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Researchers shed new light on molecular pump that ejects anticancer agents
NEWS MEDICAL Sometimes cells resist medication by spitting it back out. Cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs meant to kill them.... 3 hours
Medical News Today: Neurofeedback treatment for insomnia no better than placebo
MNT Neurofeedback has been considered a potential insomnia therapy for decades. However, breaking research finds it to be no more effective than a placebo. 4 hours
Neurofeedback treatment for insomnia no better than placebo
MNT Neurofeedback has been considered a potential insomnia therapy for decades. However, breaking research finds it to be no more effective than a placebo. 4 hours
Tracking the fate and origin of clinically relevant adoptively transferred CD8+ T cells in vivo
Science Magazine Adoptively transferred tumor-specific cells can mediate tumor regression in cancers refractory to conventional therapy. Autologous polyclonal tumor-specific cytotoxic... 11 hours
Differential contribution of APP metabolites to early cognitive deficits in a TgCRND8 mouse model of Alzheimers disease
Science Magazine Alzheimer’s disease (AD) is a neurodegenerative pathology commonly characterized by a progressive and irreversible... 11 hours
Alzheimer's drug prescribed off-label could accelerate cognitive decline for some patients
NEWS MEDICAL Donepezil, a medication that is approved to treat people with Alzheimer's disease, should not be prescribed for people with mild cognitive impairment without a genetic test. 12 hours
New study finds huge problem of multi-drug resistant infections among children
NEWS MEDICAL In a new, first-of-its-kind study, researchers from Case Western Reserve University School of Medicine have found a 700-percent surge in infections caused by bacteria from the Enterobacteriaceae family... 13 hours
New investigational drug may help combat antibiotic-resistant global health threat
NEWS MEDICAL The deadly fungus, Candida auris, which has been found in hospitals, is resistant to entire classes of antimicrobial drugs, limiting treatment options for those infected. 14 hours
Scientists devise novel DNA vaccine approach against important cancer antigen targets
NEWS MEDICAL Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against... 14 hours
New trial examines use of nanotechnology to improve delivery of drugs to HIV patients
NEWS MEDICAL Successful results of a University of Liverpool-led trial that utilised nanotechnology to improve drug therapies for HIV patients has been... 14 hours
New structural studies reveal workings of a molecular pump that ejects cancer drugs
SCIENCE DAILY Sometimes cells spit out things we don't want them to -- like medications. Researchers have determined the three-dimensional structure of a tiny... 16 hours
New nano approach could cut dose of leading HIV treatment in half
SCIENCE DAILY Successful results have utilized nanotechnology to improve drug therapies for HIV patients. 16 hours
New structural studies reveal workings of a molecular pump that ejects cancer drugs
PHYS.ORG Sometimes cells resist medication by spitting it back out. Cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs... 18 hours
Newly discovered gene variants increase risk of anxiety disorders
NEWS MEDICAL Several newly discovered variants of a gene increase the risk of developing anxiety disorders. A research team aims to derive new therapies from this finding which are better tailored to... 20 hours
Researchers find link between low general cognitive ability and elevated risk of not taking statins
NEWS MEDICAL After a heart attack, it is important for patients to take medication that lowers cholesterol levels. In a... 20 hours
Sports massage therapist offers tips to better recognize and prevent common workout injuries
NEWS MEDICAL For many, the start of a new year means the start of a new workout regimen. It is difficult enough to make... 20 hours
Structure of unique amyloid fibrils could lead to discovery of new antibiotics
NEWS MEDICAL The highly pathogenic Staphylococcus aureus bacteria is one of the five most common causes of hospital-acquired infections. In the US alone, approximately 500,000 patients... 20 hours
New image-guided therapy system to aid clinicians in a variety of procedures developed by Philips
NEWS MEDICAL Royal Philips, a leader in health technology, today announced the global launch of Azurion, its next generation image-guided... 20 hours
New risk factors for anxiety disorders
SCIENCE DAILY Several newly discovered variants of a gene increase the risk of developing anxiety disorders. A research team aims to derive new therapies from this finding which are better tailored to the individual patients. 21 hours
New algorithm identifies gene transfers between different bacterial species
PHYS.ORG Gene transfers are particularly common in the antibiotic-resistance genes of Streptococcus pneumoniae bacteria. 22 hours
Discovery of dual role played by PGK1 enzyme may indicate new therapeutic target for brain cancer
NEWS MEDICAL Discovery of a dual role played by the enzyme phosphoglycerate kinase 1 (PGK1) may indicate a new therapeutic... 24 hours
Novel amyloid structure could lead to new types of antibiotics
PHYS.ORG The highly pathogenic Staphylococcus aureus bacteria is one of the five most common causes of hospital-acquired infections. In the US alone, approximately 500,000 patients at hospitals contract a... 1 day
Physician-delivered step count prescription combined with use of pedometer can provide health benefits
NEWS MEDICAL A study from the Research Institute of the McGill University Health Centre shows that physician-delivered step count prescriptions, combined with the use... 1 day
NR could potentially prevent chemotherapy-induced peripheral neuropathy in cancer patients
NEWS MEDICAL A new study in rats suggests that nicotinamide riboside (NR), a form of vitamin B3, may be useful for treating or preventing nerve pain (neuropathy) caused by chemotherapy... 1 day
New test could accelerate development of better treatments for Motor Neuron Disease
NEWS MEDICAL A cutting-edge test developed in South Australia has the potential to expedite the worldwide quest to develop better treatments, or even a cure, for... 1 day
Study reveals promising therapeutic approach that can be beneficial for older melanoma patients
NEWS MEDICAL Scientists at The Wistar Institute have shown that an anti-diabetic drug can inhibit the growth of melanoma in older patients by activating... 1 day
New analysis finds high rates of initial medication non-adherence in chronic treatments
NEWS MEDICAL A new analysis indicates that not obtaining a medication the first time it is prescribed-called initial medication non-adherence-is common among patients within the Catalan... 2 days
New compounds with potent anticancer activity could lessen side effects of oncological treatments
NEWS MEDICAL The Universitat Jaume I, the Spanish Centre for Advanced Scientific Research and the University of Pavia have patented new compounds with potent... 2 days
Bored by physical therapy? Focus on citizen science instead
PHYS.ORG Researchers at the NYU Tandon School of Engineering have devised a method by which patients requiring repetitive rehabilitative exercises, such as those prescribed by physical therapists, can voluntarily contribute to... 2 days
[Perspective] Why tolerance invites resistance
Science Magazine Bacteria use two strategies to avoid being killed by antibiotics: resistance and tolerance. Resistance mechanisms such as destruction of a drug or modification of its target allow bacteria to grow in the presence of antibiotics. Tolerance is a... 2 days
[Antibiotic Resistance] Resistance on a background of tolerance
Science Magazine Bacteria survive antibiotic exposure either because they are quiescent when antibiotics are around in the highest concentrations (i.e., tolerance) or because they acquire active biochemical – [Read More] 2 days
PERK protein opens line of communication between inside and outside of the cell
PHYS.ORG PERK is known to detect protein folding errors in the cell. Researchers at the Laboratory of Cell Death Research & Therapy at... 2 days
Anti-aging gene identified as a promising therapeutic target for older melanoma patients
SCIENCE DAILY An anti-diabetic drug can inhibit the growth of melanoma in older patients by activating an anti-aging gene that in turn inhibits a protein involved... 2 days
Compounds that show potent anti-cancer activity in breast and colon tumor cell lines
SCIENCE DAILY Potential drugs have shown low toxicity in non-tumor cell lines, which could decrease side effects during chemotherapy, researchers suggest. 2 days
A prescription with legs
SCIENCE DAILY Physician-delivered step count prescriptions, combined with the use of a pedometer, can lead to a 20 per cent increase in daily steps, as well as measurable health benefits, such as lower blood sugar and lower insulin resistance, for patients with... 2 days
Link between aging, devastating lung disease discovered
SCIENCE DAILY A new study has shown evidence linking the biology of aging with idiopathic pulmonary fibrosis, a disease that impairs lung function and causes shortness of breath, fatigue, declining quality of life, and, ultimately, death.... 2 days
Study finds resistant infections rising, with longer hospital stays for US children
SCIENCE DAILY Infections caused by a type of bacteria resistant to multiple antibiotics are occurring more frequently in US children and are associated with longer hospital... 2 days
Researchers Find Antimicrobial Substances in Komodo Dragon Blood
SCI-NEWS.COM A team of researchers at the College of Science at George Mason University has detected 48 antimicrobial peptides in the... 2 days
Scientists propose potential new treatment for Gaucher disease
NEWS MEDICAL Scientists propose in Nature blocking a molecule that drives inflammation and organ damage in Gaucher and maybe other lysosomal storage diseases as a possible treatment with fewer risks and lower costs than... 2 days
New tool to measure patients' muscles could help predict chemotherapy side effects
NEWS MEDICAL Chemotherapy has long been standard treatment for many cancers, but its clinical benefits can also come with well-documented side effects. Doctors say the challenge... 2 days
Chemists discover cheaper, faster way to identify and test new drugs
NEWS MEDICAL Chemists at the University of Waterloo, SCIEX and Pfizer have discovered a new way to help the pharmaceutical industry identify and test new drugs, which could... 2 days
Study finds biochemical pathway that triggers regrowth of breast cancer stem cells after chemotherapy
NEWS MEDICAL Working with human breast cancer cells and mice, researchers at Johns Hopkins say they have identified a biochemical pathway that... 2 days
Study: Testosterone replacement therapy lowers cardiovascular risk in men with androgen deficiency
NEWS MEDICAL Men who used testosterone replacement therapy to treat symptoms of androgen deficiency had a 33 percent lower risk of cardiovascular events such as heart... 2 days
Estrogen therapy can lead to healthier teeth and gums in postmenopausal women, study suggests
NEWS MEDICAL Estrogen therapy has already been credited with helping women manage an array of menopause-related issues, including reducing hot flashes, improving... 2 days
Penn-led researchers gain better understanding of how T cells support long-lived plasma cells
NEWS MEDICAL If you've ever wondered how a vaccine given decades ago can still protect against infection, you have your plasma cells to thank.... 2 days
Questions remain about the benefits of taking testosterone
SCIENCE-NEWS For men with low testosterone, the pros and cons of taking hormone replacement therapy are mixed. 3 days
Measuring patients' muscles to predict chemotherapy side effects
SCIENCE DAILY Measuring patients' muscle mass and quality could potentially help doctors better identify patients at high risk for toxic side effects that could require hospitalizations, researchers report. 3 days
AIDS vaccine may be ‘functional cure’ for some
Science Magazine Can boosting the immune system allow people to toss their anti-HIV drugs? 3 days
Study suggests new therapy for Gaucher disease
SCIENCE DAILY Scientists propose that blocking a molecule that drives inflammation and organ damage in Gaucher, and maybe other lysosomal storage diseases, as a possible treatment with fewer risks and lower costs than current therapies. The... 3 days
[Research Articles] Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2
Science Magazine Trithorax-like group complex containing... 3 days
Study says drugs could be developed cheaper and faster
PHYS.ORG Chemists at the University of Waterloo, SCIEX and Pfizer have discovered a new way to help the pharmaceutical industry identify and test new drugs, which could revolutionize drug development, and... 3 days
Antimicrobial substances identified in Komodo dragon blood
SCIENCE DAILY In a land where survival is precarious, Komodo dragons thrive despite being exposed to scads of bacteria that would kill less hardy creatures. Now in a study, scientists report that they have detected antimicrobial... 3 days
Antimicrobial substances identified in Komodo dragon blood
PHYS.ORG In a land where survival is precarious, Komodo dragons thrive despite being exposed to scads of bacteria that would kill less hardy creatures. Now in a study published in the Journal of Proteome Research,... 3 days
Hormonal maintenance therapy may improve survival in women with chemo-resistant rare ovarian or peritoneum cancer
SCIENCE DAILY For women with a rare subtype of epithelial ovarian or peritoneum cancer, known as low-grade serous carcinoma (LGSC),... 3 days
T cells support long-lived antibody-producing cells, team finds
SCIENCE DAILY A group of researchers has come to a better understanding of how long-lived, antibody-producing plasma cells are maintained. 3 days
Scientists identify chain reaction that shields breast cancer stem cells from chemotherapy
SCIENCE DAILY Working with human breast cancer cells and mice, researchers say they have identified a biochemical pathway that triggers the regrowth of breast cancer stem... 3 days
Estrogen therapy shown effective in reducing tooth and gum diseases in postmenopausal women
SCIENCE DAILY Estrogen therapy has already been credited with helping women manage an array of menopause-related issues, including reducing hot flashes, improving heart health... 3 days
Image: Fires in southeast United States both wild and prescribed
PHYS.ORG Fires both wild and prescribed dot the landscape of the southeastern portion of the United States. Wildfires are those that occur naturally with lightning strikes or are set... 3 days
Precise inactivation of neural messenger receptor wipes out fear memory in mice
SCIENCE DAILY Research combines antibody precision with toxic oxygen burst to inactivate neural protein and temporarily abolish fear memory in mice. 3 days
New method helps researchers piece together the puzzle of antibiotic resistance
PHYS.ORG Researchers from The University of Queensland's Institute for Molecular Bioscience (IMB) have developed a faster and more accurate method for assembling genomes which could help clinicians... 3 days
Study: Hormonal maintenance therapy may improve survival in women with low-grade serous carcinoma
NEWS MEDICAL For women with a rare subtype of epithelial ovarian or peritoneum cancer, known as low-grade serous carcinoma, hormone maintenance therapy may significantly... 3 days
Treating multiple myeloma with rabbit virus eliminates majority of malignant cells, study shows
NEWS MEDICAL Treating multiple myeloma (MM) with myxoma virus (MYXV) eliminated a majority of malignant cells in preclinical studies, report investigators at the Medical... 3 days
'Alarming' superbugs a risk to people, animals and food, EU warns
REUTERS LONDON (Reuters) - Superbug bacteria found in people, animals and food across the European... 3 days
Bayer says Monsanto deal on track, eyes record 2017
PHYS.ORG German pharmaceuticals and chemicals giant Bayer on Wednesday reported record sales and profits for 2016 and said it expected further growth in 2017, as its goal to seal a mammoth... 3 days
Research on repair of broken hearts hints at possibility of new designer cardiovascular therapies
NEWS MEDICAL Unlike the self-repair abilities of our skin, bone and other tissues, which can readily heal and rebuild themselves after injury,... 3 days
Penn expert suggests shorter radiation treatment for men with prostate cancer
NEWS MEDICAL Men with prostate cancer can receive shorter courses of radiation therapy than what is currently considered standard, according to Justin Bekelman, MD, an associate professor of... 3 days
Long-term outcomes following stem cell transplant for multiple sclerosis
SCIENCE DAILY A new study examines the long-term outcomes of patients with aggressive forms of multiple sclerosis (MS) who failed to respond to standard therapies and who underwent autologous hematopoietic stem cell... 4 days
Drugs that alter inhibitory targets offer therapeutic strategies for Autism, Schizophrenia
SCIENCE DAILY Memories are formed at structures in the brain known as dendritic spines, which communicate with other brain cells through 'synapses.' Researchers recently discovered that an inhibitory... 4 days
Chemists reveal novel biocatalysts for bioactive alkaloid synthesis
SCIENCE DAILY Alkaloids are natural nitrogen-containing compounds produced by plants and microbes. These molecules, such as morphine and quinine, are important human medicines. Alkaloids are typically polycyclic in nature. While the polycyclic characteristics are... 4 days
Chemists reveal novel biocatalysts for bioactive alkaloid synthesis
PHYS.ORG Alkaloids are natural nitrogen-containing compounds produced by plants and microbes. These molecules, such as morphine and quinine, are important human medicines. Alkaloids are typically polycyclic in nature. While the polycyclic characteristics are... 4 days
Medical News Today: What are the benefits and risks of testosterone therapy? Studies investigate
MNT Five studies documenting the health effects of testosterone replacement therapy suggest the hormone improves bone density, but it may pose... 4 days
Expert calls for shorter radiation use in prostate cancer treatment
SCIENCE DAILY Men with prostate cancer can receive shorter courses of radiation therapy than what is currently considered standard, according to scientists. 4 days
Scientists identify novel mutations in bacteria that promote evolution of antibiotic resistance
NEWS MEDICAL Scientists from the Broad Institute of MIT and Harvard in Cambridge, Massachusetts, have identified novel mutations in bacteria that promote the evolution of high-level... 4 days
Genetic mutations that drive antibiotic resistance in bacteria
SCIENCE DAILY Scientists have identified novel mutations in bacteria that promote the evolution of high-level antibiotic resistance. 4 days
New behavioral therapy to support Japanese mothers of children with ADHD
SCIENCE DAILY Researchers have successfully adapted a parent-training program for ADHD for use with families in Japan, where ADHD-specific behavioral interventions are limited. 4 days
New range of antibodies released by Cambridge Research Biochemicals®
NEWS MEDICAL Cambridge Research Biochemicals® (CRB), a longstanding British company specialising in the synthesis of custom peptides and the generation of bespoke antibodies for pharmaceutical and medical research, today announced the release... 4 days
Scientists find genetic mutations that drive antibiotic resistance
PHYS.ORG Scientists from the Broad Institute of MIT and Harvard in Cambridge, Massachusetts, have identified novel mutations in bacteria that promote the evolution of high-level antibiotic resistance. 4 days
A novel principle to mobilize neurons for brain repair
SCIENCE DAILY Restorative neuroscience is a rapidly advancing scientific field considering our progressively aging society. Redirecting immature neurons that reside in specific brain areas towards the sites of brain damage is an... 4 days
Many cancer survivors change their prescription drug use for financial reasons
SCIENCE DAILY A new analysis indicates that many cancer survivors change their prescription drug use (including skipping doses or requesting cheaper medications) for financial reasons. 4 days
New nano approach could cut dose of leading HIV treatment in half
PHYS.ORG Successful results of a University of Liverpool-led trial that utilised nanotechnology to improve drug therapies for HIV patients has been presented at the Conference... 4 days
rapid patient recruitment and reduced trial costs is lds the answer Rapid patient recruitment and reduced trial costs: is LDS the answer?
NEWS MEDICAL VIDEO LDS stands for Linked Database System, which essentially describes what it does. Our LDS technology uses multiple sources of information from hospitals, GPs and pharmacies. However... 4 days
Clarkson University research on walking ability shows new way to recovery for stroke survivors
NEWS MEDICAL Stroke is the leading cause of disability in older adults in the United States, but research by Clarkson University Associate... 4 days
RCSI research focuses on need to personalise treatment for bowel cancer patients
NEWS MEDICAL Researchers in RCSI (Royal College of Surgeons in Ireland) have conducted further in-depth research to predict how patients with bowel (colorectal) cancer will respond... 4 days
Non-elderly cancer survivors more likely to change prescription drug use for financial reasons, study finds
NEWS MEDICAL A new analysis indicates that many cancer survivors change their prescription drug use (including skipping doses or requesting... 4 days
Neonatal sepsis risk calculator reduces antibiotic use by nearly 50% in newborns
NEWS MEDICAL Kaiser Permanente, the largest integrated health system in the nation, led the development of a neonatal sepsis risk calculator that has safely reduced antibiotic... 4 days
New study examines long-term outcomes for MS patients after stem cell transplantation
NEWS MEDICAL A new study published online by JAMA Neurology examines the long-term outcomes of patients with aggressive forms of multiple sclerosis (MS) who failed to... 4 days
On the Knife's Edge: Using Therapy To Address Violence Among Teens
NPR We hear a lot about senseless violence: people who lose their lives or their freedom over a stolen backpack, or perceived slight. Two researchers think social... 4 days
Majority of parents with children at home don't lock up prescribed opioids, study finds
ABC NEWS Opioid use has soared in the U.S. in recent years. 5 days
Medical News Today: Appendicitis: Antibiotics could be alternative to surgery for children
MNT Evidence review shows antibiotics could be a safe alternative to surgery in children with appendicitis and calls for large randomized trials to confirm it. 5 days
Majority of opioid medications not safely stored in homes with children, survey finds
SCIENCE DAILY Nearly 70 percent of prescription opioid medications kept in homes with children are not stored safely, a new study finds. 5 days
Virus inspires new way to deliver cancer drugs
PHYS.ORG Drugs disguised as viruses are providing new weapons in the battle against cancer, promising greater accuracy and fewer side effects than chemotherapy. 5 days
Detrimental impact of iron deficiency made aware by Vifor Pharma at a series of events
NEWS MEDICAL The 12th ECCO Congress that took place in Barcelona, Spain, from 15 to 18 February 2017, was an... 5 days
Study shines light on pervasiveness of unsafely stored opioids in homes with children
NEWS MEDICAL Nearly 70 percent of prescription opioid medications kept in homes with children are not stored safely, a new study by researchers at... 5 days
Antibiotics could be alternative to surgery as treatment for appendicitis
MNT A study by researchers at the University of Southampton shows that antibiotics may be an effective treatment for acute non-complicated appendicitis in children, instead of surgery. 5 days
Penn researchers find new way to track rare T cells in blood after annual flu vaccine
NEWS MEDICAL For most vaccines to work the body needs two cell types - B cells and T... 5 days
New approach could make organometallic catalysis applicable for therapy or diagnostics
NEWS MEDICAL A gold catalyst can be delivered to a target organ in a higher organism where it performs a chemical transformation visualized by bioimaging. 7 days
Disappointing Merck drug news provides new blueprint for moving towards cure for Alzheimer's
NEWS MEDICAL The recent announcement that Merck is halting a Phase II/III study for a promising Alzheimer's treatment (verubecestat) was another setback in the continued and... 7 days
Rapid patient recruitment and reduced trial costs: is LDS the answer?
NEWS MEDICAL
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