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can bacteria survive in mars soil and thus enhance crop production Can Bacteria Survive in Mars Soil and Thus Enhance Crop Production?
ASTRO WATCH The Imperial College in London is going to investigate if bacteria will survive in... 8 hours
Dietary prebiotics improve sleep, buffer impacts of stress, says study
SCIENCE DAILY New research suggests that lesser-known gut-health promoters called prebiotics -- which serve as food for good bacteria inside the gut -- can also have an impact, improving sleep... 10 hours
Diving deep into the dolphin genome could benefit human health
SCIENCE DAILY A new database of bottlenose dolphin DNA and associated proteins just completed could possibly aid in dolphin care and research of human medical problems such as stroke and... 10 hours
Antibiotic resistance: A burgeoning problem for kids too
SCIENCE DAILY In a new, first-of-its-kind study, researchers have found a 700-percent surge in infections caused by bacteria from the Enterobacteriaceae family resistant to multiple kinds of antibiotics among children in the US. These... 1 day
Novel 'barcode' tracking of T cells in immunotherapy patients identifies likely cancer-killers
SCIENCE DAILY A new discovery makes an important step in identifying which specific T cells within the diverse army of a person's immune system are best... 1 day
Are Viruses Alive?
LIVE SCIENCE Viruses are infectious, tiny and nasty. But are they alive? 1 day
Decoding the genome's cryptic language
SCIENCE DAILY Bioengineers have developed a new tool to identify RNA-DNA interactions. The tool can provide a full account of all the RNA molecules that interact with a segment of DNA, as well as the locations of all these interactions... 1 day
Researchers shed new light on molecular pump that ejects anticancer agents
NEWS MEDICAL Sometimes cells resist medication by spitting it back out. Cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs meant to kill them.... 2 days
Study finding suggests new ways in which genetic mutations may cause brain disorders
NEWS MEDICAL Many kids say they love their mom and dad equally, but there are times when even the best prefers one parent over... 2 days
Fred Hutch scientists make important step in identifying specific T cells to fight against cancer
NEWS MEDICAL A new discovery by researchers at the Fred Hutchinson Cancer Research Center in Seattle makes an important step... 2 days
The checkpoint for agonist selection precedes conventional selection in human thymus
Science Magazine The thymus plays a central role in self-tolerance, partly by eliminating precursors with a T cell receptor (TCR) that binds strongly to self-antigens. However, the generation... 2 days
Tracking the fate and origin of clinically relevant adoptively transferred CD8+ T cells in vivo
Science Magazine Adoptively transferred tumor-specific cells can mediate tumor regression in cancers refractory to conventional therapy. Autologous polyclonal tumor-specific cytotoxic... 2 days
Mitochondrial metabolic regulation by GRP78
Science Magazine Steroids, essential for mammalian survival, are initiated by cholesterol transport by steroidogenic acute regulatory protein (StAR). Appropriate protein folding is an essential requirement of activity. Endoplasmic reticulum (ER) chaperones assist in folding of cytoplasmic proteins, whereas mitochondrial chaperones... 2 days
MGH researchers discover regulators of gene expression programs in medulloblastoma
NEWS MEDICAL Massachusetts General Hospital researchers have identified a mechanism that controls the expression of genes regulating the growth of the most aggressive form of medulloblastoma, the most common pediatric... 2 days
Pitt study sheds light on shared roots of schizophrenia and rheumatoid arthritis
NEWS MEDICAL An in-depth computational analysis of genetic variants implicated in both schizophrenia and rheumatoid arthritis by researchers at the University of Pittsburgh points to eight... 2 days
Dietary prebiotics can improve sleep after stress exposure, study suggests
NEWS MEDICAL In recent years, reams of research papers have shed light on the health benefits of probiotics, the "good bacteria" found in fermented foods and dietary supplements. 2 days
New study finds huge problem of multi-drug resistant infections among children
NEWS MEDICAL In a new, first-of-its-kind study, researchers from Case Western Reserve University School of Medicine have found a 700-percent surge in infections caused by bacteria from the Enterobacteriaceae family... 2 days
Novel antiviral drug can protect transplant patients against CMV infections
NEWS MEDICAL In a significant advance in improving the safety of donor stem cell transplants, a major clinical trial led by researchers at Dana-Farber Cancer Institute and Brigham and Women's... 2 days
New research pinpoints how bacteria get into lungs of healthy people
NEWS MEDICAL They traveled a huge distance, evaded a protective barrier, and found themselves in a strange and unwelcoming land. 2 days
Scientists devise novel DNA vaccine approach against important cancer antigen targets
NEWS MEDICAL Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against... 2 days
New humanized model enables better characterization of Alzheimer's pathology
NEWS MEDICAL Cells behave differently when removed from their environments, just as cells that develop in cultures do not behave like cells in living creatures. 2 days
New structural studies reveal workings of a molecular pump that ejects cancer drugs
SCIENCE DAILY Sometimes cells spit out things we don't want them to -- like medications. Researchers have determined the three-dimensional structure of a tiny... 2 days
New tool to map RNA-DNA interactions could help researchers translate gene sequences into functions
PHYS.ORG Bioengineers at the University of California San Diego have developed a new tool to identify interactions between RNA and DNA... 2 days
'Doomsday Vault' Gains 50,000 Seeds to Fend Off Food Crises
LIVE SCIENCE The new deposit included samples from gene banks around the world. 2 days
Fasting-mimicking diet may reverse diabetes
SCIENCE DAILY In a study on mice and another study on human pancreatic cells, researchers discover that a scientifically designed fasting diet can trigger the generation of new pancreatic cells to replace dysfunctional ones and stabilize blood glucose. 2 days
Researchers use confined nanoparticles to improve hydrogen storage materials performance
PHYS.ORG Sometimes, you have to go small to win big. That is the approach a multilab, interdisciplinary team took in using nanoparticles and a novel nanoconfinement system to develop... 2 days
Sink Full of Superbugs? Study Finds Surprising Way Germs Spread
LIVE SCIENCE Drug-resistant bacteria can lurk in the pipes of hospital sinks, and a new study shows that these dangerous bacteria can also make their way out of sinks and... 2 days
New structural studies reveal workings of a molecular pump that ejects cancer drugs
PHYS.ORG Sometimes cells resist medication by spitting it back out. Cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs... 2 days
Biologists propose to sequence the DNA of all life on Earth
Science Magazine Still-unfunded plan would start with all plants, animals, and other eukaryotes—some 1.5 million species—for the cost of the original human genome project 2 days
How proteins reshape cell membranes
SCIENCE DAILY Small 'bubbles' frequently form on membranes of cells and are taken up into their interior. The process involves EHD proteins. Scientists have now shed light on how these proteins assemble on the surface of a cell and reshape... 2 days
In enemy garb: New explanation for wasp mimicry
SCIENCE DAILY Biologists expand on more than 150 years of textbook wisdom with a new explanation for wasp mimicry. 2 days
More virus infection, please
SCIENCE DAILY Scientists have generated a new plasmid-based reverse genetics system for rotaviruses. 2 days
Newly discovered gene variants increase risk of anxiety disorders
NEWS MEDICAL Several newly discovered variants of a gene increase the risk of developing anxiety disorders. A research team aims to derive new therapies from this finding which are better tailored to... 2 days
Structure of unique amyloid fibrils could lead to discovery of new antibiotics
NEWS MEDICAL The highly pathogenic Staphylococcus aureus bacteria is one of the five most common causes of hospital-acquired infections. In the US alone, approximately 500,000 patients... 2 days
Alzheimer's disease: Molecular study clarifies potential link to high blood sugar
MNT Sugar can damage cell proteins via glycation. Now, study finds glycation damage in enzyme for immune function and insulin regulation in early Alzheimer's. 2 days
New risk factors for anxiety disorders
SCIENCE DAILY Several newly discovered variants of a gene increase the risk of developing anxiety disorders. A research team aims to derive new therapies from this finding which are better tailored to the individual patients. 2 days
Medical News Today: Alzheimer's disease: Molecular study clarifies potential link to high blood sugar
MNT Sugar can damage cell proteins via glycation. Now, study finds glycation damage in enzyme for immune function and insulin regulation... 2 days
How proteins reshape cell membranes
PHYS.ORG Small "bubbles" frequently form on membranes of cells and are taken up into their interior. The process involves EHD proteins - a focus of research by Prof. Oliver Daumke of the MDC. He and his team have now... 2 days
Biologists expand on more than 150 years of textbook wisdom with a new explanation for wasp mimicry
PHYS.ORG The masquerade is almost perfect. Certain moths of the subfamily Arctiinae are marked with... 2 days
New algorithm identifies gene transfers between different bacterial species
PHYS.ORG Gene transfers are particularly common in the antibiotic-resistance genes of Streptococcus pneumoniae bacteria. 2 days
Scientists generate a new plasmid-based reverse genetics system for rotaviruses
PHYS.ORG Rotaviruses are the most common cause of severe diarrhea and kill hundreds of thousands of infants a year. Although current vaccines are effective in preventing aggravation of rotaviruses,... 2 days
Researchers examine the deliberate switching of individual photochromic molecules
PHYS.ORG Scientists in Bayreuth examine the deliberate switching of individual photochromic molecules. Their findings are opening up new research possibilities for visualizing the structures of complex molecules and even entire biological... 2 days
Size matters... and structure too: New tool predicts the interaction of proteins with long non-coding RNAs
PHYS.ORG Far from just reading the information contained in the human genome, and in order to fully... 2 days
Feast and famine diet may restore insulin production in diabetes
NEWS MEDICAL A landmark study conducted by the University of Southern California and published this week in the journal Cell provides hope for restoring insulin production in patients with diabetes.... 3 days
Tiny mutation makes plants less resistant to stressful conditions
PHYS.ORG Scientists from The University of Western Australia have identified a tiny mutation in plants that can influence how well a plant recovers from stressful conditions, and ultimately impact a plant's... 3 days
Improving DNA-detecting transistors
PHYS.ORG Graphene-based transistors could soon help diagnose genetic diseases. Researchers in India and Japan have developed an improved method for using graphene-based transistors to detect disease-causing genes. 3 days
Discovery of dual role played by PGK1 enzyme may indicate new therapeutic target for brain cancer
NEWS MEDICAL Discovery of a dual role played by the enzyme phosphoglycerate kinase 1 (PGK1) may indicate a new therapeutic... 3 days
Novel amyloid structure could lead to new types of antibiotics
PHYS.ORG The highly pathogenic Staphylococcus aureus bacteria is one of the five most common causes of hospital-acquired infections. In the US alone, approximately 500,000 patients at hospitals contract a... 3 days
Polymer additive could revolutionize plastics recycling
PHYS.ORG When Geoffrey Coates, the Tisch University Professor of Chemistry and Chemical Biology, gives a talk about plastics and recycling, he usually opens with this question: What percentage of the 78 million tons of plastic used annually... 3 days
Electrons use DNA like a wire for signaling DNA replication
PHYS.ORG In the early 1990s, Jacqueline Barton, the John G. Kirkwood and Arthur A. Noyes Professor of Chemistry at Caltech, discovered an unexpected property of DNA—that it can act... 3 days
Microbes in Glittering Crystal Cave Revived After 10,000 Years
LIVE SCIENCE The organisms were found inside enormous selenite crystals in a cave in Chihuahua, Mexico. They may be up to 50,000 years old. 3 days
In Photos: Shimmering Cave of the Crystals
LIVE SCIENCE Scientists have discovered and revived microbes that may have been dormant for 10,000 to 50,000 years. They discovered the microbes in the Cave of the Crystals in Mexico. 3 days
Study shows how old blood stem cells can be rejuvenated
NEWS MEDICAL When we are young, our blood stem cells produce an even and well-balanced number of red and white blood cells according to need. As we age, however, the... 3 days
A new methodology quickly reveals metabolic fluxes in cells
PHYS.ORG Although photographs of the underground stations in Barcelona would reveal the number of people waiting, when rush hour takes place, and offer clues about why some stations are busier than... 3 days
Medical News Today: Gene mutations in brain linked to OCD-like behavior
MNT Researchers found that eliminating a set of genes in the corticostriatal brain region of mice - also present in humans - led to OCD-like behavior. 3 days
New discovery is a step towards developing Huntington's disease treatments before symptoms appear
MNT Early warning signs of Huntington's disease have been uncovered in a sheep carrying the human HD mutation, leading the way for new... 3 days
Gene mutations in brain linked to OCD-like behavior
MNT Researchers found that eliminating a set of genes in the corticostriatal brain region of mice - also present in humans - led to OCD-like behavior. 3 days
Computational software that evaluates DNA samples may help in diagnosis, treatment of cancer
NEWS MEDICAL A research team from the United States and Canada has developed and successfully tested new computational software that determines whether a human... 3 days
US braces for long battle over genetic patent rights
PHYS.ORG The first skirmish was fought last week in what could be a long war over a revolutionary patent on gene-editing technology, with colossal amounts of money at stake. 3 days
Researchers reveal biological pathways involved in diabetic kidney disease
NEWS MEDICAL Diabetes is a leading cause of kidney disease, a serious, often fatal complication that is difficult to diagnose in early, potentially treatable stages. 3 days
Study reveals promising therapeutic approach that can be beneficial for older melanoma patients
NEWS MEDICAL Scientists at The Wistar Institute have shown that an anti-diabetic drug can inhibit the growth of melanoma in older patients by activating... 3 days
Europeans Brought New, Deadly Ulcer Bacteria to Americas
LIVE SCIENCE Europeans and their African slaves brought strains of ulcer- and cancer-causing H. pylori bacteria that wiped out the local strains of these bacteria and may have led to the current high rates... 3 days
Study uncovers how effects of HSP90 protein can alter course of genetic diseases
NEWS MEDICAL Proteins do most of the work inside the human body, supporting the structure, function, regulation, and repair of organs, tissues and cells. 3 days
Scientists establish ‘tipping point’ molecular link between blood sugar and Alzheimer's disease
NEWS MEDICAL For the first time a "tipping point" molecular link between the blood sugar glucose and Alzheimer's disease has been established by scientists, who have... 3 days
BUSM researchers uncover unique patterns of protein synthesis linked to increased longevity
NEWS MEDICAL Aging is a complex process that involves multiple metabolic and regulatory pathways. Previous studies have identified hundreds of genes whose deletion can significantly increase... 3 days
Researchers develop new tool that quickly reveals metabolic fluxes in cells
NEWS MEDICAL If we were to take photographs at the underground stations in Barcelona, we would see the number of people waiting, find out what time the rush... 3 days
Center for Environmental Health Sciences selects 2017 poster winners
MIT Annual poster session showcases recent work on biological effects of exposure to environmental agents. 3 days
Lack of methyl groups in gene body may lead to emergence of cancer
NEWS MEDICAL Every cell in our body contains the complete DNA library. So-called methyl groups regulate that in body tissues only the genetic information... 3 days
Researchers find new evidence to support structure-based classification system for viruses
NEWS MEDICAL Professor Robert Sinclair at the Okinawa Institute of Science and Technology Graduate University and Professor Dennis Bamford and Dr. Janne Ravantti from the University of Helsinki... 3 days
New compounds with potent anticancer activity could lessen side effects of oncological treatments
NEWS MEDICAL The Universitat Jaume I, the Spanish Centre for Advanced Scientific Research and the University of Pavia have patented new compounds with potent... 3 days
NIST patents first DNA method to authenticate mouse cell lines
PHYS.ORG "A case of mistaken identity" may drive the plot of the latest spy film or crime novel, but it's only a tale of trouble for geneticists, oncologists, drug... 3 days
New gene for atrazine resistance identified in waterhemp
PHYS.ORG Waterhemp has been locked in an arms race with farmers for decades. Nearly every time farmers attack the weed with a new herbicide, waterhemp becomes resistant to it, reducing or eliminating the... 3 days
Center for Environmental Health Sciences select 2017 poster winners
MIT Annual poster session showcases recent work on biological effects of exposure to environmental agents. 3 days
'Mission Control: The Unsung Heroes of Apollo' - Trailer Features NASA Legends
SPACE.COM NASA veterans Gene Cranz, Gene Cernan and more star in the documentary about mission control in the time of Apollo. 3 days
Researchers develop model for studying rare polio-like illness
SCIENCE DAILY Scientists have developed the first animal model for studying paralysis caused by virus linked to a polio-like illness that paralyzed 120 children in 2014. 3 days
Contact tracing and targeted insecticide spraying can curb dengue outbreaks
SCIENCE DAILY Contact tracing -- a process of identifying everyone who has come into contact with those infected by a particular disease -- combined with targeted, indoor spraying of insecticide... 3 days
Gene mutations cause leukemia, but which ones?
SCIENCE DAILY New research sought to better understand one 'typo' in a standard leukemia assay, or test. The study, however, encountered a new problem: an issue with the model system itself. 3 days
New link found between sex and viruses
SCIENCE DAILY Sexual reproduction and viral infections both rely on a functionally identical protein, according to new research. The protein enables the fusion of two cells, such as a sperm cell and egg cell, or the... 3 days
[This Week in Science] Faulty blood cells and heart disease
Science Magazine Author: Paula A. Kiberstis 3 days
[Research Article] The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport
Science Magazine DNA charge transport chemistry offers a means of long-range, rapid redox signaling.... 3 days
[Report] Optical control of cell signaling by single-chain photoswitchable kinases
Science Magazine Protein kinases transduce signals to regulate a wide array of cellular functions in eukaryotes. A generalizable method for optical control of kinases would enable fine spatiotemporal interrogation or... 3 days
[Editors' Choice] DNA methylation curbs mast cell response
Science Magazine Author: Priscilla Kelly 3 days
[This Week in Science] Defining the tree rings of T cells
Science Magazine Author: Anand Balasubramani 3 days
[Perspective] Why tolerance invites resistance
Science Magazine Bacteria use two strategies to avoid being killed by antibiotics: resistance and tolerance. Resistance mechanisms such as destruction of a drug or modification of its target allow bacteria to grow in the presence of antibiotics. Tolerance is a... 3 days
[This Week in Science] DNA charged with regulating replication
Science Magazine Authors: Guy Riddihough, Jake Yeston 3 days
[Perspective] Hematopoietic stem cells gone rogue
Science Magazine Cardiovascular disease is considered to be an aging-related disease and is the leading cause of death in the elderly in developed countries (1). As of 2013, 65% of deaths attributed to cardiovascular disease occurred among patients... 3 days
[Research Article] Cell-wide analysis of protein thermal unfolding reveals determinants of thermostability
Science Magazine Temperature-induced cell death is thought to be due to protein denaturation, but the determinants of thermal sensitivity of proteomes remain largely uncharacterized. We developed... 3 days
[This Week in Science] Shining a light on cell signaling
Science Magazine Author: Valda Vinson 3 days
[Report] The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril
Science Magazine Amyloids are ordered protein aggregates, found in all kingdoms of life, and are involved in aggregation diseases as well as in physiological activities. In microbes, functional... 3 days
[RNA Design] An old motif with new specificity
Science Magazine RNA aptamers bind to small molecules and, in the context of adjacent regulatory domains, can control cellular processes. Synthetic RNA aptamers can be selected against a target, but – [Read More] 3 days
[Mast Cells] DNA methylation curbs mast cell response
Science Magazine Mast cells are white blood cells that are perhaps best known for their role in allergic responses and asthma. Leoni et al. now show that the enzyme DNMT3A limits mast cell –... 3 days
[Development] Polarity reversal during tissue remodeling
Science Magazine The epithelial-mesenchymal transition occurs when epithelial cells lose apicobasal polarity and cell-cell contacts and migrate into surrounding tissues as mesenchymal cells. Migration – [Read More] 3 days
[Protein Design] Shining a light on cell signaling
Science Magazine Protein kinases are proteins that are used to transmit signals within cells. Zhou et al. engineered diverse kinases so that they could be switched on and off with visible light. – [Read... 3 days
[Microbiome] Bacterial battles on your skin
Science Magazine Normal human skin is colonized by a variety of normally harmless bacteria. However, one such bacterium, Staphylococcus aureus, can aggravate symptoms of atopic dermatitis. – [Read More] 3 days
[Antibiotic Resistance] Resistance on a background of tolerance
Science Magazine Bacteria survive antibiotic exposure either because they are quiescent when antibiotics are around in the highest concentrations (i.e., tolerance) or because they acquire active biochemical – [Read More] 3 days
[Immunogenomics] Defining the tree rings of T cells
Science Magazine T cell function declines with age. What does T cell aging look like at the molecular level? To understand the transcriptional programs that regulate T cell differentiation and aging, – [Read More] 3 days
[Toxic Amyloids] What's in a fold?
Science Magazine Bacterially secreted peptides known as PSMs (phenolsoluble modulins) stimulate inflammatory responses, lyse human cells, and contribute to biofilm structuring. PSMα3 is a virulent – [Read More] 3 days
[DNA Charge Transport] DNA charged with regulating replication
Science Magazine DNA can transport electrical charge over long distances and has the potential to act as a signaling system. The iron-sulfur complex [4Fe4S] found in some proteins is known to be involved –... 3 days
[DNA Replication] Diverse molecular choreography of replication
Science Magazine Accurate duplication and transmission of genetic information to the next generation requires complex molecular assemblies. Bleichert et al. review replication initiation across – [Read More] 3 days
[Vascular Disease] Faulty blood cells and heart disease
Science Magazine Recent studies have shown that elderly people's blood cells often harbor mutations in genes encoding certain epigenetic regulators. These mutations can lead to clonal expansion of the – [Read More] 3 days
Barcode scanner microscope films neurons firing
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