of likely outcome and best treatment options,... more
Pooled analysis of three phase 1 and 2 clinical trials published online ahead of print in the journal Lancet Oncology show that the drug entrectinib is... more
Precision medicine with targeted therapies has led to improved treatment options and patient outcomes. These approaches were developed by studying tumors grown in laboratories... more
Mitochondria, tiny structures present in most cells, are known for their energy-generating machinery. Now, researchers have discovered a new function of mitochondria: they set off molecular... more
Mitochondria, tiny structures present in most cells, are known for their energy-generating machinery. Now, Salk researchers have discovered a new function of mitochondria: they set off... more
Researchers have taken a critical step toward developing a non-invasive nuclear medicine technique that can predict the effectiveness of therapy for cancerous tumors, allowing... more
If you want to predict which breast cancer patients will most likely stop taking aromatase inhibitors, check out their own responses to the health questions patients commonly answer in cancer clinical trials, according to... more
Indiana University School of Medicine researchers have discovered how to predict whether triple negative breast cancer will recur, and which women are likely to... more
While trying to develop a comparatively easy, inexpensive way to give physicians and their patients with bladder cancer a better idea of likely outcome and best treatment options, scientists found... more
General control nonderepressible 2 (GCN2) is an environmental sensor controlling transcription and translation in response to nutrient availability. Although GCN2 is a putative therapeutic... more
Exposure to electromagnetic radiation (EMR) from the sun and from artificial lighting systems represents a modifiable risk factor for a broad range of health conditions including skin cancer,... more
Women who use certain types of hormones after menopause may still have an increased risk of developing breast cancer nearly two decades after they stop taking the pills more
Women who use certain types of hormones after menopause may still have an increased risk of developing breast cancer nearly two decades after they stop taking the pills more
A retrospective study of nearly 9800 women with breast cancer who participated in randomized clinical trials was presented today at the 2019 San Antonio Breast Cancer... more
According to a statement on behalf of the American College of Medical Genetics and Genomics (ACMG) published Dec. 13 in the organization's official journal, Genetics in Medicine, there... more
Caution is advised in interpreting the findings of the recent JAMA Internal Medicine publication1 on radioactive iodine treatment for hyperthyroid patients and cancer mortality. more
Targeted, highly effective cancer treatments often produce debilitating side effects. This is the case with one commonly used therapy which works by blocking the epidermal growth factor receptor,... more
A team of scientists from Peter the Great St.Petersburg Polytechnic University together with their colleagues developed a method of targeted drug delivery to cancer cells. more
Stringing the lights, storming the malls and all those parties! Imagine facing these holiday demands while you're tired, sick, sad and worried: for people... more
Researchers from the Baylor College of Medicine and Harvard Medical School have found a novel mechanism to explain the resistance of certain breast cancers that spread... more
High-fat diets and obesity have been shown to increase the risk of breast cancer and worsen outcomes and prognosis of breast cancer patients. A team of... more
Fewer than 10% of dermatologists practice in rural areas, according to the Journal of the American Academy of Dermatology. That means primary care physicians (PCPs) are often relied... more
Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the... more
One of most potent drugs for treatment of glioblastoma, the most deadly type of brain tumor, can't be used in patients because of two problems. First,... more
Autoimmune disorders such as rheumatoid arthritis, psoriasis, and Crohn's disease plague tens of millions of Americans and are the result of the body's immune system, whose... more
An international team of scientists have made drug-like molecules inspired by a chemical found in a tropical flower, that they hope could in the future help to treat... more
What if scientists could create more effective drugs to treat cancers and other diseases by better targeting specific sites on proteins in the body? more
Patients with well-supported immune cells in their tumors are more likely to control their cancers' growth for a longer time, an observation that could guide treatment decisions after surgery for kidney cancer.... more
The new book "Football as Medicine - Prescribing Football for Global Health Promotion" collates 15 years of research when describing the effects of football training on cardiovascular, metabolic... more
Vaccinia viruses serve as a vaccine against human smallpox and as the basis of new cancer therapies. Two studies now provide fascinating insights into their unusual propagation strategy at the atomic level. more
A computational study by chemists showed the dynamics of tumor formation don't necessarily correlate with clinical data on lifetime cancer risks. It suggests biomarkers may someday be able to help predict when mutations in cells will... more
Australian researchers are making major inroads into finding the cause of heart disease, Alzheimer's, cancer, diabetes and other diseases after discovering a further 148 proteins affected... more
Clinical Research Pathways is partnering with WellStar Health System to increase diversity in oncology research to help ensure that new cancer medicines... more
The Queen Mary University of London professor leading an international breast cancer study says anastrozole - rather than tamoxifen - should be the preventive drug-of-choice for... more
Flinders researchers have made major inroads into finding the cause of heart disease, Alzheimer's, cancer, diabetes and other diseases after discovering a further 148 proteins affected by oxidative stress in the human body. more
Looking to gain a deeper understanding of cancer, a team led by researchers at Baylor College of Medicine conducted an extensive computational analysis of the similarities and differences... more
St. Jude Children's Research Hospital scientists have identified a new therapeutic strategy that enhanced cancer immunotherapy, slowed tumor growth and extended the lives of mice with cancer. The research appears today in... more
Artificial intelligence (AI) is being tested in clinics around the world, but is it a realistic ambition to apply sophisticated algorithms to cancer care? more
In the last decade, scientists discovered that blocking a key regulator of the immune system helped unleash the body's natural defenses against several forms... more
Researchers say a new method to analyse data from individual human cells could be a step-change for diagnosing some of the most devastating diseases, including cancer and autoimmune disease. more
What if scientists could create more effective drugs to treat cancers and other diseases by better targeting specific sites on proteins in the body? more
The National Comprehensive Cancer Network (NCCN) hosted an annual NCCN Patient Advocacy Summit: Delivering Value for Patients across the Oncology Ecosystem in... more
A new preclinical study on triple negative breast cancer (TNBC) reports that an experimental polo-like kinase 1 (PLK1) inhibitor shrank tumor four times more powerfully when... more
There have been conflicting reports on health benefits and harm caused by drinking alcohol. A new study from Japanese researchers has proven that taking one drink a day for a... more
A new study reveals the mechanism that helps pancreatic cancer cells avoid starvation within dense tumors by hijacking a process that pulls nutrients in from their surroundings. more
A new study reveals the mechanism that helps pancreatic cancer cells avoid starvation within dense tumors by hijacking a process that pulls nutrients in from their surroundings. more
An international team of scientists led by the University of Bath have made drug-like molecules inspired by a chemical found in a tropical flower,... more
Transcription factors (TFs) are spatially and temporally regulated during gut organ specification. Although accumulating evidence shows aberrant reactivation of developmental programs in cancer, little... more
Non-Hodgkin lymphoma refers to a group of cancers that start in the white blood cells. This article looks at their types, symptoms, diagnosis, and treatment. more
Congress has reached a deal on a spending bill that would require the military to stop using firefighting foam containing toxic chemicals linked to cancer, but... more
High Intensity Focused Ultrasound (HIFU) treatment is a non-invasive method that removes unhealthy tissues and tumors by delivering high intensity ultrasound waves from outside of the body to... more
What if scientists could create more effective drugs to treat cancers and other diseases by better targeting specific sites on proteins in the body? more
Neuroblastoma can grow and spread in the body very aggressively, making it very difficult to treat. New research has shed important light on the factors at... more
Researchers from The University of Texas MD Anderson Cancer Center today reported study results showing the addition of tucatinib to capecitabine (Xeloda) and trastuzumab (Herceptin) significantly improved progression-free... more
Doctors are reporting unusually good results from tests of two experimental drugs in women with an aggressive form of breast cancer that had spread widely and resisted treatment more
Scientists recently announced the discovery of a novel antibiotic produced by bacteria living inside a nematode (roundworm). Although this molecule needs further... more
IONTAS Limited, a leader in the discovery and optimization of fully human antibodies, has been informed that International Biotechnology Center Generium, a... more
Federal regulations may keep lung cancer patients out of clinical trials simply because these patients are on medications that might affect the electrical system of the heart. Drilling... more
Gastric intestinal metaplasia (GIM), which is linked to non-cardia gastric cancer, is often detected during routine endoscopy, leading to questions about how patient care should be... more
Results from a study conducted by St. Jude Children's Research Hospital and the Munich Leukemia Laboratory were presented today as a late-breaking abstract at the American... more
Non-alcoholic fatty liver diseases (NAFLD) and alcohol-related diseases (ALD) are currently the leading cause of chronic disease, cancer and mortality associated with this organ in developed countries. more
New findings from a clinical trial show that treatment with the immunotherapy drug blinatumomab is superior to standard chemotherapy for children and young adults... more
Scientists from Utrecht University have applied advanced microscopy to visualize the activity of the widely used drug Taxol. Taxol is often used... more
While the assessment of proton therapy in breast cancer treatment continues through clinical trials, data relating to early toxicity and cosmetic outcomes for this... more
Deep DNA sequencing analysis conducted by Rutgers Cancer Institute of New Jersey investigators examining genomic differences within tumors for prediction of disease... more
The antibiotic vancomycin alters the gut microbiome in a way that can help prime the immune system to more effectively attack tumor cells after... more
As U.S. Latinos face a staggering 142% projected rise in cancer cases by 2030, UT Health San Antonio leaders gathered international cancer experts to publish a new book... more
A one-year follow-up study led by The University of Texas MD Anderson Cancer Center revealed a majority of patients with mantle cell lymphoma resistant to prior... more
A new paper in Family Practice, published by Oxford University Press, found that the widespread use of statins and cancer screening technology may have... more
UT Southwestern researchers have developed a software tool that uses artificial intelligence to recognize cancer cells from digital pathology images - giving... more
A multi-institutional, Phase II study led by The University of Texas MD Anderson Cancer Center showed that pairing standard chemotherapy azacitidine (AZA) with a drug called... more
Mount Sinai researchers have designed an innovative experimental therapy that may be able to stop the growth of triple-negative breast cancer, the deadliest type of breast cancer, which... more
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