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New model of genetically engineered immune cells may help fight solid tumors
NEWS MEDICAL Scientists at Memorial Sloan Kettering Cancer Center announced that they have built a new model of genetically engineered immune cells in mice that may... 51 minutes
Researchers move closer to finding potential soft spot in drug-resistant tuberculosis
NEWS MEDICAL Antibiotic-resistant tuberculosis is a public health threat. TB and other bacteria become resistant to antibiotics by evolving genetic changes over time, which they can do quite... 4 hours
“Zombie gene” protects elephants from cancer finds study
NEWS MEDICAL A new study has found that elephants do not get cancers as frequently as other animals because of a special gene that they carry. 7 hours
New 'zombie' gene found in elephants could help humans fight cancer
ABC NEWS They may not be the fastest or the smartest or even the scariest, but when it comes to beating cancer, elephants are the superheroes of the... 11 hours
Zombie gene protects against cancer -- in elephants
SCIENCE DAILY LIF6, a dead gene that came back to life, prevents cancer by killing cells with DNA damage. 13 hours
Magnetic gene in fish may someday help those with epilepsy, Parkinson's
PHYS.ORG VIDEO An aquarium fish that senses the Earth's magnetic field as it swims could help unlock how the human brain works and how diseases such as Parkinson's... 14 hours
Endangered eel larvae make a tasty treat for fish in an ocean desert
Science Magazine DNA studies point to possible contribution to European delicacy’s decline 15 hours
Inching closer to a soft spot in isoniazid-resistant tuberculosis
SCIENCE DAILY Researchers comparing clonal strains of the mycobacteria that cause TB, before and after they developed resistance to a first-line drug, found that a single genetic change may not always have... 15 hours
Magnetic gene in fish may someday help those with epilepsy, Parkinson's
SCIENCE DAILY An aquarium fish that senses the Earth's magnetic field as it swims could help unlock how the human brain works and how diseases such as Parkinson's... 15 hours
Scientists propose a new lead for Alzheimer's research
SCIENCE DAILY Scientists have suggested a potential link between iron in our cells and the rare gene mutations that cause Alzheimer's disease, which could provide new avenues for future research. 15 hours
Scientists reveal role of 'junk DNA' in cancer dissemination
NEWS MEDICAL The more scientists explore so-called "junk" DNA, the less the label seems to fit. 15 hours
'Zombie' gene protects elephants from cancer, study finds
NEWS MEDICAL An estimated 17 percent of humans worldwide die from cancer, but less than five percent of captive elephants-;who also live for about 70 years, and have about 100 times as many potentially... 16 hours
Magnetic gene in aquarium fish could open doors to treatment for epilepsy, Parkinson's
NEWS MEDICAL An aquarium fish that senses the Earth's magnetic field as it swims could help unlock how the human brain works and how... 16 hours
A resurrected gene may protect elephants from cancer
SCIENCE-NEWS Researchers have found another gene that may play a role in explaining elephants’ cancer resistance. 16 hours
Study identifies potential guidance to treat gastric cancer patients
NEWS MEDICAL Researchers from Wake Forest Baptist Medical Center and Tianjin Medical University Cancer Institute and Hospital have discovered that gastric cancer tissue samples bearing mutation of a specific gene, MUC16, too... 16 hours
Potential guidance for gastric cancer treatment
SCIENCE DAILY Researchers have discovered that gastric cancer tissue samples bearing mutation of a specific gene, MUC16, too are associated with higher tumor mutation loads. Also known as tumor mutation burdens, measurement of high genetic mutation rates among... 17 hours
Distinct origin of ADHD identified In children with history of traumatic brain injury
NEWS MEDICAL According to a study in Biological Psychiatry, physical brain injury in children contributes to the development of attention-deficit/hyperactivity disorder (ADHD), distinct from... 18 hours
Models give synthetic biologists a head start
PHYS.ORG Synthetic biologists have the tools to build complex, computer-like DNA circuits that sense or trigger activities in cells, and thanks to scientists at Rice University and the University of Houston they now they have... 18 hours
Fishing quotas upended by nuclear DNA analysis
SCIENCE DAILY Fishing quotas have been decided using an inadequate method for decades, according to a new study. The same method has also been used to decide about culling, hunting quotas, or translocating threatened species. Analyzing... 19 hours
Illinois' imperiled eastern massasauga rattlesnakes retain genetic diversity
SCIENCE DAILY A long-term study of eastern massasauga rattlesnakes in Illinois reveals that -- despite their alarming decline in numbers -- the few remaining populations have retained a surprising amount of genetic diversity. 20 hours
Elephants resist cancer by waking a zombie gene
PHYS.ORG An estimated 17 percent of humans worldwide die from cancer, but less than five percent of captive elephants—who also live for about 70 years, and have about 100 times as many potentially... 20 hours
Corymbia genome expands terpene synthesis knowledge
PHYS.ORG Genome annotations of two C. citriodora subspecies broaden understanding of the terpene synthase gene family across eucalypt lineages. 20 hours
Study identifies distinct origin of ADHD in children with history of brain injury
SCIENCE DAILY Physical brain injury in children contributes to the development of attention-deficit/hyperactivity disorder (ADHD), distinct from genetic risk for the disorder. 20 hours
For now, Illinois' imperiled eastern massasauga rattlesnakes retain their genetic diversity
PHYS.ORG Habitat loss, habitat fragmentation and the loss of genetic diversity are the three main factors driving the extinction of many wild species, and the few eastern... 20 hours
Pinpointing mutations that cause bacterial antibiotic resistance
PHYS.ORG Researchers in Japan have developed a new way of testing bacterial resistance to antibiotics, and found three previously unknown resistance mutations in the process. The fact that they detected both known and unknown mutations... 21 hours
New app, educational game gets its inspiration from phytoplankton
PHYS.ORG Marine phytoplankton are the inspiration for a new mobile application and educational game launched by University of Maine assistant professor of new media and intermedia Gene Felice. 21 hours
Researchers propose new theory for how rare gene mutations cause Alzheimer's disease
NEWS MEDICAL A University of Adelaide-led team of scientists has suggested a potential link between iron in our cells and the rare gene mutations that cause... 21 hours
The Origins of the 'OMG Particle'
LIVE SCIENCE Right now, as you read this very text, your DNA is getting sliced up by tiny, invisible bullets. 22 hours
Researchers discover new genes involved in Alzheimer’s Disease
NEWS MEDICAL Scientists have used deep gene sequencing to uncover new genetic variations involved in the development of Alzheimer’s disease. 23 hours
Scientists identify mutational signatures in ovarian cancer
NEWS MEDICAL Scientists have identified distinct patterns of genetic mutation among patients with ovarian cancer that could help them personalise treatment in the future. 23 hours
Research discoveries reveal insights behind neurological degeneration
NEWS MEDICAL Research discoveries revealing the genetic causes of neurological degeneration could be a key to slowing the progression of devastating diseases. 1 day
Study compares genetic and neural contributions to ADHD in children with or without TBI
NEWS MEDICAL According to a study in Biological Psychiatry, physical brain injury in children contributes to the development of attention-deficit/hyperactivity disorder (ADHD),... 1 day
Brown University researchers reveal key physical properties of 'giant' cancer cells
NEWS MEDICAL Polyploidal cancer cells--cells that have more than two copies of each chromosome--are much larger than most other cancer cells, are resistant to chemotherapy and radiation treatments... 1 day
New study focuses on promise of gene therapy for Amish nemaline myopathy
NEWS MEDICAL A new comprehensive natural history study about Amish nemaline myopathy in the Old Order Amish population focuses on the promise of gene therapy for... 1 day
New method provides a 'big picture' of genetic influences on traits and diseases
NEWS MEDICAL Scientists at Johns Hopkins Bloomberg School of Public Health have developed a powerful method for characterizing the broad patterns of genetic contributions... 1 day
Scarlet macaw DNA points to ancient breeding operation in Southwest
SCIENCE DAILY Somewhere in the American Southwest or northern Mexico, there are probably the ruins of a scarlet macaw breeding operation dating to between 900 and 1200 C.E., according to... 1 day
Scarlet macaw DNA points to ancient breeding operation in Southwest
PHYS.ORG Somewhere in the American Southwest or northern Mexico, there are probably the ruins of a scarlet macaw breeding operation dating to between 900 and 1200 C.E., according to... 2 days
People might have bred tropical macaws in the desert 1000 years ago
Science Magazine Ancient DNA suggests a small captive population supplied the southwestern United States with feathers and birds 2 days
What homebody island birds could tell us about adaptation and evolution
PHYS.ORG In nature, organisms are constantly adapting to their surroundings. It's why animal or plant populations with the same set of genes will do different things in... 2 days
Multi-gene test may find risk for heart disease and more
ABC NEWS New way to track millions of genetic variations promises better forecasting of people's risk for heart attacks, four other disorders 2 days
Amish nemaline myopathy natural history study finds promise for gene therapy treatment
SCIENCE DAILY A new comprehensive natural history study about Amish nemaline myopathy (ANM) in the Old Order Amish population focuses on the promise of gene therapy... 2 days
Thermal switch discovered in engineered squid-based biomaterials
SCIENCE DAILY Tuning materials for optimal optical and electrical properties is becoming commonplace. Now, researchers and manufacturers may be able to tune materials for thermal conductivity by using a squid-inspired protein made of multiple DNA repeats. 2 days
Broad 'genetic architectures' of traits and diseases
SCIENCE DAILY Scientists have developed a powerful method for characterizing the broad patterns of genetic contributions to traits and diseases. 2 days
Tiny bits of RNA can trigger pain and itchiness
SCIENCE-NEWS Two microRNAs may shed light on the causes of nerve pain and itch. 2 days
Thermal switch discovered in engineered squid-based biomaterials
PHYS.ORG Tuning materials for optimal optical and electrical properties is becoming commonplace. Now, researchers and manufacturers may be able to tune materials for thermal conductivity by using a squid-inspired protein made of multiple DNA repeats. 2 days
Disrupted nitrogen metabolism might spell cancer
SCIENCE DAILY Researchers have now shown that in many cancers, the patient's nitrogen metabolism is altered, producing detectable changes in the body fluids and contributing to the emergence of new mutations in cancerous tissue. 2 days
Long-term cannabinoid exposure impairs memory, study shows
NEWS MEDICAL A new study led by Ana Sebastião, group leader at Instituto de Medicina Molecular João Lobo Antunes and Professor of Faculdade de Medicina of Universidade de Lisboa and her team in collaboration with researchers... 2 days
Researchers predict risk for common deadly diseases from millions of genetic variants
SCIENCE DAILY A research team reports a new kind of genome analysis that could identify large fractions of the population who have a much higher risk... 2 days
Altered nitrogen metabolism may contribute to emergence of new cancer mutations
NEWS MEDICAL Nitrogen is a basic building block of all the body's proteins, RNA and DNA, so cancerous tumors are greedy for this element. Researchers at the Weizmann... 2 days
New test predicts the risk of serious disease months before symptoms appear
NEWS MEDICAL Researchers have developed a new genetic test that can identify people who are at an increased risk of serious disease, long before they develop... 2 days
Medical News Today: Leukemia: Do genes influence how people respond to therapy?
MNT Some people with acute myeloid leukemia are more responsive to chemotherapy than others. Why is this, and how can this knowledge lead to better... 2 days
Researchers explore new 'smart' approach to metabolic engineering.
PHYS.ORG Researchers in the University of Georgia College of Engineering have developed a new genetic "smart circuit" that could signal an important advance in the field of metabolic engineering. They outline their findings... 2 days
VOX pops cereal challenge
PHYS.ORG A popular technique for studying genes from different organisms plus a new carrier to transfer them to plants has yielded a powerful tool for understanding crops better. 2 days
Complex networks identify genes for biofuel crops
PHYS.ORG To improve biofuel production, scientists must understand the fundamental interactions that lead to the expression of key traits in plants and microbes. To understand these interactions, scientists are using different layers of information (about... 2 days
Genetic tools uncover cause of childhood seizure disorder missed by other methods
SCIENCE DAILY Researchers have developed high-tech tools to uncover the genetic cause of the most difficult to diagnose cases. 2 days
Researchers develop high-tech tools to uncover genetic cause of childhood seizure disorder
NEWS MEDICAL Early childhood seizures result from a rare disease that begin in the first months of life. Researchers at University of Utah Health have developed... 2 days
High-Energy Whodunit: The Origins of the 'OMG Particle'
SPACE.COM Right now, as you read this very text, your DNA is getting sliced up by tiny, invisible bullets. 2 days
Genetically modified mosquitoes and special bed nets help tackle deadly diseases
NEWS MEDICAL Researchers at the Imperial College’s South Kensington campus have successfully created genetically modified mosquitoes that would stop them from multiplying and spreading dreaded diseases such as... 2 days
FOXM1 contributes to treatment failure in acute myeloid leukemia
NEWS MEDICAL Previous research has revealed that patients with acute myeloid leukemia who also have a particular mutation in a gene called NPM1 have a higher rate of remission with chemotherapy. About... 2 days
US giant Monsanto known for controversial chemicals
PHYS.ORG From "Agent Orange" and DDT to genetically modified crops, Monsanto has long been associated with controversial chemicals, but a US court order for it to pay damages because one of its herbicides may cause... 4 days
Genetic sequencing method identifies pathogens behind respiratory illnesses in Uganda
NEWS MEDICAL A study led by researchers at Center for Infection and Immunity at Columbia University's Mailman School of Public Health and the Department of Medicine at the Columbia University... 4 days
FDA approves first targeted RNA-based treatment for rare, fatal genetic disease
NEWS MEDICAL The U.S. Food and Drug Administration today approved Onpattro (patisiran) infusion for the treatment of peripheral nerve disease (polyneuropathy) caused by hereditary transthyretin-mediated amyloidosis (hATTR) in... 4 days
Deep in the weeds: Using eDNA sequencing to survey pondweed diversity
SCIENCE DAILY Researchers have developed a protocol using environmental DNA (eDNA) to identify aquatic plant diversity, making ecological biodiversity surveys of these plant communities faster and less expensive.... 5 days
The first gene-silencing drug wins FDA approval
SCIENCE-NEWS The FDA just approved the first drug that works via RNA interference. 5 days
Laziness May Have Driven Homo Erectus to Extinction
LIVE SCIENCE It turns out laziness existed long before couches and takeout. 5 days
Coherent perfect absorption of nonlinear matter waves
Science Magazine Coherent perfect absorption is the complete extinction of incoming radiation by a complex potential in a physical system supporting wave propagation. The concept was proven for linear waves in a variety of systems including... 5 days
Generating DNA sequence data in the developing world
PHYS.ORG Globally, biodiversity is concentrated around the equator, but the scientific institutions generating DNA sequence data to study that biodiversity tend to be clustered in developed countries toward the poles. However, the rapidly... 5 days
Deep in the weeds: Using eDNA sequencing to survey pondweed diversity
PHYS.ORG Ecological surveys of biodiversity provide fundamental baseline information on species occurrence and the health of an ecosystem, but can require significant labor and taxonomic expertise to... 5 days
Laziness helped lead to extinction of Homo erectus
SCIENCE DAILY New archaeological research has found that Homo erectus, an extinct species of primitive humans, went extinct in part because they were 'lazy'. 5 days
Supercomputer simulations reveal potential therapeutic target in HIV-1 replication
NEWS MEDICAL HIV-1 replicates in ninja-like ways. The virus slips through the membrane of vital white blood cells. Inside, HIV-1 copies its genes and scavenges parts to build a protective bubble for... 5 days
Is CRISPR gene editing doomed, even as gene therapy enters the clinic?
PHYS.ORG Anyone watching the recent 60 Minutes segment on CRISPR would conclude that the gene editing technology is on the brink of pouring forth a... 5 days
Laziness led to extinction of Homo erectus
PHYS.ORG New archaeological research from The Australian National University (ANU) has found that Homo erectus, an extinct species of primitive humans, went extinct in part because they were 'lazy'. 5 days
Koala virus could provide clues to accumulated 'junk' DNA in the human genome
NEWS MEDICAL A koala virus could help researchers explain millions of years of accumulated ‘junk’ DNA in the human genome. 5 days
Methyl marks on RNA discovered to be key to brain cell connections
PHYS.ORG Methyl chemical groups dot lengths of DNA, helping to control when certain genes are accessible by a cell. In new research, UCLA scientists have... 5 days
Ability to detect RNA helps promote rapid growth, survival of fruit fly larvae
NEWS MEDICAL Fruit fly larvae can taste ribonucleosides, the building blocks of gene transcripts, according to a new study publishing on August 7 in... 5 days
OGT announces launch of updated SureSeq Interpret NGS analysis software
NEWS MEDICAL Oxford Gene Technology, The Molecular Genetics Company, has announced the launch of the eagerly-anticipated update to its SureSeq Interpret software, included with purchases of SureSeq NGS panels. 5 days
Using CRISPR-Cas9 genome editing to correct mutation responsible for sickle cell disease
NEWS MEDICAL Genome editing using the CRISPR-Cas9 system has tremendous promise for therapeutic correction of genetic errors in human cells. Prior to adoption as a medical... 5 days
New approach identifies genes that help microbes to survive in the human gut
NEWS MEDICAL Trillions of tiny microbes and bacteria live in your gut, each with their own set of genes. These gut microbes can have... 5 days
Researchers discover genetic mutation underlying debilitating childhood brain disorder
NEWS MEDICAL Ashleigh Schaffer, PhD, assistant professor of genetics at Case Western Reserve University School of Medicine, and a team of global genetics experts have discovered a genetic mutation and the faulty... 5 days
New discovery could pave way for improved leukemia treatment
NEWS MEDICAL Previous research has revealed that patients with acute myeloid leukemia who also have a particular mutation in a gene called NPM1 have a higher rate of remission with chemotherapy. About... 5 days
New technology improves CRISPR-Cas9 gene editing in mosquitoes, other species
SCIENCE DAILY A technology designed to improve CRISPR-Cas9 gene editing in mosquitoes and other arthropods succeeds with a high degree of efficiency, while eliminating the need for difficult microinjection of... 5 days
Recording every cell's history in real-time with evolving genetic barcodes
SCIENCE DAILY A new method uses evolving genetic barcodes to actively record the process of cell division in developing mice, enabling the lineage of every cell in a mouse's body... 5 days
Why do some microbes live in your gut while others don't?
SCIENCE DAILY Researchers have developed a new computational approach to identify the genes that may be important to help microbes live successfully in the human gut. 5 days
Genetic mutations of appendix cancer identified, may impact treatment
SCIENCE DAILY To understand why some patients with appendix cancer respond to standard treatment while others do not, researchers performed genetic profiling on 703 appendiceal tumors -- the largest such study of... 5 days
New technology improves CRISPR-Cas9 gene editing in mosquitoes, other species
PHYS.ORG A technology designed to improve CRISPR-Cas9 gene editing in mosquitoes and other arthropods succeeds with a high degree of efficiency, while eliminating the need for difficult microinjection of... 6 days
Why do some microbes live in your gut while others don't?
PHYS.ORG Trillions of tiny microbes and bacteria live in your gut, each with their own set of genes. These gut microbes can have both beneficial and harmful... 6 days
Why the brain system needs sleep
SCIENCE DAILY Sleep is essential for brain functionality and overall health but understanding how sleep delivers its beneficial effects remains largely unknown. Sleep researchers are exploring new and unbiased approaches that can take sleep to a systems level.... 6 days
Marine mammals lack functional gene to defend against popular pesticide
SCIENCE DAILY As marine mammals evolved to make water their primary habitat, they lost the ability to make a protein that defends humans and other land-dwelling mammals from the neurotoxic... 6 days
A conversation between plants' daily and aging clocks
SCIENCE DAILY Scientists have found out how the two clocks talk to each other genetically. Plants' circadian clock -- the 24-hour cyclic rhythm -- plays a critical role in regulating aging, in particular in... 6 days
A ghost gene leaves ocean mammals vulnerable to some pesticides
SCIENCE-NEWS Manatees, dolphins and other warm-blooded marine animals can't break down organophosphates due to genetic mutations that occurred long ago. 6 days
Developmental barcoding of whole mouse via homing CRISPR
Science Magazine In vivo barcoding using nuclease-induced mutations is a powerful approach for recording biological information, including developmental lineages; however, its application in mammalian systems has been limited. We present in vivo barcoding in... 6 days
Structure of the human PKD1/PKD2 complex
Science Magazine Mutations in two genes, pkd1 and pkd2, account for most cases of autosomal dominant polycystic kidney disease (ADPKD), one of the most common monogenetic disorders. Here we report the 3.6 Å cryo-EM structure of truncated human... 6 days
Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors
Science Magazine Messenger RNA encodes cellular function and phenotype. In the context of human cancer, it defines the identities of malignant cells and the diversity of... 6 days
Lacteal junction zippering protects against diet-induced obesity
Science Magazine Excess dietary lipid uptake causes obesity, a major global health problem. Enterocyte-absorbed lipids are packaged into chylomicrons, which enter the bloodstream through intestinal lymphatic vessels called lacteals. Here, we show that preventing lacteal chylomicron... 6 days
Why the system needs sleep
PHYS.ORG Sleep is essential for brain functionality and overall health but understanding how sleep delivers its beneficial effects remains largely unknown. In an article publishing on August 9 in the open access journal PLOS Biology, Shanaz Diessler and Maxime... 6 days
New computational strategy reveals genes that may help microbes adapt to the gut
PHYS.ORG Microbes living in a person's gut can impact their health, but it is unclear why certain microbes colonize the gut and others... 6 days
Recording every cell's history in real-time with evolving genetic barcodes
PHYS.ORG All humans begin life as a single cell that divides repeatedly to form two, then four, then eight cells, all the way up to the ~26 billion cells... 6 days
Marine mammals lack functional gene to defend against popular pesticide
PHYS.ORG As marine mammals evolved to make water their primary habitat, they lost the ability to make a protein that defends humans and other land-dwelling mammals from the neurotoxic... 6 days
Genetic mutation underlying severe childhood brain disorder identified
SCIENCE DAILY Medical researchers have discovered a genetic mutation and the faulty development process it triggers, causing a debilitating brain-based disorder in children. 6 days
Key role found for enzymes in DNA replication and sensitivity to chemotherapeutic drugs
SCIENCE DAILY A new study shows that the TLK1 and TLK2 enzymes are critical for ensuring the copying of DNA. The research is based... 6 days
Magnetic gene in fish may someday help those with epilepsy, Parkinson's
PHYS.ORG
These docile foxes may hold some of the genetic keys to domestication
Science Magazine