Alzheimers
Studies identify mechanism key to removal of protein aggregates from cells  PHYS.ORG · 3 days
Massachusetts General Hospital (MGH) investigators have discovered the mechanism by which cells sense dysfunction of the proteasome—a cellular component that degrades unneeded or defective proteins—and respond... more
Secondary nucleation and elongation occur at different sites on Alzheimers amyloid-{beta} aggregates  Science Magazine · 4 days
The aggregates of the Aβ peptide associated with Alzheimer’s disease are able to both grow in size as well as generate, through secondary nucleation,... more
[Editors' Choice] Targeting senescence within the Alzheimers plaque  Science Magazine · 4 days
Amyloid β drives senescence of oligodendrocyte progenitor cells, presenting a potential therapeutic target. more
Alzheimer's: Synthetic protein blocks toxic beta-amyloid  MNT · 5 days
Scientists have designed a protein that folds into alpha sheets that can block toxic beta-amyloid in brain cells before it forms into large clumps. more
Medical News Today: Alzheimer's: Synthetic protein blocks toxic beta-amyloid  MNT · 5 days
Scientists have designed a protein that folds into alpha sheets that can block toxic beta-amyloid in brain cells before it forms into large clumps. more
Senior's weakness for scams may be warning sign of dementia  ABC NEWS · 6 days
Researchers say seniors who aren't on guard against scams also might be at risk for developing Alzheimer's disease more
APOE gene impacts sleep depending on gender and severity of Alzheimer's  NEWS MEDICAL · 6 days
The gene most often associated with risk of Alzheimer's Disease impacts sleep depending on gender and the severity of Alzheimer's in a patient, suggests a study... more
Researchers observe correlation between abnormal proteins and aggressive behavior in dementia  NEWS MEDICAL · 1 week
Researchers at Lund University in Sweden have together with American colleagues studied deceased patients who were diagnosed with Alzheimer's disease or frontotemporal dementia. more
Neuroscientists identify factors for maintaining healthy memory at any age  NEWS MEDICAL · 2 weeks
University of Alberta neuroscientists have identified different factors for maintaining healthy memory and for avoiding memory decline in those over age 55, according to a new study. The... more
Aging gracefully: Study identifies factors for healthy memory at any age  SCIENCE DAILY · 2 weeks
Neuroscientists have identified different factors for maintaining healthy memory and for avoiding memory decline in those over age 55, according to a new study. The results... more
Stimulating parvalbumin-containing cells causes surprising changes in blood volume, flow  NEWS MEDICAL · 2 weeks
Alzheimer's disease and schizophrenia are some of the most common brain disorders and have been associated with problems in cells that contain a type of protein, called parvalbumin. more
Scientists develop technique to clear abnormal tau protein from human neurons  NEWS MEDICAL · 2 weeks
Harnessing a probe used to image the brain in diagnosing Alzheimer's disease and related forms of dementia, scientists at Dana-Farber Cancer Institute and Massachusetts General Hospital... more
Gum disease bacterium releases toxins that may cause Alzheimer's  NEWS MEDICAL · 2 weeks
Researchers have provided the strongest evidence to date that a bacterium involved in periodontitis contributes to the development of Alzheimer’s disease, rheumatoid arthritis and aspiration pneumonia. more
New research finds anti-inflammatory drugs to be ineffective to prevent Alzheimer’s  NEWS MEDICAL · 2 weeks
Researchers have known for decades that inflammation accompanies Alzheimer's disease brain lesions. Several early studies suggested that "super-aspirins" or Nonsteroidal anti-inflammatory drugs could help avoid the... more
Gum bacteria implicated in Alzheimer's and other diseases  SCIENCE DAILY · 2 weeks
Researchers are reporting new findings on how bacteria involved in gum disease can travel throughout the body, exuding toxins connected with Alzheimer's disease, rheumatoid arthritis and aspiration pneumonia. They detected evidence of... more
Eyes reveal early Alzheimer's disease  SCIENCE DAILY · 2 weeks
Reduced blood capillaries in the back of the eye may be a new, noninvasive way to diagnose early cognitive impairment, the precursor to Alzheimer's disease in which individuals become forgetful, reports a new study. Scientists detected these vascular... more
NSAIDs ineffective for treatment or prevention of Alzheimer's disease  NEWS MEDICAL · 2 weeks
Researchers have known for decades that inflammation accompanies Alzheimer's disease (AD) brain lesions. more
Vascular changes in the eye reveal early cognitive impairment  NEWS MEDICAL · 2 weeks
Reduced blood capillaries in the back of the eye may be a new, noninvasive way to diagnose early cognitive impairment, the precursor to Alzheimer's disease in which individuals become forgetful,... more
Scientists to investigate link between sleep and dementia at UEA’s new sleep unit  NEWS MEDICAL · 2 weeks
Sleep disturbances are common in dementia. But it is not yet known whether Alzheimer's causes sleep problems, or whether sleep problems could... more
PET images of microglial activation levels could better predict Alzheimer's disease progression  NEWS MEDICAL · 2 weeks
Researchers have discovered a way to better predict progression of Alzheimer's disease. By imaging microglial activation levels with positron emission tomography, researchers were able... more
New PET imaging biomarker could better predict progression of Alzheimer's disease  SCIENCE DAILY · 2 weeks
Researchers have discovered a way to better predict progression of Alzheimer's disease. A study utilizing positron emission tomography to image microglial activation levels showed that these... more
Protein key to charcot-marie-tooth, other nerve diseases  SCIENCE DAILY · 2 weeks
A new study provides critical insight into a little-known, yet relatively common, inherited neurological condition called Charcot-Marie-Tooth disease. The findings point to a pathway to possible treatments for this disease and better understanding of... more
ADDF’s new initiative aims to advance digital tools for Alzheimer's and dementias  NEWS MEDICAL · 3 weeks
As part of its Diagnostics Accelerator research program, the Alzheimer's Drug Discovery Foundation announced today a new initiative that aims to fast-track the development... more
Drug that looks at Alzheimer’s differently ready for its first in-human testing  NEWS MEDICAL · 3 weeks
Alzheimer's disease wreaks emotional havoc on patients, who are robbed of their memories, their dignity, and their lives. more
Alzheimer's diagnosis, management improved by brain scans  SCIENCE DAILY · 3 weeks
A first-of-its-kind national study has found that a form of brain imaging that detects Alzheimer's-related 'plaques' significantly influenced clinical management of patients with mild cognitive impairment and dementia. more
Dementia: Amyloid PET scans can improve diagnosis and care  MNT · 3 weeks
Using brain scans that can detect hallmarks of Alzheimer's could improve diagnosis and clinical care of people with dementia and mild cognitive impairment. more
Medical News Today: Dementia: Amyloid PET scans can improve diagnosis and care  MNT · 3 weeks
Using brain scans that can detect hallmarks of Alzheimer's could improve diagnosis and clinical care of people with dementia and mild cognitive impairment. more
How RNA PoII maintains accurate transcription  SCIENCE DAILY · 3 weeks
Scientists have recently uncovered the mechanisms of how RNA polymerase II performs intrinsic cleavage reaction to proofread RNA transcriptions, shedding light on how misregulation of accurate transcription can lead to diseases including cancer and Alzheimer's disease. more
3D-printed transparent skull provides a window to the brain  SCIENCE DAILY · 3 weeks
Researchers have developed a unique 3D-printed transparent skull implant for mice that provides an opportunity to watch activity of the entire brain surface in real time. The device allows fundamental... more
Amyloid PET associated with changes in clinical management of patients with dementia  NEWS MEDICAL · 3 weeks
Amyloid (abnormal protein) plaques in the brain are a feature of Alzheimer disease and imaging the brain with positron emission tomography can detect them. more
UCL scientists discover key brain region for navigating familiar places  NEWS MEDICAL · 3 weeks
UCL scientists have discovered the key brain region for navigating well-known places, helping explain why brain damage seen in early stages of Alzheimer's disease can cause such severe... more
Neuroscientists question effectiveness of using electrical currents to improve memory  NEWS MEDICAL · 3 weeks
The effectiveness of applying electrical currents to the brain to improve memory and enhance cognitive ability - often used to treat Alzheimer's patients and children with developmental disorders... more
EU-funded researchers develop 'nano-vehicle' to deliver life-saving drugs  NEWS MEDICAL · 3 weeks
Despite many successes, modern medicine is still struggling to find effective treatments for serious pathologies such as cancer and neurodegenerative and inflammatory diseases. For Alzheimer’s disease, for example, only 30% of patients... more
Michigan State University receives $1.8 million NIH grant to improve brain implants  NEWS MEDICAL · 3 weeks
Michigan State University has landed a $1.8 million National Institutes for Health R01 grant to improve brain implants - "electroceuticals" used to treat Alzheimer's,... more
Scientists identify two, extremely rare genetic variants linked to Alzheimer disease  NEWS MEDICAL · 3 weeks
Researchers have identified two, extremely rare genetic variants linked to Alzheimer disease (AD) for the first time. more
Scientists Find Cyanobacterial Neurotoxin and Amyloid Plaques in Brains of Stranded Dolphins  SCI-NEWS.COM · 3 weeks
High levels of BMAA (β-methylamino-L-alanine), a neurotoxin produced by cyanobacterial blooms, and beta-amyloid plaques, a hallmark in human beings of Alzheimer’s disease, have been... more
How nerve cells control misfolded proteins  SCIENCE DAILY · 4 weeks
Researchers have identified a protein complex that marks misfolded proteins, stops them from interacting with other proteins in the cell and directs them towards disposal. They have identified the so-called Linear Ubiquitin Chain Assembly Complex, Lubac... more
Portable mini microscope could improve scientists' ability to study brain disease in living mice  NEWS MEDICAL · 4 weeks
Working with mice, a team of Johns Hopkins Medicine researchers has developed a relatively inexpensive, portable mini microscope that could... more
New short-pulse ultrasound technique enhances drug delivery to brains of mice  NEWS MEDICAL · 4 weeks
Scientists currently use long-wave pulses of ultrasound to deliver drugs, which can cause side effects. These new findings from Imperial on shorter-wave pulses could have implications... more
Stranded dolphins have amyloid plaques in their brains  PHYS.ORG · 4 weeks
Dolphins stranded on the beaches of Florida and Massachusetts show in their brains amyloid plaques, a hallmark in human beings of Alzheimer's disease, together with an environmental toxin produced by cyanobacterial blooms. more
Technique uses well-known dye to watch amyloid plaques in the brain  PHYS.ORG · 4 weeks
While amyloid plaques have long been closely associated with mechanisms driving Alzheimer's disease, visualizing how amyloid proteins assemble continues to prove difficult. The nanometer-sized amyloid fibrils... more
Diabetes treatment may keep dementia, Alzheimer's at bay  SCIENCE DAILY · 4 weeks
A new study comparing people with diabetes, prediabetes and normal blood sugar finds that diabetes, left untreated, could mean a higher likelihood of developing dementia, including Alzheimer's disease. more
Symptomatic pharmacotherapy of elderly people should be regularly monitored  NEWS MEDICAL · 4 weeks
The prevalence of using antidepressants and proton pump inhibitors increases after the diagnosis of Alzheimer’s disease, according to a doctoral dissertation from the University of Eastern Finland. more
States push for caregiver tax credits  NEWS MEDICAL · 4 weeks
Gloria Brown didn't get a good night's sleep. Her husband, Arthur Brown, 79, has Alzheimer's disease and had spent most of the night pacing their bedroom, opening and closing drawers, and putting on and taking off... more
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Key research takeaways from ECCMID 2019
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Dead pig brains bathed in artificial fluid showed signs of cellular life
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Men who have a resting heart rate of 75 bpm are twice as likely to die early
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Deep sea scientist breaks British depth record
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Robots that can sort recycling
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Pacific island cities call for a rethink of climate resilience for the most vulnerable
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Study tests high-tech, non-pharmaceutical way to address ADHD and distractibility
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NASA wants to send a low-cost mission to explore Neptune's moon Triton
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Smart antioxidant-containing polymer responds to body chemistry, environment
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Ensuring 100% Accuracy in Antibody Protein Sequencing
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Spinning new targets for accelerators
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