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Unravelling the mystery of DNA attacks in cells' powerhouse could pave way for new cancer treatments
SCIENCE DAILY A five-year study has found the mechanism responsible for repairing damage to mitochondrial DNA. This discovery... 4 hours
The ocean detectives
SCIENCE DAILY Three new groups of viruses that attack microorganisms from the archaeal marine group, Euryarchaeota have been discovered by scientists. In all, 26 viruses previously unknown to science were found. 4 hours
German scientists unravel defense strategy of mushrooms against insect larvae
NEWS MEDICAL Some mushrooms produce long-chain unsaturated carboxylic acids as their chemical defense against insect larvae. The biosynthesis of these polyenes relies on only one enzyme, as German scientists have... 5 hours
Actress Kiruna Stamell argues about gene editing with Dr Christopher Gyngell
NEWS MEDICAL Two papers published today by the Journal of the Royal Society of Medicine, debate gene editing and the health of future generations. 5 hours
Medical News Today: One-shot osteoarthritis drug investigated
MNT A new drug that clears up old cells in the joints might one day offer a one-shot cure for osteoarthritis. Early trials yield promising results. 9 hours
China creates new kinase-based whole-cell screening library for high-throughput drug assay
NEWS MEDICAL After five years of hard work, China has completed the world's largest kinase-based whole-cell screening library for high-throughput drug assay. 15 hours
Study sheds new light on evolutionary origin of the vertebrate brain
NEWS MEDICAL A study recently published in PLOS Biology provides information that substantially changes the prevailing idea about the brain formation process in vertebrates and sheds some light... 17 hours
Researchers explore link between gut microbiome and nutrition in autism spectrum disorder
NEWS MEDICAL Over the last decade, research has revealed more about the human gut microbiome—the environment within the gastrointestinal tract—where microbes, especially bacteria, reside. Recently, more... 17 hours
FDA approves new drug and chemotherapy combination for treatment of adult patients with AML
NEWS MEDICAL The U.S. Food and Drug Administration today approved Rydapt (midostaurin) for the treatment of adult patients with newly diagnosed acute... 17 hours
Penn State establishes new $2.4-million Biomedical Big Data to Knowledge Training Program
NEWS MEDICAL A new $2.4-million program for graduate students seeking to contribute to breakthrough discoveries in medicine and biology has been established at Penn State University with nearly... 18 hours
Human vaccine data release jump-starts biotech’s bid for RNA drugs
Science Magazine Moderna, a biotech valued at more than a $1 billion despite not having any approved products, finally publishes its first human trial data 21 hours
Human vaccine data release jumpstarts biotech’s bid for RNA drugs
Science Magazine Moderna, a biotech valued at more than a $1 billion despite not having any approved products, finally publishes its first human trial data 22 hours
Lungs enlist immune cells to fight infections in capillaries
SCIENCE-NEWS Immune cells in the lungs provide a rapid counterattack to bloodstream infections, a new study in mice finds. 22 hours
Researchers find persistence of Zika virus in cerebrospinal fluid, lymph nodes of rhesus monkeys
NEWS MEDICAL Zika virus can persist in cerebrospinal fluid (CSF), lymph nodes and colorectal tissue of infected rhesus monkeys for weeks after the virus... 22 hours
Discovery of a facile process for H2 production using ammonia as a carrier
PHYS.ORG Hydrogen (H2) has attracted considerable attention as a clean energy source because the only by-product of its reaction with oxygen is water,... 23 hours
The lung is a host defense niche for immediate neutrophil-mediated vascular protection
Science Magazine Bloodstream infection is a hallmark of sepsis, a medically emergent condition requiring rapid treatment. However, up-regulation of host defense proteins through Toll-like receptors (TLRs)... 23 hours
Complement factor P is a ligand for the natural killer cell-activating receptor NKp46
Science Magazine Innate lymphoid cells (ILCs) are involved in immune responses to microbes and various stressed cells, such as tumor cells. They include group... 23 hours
Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage
Science Magazine Breakage of one strand of DNA is the most common form of DNA damage. Most damaged DNA termini require end-processing... 23 hours
Crystal structure of 2C helicase from enterovirus 71
Science Magazine Enterovirus 71 (EV71) is the major pathogen responsible for outbreaks of hand, foot, and mouth disease. EV71 nonstructural protein 2C participates in many critical events throughout the virus life cycle; however, its... 23 hours
Genuine binding energy of the hydrated electron
Science Magazine The unknown influence of inelastic and elastic scattering of slow electrons in water has made it difficult to clarify the role of the solvated electron in radiation chemistry and biology. We combine accurate scattering... 23 hours
Plague bacteria take refuge in amoebae
PHYS.ORG Yersinia pestis, the bacterium that causes bubonic plague, can survive within the ubiquitous soil protozoan, the amoeba, by producing proteins that protect against the latter microbe's digestion. The research is published April 28th in Applied and... 23 hours
Plague bacteria take refuge in amoebae
SCIENCE DAILY Yersinia pestis, the bacterium that causes bubonic plague, can survive within the ubiquitous soil protozoan, the amoeba, by producing proteins that protect against the latter microbe's digestion, report scientists. 23 hours
Success in the 3-D bioprinting of cartilage
SCIENCE DAILY A team of researchers has managed to generate cartilage tissue by printing stem cells using a 3-D-bioprinter. The fact that the stem cells survived being printed in this manner is a success in itself.... 23 hours
Nerve cell miswiring linked to depression
SCIENCE-NEWS A gene helps nerve cell axons extend to parts of the brain to deliver serotonin, a brain chemical associated with depression. 23 hours
Ocean acidification may hamper food web’s nitrogen-fixing heroes
SCIENCE-NEWS A new look at marine Trichodesmium microbes suggests trouble for nitrogen fixation in an acidifying ocean. 24 hours
Gene critical for tumor progression also encourages growth of intestinal stem cells, study shows
NEWS MEDICAL A gene previously identified as critical for tumor growth in many human cancers also maintains intestinal stem cells and encourages... 1 day
Zika virus persists in the central nervous system and lymph nodes of rhesus monkeys
SCIENCE DAILY Zika virus can persist in cerebrospinal fluid (CSF), lymph nodes and colorectal tissue of infected rhesus monkeys for weeks after... 1 day
Denisovan and Neanderthal DNA Uncovered in Caves without Skeletal Remains
SCI-NEWS.COM New research led by the Max Planck Institute for Evolutionary Anthropology (MPI-EVA) shows that Pleistocene cave... 1 day
Unlikely pair of plants named after stars of movie 'twins'
SCIENCE DAILY Biologists have named an unlikely pair of plants after Arnold Schwarzenegger and Danny DeVito, the stars of the 1988 movie Twins. 1 day
unlikely pair of plants named after stars of movie twins Unlikely pair of plants named after stars of movie 'Twins'
PHYS.ORG VIDEO Biologists from The Australian National University (ANU) have named an unlikely pair of plants after Arnold Schwarzenegger and Danny DeVito, the stars of the 1988 movie Twins. 1 day
New study revises the development and evolutionary origin of the vertebrate brain
PHYS.ORG A study recently published in PLOS Biology provides information that substantially changes the prevailing idea about the brain formation process in vertebrates and sheds... 1 day
Mining: Bacteria with Midas touch for efficient gold processing
SCIENCE DAILY Special 'nugget-producing' bacteria may hold the key to more efficient processing of gold ore, mine tailings and recycled electronics, as well as aid in exploration for new deposits, research has... 1 day
Gene critical for tumor growth also encourages growth of intestinal stem cells, study shows
NEWS MEDICAL A gene previously identified as critical for tumor growth in many human cancers also maintains intestinal stem cells and encourages... 1 day
Symbiotic bacteria: From hitchhiker to beetle bodyguard
SCIENCE DAILY Bacterial symbionts transition between plant pathogenicity and insect defensive mutualism, a new report demonstrates. The bacterium Burkholderia gladioli lives in specific organs of a plant-feeding beetle and defends the insect's eggs from detrimental fungi... 1 day
Bacterial symbionts transition between plant pathogenicity and insect defensive mutualism
PHYS.ORG An international team of researchers have discovered a remarkable microbe with a Jekyll and Hyde character. The bacterium Burkholderia gladioli lives in specific organs of a plant-feeding beetle... 1 day
We are more than our DNA: Discovering a new mechanism of epigenetic inheritance
SCIENCE DAILY The existence of transgenerational epigenetic inheritance has now been demonstrated among Drosophila fruit flies. By temporarily modifying the function of Polycomb Group... 1 day
Ocean acidification could impair the nitrogen-fixing ability of marine bacteria
SCIENCE DAILY While increased carbon dioxide levels theoretically boost the productivity of nitrogen-fixing bacteria in the world's oceans, because of its 'fertilizing' effect, a new study reveals how increasingly acidic... 1 day
Single gene encourages growth of intestinal stem cells, supporting 'niche' cells, and cancer
SCIENCE DAILY A gene previously identified as critical for tumor growth in many human cancers also maintains intestinal stem cells and encourages the growth... 1 day
Efficient catalyst developed for producing pronucleotides
PHYS.ORG (Phys.org)—A team of researchers with Merck & Co., Inc. has developed an efficient catalyst for producing pronucleotides, paving the way perhaps to a new class of drugs for combatting viruses and cancer. In their paper published... 1 day
Send Your DNA to Space and Back via New Service
SPACE.COM Celestis, the same company that lets people send their loved ones' cremated remains to space, unveiled a new service that will launch samples of DNA off the planet. 1 day
Compact fibre optic apparatus shines light on breath analysis in real-time
PHYS.ORG Using hollow-core optical fibre as a sensitive gas cell, researchers in Japan have devised a relatively simple and affordable sensor for monitoring biomarkers in human breath... 1 day
The role of microorganisms in industrial gold processing
PHYS.ORG Special 'nugget-producing' bacteria may hold the key to more efficient processing of gold ore, mine tailings and recycled electronics, as well as aid in exploration for new deposits, University of Adelaide research... 1 day
Cassava is genetically decaying, putting staple crop at risk
PHYS.ORG For breeders of cassava, a staple food for hundreds of millions in the tropics, producing improved varieties has been getting harder over time. A team at Cornell used genomic analysis... 1 day
How plants form their sugar transport routes
PHYS.ORG In experiments on transport tissues in plants, researchers from Heidelberg University were able to identify factors of crucial importance for the formation of the plant tissue known as phloem. According to Prof. Dr Thomas... 1 day
Researchers succeed in generating 3D bioprinted cartilage tissue
NEWS MEDICAL A team of researchers at Sahlgrenska Academy has managed to generate cartilage tissue by printing stem cells using a 3D-bioprinter. 1 day
Scientists unravel how protein impacts intellectual disability
MNT Scientists from the Florida campus of The Scripps Research Institute (TSRI) have shown that a protein helps balance nerve cell communication. 1 day
Gut bacteria tell the brain what animals should eat
MNT Neuroscientists have, for the first time, shown that gut bacteria "speak" to the brain to control food choices in animals. 1 day
Chronic fatigue syndrome linked to imbalanced microbiome
MNT Scientists at the Center for Infection and Immunity (CII) at Columbia University's Mailman School of Public Health have discovered abnormal levels of specific gut bacteria related to chronic... 1 day
Scientists rewire mouse stem cells to fight inflammation caused by arthritis
NEWS MEDICAL Using new gene-editing technology, researchers have rewired mouse stem cells to fight inflammation caused by arthritis and other chronic conditions. 1 day
Researchers show resident T cells in the skin depend on CD103 molecule for their anti-tumor function
NEWS MEDICAL The molecule CD103 is key to the long-term residence of T cells in the skin and... 1 day
Growing mouse tooth provides new understanding of tissue renewal processes
NEWS MEDICAL Researchers hope to one day use stem cells to heal burns, patch damaged heart tissue, even grow kidneys and other transplantable organs from scratch. 1 day
Protein 'spy' gains new abilities
SCIENCE DAILY A method to rapidly trigger the universal tagging of proteins being produced by a cell has now been discovered by researchers. The tagging can be turned on like a switch, which enables researchers to acquire a snapshot of... 2 days
Study quantifies kidney failure risk in living kidney donors
SCIENCE DAILY Researchers have developed a risk calculator that estimates the risk of kidney failure after donation. Overall risk was low, but black race and male sex were associated with increased risks... 2 days
Scientists use rooster testes to shed light on how germ cells fight viruses
NEWS MEDICAL Our bodies are constantly under siege by foreign invaders; viruses, bacteria and parasites that want to infiltrate our cells. 2 days
Neurons' faulty wiring leads to serotonin imbalance, depression-like behavior in mice
SCIENCE DAILY A gene has been identified that allows neurons that release serotonin to evenly spread their branches throughout the brain. Without this gene, these branches become entangled,... 2 days
Stem cells edited to fight arthritis
SCIENCE DAILY Using CRISPR technology, a team of researchers rewired stem cells' genetic circuits to produce an anti-inflammatory arthritis drug when the cells encounter inflammation. The technique eventually could act as a vaccine for arthritis and other chronic... 2 days
Mouse teeth providing new insights into tissue regeneration
SCIENCE DAILY Researchers hope to one day use stem cells to heal burns, patch damaged heart tissue, even grow kidneys and other transplantable organs from scratch. 2 days
Your Brain Waves May Show Whether You're Paying Attention in Class
LIVE SCIENCE You really can get on the same wavelength as someone else: In a new study, the brain waves of high school students synced up when they... 2 days
How plants form their sugar transport routes
SCIENCE DAILY In experiments on transport tissues in plants, researchers were able to identify factors of crucial importance for the formation of the plant tissue known as phloem. These factors differ from all previously known factors... 2 days
$10 million settlement over alleged misconduct in Boston heart stem cell lab
Science Magazine Brigham and Women’s Hospital to pay government after probe of manipulated and fabricated data 2 days
WATCH: Exercise can help offset effects of 'fat gene,' study finds
ABC NEWS A new study sheds light on how people can counteract their genetic makeup, even if it's in their DNA to put on more weight than others. 2 days
Exercise can help offset effects of 'fat gene,' study finds
ABC NEWS The study's authors looked at how lifestyle and genes affects weight gain. 2 days
Podcast: Where dog breeds come from, bots that build buildings, and gathering ancient human DNA from cave sediments
Science Magazine This week, a new family tree of dog breeds, advances in artificial... 2 days
Researchers build a novel switch to facilitate tagging of proteins in a cell
PHYS.ORG Rice University scientists have learned to spy on cells with a divide-and-conquer strategy to label proteins. 2 days
Resource availability drives person-to-person variations in microbes living in the body
SCIENCE DAILY The collection of microbial species found in the human body varies from person to person, and new research suggests that a significant part of this variation... 2 days
Cystic fibrosis: Interactions between bacteria that infect lungs uncovered
SCIENCE DAILY Substances produced by a harmful bacterium in the lungs of cystic fibrosis patients may enhance the growth of other bacteria that, in turn, inhibit the harmful bacterium's biofilm, according to... 2 days
Chemoresistance in breast cancer is related to varying tumor cell populations
SCIENCE DAILY Scientists have recreated and characterized the process of acquisition of resistance to chemotherapy in orthotopic animal models of breast cancer, unveiling the possibility of reversing this... 2 days
This new battery could save your cellphone from going up in smoke
Science Magazine Zinc-nickel rechargeables would be safer and cheaper than lithium-ion cells 2 days
DNA from extinct humans discovered in cave sediments
SCIENCE DAILY Researchers have developed a new method to retrieve hominin DNA from cave sediments -- even in the absence of skeletal remains. 2 days
Physical activity helps to counteract weight gain from obesity-causing gene variant
SCIENCE DAILY Physical activity can reduce the weight-gaining effects of the genetic variant that carries the greatest risk of obesity, report. 2 days
Tibetan people have multiple adaptations for life at high altitudes
SCIENCE DAILY The Tibetan people have inherited variants of five different genes that help them live at high altitudes, with one gene originating in the extinct human subspecies, the Denisovans. 2 days
No bones? No problem: DNA left in cave soils can reveal ancient human occupants
Science Magazine Technique can trace Neandertals, Denisovans without fossils 2 days
This new battery could save your cell phone from going up in smoke
Science Magazine Zinc–nickel rechargeables would be safer and cheaper than lithium-ion cells 2 days
A quarter of nursing home residents are colonized with drug-resistant bacteria
SCIENCE DAILY The significant presence of multidrug-resistant gram-negative bacteria (MDR-GNB), such as E. coli, among nursing home residents demonstrates the need for heightened infection control prevention and control... 2 days
DNA from extinct humans discovered in cave sediments
PHYS.ORG Researchers have developed a new method to retrieve hominin DNA from cave sediments—even in the absence of skeletal remains. 2 days
Resource availability drives person-to-person variations in microbes living in the body
PHYS.ORG The collection of microbial species found in the human body varies from person to person, and new research published in PLOS Computational Biology suggests that a... 2 days
Long After Their Bones Were Gone, Neanderthals' DNA Survived in a Cave
LIVE SCIENCE DNA from Neanderthals and a mysterious branch of humanity called Denisovans has been detected in the ancient mud of caves holding no fossilized remains... 2 days
Photos: Looking for Extinct Humans in Ancient Cave Mud
LIVE SCIENCE Scientists have discovered DNA from extinct human lineages in caves devoid of skeletal remains. Here's a look at the archaeological sites and the sample collection. 2 days
Computational research details the activation mechanism of p38?
SCIENCE DAILY p38? is a protein involved in chronic inflammatory diseases and cancer, among other pathological conditions. A new study provides a deeper understanding of the structure of this protein, thereby paving the way... 2 days
Ancient DNA bucks tale of how the horse was tamed
SCIENCE-NEWS DNA from ancient horses reveals early domestication involved plenty of stallions. 2 days
Fecal microbiota transplant may be effective treatment option for ulcerative colitis, research suggests
NEWS MEDICAL A single transplant of microbes contained in the stool of a healthy donor is a safe and effective way to increase diversity of good... 2 days
Scientists Find Link between Immune System, Memory and Structure of Brain
SCI-NEWS.COM In two separate studies, researchers have demonstrated that both the structure of the brain... 2 days
Neandertal and Denisovan DNA from Pleistocene sediments
Science Magazine Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA we show that... 2 days
Rechargeable nickel-3D zinc batteries: An energy-dense, safer alternative to lithium-ion
Science Magazine The next generation of high-performance batteries should include alternative chemistries that are inherently safer to operate than nonaqueous lithium-based batteries. Aqueous zinc-based batteries can answer that challenge because... 2 days
Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15
Science Magazine Indisulam is an aryl sulfonamide drug with selective anticancer activity. Its mechanism of action and the basis for its selectivity have so far been... 2 days
Pcdh{alpha}c2 is required for axonal tiling and assembly of serotonergic circuitries in mice
Science Magazine Serotonergic neurons project their axons pervasively throughout the brain and innervate various target fields in a space-filling manner, leading to tiled arrangements... 2 days
Germ cells on demand
Science Magazine 2 days
Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network
Science Magazine Neuropsychiatric disorders have a complex genetic architecture. Human genetic population-based studies have identified numerous heritable sequence and structural genomic variants associated with... 2 days
RETINOBLASTOMA RELATED1 mediates germline entry in Arabidopsis
Science Magazine To produce seeds, flowering plants need to specify somatic cells to undergo meiosis. Here, we reveal a regulatory cascade that controls the entry into meiosis starting with a group of redundantly acting cyclin-dependent kinase... 2 days
Multicluster Pcdh diversity is required for mouse olfactory neural circuit assembly
Science Magazine The vertebrate clustered protocadherin (Pcdh) cell surface proteins are encoded by three closely linked gene clusters (Pcdhα, Pcdhβ, and Pcdh). Here, we show that all three... 2 days
Linking stem cells to germ cells
Science Magazine 2 days
Ancient genomic changes associated with domestication of the horse
Science Magazine The genomic changes underlying both early and late stages of horse domestication remain largely unknown. We examined the genomes of 14 early domestic horses from the Bronze and Iron Ages,... 2 days
Single-cell diversity in the brain
Science Magazine 2 days
Extracting the contents of living cells
Science Magazine 2 days
Study finds significant presence of multidrug-resistant bacteria among nursing home residents
NEWS MEDICAL The significant presence of multidrug-resistant gram-negative bacteria, such as E. coli, among nursing home residents demonstrates the need for heightened infection control prevention and control measures... 2 days
Molecule identified that helps give resident T cells in the skin their anti-cancer punch
SCIENCE DAILY The molecule CD103 is key to the long-term residence of T cells in the skin and to their anti-tumor function,... 2 days
Using rooster testes to learn how the body fights viruses
SCIENCE DAILY Our bodies are constantly under siege by foreign invaders; viruses, bacteria and parasites that want to infiltrate our cells. Using rooster testes, scientists shed light on how germ... 2 days
Unlikely pair of plants named after stars of movie 'Twins'
PHYS.ORG
Student's Genes in Space Test Looks at Effects of Microgravity on Chromosomes
SPACE.COM
Sequencing the station: Investigation aims to identify unknown microbes in space
PHYS.ORG
Bio-prospecting for better enzymes
PHYS.ORG