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Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation
NEWS MEDICAL A group of Massachusetts General Hospital investigators is proposing that targeting immune checkpoints - molecules that regulate the activity of the immune system - in immune cells called microglia could... 13 hours
Alzheimer's: These psychiatric symptoms may be an early sign
MNT A postmortem study of brain tissue tests and interviews of those close to the deceased ties some psychiatric symptoms to early Alzheimer's disease. 22 hours
Medical News Today: Alzheimer's: These psychiatric symptoms may be an early sign
MNT A postmortem study of brain tissue tests and interviews of those close to the deceased ties some psychiatric symptoms to early Alzheimer's disease. 21 hours
Regulating microglial activity may reduce inflammation in neurodegenerative diseases
SCIENCE DAILY A group of investigators is proposing that targeting immune checkpoints -- molecules that regulate the activity of the immune system -- in immune cells called microglia could reduce the inflammatory... 24 hours
Chronic sleep disruption in early adult life accelerates AD-related tau pathology
NEWS MEDICAL Lack of sleep during adolescence and early adulthood accelerates Alzheimer’s disease-related tau pathology, finds a study of male and female mice published in JNeurosci. 1 day
Down syndrome may hold important clues to onset of Alzheimer's disease
NEWS MEDICAL At first glance, Down syndrome and Alzheimer's disease, two severe brain abnormalities, may seem to have little in common. Down syndrome is a hereditary disease, the... 1 day
Neuropsychiatric symptoms related to earliest stages of Alzheimer's brain pathology
NEWS MEDICAL UC San Francisco researchers, in collaboration with the unique Brazilian Biobank for Aging Studies at the University of São Paulo, have shown that the earliest stages of the... 3 days
Study reveals potential to monitor progression of Alzheimer’s disease by measuring brain antioxidant levels
NEWS MEDICAL In a breakthrough human study, anti-oxidant, glutathione, which protects the brain from stress, has been found to be significantly depleted... 3 days
Early changes to synapse gene regulation may cause Alzheimer's disease
SCIENCE DAILY New research has revealed a role for splicing proteins in the pathology of Alzheimer's disease. Increased phosphorylation of the SRRM2 protein, seen in AD mouse models and human... 6 days
Team simulates how Alzheimer's disease spreads through the brain
PHYS.ORG VIDEO For the first time, scientists have developed a computer simulation of how clumps of defective proteins in neurodegenerative diseases like Alzheimer's spread through the brain, much of the time in... 6 days
Researchers model how toxic proteins course through the brain, lead to disease
PHYS.ORG Many neurodegenerative diseases spread by hijacking the brain's connective circuitry to transport toxic proteins, which gradually accumulate and trigger symptoms of dementias. Now, researchers... 6 days
Findings offer new insight into early changes that occur during AD pathology
NEWS MEDICAL Alzheimer's disease (AD) is the most common form of dementia, involving memory loss and a reduction in cognitive abilities. 6 days
Antidepressants can be used to treat Alzheimer’s disease
NEWS MEDICAL Scientists at the University of Waterloo have discovered that antidepressant medications can be used to treat Alzheimer’s disease. 6 days
Exposure to magnetite particles is unlikely to contribute to Alzheimer’s disease
NEWS MEDICAL A 2016 study showed that exposure to urban pollution involving magnetite particles played a role in the development of Alzheimer's disease. 6 days
New appropriate use criteria for lumbar puncture in Alzheimer's diagnosis
SCIENCE DAILY In preparation for more tools that detect and measure the biology associated with Alzheimer's and other dementias earlier and with more accuracy, experts have published appropriate use criteria... 7 days
Questioning the link between pollution by magnetite particles and Alzheimer's disease
PHYS.ORG A 2016 study showed that exposure to urban pollution involving magnetite particles played a role in the development of Alzheimer's disease. It began from the hypothesis... 1 week
Personalized goal setting to improve dementia care
NEWS MEDICAL Dementia is a health condition that affects your memory in ways that can make it difficult to carry out your usual daily tasks. The most common cause of dementia is Alzheimer's disease, which causes... 1 week
Antiepileptic drug use associated with elevated stroke risk in Alzheimer’s patients
NEWS MEDICAL Antiepileptic drug use is associated with an increased risk of stroke among persons with Alzheimer’s disease, according to a new study from the University of Eastern... 1 week
New AUC published for lumbar puncture and spinal fluid analysis in Alzheimer's diagnosis
NEWS MEDICAL In preparation for more tools that detect and measure the biology associated with Alzheimer's and other dementias earlier and with more accuracy,... 1 week
Scientists identify new biomarker for Alzheimer's disease of sporadic origin
NEWS MEDICAL The objective of the research, undertaken in the laboratories of the IBPM, is to develop a model for studying Alzheimer's disease of sporadic origin, in other words, not... 1 week
What is the difference between dementia and Alzheimer's?
MNT Dementia is an umbrella term that describes symptoms affecting memory and cognitive function. Alzheimer’s disease is a specific, and the most common, type of dementia. The conditions overlap in terms of symptoms,... 1 week
Medical News Today: What is the difference between dementia and Alzheimer's?
MNT Dementia is an umbrella term that describes symptoms affecting memory and cognitive function. Alzheimer’s disease is a specific, and the most common, type of dementia. The... 1 week
Scientists create new map of brain region linked to Alzheimer's disease
SCIENCE DAILY Scientists have now completed an exceptionally detailed map of the brain's memory bank, the hippocampus. Intricate insight into hippocampus' structure and function opens new opportunities to... 1 week
Periodontal disease bacteria may kick-start Alzheimer's
SCIENCE DAILY Long-term exposure to periodontal disease bacteria causes inflammation and degeneration of brain neurons in mice that is similar to the effects of Alzheimer's disease in humans. Periodontal disease may be an initiator of Alzheimer's. 2 weeks
Mouse study mirrors human findings that link chemotherapy and APOE4 to cognitive issues
SCIENCE DAILY A chemotherapy drug commonly used to treat breast cancer alters brain structure and function in mice that express the human APOE4 gene,... 2 weeks
Scientists get the drop on the cell's nucleus
PHYS.ORG A team of physicists has devised a novel strategy that uses naturally occurring motions inside the human cell nucleus to measure the physical properties of the nucleus and its components. The method,... 2 weeks
AI could be used to diagnose Alzheimer's years before symptoms appear
NEWS MEDICAL An Artificial Intelligence (AI) algorithm has been trained to pick up early signs of cognitive decline, which could result in Alzheimer’s disease (AD). 2 weeks
AI could predict cognitive decline leading to Alzheimer's disease in the next five years
SCIENCE DAILY A team of scientists has successfully trained a new artificial intelligence (AI) algorithm to make accurate predictions regarding cognitive decline... 2 weeks
Periodontal disease may be an initiator of Alzheimer's
NEWS MEDICAL Long-term exposure to periodontal disease bacteria causes inflammation and degeneration of brain neurons in mice that is similar to the effects of Alzheimer's disease in humans, according to a new study from... 2 weeks
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Team simulates how Alzheimer's disease spreads through the brain
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