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SCIENCE DAILY Scientists have performed the first all-atom molecular dynamics simulations of Cas9-catalyzed DNA cleavage in action. The simulations shed light on the process of Cas9 genome editing and helped resolve controversies about specific aspects of the cutting. 1 month
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IBS scientists modify fat content in soybean oil using new CRISPR-Cpf1 technology
NEWS MEDICAL A team from the Center for Genome Engineering, within the Institute for Basic Research (IBS), succeeded in editing two genes that contribute to the... 5 days
[Feature] The Birth of CRISPR Inc
Science Magazine Just 5 years ago, the community of researchers studying CRISPR, the powerful new genome editing tool, was small. When the first inklings that CRISPR could become a big business emerged, leading scientists expected to work together.... 5 days
Modifying fat content in soybean oil with the molecular scissors Cpf1
PHYS.ORG A team from the Center for Genome Engineering, within the Institute for Basic Research (IBS), succeeded in editing two genes that contribute to the fat contents... 5 days
Round one of CRISPR patent legal battle goes to the Broad Institute
Science Magazine Patent board finds Broad's patent on genome-editing method distinct from claims by University of California 6 days
Genome surgery with CRISPR-Cas9 to prevent blindness
SCIENCE DAILY CRISPR-Cas9 can be delivered directly into the eye of living animals to treat age-related macular degeneration efficiently and safely, report scientists. 5 days
With stringent oversight, heritable human genome editing could be allowed
SCIENCE DAILY Clinical trials for genome editing of the human germline -- adding, removing, or replacing DNA base pairs in gametes or early embryos -- could be permitted in the... 6 days
What's holding up CRISPR-based cures
PHYS.ORG The gene-editing tool called CRISPR that can quickly and cleanly remove specific pieces of DNA has revolutionized biotechnology. Many researchers believe the technique could end thousands of ailments. So what's needed to realize CRISPR's potential? Another breakthrough. The... 6 days
Moonshot pad roaring back into action with SpaceX launch
PHYS.ORG The launch pad used to send Americans to the moon and shuttle astronauts into orbit is roaring back into action. 4 days
[Policy Forum] CRISPR, surrogate licensing, and scientific discovery
Science Magazine Several institutions are embroiled in a legal dispute over the foundational patent rights to CRISPR-Cas9 gene-editing technology, and it may take years for their competing claims to be resolved (1–4). But even... 5 days
How the battle lines over CRISPR were drawn
Science Magazine Commercializing the revolutionary gene-editing tool led to acrimonious disputes over intellectual property, academic credit, and personal profit 6 days
GBSI reports encouraging progress toward improved research reproducibility by year 2020
PHYS.ORG One year after the Global Biological Standards Institute (GBSI) issued its Reproducibility2020 challenge and action plan for the biomedical research community, the organization reports encouraging progress... 2 days
UNIGE researchers develop new technique to improve diagnosis of genetic diseases
NEWS MEDICAL When a child is conceived, he or she receives DNA from both parents. The child's own genome thus consists of a maternal and a paternal genome.... 5 days
Early warning system flags global financial crises
SCIENCE DAILY Researchers have developed a new 'early warning system' that could help policymakers around the world take action to avert or lessen the impact of financial crisis. 6 days
Human gene editing therapies are OK in certain cases, panel advises
SCIENCE-NEWS A panel of experts says clinical gene editing to correct and prevent human disease should move forward, but enhancements should not be allowed. 6 days
Micro-RNA may amplify effectiveness of sorafenib in difficult liver cancer cases
SCIENCE DAILY Only 25% of patients respond to sorafenib treatment, so researchers have endeavored to understand its mechanism of action and discover a way to boost its effectiveness. 2 days
Gene editing can complement traditional food-animal improvements
PHYS.ORG Gene editing—one of the newest and most promising tools of biotechnology—enables animal breeders to make beneficial genetic changes, without bringing along unwanted genetic changes. 3 days
Gene editing mulled for improving livestock
PHYS.ORG Gene editing, which has raised ethical concerns due to its capacity to alter human DNA, is being considered in the United States as a tool for improving livestock, experts say. 3 hours
Gene editing patent ruling sways fortune of biotech hopefuls
PHYS.ORG In a highly anticipated decision that could sway the fortunes of a handful of biotechnology companies, the federal patent office has turned back a challenge to patents covering a widely... 5 days
Historic Cape Canaveral launchpad returns to action with SpaceX
REUTERS CAPE CANAVERAL, Fla. (Reuters) - The seaside Florida launchpad from which astronauts once blasted off for the moon... 4 days
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