Cancer
Research provides guidance for treating pancreatic cancer patients during COVID-19 pandemic  NEWS MEDICAL · 2 hours
The novel coronavirus (COVID-19) pandemic not only affects patients who have the virus, but strikes the entire healthcare system including the care for patients with cancer. more
New understanding of RNA movements can be used to treat cancer  SCIENCE DAILY · 4 hours
New research shows that an RNA molecule involved in preventing tumor formation can change its structure and thereby control protein production in the cell. The finding... more
Researchers develop promising immunotherapy treatment for glioblastoma  NEWS MEDICAL · 10 hours
Researchers of McMaster University and the University of Toronto have developed a promising immunotherapy treatment for a deadly form of adult brain cancer called glioblastoma. more
Surgeons study guidelines for treating cancer patients during pandemic  SCIENCE DAILY · 10 hours
New research provides guidance on clinical decision-making in regards to treating pancreatic cancer patients during the COVID-19 pandemic. more
Novel immunotherapy targeting myeloid immune cells reduces tumor growth  NEWS MEDICAL · 10 hours
Checkpoint inhibitors, a type of immunotherapy, that target myeloid immune cells and slow tumor growth were discovered by a team from the Perelman School of Medicine at the University of... more
Phenotype stability under dynamic brain-tumor environment stimuli maps glioblastoma progression in patients  Science Magazine · 10 hours
Although tumor invasiveness is known to drive glioblastoma (GBM) recurrence, current approaches to treatment assume a fairly simple GBM phenotype transition map. We provide... more
[Research Articles] Blocking immunosuppressive neutrophils deters pY696-EZH2-driven brain metastases  Science Magazine · 10 hours
The functions of immune cells in brain metastases are unclear because the brain has traditionally been considered "immune privileged." However, we found that a subgroup of immunosuppressive neutrophils is recruited... more
Ivy Center opens new clinical trial to evaluate experimental drug cocktail for glioblastoma  NEWS MEDICAL · 11 hours
The Ivy Brain Tumor Center at Barrow Neurological Institute announced that patient recruitment has opened for a new Phase 0 clinical trial... more
Findings provide new insights into future cancer treatment  NEWS MEDICAL · 12 hours
An early age of pregnancy (25 years and younger) is known to reduce the overall risk of breast cancer by over 30%. CSHL Assistant Professor Camila dos Santos spent several years teasing... more
New understanding of RNA movements can be used to treat cancer  PHYS.ORG · 13 hours
Research from Karolinska Institutet published today in Nature shows that an RNA molecule involved in preventing tumour formation can change its structure and thereby control protein... more
A promising method for treating triple-negative breast cancer  NEWS MEDICAL · 13 hours
Researchers at the University of Queensland may have found a way to improve treatment of triple-negative breast cancer. more
A new approach to predict the evolutionary mechanisms of melanoma  NEWS MEDICAL · 13 hours
Melanoma is a malignant tumour resulting from the transformation of melanocytes, the cells in the skin that undertake to synthesise melanin, a complex polymer which protects us from... more
Researchers investigate the early development of ovarian cancer  NEWS MEDICAL · 14 hours
Researchers from the group of Hans Clevers at the Hubrecht Institute have modeled the development and progression of high-grade serous ovarian cancer in mini-versions of the female reproductive organs of the mouse. more
Stand Up To Cancer hails FDA approval of new treatment option for aggressive prostate cancer  NEWS MEDICAL · 23 hours
A recent FDA approval supported by Stand Up To Cancer research provides a new treatment option for patients... more
Lymph node and distant metastases develop through different evolutionary mechanisms, study shows  NEWS MEDICAL · 1 day
The evolutionary processes underlying metastasis-the development of secondary malignant growths away from the primary tumor site-in human patients are still incompletely understood. more
Study uncovers how protein inhibits the development of tumors in mice  NEWS MEDICAL · 1 day
Proteins are found throughout our cells and regulate a lot of biological processes that are important forour survival. more
UZH researchers develop new X-ray contrast agent for high-resolution vascular imaging  NEWS MEDICAL · 1 day
Various diseases in humans and animals - such as tumors, strokes or chronic kidney disease - damage the blood vessels. Capillaries, the smallest blood vessels in... more
New technique offers high-resolution 3D view inside tumors  NEWS MEDICAL · 1 day
Malignant tumors consume nutrients and oxygen faster than healthy cells. To do so, they recruit blood vessels in their environment. Depending on tumor type and genetic profile, there are differences on how... more
Antimalarial drug shows promise as potential therapy for aggressive brain cancer  NEWS MEDICAL · 1 day
Glioblastoma multiforme is an aggressive form of cancer in the brain that is typically fatal. But new findings by VCU Massey Cancer Center and VCU Institute... more
Dana-Farber nurse-scientists receive more than $1.3 million for two research projects  NEWS MEDICAL · 1 day
Nurse-scientists from the Phyllis F. Cantor Center for Research in Nursing and Patient Care Services at Dana-Farber Cancer Institute received more than $1.3 million dollars in... more
How a protein can inhibit cancer development in mice  SCIENCE DAILY · 1 day
In a new study, researchers have discovered how the protein PP2A can inhibit tumor growth in mice. The protein turns off an enzyme that stimulates cell growth, thus inhibiting the... more
Finding unique drug structures with artificial intelligence and chemistry  PHYS.ORG · 1 day
In the search for new medicines against diseases such as cancer, a Leiden team has developed a new workflow. This approach combines artificial intelligence (AI) with molecular modelling and is... more
Researchers identify genetic mechanisms that produce radioresistance in cancer cells  NEWS MEDICAL · 2 days
Cancer stem cells are a cell type that was previously little known. They are resistant to irradiation and prevent the effective treatment of many types of cancer. A... more
Free app helps assess the risk of delaying cancer care during COVID-19  NEWS MEDICAL · 2 days
As the COVID-19 pandemic has overwhelmed healthcare systems across the country, doctors have postponed surgery and other treatments for thousands of patients with cancer. more
Advanced MRI picks out even small tumors from normal tissue  NEWS MEDICAL · 2 days
Researchers at the University of California, Davis offers a significant advance in using magnetic resonance imaging to pick out even very small tumors from normal tissue. more
Inherited genetic variations can alter progression of melanoma, indicates study  NEWS MEDICAL · 2 days
Sometimes cancer stays put, but often it metastasizes, spreading to new locations in the body. It has long been suspected that genetic mutations arising inside tumor cells drive... more
New double-contrast technique picks up small tumors on MRI  SCIENCE DAILY · 2 days
Early detection of tumors is extremely important in treating cancer. A new technique offers a significant advance in using magnetic resonance imaging to pick out even very small tumors from... more
Scientists discover how an obscure protein promotes breast cancer progression  NEWS MEDICAL · 2 days
South Australian scientists have made a critical breakthrough, discovering how an obscure protein causes breast cancer to develop and grow more quickly. more
New therapeutic approach for aggressive breast cancer  NEWS MEDICAL · 2 days
This type of TNBC tumor does not express any of the receptors involved in most breast cancers (estrogen, progesterone and HER2), so the most common treatments, such as the hormone therapy, are not viable... more
Study reveals first evidence inherited genetics can drive cancer's spread  SCIENCE DAILY · 2 days
Scientists have long struggled to understand what drives a tumor to seed itself elsewhere in the body. New research implicates own pre-existing genetics. more
New double-contrast technique picks up small tumors on MRI  nanowerk · 3 days
A new technique offers a significant advance in using magnetic resonance imaging to pick out even very small tumors from normal tissue. more
New double-contrast technique picks up small tumors on MRI  PHYS.ORG · 3 days
Early detection of tumors is extremely important in treating cancer. A new technique developed by researchers at the University of California, Davis offers a significant advance in using magnetic resonance... more
A 'switch' that turns autoimmunity drugs into powerful anti-cancer treatments  SCIENCE DAILY · 5 days
Scientists have discovered a way to transform antibody drugs previously developed to treat autoimmunity into antibodies with powerful anti-cancer activity through a simple molecular 'switch'. more
Self-healing microcapsules synergetically modulate immunization microenvironments for potent cancer vaccination  Science Magazine · 5 days
Therapeutic cancer vaccines that harness the immune system to reject cancer cells have shown great promise for cancer treatment. Although a wave of efforts have spurred to improve... more
Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy  Science Magazine · 5 days
Interpreting how multicellular interactions in the tumor affect resistance pathways to BRAF and MEK1/2 MAPK inhibitors (MAPKi) remains a challenge. To investigate this, we profiled global... more
Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation  Science Magazine · 5 days
Inflammation is an essential part of immunity against pathogens and tumors but can promote disease if not tightly regulated. Self and non-self-nucleic acids can trigger inflammation, through recognition by the... more
Scientists identify key cell signaling pathway that drives muscle loss  NEWS MEDICAL · 6 days
Researchers at the University of Nebraska Medical Center have identified a key cell signaling pathway that drives the devastating muscle loss, or cachexia, suffered by many cancer patients. more
Breast cancer survivors underutilize supportive care to relieve cancer-related fatigue  NEWS MEDICAL · 6 days
Cancer-related fatigue is a prevalent and potentially persistent issue among breast cancer survivors, which can prevent them from returning to their previous life well after treatment ends and... more
Cockle shells picked to treat dog cancer  PHYS.ORG · 6 days
The calcium mineral from which many shellfish, such as cockles, make their shells can be used to form nanoparticles. These nanoparticles can then be "loaded" with small drug molecules, such as anticancer drugs. more
New follow-up care models could benefit thousands of cancer survivors  NEWS MEDICAL · 6 days
Thousands of cancer survivors could benefit from a new model of shared follow-up care delivered by specialist cancer care nurses, GPs, and cancer specialists incorporating telehealth sessions being... more
Recommendations for treating bladder cancer during COVID-19 pandemic  NEWS MEDICAL · 6 days
Bladder cancer is associated with significant illness and mortality, particularly if treatment is delayed. more
Researchers to use digital technologies to help tackle chronic disease  NEWS MEDICAL · 6 days
Sedentary behaviours, poor sleep and questionable food choices are major contributors of chronic disease, including diabetes, anxiety, heart disease and many cancers. more
Parents lack understanding of teens' preferences for best time to talk about end-of-life decisions  NEWS MEDICAL · 6 days
The findings of a survey of adolescent cancer patients and their families at four tertiary care U.S. pediatric hospitals showed... more
Simple molecular 'switch' transforms autoimmunity drugs into powerful anti-cancer treatments  NEWS MEDICAL · 6 days
Scientists from the Antibody and Vaccine group at the University of Southampton have discovered a way to transform antibody drugs previously developed to treat autoimmunity into antibodies with... more
Distribution of human tumor mutations more similar to that of chimpanzees, gorillas  NEWS MEDICAL · 6 days
A new study by researchers from the Institute of Evolutionary Biology (IBE), a joint centre of UPF and the Spanish National Research Council (CSIC),... more
Scientists create a detailed map of how carcinogens trigger breast cancer development  NEWS MEDICAL · 6 days
In the most comprehensive review to date of how breast cancer develops, scientists have created a detailed map that describes the many ways in... more
Just a little physical activity can have big impact for women with high-risk breast cancer  NEWS MEDICAL · 6 days
Results of a comprehensive analysis of exercise and its protective role for high-risk breast cancer patients show that... more
Cell-culture based in vitro test systems for antitumor drug screening  NEWS MEDICAL · 6 days
As we know, a malignant tumor is a complex system of mutated cells which constantly interacts with and involves healthy cells in the body. more
Researchers receive $5.75 million to study link between obesity, inflammation and pancreatic cancer  NEWS MEDICAL · 6 days
A team of researchers from the UCLA Jonsson Comprehensive Cancer Center and peer institutions has been awarded a $5.75 million grant from... more
The genome of chimpanzees and gorillas could help to better understand human tumors  PHYS.ORG · 6 days
A new study by researchers from the Institute of Evolutionary Biology (IBE), a joint centre of UPF and the Spanish National Research... more
Scientists use new model to develop cancer stem cells  NEWS MEDICAL · 7 days
Liver cancer is one of the deadliest cancers. It is insidious and does not present symptoms until it has progressed considerably, at which point, treatment options are limited and chances... more
Comprehensive review of clioquinol drug gives valuable insights  NEWS MEDICAL · 7 days
CQ is an old drug that was commonly used to treat fungal/protozoal infections of the gastrointestinal tract. Patients in Japan taking it developed subacute myelo-optic neuropathy which resulted in CQ being discontinued... more
Plant virus-like particles as vehicles for therapeutic antibodies  PHYS.ORG · 7 days
Monoclonal antibodies are those that originate from identical immune cells having a common origin. They are highly effective, non-toxic and can specifically target diseased cells, and are therefore used in immunotherapy to... more
Research looks at COVID-19 in cancer patients  NEWS MEDICAL · 7 days
As the world grapples with the COVID-19 pandemic, new questions arise as to the risk posed by the virus to different patient populations, including the elderly and those with underlying disease. A new study... more
Molecular testing rates in most countries less than 50%, IASLC survey finds  NEWS MEDICAL · 1 week
Access to targeted therapies for lung cancer depends on accurate identification of patients' biomarkers through molecular testing, but survey results published today in the... more
Durvalumab plus chemotherapy improved overall survival rate for mesothelioma patients  NEWS MEDICAL · 1 week
PrECOG, LLC is reporting clinical efficacy and biomarker analyses from its single-arm phase two study PrE0505 for the initial treatment of patients with malignant pleural mesothelioma. more
New technique reveals potentially treatable mutations in subset of prostate cancer patients  NEWS MEDICAL · 1 week
Prostate cancer patients who do not respond well to PSMA-targeted therapy often have potentially treatable mutations in their DNA damage-repair genes, according to research... more
Nanobowls serve up chemotherapy drugs to cancer cells  SCIENCE DAILY · 1 week
For decades, scientists have explored the use of liposomes -- hollow spheres made of lipid bilayers -- to deliver chemotherapy drugs to tumor cells. But drugs can sometimes leak out of liposomes... more
Dana-Farber launches clinical test of blood cancer drug in COVID-19 patients  NEWS MEDICAL · 1 week
Scientists at Dana-Farber Cancer Institute have launched a clinical test of a blood cancer drug in patients infected with the COVID-19 virus. T more
'Senolytic' therapy blunts liver tumor progression in animal models  NEWS MEDICAL · 1 week
"Senotherapy," a treatment that uses small molecule drugs to target "senescent" cells, or those cells that no longer undergo cell division, blunts liver tumor progression in animal models according to... more
Engineered algae: A novel oxygen-generating system for effective treatment of hypoxic cancer  Science Magazine · 1 week
Microalgae, a naturally present unicellular microorganism, can undergo light photosynthesis and have been used in biofuels, nutrition, etc. Here, we report that engineered live... more
Remote modulation of lncRNA GCLET by risk variant at 16p13 underlying genetic susceptibility to gastric cancer  Science Magazine · 1 week
The biological effects of susceptibility loci are rarely reported in gastric tumorigenesis. We conducted a large-scale... more
Chimeric antigen receptor signaling: Functional consequences and design implications  Science Magazine · 1 week
Chimeric antigen receptor (CAR) T cell therapy has transformed the care of refractory B cell malignancies and holds tremendous promise for many aggressive tumors. Despite overwhelming scientific, clinical, and public... more
Chemiluminescence resonance energy transfer-based nanoparticles for quantum yield-enhanced cancer phototheranostics  Science Magazine · 1 week
Chemiluminescence (CL) has recently gained attention for CL resonance energy transfer (CRET)–mediated photodynamic therapy of cancer. However, the short duration of the CL signal and low quantum yield... more
Dose-dependent functions of SWI/SNF BAF in permitting and inhibiting cell proliferation in vivo  Science Magazine · 1 week
SWI/SNF (switch/sucrose nonfermenting) complexes regulate transcription through chromatin remodeling and opposing gene silencing by Polycomb group (PcG) proteins. Genes encoding SWI/SNF components... more
New test strip could provide accurate point-of-care diagnostics for cancer, COVID-19  NEWS MEDICAL · 1 week
A new synthetic paper for finger-prick blood tests could provide accurate point-of-care diagnostics for cancer, COVID-19, and other serious diseases. more
'Anti-ageing' protein shown to slow cell growth is key in longevity – new research  PHYS.ORG · 1 week
Humans are living longer than ever before. But alongside these increases in life expectancy are an increase in the occurrence of age-related... more
Radiation oncology clinics report fewer patients despite improved safety measures  NEWS MEDICAL · 1 week
Despite facing challenges such as limited access to personal protective equipment (PPE) following the COVID-19 outbreak, radiation oncology clinics quickly implemented safety and process enhancements that allowed them... more
Researchers report a new way to stabilize liposomes  NEWS MEDICAL · 1 week
For decades, scientists have explored the use of liposomes –– hollow spheres made of lipid bilayers –– to deliver chemotherapy drugs to tumor cells. more
New test strip preserves clues that blood tests often miss  PHYS.ORG · 1 week
A new synthetic paper for finger prick blood tests could provide accurate point-of-care diagnostics for cancer, COVID-19 and other serious diseases. Researchers at KTH Royal Institute of Technology... more
Nanobowls serve up chemotherapy drugs to cancer cells  nanowerk · 1 week
Researchers report a way to stabilize liposomes by embedding a stiff nanobowl in their inner cavity. more
Nanobowls serve up chemotherapy drugs to cancer cells  PHYS.ORG · 1 week
For decades, scientists have explored the use of liposomes—hollow spheres made of lipid bilayers—to deliver chemotherapy drugs to tumor cells. But drugs can sometimes leak out of liposomes before they reach their... more
USC-Olympus partnership in multiscale bioimaging furthers precision medicine  NEWS MEDICAL · 1 week
As a global leader in endoscopy and life science solutions, Olympus has long been committed to promoting awareness of cancer screening, prevention and testing. In this spirit, the company recently forged a... more
Study examines 5-aminolevulinic acid induced fluorescence in surgery of brain metastases  NEWS MEDICAL · 1 week
Two-thirds of brain metastases give off fluorescence following administration of 5-aminolevulinic acid, which could potentially assist surgeons in identifying such tumors. more
New drug treatment can reduce risk of death from COVID-19 infection  NEWS MEDICAL · 1 week
Researchers in the Ludwig Center at the Johns Hopkins Kimmel Cancer Center report they have identified a drug treatment that could--if given early enough--potentially reduce the... more
Study could help identify more targeted treatments for ovarian cancer  NEWS MEDICAL · 1 week
The rogue cellular engine that drives a majority of ovarian cancers remains frustratingly difficult to disable. A new study comparing cancerous tissue with normal fallopian tube samples advances... more
Location, location, location: The cell membrane facilitates RAS protein interactions  SCIENCE DAILY · 1 week
Many cancer medications fail to effectively target the most commonly mutated cancer genes in humans, called RAS. Now, scientists have uncovered details into how normal RAS interacts with... more
Understanding why pancreatic ductal adenocarcinoma is so aggressive  NEWS MEDICAL · 1 week
Pancreatic ductal adenocarcinoma (PDA) is a deadly cancer, killing patients within a year. CSHL Professor Christopher Vakoc and his former postdoc Timothy Somerville discovered how pancreatic cells lose their identity, acquire a... more
Cancer researchers locate drivers of tumor resistance  SCIENCE DAILY · 1 week
How do tumors change their behavior and resist anticancer therapies? Cancer biologists have documented genetic signals that promote the conversion of cancer cells into those that resist therapy. more
Genome study links DNA changes to the risks of specific breast cancer subtypes  SCIENCE DAILY · 1 week
An analysis of genetic studies covering 266,000 women has revealed 32 new sites on the human genome where variations in DNA appear... more
Phase IIB clinical trial initiated for treating hepatitis B-associated liver cancer  NEWS MEDICAL · 1 week
The first patients have been dosed in a multi-regional Phase IIB randomized, placebo-controlled clinical trial for the treatment of hepatitis B-associated liver cancer. more
SWOG scientists to deliver online presentations at ASCO20 Virtual Scientific Program  NEWS MEDICAL · 1 week
Researchers from SWOG, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health, will make 31 presentations... more
MicroRNA: The 'junk' genetic material with huge potential to fight cancer and dementia  PHYS.ORG · 1 week
Only 1.1% of the nearly 3 billion molecules that make up our genome actually provide genetic instructions. When scientists first worked out... more
Study: Personalized ovarian cancer risk prediction reduces worries among a majority of women  NEWS MEDICAL · 1 week
Offering personalised ovarian cancer risk prediction to women shows that 98 per cent of participants felt less worried after finding out their... more
Climate change threatens progress in cancer control  SCIENCE DAILY · 1 week
Climate change threatens prospects for further progress in cancer prevention and control, increasing exposure to cancer risk factors and impacting access to cancer care, according to a new commentary. more
A new epigenetic editing tool is developed to activate silenced genes  PHYS.ORG · 1 week
Although all cells in an organism have the same genetic information, not all perform the same function, being as not all of them have the same... more
Location, location, location: The cell membrane facilitates RAS protein interactions  PHYS.ORG · 1 week
Many cancer medications fail to effectively target the most commonly mutated cancer genes in humans, called RAS. Now, Salk Professor Geoffrey Wahl and a team of scientists have... more
Multi-institutional clinical trial sheds new light on non-responsive tumors  NEWS MEDICAL · 1 week
Over the last decade, enzalutamide and similar drugs have led to significant tumor control and increased survival time for men who have metastatic prostate cancer that continues to grow despite... more
Study shows how normal RAS interacts with mutated RAS in living cells  NEWS MEDICAL · 1 week
Many cancer medications fail to effectively target the most commonly mutated cancer genes in humans, called RAS. more
Innovent Biologics and MD Anderson to develop sintilimab injection for rare cancers  NEWS MEDICAL · 1 week
The University of Texas MD Anderson Cancer Center and Innovent Biologics, Inc. today announced a strategic collaboration agreement to co-develop TYVYT® (sintilimab injection), Innovent's... more
Study shows how cancer protein changes may accelerate tumorigenesis and metastasis  NEWS MEDICAL · 1 week
Understanding the genetic mutations and protein changes that take place in the progression of cancer is key to its treatment. Mutations in the gene TP53 and... more
Researchers identify determining factor in luminal cancer cells  NEWS MEDICAL · 1 week
The Translational Control of Cell Cycle and Differentiation Lab at IRB Barcelona, led by ICREA researcher Raúl Méndez, has published a study in the journal Science Advances that has identified a key... more
New analysis links DNA variations to risks of specific breast cancer subtypes  NEWS MEDICAL · 1 week
An analysis of genetic studies covering 266,000 women has revealed 32 new sites on the human genome where variations in DNA appear to alter... more
Novel microRNA biomarker could help detect lymph node metastases in pancreatic cancer patients  NEWS MEDICAL · 1 week
For years, surgeons have operated on pancreatic cancer patients to remove what they thought was a localized tumor only to discover that... more
A new tool to study and map the intricacies of intercellular signaling  NEWS MEDICAL · 1 week
How do cells move? Why do they move? Why do some cancer cells move slowly while others move quickly, causing a cancerous tumor to... more
Novel LAT1 inhibitor could be useful in the treatment of various cancers  NEWS MEDICAL · 1 week
Researchers at the University of Eastern Finland have developed a new and promising drug compound for the treatment of cancer that inhibits natural amino... more
Cancer biologists identify important drivers of tumor resistance  NEWS MEDICAL · 1 week
Cancer biologists at the Mays Cancer Center, home to UT Health San Antonio MD Anderson, have identified important drivers that enable tumors to change their behavior and evade anticancer therapies. more
A new tool to map the flow of info within living cells  SCIENCE DAILY · 1 week
Researchers created a way to study the intricacies of intercellular signaling -- when, where, and how tiny parts of cells communicate -- to make... more
MORE SCIENCE VIDEO
USC-Olympus partnership in multiscale bioimaging furthers precision medicine
NEWS MEDICAL
Filtering out toxic chromium from water
PHYS.ORG
FRESH SCIENCE