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One step closer toward a treatment for Alzheimer's disease?
SCIENCE DAILY Scientists have characterized a new class of drugs as potential therapeutics for Alzheimer's disease and discovered a piece in the puzzle of how they would work. 18 hours
New imaging system offers better way to monitor brain changes from Alzheimer's in mouse models
NEWS MEDICAL An estimated 5.5 million Americans live with Alzheimer's disease, a type of dementia that causes problems with memory,... 1 day
New imaging approach maps whole-brain changes from Alzheimer's disease in mice
SCIENCE DAILY A new imaging system that offers a better way to monitor the brain changes indicative of Alzheimer's in mouse models of the disease could help speed... 2 days
New imaging approach maps whole-brain changes from Alzheimer's disease in mice
PHYS.ORG An estimated 5.5 million Americans live with Alzheimer's disease, a type of dementia that causes problems with memory, thinking and behavior. Although treatments can slow the... 2 days
Findings reveal how seizures can have lasting detrimental effects on memory
NEWS MEDICAL Although it's been clear that seizures are linked to memory loss and other cognitive deficits in patients with Alzheimer's disease, how this happens has been puzzling.... 2 days
Report: Global burden of neurological disorders in today’s world
NEWS MEDICAL Globally, the burden of neurological disorders (Alzheimer's disease, Parkinson's disease, stroke, epilepsy etc) has increased substantially over the past 25 years. 4 days
How a green tea compound could prevent Alzheimer's
MNT Researchers reveal how a compound in green tea called EGCG prevents the formation of toxic beta-amyloid plaques, which are a hallmark of Alzheimer's. 6 days
Medical News Today: How a green tea compound could prevent Alzheimer's
MNT Researchers reveal how a compound in green tea called EGCG prevents the formation of toxic beta-amyloid plaques, which are a hallmark of Alzheimer's. 6 days
Scientists help show links between genes, body tissues
SCIENCE DAILY A research team is assessing how a person's genetic profile affects his body. The results could help show how individual genetic differences contribute to disease and guide treatments for heritable disorders such... 6 days
New mechanism detected in Alzheimer's disease
SCIENCE DAILY Researchers have discovered a cellular mechanism that may contribute to the breakdown of communication between neurons in Alzheimer's disease. In the brain tissue of Alzheimer's patients, the RNAs that encode synaptic proteins are degraded more rapidly... 6 days
McGill researchers discover new cellular mechanism in Alzheimer's disease
NEWS MEDICAL McGill University researchers have discovered a cellular mechanism that may contribute to the breakdown of communication between neurons in Alzheimer's disease. 6 days
Cellular reprograming implicated in model of Alzheimer's disease
MIT Neuroscientists identify genetic changes in microglia in a mouse model of neurodegeneration and Alzheimer's disease. 7 days
Scalable synthesis of bryostatin 1 and analogs, adjuvant leads against latent HIV
Science Magazine Bryostatin 1 is an exceedingly scarce marine-derived natural product that is in clinical development directed at HIV/AIDS eradication, cancer immunotherapy, and the treatment of... 7 days
Dementia patient at center of spoon-feeding controversy dies
NEWS MEDICAL An Oregon woman with Alzheimer's disease, whose husband claimed she was kept alive with spoon-feeding against her written wishes, has died. 1 week
Medical News Today: Menopause may trigger Alzheimer's disease
MNT A new study looked at the metabolic changes in the brains of menopausal and perimenopausal women and found potential triggers for Alzheimer's disease. 1 week
Menopause may trigger Alzheimer's disease
MNT A new study looked at the metabolic changes in the brains of menopausal and perimenopausal women and found potential triggers for Alzheimer's disease. 1 week
New smell test could aid early detection of Alzheimer's and Parkinson's
SCIENCE DAILY Problems with olfaction have been linked to a variety of health conditions. Scientists have developed new tests to detect smell loss more reliably. 1 week
Menopause triggers metabolic changes in brain that may promote Alzheimer's
SCIENCE DAILY Menopause causes metabolic changes in the brain that may increase the risk of Alzheimer's disease, a team of scientists has shown in new research. 1 week
New smell test could help improve early diagnosis of Alzheimer's, Parkinson's diseases
NEWS MEDICAL Nisha Pradhan was seven when she began to suspect she was missing out on something. Her sister seemed to have an uncanny knack for... 1 week
Patients unaware of memory loss more likely to develop Alzheimer's disease, study shows
NEWS MEDICAL While memory loss is an early symptom of Alzheimer's disease, its presence doesn't mean a person will develop dementia. A new study... 1 week
Scientists find new way to produce brain cells from single iPSC
NEWS MEDICAL Li Gan, PhD, wants to find treatments to help patients with Alzheimer's disease. Like most researchers, she's hit a few major roadblocks. 1 week
Menopause causes metabolic changes in the brain that may increase Alzheimer's risk
NEWS MEDICAL Menopause causes metabolic changes in the brain that may increase the risk of Alzheimer's disease, a team from Weill Cornell Medicine and the University... 1 week
Being unaware of memory loss predicts Alzheimer's disease, new study shows
SCIENCE DAILY While memory loss is an early symptom of Alzheimer's disease, its presence doesn't mean a person will develop dementia. A new study has found a clinically... 1 week
Alzheimer's gene can protect against and promote neurological damage
NEWS MEDICAL Scientists drilling down to the molecular roots of Alzheimer's disease have encountered a good news/bad news scenario. A major player is a gene called TREM2, mutations of which can substantially... 1 week
Alzheimer's gene poses both risk and benefits
SCIENCE DAILY Scientists studying the molecular roots of Alzheimer's disease have encountered a good news/bad news scenario. The bad news is that in the early stages of the disease, high-risk TREM2 variants can hobble the immune... 1 week
Molecular basis for memory and learning: Brain development and plasticity share similar signalling pathways
SCIENCE DAILY Learning and memory are two important functions of the brain that are based on the brain’s plasticity. Scientists now report... 1 week
Medical News Today: Dementia: Study helps to unravel the cause of brain cell death
MNT Researchers suggest that the loss of a gene called LSD1 plays a role in the brain cell death that occurs... 1 week
Researchers propose LSD1 protein as central player in Alzheimer's and FTD
NEWS MEDICAL Removal of a regulatory gene called LSD1 in adult mice induces changes in gene activity that that look unexpectedly like Alzheimer's disease, scientists have discovered. 1 week
How brain cells die in Alzheimer's and FTD
SCIENCE DAILY Removal of a regulatory gene called LSD1 in adult mice induces changes in gene activity that that look unexpectedly like Alzheimer's. Another surprise: LSD1 is tangled up in brain samples from humans... 1 week
New $7.6 million NIA grant awarded to IU for Longitudinal Early-onset AD Study
NEWS MEDICAL Indiana University School of Medicine has been awarded a one-year, $7.6 million grant from the National Institute on Aging to establish a... 1 week
Dementia: Study helps to unravel the cause of brain cell death
MNT Researchers suggest that the loss of a gene called LSD1 plays a role in the brain cell death that occurs with Alzheimer's and frontotemporal dementia. 1 week
Tactile hallucinations: Causes, diagnosis, and treatment
MNT Learn more about tactile hallucinations and its symptoms. Including more on causes such as Alzheimer’s disease, Lewy body dementia, and delirium tremens. 2 weeks
Medical News Today: Tactile hallucinations: Causes, diagnosis, and treatment
MNT Learn more about tactile hallucinations and its symptoms. Including more on causes such as Alzheimer’s disease, Lewy body dementia, and delirium tremens. 2 weeks
New microcapsules to enhance the efficiency of genome-editing
PHYS.ORG Researchers from Tomsk Polytechnic University jointly with their colleagues from St. Petersburg, Hamburg and London have found that polymer and hybrid silica-coated microcapsules are more efficient in genome-editing when applying CRISPR-Cas9. In... 2 weeks
Fibril structure of amyloid-{beta}(1-42) by cryo-electron microscopy
Science Magazine Amyloids are implicated in neurodegenerative diseases. Fibrillar aggregates of the amyloid-β protein (Aβ) are the main component of the senile plaques found in brains of Alzheimer’s disease patients. We present the structure of an... 2 weeks
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