Cancer
New model developed to optimize and personalize radiotherapy for cancer patients  NEWS MEDICAL · 2 hours
A personalized approach to cancer treatment has become more common over the last several decades, with numerous targeted drugs approved to treat particular tumor types with... more
Ludwig study uncovers novel vulnerability in MYC-driven cancers  NEWS MEDICAL · 2 hours
A Ludwig Cancer Research study has uncovered a novel vulnerability in tumors that are driven by a common cancer gene known as MYC. Such cancers, it found, are highly dependent on the... more
Scratching the surface of how your brain senses an itch  SCIENCE DAILY · 3 hours
Light touch plays a critical role in everyday tasks, such as picking up a glass or playing a musical instrument, as well as for detecting the touch of,... more
Comparison of three similar frontline breast cancer drugs reveals important differences  SCIENCE DAILY · 4 hours
First head-to-head comparison of CDK4/6 inhibitors in cell line and animal models of breast cancer reveals important differences, including one drug that exhibits unique, potentially advantageous... more
Slow electrons to combat cancer  SCIENCE DAILY · 5 hours
Slow electons can be used to destroy cancer cells - but how exactly this happens has not been well understood. Now scientists have been able to demonstrate that a previously little-observed effect actually plays a pivotal role: Due... more
Slow electrons to combat cancer  PHYS.ORG · 6 hours
Ion beams are often used today in cancer treatment: this involves electrically charged atoms being fired at the tumour to destroy cancer cells. Although, it's not actually the ions themselves that cause the decisive damage. When ions penetrate... more
Enzyme that helps protect us from stress linked to liver cancer growth  SCIENCE DAILY · 6 hours
An enzyme induced by stress to help reduce production of damaging free radicals is also used by liver cancer to regulate two major cell... more
Enzyme induced by stress associated with liver cancer growth  NEWS MEDICAL · 7 hours
An enzyme induced by stress to help reduce production of damaging free radicals is also used by liver cancer to regulate two major cell proliferation pathways that enable the cancer... more
Single course of antibiotics may boost colon cancer risk  NEWS MEDICAL · 8 hours
In an extensive "data mining" analysis of British medical records, researchers at the Johns Hopkins Kimmel Cancer Center conclude that taking even a single course of antibiotics might boost--albeit slightly--the... more
'Kissing loops' in lncRNA essential for tumor suppressor function  NEWS MEDICAL · 12 hours
Human cells - like those of many other organisms - have developed mechanisms to protect us from cancer. more
UC San Diego researchers identify new therapeutic approach to kill cancer cells  NEWS MEDICAL · 12 hours
Epithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer therapies and to... more
New cannabis-based drug shows promise for pancreatic cancer  NEWS MEDICAL · 13 hours
Cancer of the pancreas is a particularly deadly cancer, claiming over 90% of its victims within 5 years from diagnosis. It resists most standard therapies, including surgery, chemotherapy, radiation therapy, immunotherapy and... more
Study opens up a new way for developing potential glioblastoma treatment  NEWS MEDICAL · 13 hours
A team led by Texas A&M University's College of Veterinary Medicine & Biomedical Sciences' researcher Dr. Stephen Safe has discovered a new pathway that may help... more
International study identifies new drug target for treating glioblastoma  NEWS MEDICAL · 14 hours
A new international study co-led by Cleveland Clinic has identified a new drug target for treating glioblastoma. This target is part of a never-before defined cellular pathway found to contribute... more
Medical News Today: Antibiotics and bowel cancer: Study finds link  MNT · 19 hours
A study looking at antibiotics and bowel cancer concludes that the drugs might increase the risk of colon cancer, but lower the risk of rectal cancer. more
New pathway for potential glioblastoma treatment  SCIENCE DAILY · 22 hours
A team has discovered a new pathway that may help suppress the development of glioblastoma tumors, one of the deadliest forms of cancer. more
The challenge: Make and purify a medical isotope that must be used the same day  PHYS.ORG · 22 hours
Two radioactive isotopes of the metallic element scandium, or Sc, appear to be ideal for visualizing, and then... more
[Focus] Neoantigen quality, not quantity  Science Magazine · 24 hours
Prioritizing expressed clonal neoantigens in genes required for cancer cell survival may reduce the likelihood of resistance to neoantigen therapies. more
Researchers convert pro-tumor macrophages into cancer killers  SCIENCE DAILY · 1 day
Researchers identified a new therapeutic approach in mouse models that halts drug resistance and cancer progression by using an antibody that induces the immune system via macrophages to seek and kill cancer cells. more
Chemical imaging used to aid diagnosis of colon cancer  PHYS.ORG · 1 day
Researchers have developed a method of chemical imaging which identifies colon cancer more accurately and efficiently than traditional methods. more
'Kissing loops' in RNA molecule essential for its role in tumor suppression  SCIENCE DAILY · 1 day
Researchers have discovered that the tumor suppressor MEG3 adopts a complex three-dimensional structure to fulfill its function. Furthermore, they were able to fine-tune its... more
New drug target for glioblastoma  SCIENCE DAILY · 1 day
A new international study has identified a new drug target for treating glioblastoma. This target is part of a never-before defined cellular pathway found to contribute to the spread and proliferation of a dangerous subset of cancer cells,... more
'Yin and yang' enzymes evolved over billions of years to protect against cancer  PHYS.ORG · 1 day
Researchers at the University of Dundee have made an important discovery about two enzymes that have evolved over billions of years to... more
MEG3 kissing loops essential for tumor suppression  PHYS.ORG · 1 day
A team of researchers in the Marcia group at EMBL Grenoble have discovered that the tumor suppressor MEG3 adopts a complex three-dimensional structure to fulfill its function. Furthermore, they were able to fine-tune its... more
Researchers make potential breakthrough in cancer drug development  PHYS.ORG · 1 day
A Victoria University of Wellington research team has developed an exciting new lead in the search for cancer treatments, creating alternative versions in the laboratory of a rare natural compound that targets... more
Drug that treat human breast cancer might also work for canine lung cancer  NEWS MEDICAL · 2 days
Despite those velvet paintings of poker-playing dogs smoking pipes, cigars and cigarettes, our canine friends really don't use tobacco. But like many... more
FDA clears its IND for new immunotherapeutic for treating prostate cancer  NEWS MEDICAL · 2 days
Calibr, the drug development division of Scripps Research, announced today that the U.S. Food and Drug Administration has cleared its investigational new drug application for CCW702,... more
Sociodemographic factors predict discriminatory oral cancer screening practices  NEWS MEDICAL · 2 days
Oral cancer accounts for 2 percent of reported malignancies and 1.2 percent of cancer-related deaths in the United States. more
New study provides a better understanding of Merkel cell carcinoma  NEWS MEDICAL · 2 days
Merkel cell carcinoma is a rare and aggressive type of skin cancer. Also called neuroendocrine carcinoma of the skin, it is much less common than most other types... more
Cancer survivors could be at greater risk of cardiovascular diseases  NEWS MEDICAL · 2 days
Over the last few decades, medical progress has led to the survival of many more people with cancer. However, a new study published in The Lancet shows that... more
Study identifies key epigenetic regulator that controls skin cell turnover  NEWS MEDICAL · 2 days
The outer layer of the skin completely replaces itself every two to four weeks, but when this process is blocked, cancer can grow. more
Ohio University scientists win $1.7 million grant for research on non-melanoma skin cancers  NEWS MEDICAL · 2 days
The National Institute of Environmental Health Sciences has awarded Ohio University scientists Shiyong Wu and Lingying Tong a five-year $1.7 million grant to advance... more
New insight into the immune system may help doctors to better fight cancer  NEWS MEDICAL · 2 days
Your immune system's natural killer cells recognize and attack two major kinds of danger - cells infected by viruses and cells affected... more
Medical News Today: Cancer more common in females with severe sleep apnea  MNT · 2 days
A new study of 20,000 adults with sleep apnea suggests that the risk of cancer could be 2–3 times higher among females with a... more
Medical News Today: What to know about HER2-negative breast cancer  MNT · 2 days
There are two main types of HER2-negative breast cancer: hormone receptor-positive and triple-negative. Many treatments exist, and prognosis varies. Learn more here. more
Antibiotic use linked to heightened bowel cancer risk  SCIENCE DAILY · 2 days
Antibiotic use (pills/capsules) is linked to a heightened risk of bowel (colon) cancer, but a lower risk of rectal cancer, and depends, to some extent, on the type and class of drug... more
Treating dogs with human breast cancer drug  SCIENCE DAILY · 2 days
Like many women who develop a particular type of breast cancer, the same gene -- HER2 -- also appears to be the cause of lung cancer in many dogs. Researchers found that neratinib --... more
Novel combination of drugs may overcome drug-resistant cancer cells  SCIENCE DAILY · 2 days
A new study suggests that a combination of three drugs, including a new class of glucose-6-phosphate dehydrogenase inhibitors, could overcome cross-therapy resistance. more
Largest genomic analysis could help improve treatment for Merkel cell carcinoma patients  NEWS MEDICAL · 2 days
Merkel cell carcinoma is a rare, aggressive skin tumor that is diagnosed in approximately 2,000 people each year in the United States. more
A new path to cancer therapy: developing simultaneous multiplexed gene editing technology  SCIENCE DAILY · 2 days
Scientists have developed a new gene editing system that could be used for anticancer immunotherapy through the simultaneous suppression of proteins that interfere with... more
Guidelines say more women may need breast cancer gene test  ABC NEWS · 2 days
New guidelines say more women may benefit from gene testing for hereditary breast or ovarian cancer more
A new path to cancer therapy: Developing simultaneous multiplexed gene editing technology  PHYS.ORG · 2 days
Dr. Mihue Jang and her group at the Center for Theragnosis of the Korea Institute of Science and Technology (KIST, President Byung-gwon Lee) announced... more
Simple test could help diagnose glioblastoma  NEWS MEDICAL · 2 days
Scientists at the University of Sussex could be a step closer to developing the first-ever blood test to diagnose the most aggressive type of brain cancer, glioblastoma. more
FDA approves cold atmospheric plasma technology for first-ever use in clinical trial  NEWS MEDICAL · 3 days
Cold atmospheric plasma technology, currently the only way to remove microscopic cancer tumors remaining from surgery, has been approved by the U.S. Food and... more
Dacomitinib treatment for lung cancer increases overall survival but has more side effects  NEWS MEDICAL · 3 days
Since its approval in April 2019, dacomitinib has been available for the first-line treatment of adult patients with locally advanced or metastatic... more
Study: Blocking inflammatory pathway could prevent melanoma brain metastasis  NEWS MEDICAL · 3 days
Brain metastases are among the deadliest tumor metastases, with a median survival period of less than one year, and the incidence of brain metastasis is rising. more
Lipid signaling pathway may enhance T cell-mediated immunotherapy  NEWS MEDICAL · 3 days
The immune system surveils our body looking for things that don't belong, often bacteria and viruses. While cancer cells are abnormal cells that undergo unregulated cell growth, they are good at evading... more
Study uncovers potential new treatment approach for lung cancer  NEWS MEDICAL · 3 days
Lung cancer is the second most common cancer found in both men and women. It is estimated there will be roughly 228,000 new lung cancer cases this year, and nearly... more
Physical activity in adolescence associated with 39% reduction in risk of colorectal adenoma  NEWS MEDICAL · 3 days
The effects of more than 60 minutes of moderate daily physical exercise, such as walking, accumulate throughout life and are associated with... more
Study shows synergistic effects of drugs that inhibit cell division in pancreatic cancer  NEWS MEDICAL · 3 days
Pancreatic cancer is one of the deadliest cancers, with patients surviving on average less than a year once the disease has spread. more
HCI unveils new mobile outreach vehicle to offer education, cancer screening services  NEWS MEDICAL · 3 days
Today Huntsman Cancer Institute at the University of Utah unveiled the Cancer Screening and Education bus. more
Possible new treatment strategy for lung cancer  SCIENCE DAILY · 3 days
It is estimated there will be roughly 228,000 new lung cancer cases this year, and nearly 30% of those patients will have mutations in the KRAS pathway. This type of mutation makes the cancer... more
New lipid signaling target may improve T cell immunotherapy  SCIENCE DAILY · 3 days
T cell immunotherapy uses the immune system to kill cancer cells. To increase the efficacy of this new treatment, researchers aimed to discover a master regulator of T cell fate.... more
Targeting cell division in pancreatic cancer  SCIENCE DAILY · 3 days
Study provides new evidence of synergistic effects of drugs that inhibit cell division and support for further clinical trials. more
Interregional differences in somatic genetic landscape diversify prognosis in glioblastoma  SCIENCE DAILY · 3 days
Researchers have conducted the largest-ever retrospective cohort study for Japanese patients with glioblastoma (GBM), proposing an underlying prognosis biomarker responsible for the survival difference between two cohorts: an... more
Graphene nanoflakes: A new tool for precision medicine  PHYS.ORG · 3 days
Chemists funded by the SNSF have created a new compound for flexible drug delivery that specifically targets prostate cancer cells. Incorporating four different molecules, the compound prevents tumor cells from multiplying, can... more
Study provides new insight into regional survival differences in glioblastoma  NEWS MEDICAL · 3 days
A team of researchers from Osaka University, in cooperation with the Institute for Clinical Research and medical institutes participating in the Kansai Molecular Diagnosis Network for CNS Tumors,... more
Chemists develop new approach based on graphene nanoflakes for drug delivery  NEWS MEDICAL · 4 days
Chemists funded by the SNSF have created a new compound for flexible drug delivery that specifically targets prostate cancer cells. Incorporating four different molecules, the compound... more
Graphene nanoflakes: a new tool for precision medicine  nanowerk · 4 days
Chemists have created a new compound for flexible drug delivery that specifically targets prostate cancer cells. Incorporating four different molecules, the compound prevents tumour cells from multiplying, can be detected by medical... more
Study explores if fecal transplants can improve outcomes in melanoma patients  NEWS MEDICAL · 4 days
A multidisciplinary team at Lawson Health Research Institute is exploring whether fecal transplants can improve outcomes in melanoma patients treated with immunotherapy. more
New way to help dermatologists determine patient's risk of developing melanoma  NEWS MEDICAL · 4 days
University of Queensland scientists have identified a way to help dermatologists determine a patient's risk of developing melanoma. more
Protein governing platinum-resistant ovarian cancer identified  NEWS MEDICAL · 4 days
The extracellular regulated kinase (ERK) protein is an important mechanism behind platinum-resistance in platinum-resistant ovarian cancer, according to a study from a research team at the George Washington University (GW) Cancer Center. more
Research finds lack of racial diversity in clinical trials for cancer drugs  NEWS MEDICAL · 5 days
New research published this week in JAMA Oncology has found a lack of racial and ethnic diversity in clinical trials for cancer drugs. more
Medical News Today: The power of electromagnetic energy on breast cancer cells  MNT · 5 days
Electromagnetic energy could be used to halt the movement of breast cancer cells, reducing metastatic cases. New research explains how. more
Medical News Today: Simple dietary changes may reduce cancer risk, increase lifespan  MNT · 6 days
The health benefits of fruit and vegetables are partly due to flavonoids. A new study concludes that consuming more flavonoids each day may extend... more
Numbers count in the genetics of moles and melanomas  SCIENCE DAILY · 6 days
Scientists have identified a way to help dermatologists determine a patient's risk of developing melanoma. more
Fluorescent carbon dots could make cancer treatment safer and more effective  nanowerk · 6 days
Researchers develop new technique with carbon nanoparticles to make photodynamic therapy safer, cheaper and more effective. more
Tiny fluorescent carbon dots could make cancer treatment safer and more effective  PHYS.ORG · 6 days
A pioneering new technique that could make light-based cancer treatment more effective and safer for patients, while reducing its cost, has been developed by... more
Gold Coast Biobank at Griffith University boosts medical research  NEWS MEDICAL · 6 days
Better treatment and management of chronic diseases such as breast cancer, heart disease and Alzheimer’s is one step closer with the official opening of Gold Coast Biobank at Griffith University’s Gold Coast campus... more
Targeted pancreatic cancer drug shows promise in clinical trials  NEWS MEDICAL · 6 days
Researchers have conducted clinical trials with a new drug targeting pancreatic cancer and the initial results are promising. more
Non-invasive electrical stimulation alters blood flow in brain tumors  SCIENCE DAILY · 7 days
Scientists demonstrated that applying low-intensity electrical stimulation to the brains of patients with tumors resulted in decreased blood flow within tumors while leaving the rest of the brain unchanged. Although... more
Gleevec (imatinib)  MNT · 7 days
Gleevec (imatinib) is a brand-name prescription medication. It’s used to treat certain types of blood cancers, including Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML). It’s also used to treat certain types of skin cancer and gastrointestinal cancer. Learn about side... more
Mutations linked to familial pancreatic cancer  SCIENCE DAILY · 1 week
A new study finds genetic mutations associated with hereditary forms of pancreatic cancer and mechanism by which these mutations may contribute to the development of tumors. more
How cells override genetic changes  SCIENCE DAILY · 1 week
A new discovery could lead researchers to a more effective way to treat pancreatic cancer. more
Nanoscale 'glass' bottles could enable targeted drug delivery  SCIENCE DAILY · 1 week
Tiny silica bottles filled with medicine and a special temperature-sensitive material could be used for drug delivery to kill malignant cells only in certain parts of the body, according to a new... more
More cancer cases among women with sleep apnea  SCIENCE DAILY · 1 week
Women with severe sleep apnea appear to be at an elevated risk of getting cancer, a study shows. No causal relationship is demonstrated, but the link between nocturnal hypoxia in women and... more
Nanoscale 'glass' bottles could enable targeted drug delivery  PHYS.ORG · 1 week
Tiny silica bottles filled with medicine and a special temperature-sensitive material could be used for drug delivery to kill malignant cells only in certain parts of the body, according to a study... more
Nanocapsule reaches cancer that has spread to central nervous system in mice  nanowerk · 1 week
Cancer that has spread to the central nervous system is notoriously difficult to treat. Now, researchers have developed a drug delivery system that breaks... more
Nanoscale 'glass' bottles could enable targeted drug delivery  nanowerk · 1 week
Tiny silica bottles filled with medicine and a special temperature-sensitive material could be used for drug delivery to kill malignant cells only in certain parts of the body. more
Count and location of moles on the body influenced by genetic makeup  NEWS MEDICAL · 1 week
A study published this week in the journal Pigment Cell & Melanoma Research has found that genes have a greater influence than previously thought... more
New drug to treat pancreatic cancer shows promising results in clinical trial  NEWS MEDICAL · 1 week
A clinical trial testing a new drug in pancreatic cancer had promising initial results, report researchers from the University of Michigan Rogel Cancer Center. more
Researchers develop new strategy to target metastases in lymph nodes  NEWS MEDICAL · 1 week
Metastasis, in which cancer cells break free from the primary tumor and form tumors at other sites, worsens the prognosis for many cancer patients. more
Medical News Today: Can itchy armpits be a sign of cancer?  MNT · 1 week
Itchy armpits may occasionally be due to cancer, although there are many more likely causes. Infections and underlying skin conditions are some other reasons. Learn more... more
Medical News Today: How might the keto diet help treat cancer?  MNT · 1 week
Preclinical research in mice has examined the effect of ketogenic diet-induced glucose restriction on a certain type of cancer cell. more
Nanocapsule reaches cancer that has spread to central nervous system in mice  PHYS.ORG · 1 week
Cancer that has spread to the central nervous system is notoriously difficult to treat. Now, UCLA researchers have developed a drug delivery system that... more
Reduction of intratumoral brain perfusion by noninvasive transcranial electrical stimulation  Science Magazine · 1 week
Malignant brain neoplasms have a poor prognosis despite aggressive treatments. Animal models and evidence from human bodily tumors reveal that sustained reduction in tumor perfusion via electrical stimulation... more
BRAF inhibitors promote intermediate BRAF(V600E) conformations and binary interactions with activated RAS  Science Magazine · 1 week
Oncogenic BRAF mutations initiate tumor formation by unleashing the autoinhibited kinase conformation and promoting RAS-decoupled proliferative RAF-MEK-ERK signaling. We have engineered luciferase-based biosensors to... more
Engineered collagen-binding serum albumin as a drug conjugate carrier for cancer therapy  Science Magazine · 1 week
Serum albumin (SA) is used as a carrier to deliver cytotoxic agents to tumors via passive targeting. To further improve SA’s tumor targeting capacity,... more
[Research Articles] MDM2 antagonists overcome intrinsic resistance to CDK4/6 inhibition by inducing p21  Science Magazine · 1 week
Intrinsic resistance of unknown mechanism impedes the clinical utility of inhibitors of cyclin-dependent kinases 4 and 6 (CDK4/6i) in malignancies other than... more
Nanoparticle therapy targets lymph node metastases  nanowerk · 1 week
Researchers have developed a strategy to target metastases in lymph nodes for destruction, before they can cause cancer at other locations. more
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