In an effort to further individualize therapy and avoid over-treating patients, researchers at the Johns Hopkins Kimmel Cancer Center report a new study using PET scans... more
In an effort to further individualize therapy and avoid over-treating patients, researchers report a new study using PET scans has identified a biomarker that... more
There is currently not enough evidence related to the effects of noncaloric sweeteners on appetite, short‑term intake, and risk of suffering from cancer or diabetes, as... more
The detailed findings in a new paper could lead to more precise, effective methods of treating and diagnosing a variety of diseases, including cancers. more
A new study suggests that high-fat diets fuel colorectal cancer growth by upsetting the balance of bile acids in the intestine and triggering a hormonal signal that lets potentially cancerous... more
Scientists have long sought to develop drug therapies that can more precisely diagnose, target and effectively treat life-threatening illness such as cancer, cardiovascular and autoimmune diseases. One promising approach is the design... more
Consumption of allium vegetables—which include garlic, leeks, and onions—was linked with a reduced risk of in colorectal cancer in a study of men and women in China. more
Previous studies have shown that estrogens and estrogen-like compounds reduce multiple sclerosis-like inflammation and disability in mice. At first glance these treatments appear promising, but they carry a host of... more
Researchers have published the first clinical study investigating the use of the direct oral anticoagulant, rivaroxaban, to prevent blood clots in patients with cancer at high-risk.... more
Spouses can help breast cancer patients with coping by positively reframing the cancer experience and other negative experiences. In general, positive reframing -- finding the silver lining -- was associated with less... more
An immunotherapeutic antibody therapy re-educates macrophages to activate passivated cytotoxic T cells to kill cancer. The antibody therapy prevented the growth of tumours in several mouse... more
Consumption of allium vegetables -- which include garlic, leeks, and onions -- was linked with a reduced risk of in colorectal cancer in a study of men and women in... more
Zirconium-89 is a radionuclide that's just right for cancer tumor imaging. When the isotope is combined with a tumor-seeking molecule, it lasts long enough in the body to find the tumor and to be imaged. Researchers developed a less labor... more
Owlstone Medical Ltd., a global diagnostics company developing a breathalyzer for applications in early disease detection and precision medicine, and... more
Scaling up the human papillomavirus (HPV) vaccine could eradicate cervical cancer in high-income countries within 30 years, according to a new study. more
Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites. more
The days - or even weeks - spent waiting for the results of a cancer-screening test can feel like an eternity. Especially when early diagnosis and... more
Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites. Researchers report that the heavy reliance of these... more
With their ability to treat a wide a variety of diseases, spherical nucleic acids (SNAs) are poised to revolutionize medicine. But before these digitally designed nanostructures can reach... more
While a fraction of cancer patients treated with anti–PD-1 show durable therapeutic responses, most remain unresponsive, highlighting the need to better understand and improve these therapies. Using an in vivo screening approach... more
Developed by researchers at the University of Turku in Finland, an immunotherapeutic antibody therapy re-educates macrophages to activate passivated cytotoxic T cells to kill... more
Cancer patients who undergo chemotherapy could soon benefit from a new AI that is able to identify and predict the development of different combinations... more
In a study of mice and human brain tumors researchers searched for new treatments by exploring the reasons why some patients with gliomas live remarkably longer than others. The results suggested that certain patients'... more
Scientists from the University of Sheffield have discovered a compound that could be more effective in treating certain cancers than standard chemotherapy. more
With their ability to treat a wide a variety of diseases, spherical nucleic acids (SNAs) are poised to revolutionize medicine. But before these digitally designed nanostructures can reach their full... more
Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins and the Johns Hopkins University School of Medicine report... more
Aging is a leading risk factor for a number of debilitating conditions, including heart disease, cancer and Alzheimer's disease, to name a few. This makes the need for anti-aging therapies all the... more
Infections with a Human Papillomavirus cause 99 percent of cervical cancer cases, and the disease's first sign is often the appearance of precancerous lesions on a woman's cervix.... more
In a study of mice and human brain tumors researchers at the University of the Michigan, Ann Arbor, searched for new treatments by exploring the reasons why some patients with... more
Immunotherapy drugs such as PD-L1 checkpoint inhibitors represent the front-line treatment for kidney cancer. But immunotherapy is expensive, benefits only a subset of patients and is futile in the majority... more
Infections with a Human Papillomavirus (HPV) cause 99 percent of cervical cancer cases, and the disease's first sign is often the appearance of precancerous lesions on a woman's cervix. But bacteria may play an... more
Spherical nucleic acids are a class of personalized medicines for treating cancer and other diseasesSNAs are challenging to optimize because their structures can vary in many waysNorthwestern University... more
One of the frontiers of medical diagnostics is the race for more sensitive blood tests. The ability to detect extremely rare proteins could make... more
Researchers at the University of Montreal Hospital Research Centre have shown that immunotherapy treatments against cancer could reduce the amount of virus that persists in people on triple therapy. more
Cancer: The word alone evokes dread, anxiety, and fear. Accordingly, many women living with the disease and undergoing treatment experience chronic stress and depression. more
Every year, 4 million new cases of cancer are diagnosed in Europe. Advances in cancer treatment sometimes come at the cost of major adverse effects, and one of... more
Despite rapid advances in targeted therapies for cancer, tumors commonly develop resistance to treatment. When resistance emerges, tumor cells continue to grow unchecked, despite all attempts... more
Researchers have identified a very early marker of cardiac damage in patients undergoing therapy with anthracyclines, a family of drugs commonly used to treat cancer. This finding will... more
Lupron (leuprolide acetate) is a type of hormone therapy for people with prostate cancer. Lupron is an injection drug, and doctors often prescribe it in combination with radiation therapy or... more
Despite rapid advances in targeted therapies for cancer, tumors commonly develop resistance to treatment. When resistance emerges, tumor cells continue to grow unchecked, despite all attempts to slow cancer progression.... more
Cellular barcoding shows promise as a way to identify the few metastasis-driving cell variants from the thousands that are present in breast cancer tumors. more
Cancer researchers at the University of Bonn have reported significant progress in the treatment of glioblastoma. About one third of all patients suffer from a particular variant of... more
A combination of two drugs - one of them an immunotherapy agent - could become a new standard, first-line treatment for patients with metastatic kidney cancer, says an... more
Melanoma patients with a history of smoking cigarettes are 40 per cent less likely to survive their skin cancer than people who have never smoked, according to a... more
Columbia researchers have learned why some glioblastomas--the most common type of brain cancer--respond to immunotherapy. The findings could help identify patients who are most likely to benefit from treatment with... more
A combination of two drugs -- one of them an immunotherapy agent -- could become a new standard, first-line treatment for patients with metastatic kidney cancer,... more
If you think vaping is benign, think again. A small USC study shows that e-cig users develop some of the same cancer-related molecular changes in oral tissue as cigarette smokers, adding to... more
Researchers at the Medical University of South Carolina reveal a novel binding site for a class of anti-cancer drugs known as E1 inhibitors. This finding could... more
Researchers have identified a rare type of cancer cell that cannot make cholesterol, a key nutrient. By targeting this deficiency, scientists may be able... more
In an effort to understand how colibactin, a compound produced by certain strains of E. coli, may be connected to the development of colorectal... more
A cutting-edge technique called cellular barcoding has been used to tag, track and pinpoint cells responsible for the spread of breast cancer from the main tumour into the blood and other organs. more
Darla Shine has recently joined anti-vaccination campaigners by claiming that having measles as a child could protect against cancer in later life. more
The artificial intelligence software, created by researchers at Imperial College London and the University of Melbourne, has been able to predict the prognosis of patients with ovarian cancer... more
A research team at the University of Louisville has discovered that an immune checkpoint molecule they developed for cancer immunotherapy, also protects against future development of multiple types of cancer... more
Some patients with metastatic prostate cancer respond to a combination of immune checkpoint inhibitors after hormonal therapy and chemotherapy have failed, according to early results from... more
A new study indicates that both high-grade abnormal cellular changes (dysplasia) and esophageal adenocarcinoma (a form of cancer) have increased in the last 25 years among people with... more
For more than a decade, scientists have worked to understand the connection between colibactin, a compound produced by certain strains of E. coli, and colorectal cancer, but have been hampered... more
Cancer cells are, in some respects, impressive: They can grow relentlessly, sidestep the aging process by becoming immortal, and evade the immune system's persistent... more
Cervical cancer can be insidious. Changes to the cervix are often detected with a pap smear, but for those with limited access to health care, cervical... more
The scientific community has made great strides over the past decade in the development of a new class of cancer therapy called immunotherapy, a treatment that... more
In recent years, the number of targeted cancer drugs has continued to rise. However, conventional chemotherapeutic agents still play an important role in cancer treatment. more
An increasing number of new anti-cancer drugs are made available each year. During the authorization process, such new drugs usually undergo comparisons to one, but only... more
African-Americans still have the highest death rate and the lowest survival rate of any U.S. racial or ethnic group for most cancers. But the "cancer gap" between blacks... more
Survival after a diagnosis of heart failure in the United Kingdom has shown only modest improvement in the 21st century and lags behind other serious conditions, such as... more
Certain Escherichia coli strains residing in the human gut produce colibactin, a small-molecule genotoxin implicated in colorectal cancer pathogenesis. However, colibactin’s chemical structure and the molecular mechanism underlying its genotoxic effects have... more
Exposure to glyphosate--the world's most widely used, broad-spectrum herbicide and the primary ingredient in the weedkiller Roundup--increases the risk of some cancers... more
Researchers recently demonstrated that platinum nanoparticles can be used to kill liver cancer cells with greater selectivity than existing cancer drugs. more
Biomedical engineers have demonstrated how photoacoustic imaging can take the temperature of deep tissue more quickly and accurately than current techniques. This discovery is expected to play an important role... more
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