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Nicotine normalizes genetically-induced brain impairments linked to schizophrenia
NEWS MEDICAL A steady stream of nicotine normalizes genetically-induced impairments in brain activity associated with schizophrenia, according to new research involving the University of Colorado Boulder. 3 hours
Scientists create first stable semisynthetic organism
PHYS.ORG Life's genetic code has only ever contained four natural bases. These bases pair up to form two "base pairs"—the rungs of the DNA ladder—and they have simply been rearranged to create bacteria and butterflies, penguins and... 13 hours
New steps in the meiosis chromosome dance
PHYS.ORG Where would we be without meiosis and recombination? For a start, none of us sexually reproducing organisms would be here, because that's how sperm and eggs are made. And when meiosis doesn't work properly,... 13 hours
Researchers discover mutation hotspots that act like backseat drivers for breast cancer development
NEWS MEDICAL Researchers at the Wellcome Trust Sanger Institute have discovered 'hotspots' of mutations in breast cancer genomes, where mutations thought to be inactive... 13 hours
Serum microRNAs could serve as promising biomarkers for monitoring progression of MS
NEWS MEDICAL MicroRNAs are small RNA molecules that influence basic cellular processes and have been proposed as biomarkers for the diagnosis, progression and treatment of multiple... 13 hours
Fetal genomic sequencing could enhance detection rate of genetic findings, study shows
NEWS MEDICAL In a study to be presented Thursday, Jan. 26, in the oral plenary session at 8 a.m. PST, at the Society for Maternal-Fetal Medicine's... 14 hours
Online media use shows strong genetic influence
SCIENCE DAILY Online media use such as social networking and gaming could be strongly influenced by our genes, according to a new study. 14 hours
A gene's journey from covert to celebrated
SCIENCE DAILY Unmasking a previously misunderstood gene, scientists discover an unlikely potential drug target for gastrointestinal cancers. 14 hours
Study looks at use of evolutionary triangulation to refine results from genetic studies of preterm birth
NEWS MEDICAL In a study to be presented Thursday, Jan. 26, in the oral concurrent session at 1:15... 15 hours
New treatment recommendations for a high-risk pediatric leukemia
SCIENCE DAILY Medical researchers have identified genetic alterations that can be used to guide treatment of pediatric acute megakaryoblastic leukemia, which has a dismal prognosis. 16 hours
Medical News Today: Ultrasound may enhance delivery of RNA molecules to treat GI disorders
MNT A new study shows that ultrasound enhances delivery of RNA strands into the colon cells of mice with colitis to... 19 hours
Ultrasound may enhance delivery of RNA molecules to treat GI disorders
MNT A new study shows that ultrasound enhances delivery of RNA strands into the colon cells of mice with colitis to block production of inflammatory protein. 19 hours
Network of molecular interactions in brain cells infected by Zika virus reveals new therapeutic targets
SCIENCE DAILY Zika virus interferes with the cellular machinery controlling cell division and alters the expression of hundreds of genes... 19 hours
Conserved role for ovo protein in reproductive cell development in mice and fruit flies
SCIENCE DAILY Germline cells are the only cells that develop into eggs or sperm, while somatic cells develop into the body. Progenitors... 19 hours
Preterm birth risk: New method for filtering results from genetic studies
SCIENCE DAILY Researchers have verified genetic results from one large study of women with spontaneous preterm birth, and highlighted 13 key genes in both mothers and babies which... 19 hours
Use of fetal genetic sequencing increases the detection rate of genetic findings
SCIENCE DAILY Researchers have found that, in preliminary data, fetal genomic (whole exome) sequencing (WES) as a diagnostic test for women with pregnancies complicated by major... 20 hours
Shape-shifting nucleosomes open new avenues for epigenetics research
PHYS.ORG The textbook description of chromatin, the condensed form DNA takes when it is not in use, consists of rigid building-blocks called nucleosomes, which act as spindles on which inactive DNA can be... 23 hours
Conserved role for Ovo protein in reproductive cell development in mice and fruit flies
PHYS.ORG Germline cells are the only cells that develop into eggs or sperm, while somatic cells develop into the body. Progenitors... 24 hours
Medical News Today: Estrogen regulates the brain's fear response, protecting against PTSD
MNT A new study examines how the sex hormone estrogen affects gene regulation in the brain, affecting the formation of fear memories and PTSD. 2 days
Estrogen regulates the brain's fear response, protecting against PTSD
MNT A new study examines how the sex hormone estrogen affects gene regulation in the brain, affecting the formation of fear memories and PTSD. 2 days
New genetic engineering technique could help design, study biological systems
SCIENCE DAILY A new technique will help biologists tinker with genes, whether the goal is to turn cells into tiny factories churning out medicines, modify crops to grow with limited... 3 days
ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis
Science Magazine ASXL1 is frequently mutated in a spectrum of myeloid malignancies with poor prognosis. Loss of Asxl1... 3 days
Physical determinants of bipolar mitotic spindle assembly and stability in fission yeast
Science Magazine Mitotic spindles use an elegant bipolar architecture to segregate duplicated chromosomes with high fidelity. Bipolar spindles form from a monopolar initial condition; this is... 3 days
Visible/near-infrared subdiffraction imaging reveals the stochastic nature of DNA walkers
Science Magazine DNA walkers are designed with the structural specificity and functional diversity of oligonucleotides to actively convert chemical energy into mechanical translocation. Compared to natural protein motors, DNA walkers’... 3 days
Blood test can predict life or death outcome for patients with Ebola virus disease
SCIENCE DAILY Scientists have identified a 'molecular barcode' in the blood of patients with Ebola that can predict whether they are likely... 4 days
Jumbled chromosomes may dampen the immune response to tumors
SCIENCE DAILY How well a tumor responds to immunotherapy may depend in part on whether its chromosomes are intact or in a state of disarray, a new study reports. The finding could... 4 days
Team uncovers cellular responses to bird flu vaccine
SCIENCE DAILY New research eavesdrops on gene expression in human immune system cells before and after vaccination against bird flu, exposing cellular responses associated with a vaccine constituent called AS03, short for adjuvant system... 4 days
Cell fate regulation by LIN41 determined by binding location
PHYS.ORG Helge Großhans and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) have elucidated the mode of action of the RNA-binding protein and stem cell factor LIN41. In... 4 days
Trump asks NIH Director Francis Collins to stay on
Science Magazine Long-serving geneticist to stay in position for the time being 4 days
New hope for the future of chocolate
PHYS.ORG In an article published in PLOS ONE, Brazilian scientists detail the genetic structure and molecular diversity of the varieties of cocoa grown in the state of Bahia for over 200 years, and identify trees... 4 days
Precision medicine advances diagnosis and treatment of children with brain tumors
NEWS MEDICAL Precision medicine - in which diagnosis and treatments are keyed to the genetic susceptibilities of individual cancers - has advanced to the point where it can... 4 days
New genetic engineering technique could help design, study biological systems
PHYS.ORG A new technique will help biologists tinker with genes, whether the goal is to turn cells into tiny factories churning out medicines, modify crops to grow with limited... 4 days
NYU Langone scientists discover mechanism behind many disease-related genetic deletions
NEWS MEDICAL Scientists at NYU Langone Medical Center have discovered the mechanisms behind a genetic change known to cause a set of related diseases. 4 days
Service to screen for DNA damaging compounds released by Merck
NEWS MEDICAL Merck, a leading science and technology company, has introduced CAN MultiFlow™ screening services to more accurately predict genotoxic and mode of action* properties of substances, ingredients and drug... 4 days
RNA hitches a ride on ultrasound waves
MIT Technique enables rapid delivery of RNA to treat colon inflammation. 4 days
Popularity of non-invasive prenatal testing increasing among pregnant women
NEWS MEDICAL Genetic counselors are playing a greater role in areas of medicine in the wake of advancement in genomic technology. 4 days
New research exposes cellular responses linked to bird flu vaccine
NEWS MEDICAL New research from Vanderbilt eavesdrops on gene expression in human immune system cells before and after vaccination against bird flu. 4 days
Mayo Clinic researchers identify genetic promoter that drives lung cancer formation
NEWS MEDICAL Researchers at Mayo Clinic have identified a genetic promoter of cancer that drives a major form of lung cancer. 4 days
Study provides link between common mutations in blood cells of older adults and atherosclerosis
NEWS MEDICAL A new study provides some of the first links between relatively common mutations in the blood cells of elderly humans... 4 days
are there more than five basic tastes Are There More Than Five Basic Tastes?
NPR VIDEO Scientists have long believed we have just five tastes - salty, sweet, bitter, sour and umami (or savory). Geneticist Nicole Garneau argues we might be able to taste a sixth — fat. 4 days
Breaking: Trump asks NIH Director Francis Collins to stay on
Science Magazine Long-serving geneticist to stay in position for time being 5 days
Gene that enables memories, sense of direction produces schizophrenia-like symptoms when mutated
SCIENCE DAILY Mutations in a gene that should enable memories and a sense of direction instead can result in imprecise communication between neurons that contributes to... 5 days
Podcast: Explaining menopause in killer whales, triggering killer mice, and the role of chromosome number in cancer immunotherapy
Science Magazine This week, we chat about a surprising reason why killer whales undergo... 5 days
Mitochondrial DNA shows past climate change effects on gulls
SCIENCE DAILY To understand the present and future, we have to start with the past. A new study uses the mitochondrial DNA of Heermann's gulls to draw conclusions about how their population... 5 days
[Hematopoiesis] DNA methylation in hematopoietic cascade
Science Magazine DNA methylation is well known for its role in repressing gene expression. However, analyzing patterns of this modification across the genome of pools of cells now reveals features of – [Read More] 5 days
[Cancer] Chromosomal chaos and tumor immunity
Science Magazine Cancer immunotherapy produces durable clinical responses in only a subset of patients. Identification of tumor characteristics that correlate with responses could lead to predictive – [Read More] 5 days
[Chromatin] Deformation powers the nucleosome slide
Science Magazine In eukaryotes, DNA is packed onto nucleosomes. For transcription factors and other proteins to gain access to DNA, nucleosomes must be moved out of the way, or “remodeled”—but not d – [Read More] 5 days
[Research Article] Distortion of histone octamer core promotes nucleosome mobilization by a chromatin remodeler
Science Magazine Adenosine 5′-triphosphate (ATP)–dependent chromatin remodeling enzymes play essential biological roles by mobilizing nucleosomal DNA. Yet, how DNA is mobilized despite... 5 days
[This Week in Science] Chromosomal chaos and tumor immunity
Science Magazine Author: Paula A. Kiberstis 5 days
[Perspective] Unlocking the nucleosome
Science Magazine Almost all eukaryotic genomes are packaged as nucleosomal building blocks that are assembled from an octameric core of histone proteins around which nearly two turns of DNA are wrapped. The apparent homogeneity and stability of nucleosomes has led to their... 5 days
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Are There More Than Five Basic Tastes?
NPR
DNA duplicator small enough to hold in your hand
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For viral predators of bacteria, sensitivity can be contagious
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