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Novel 'barcode' tracking of T cells in immunotherapy patients identifies likely cancer-killers
SCIENCE DAILY A new discovery makes an important step in identifying which specific T cells within the diverse army of a person's immune system are best... 1 day
Researchers shed new light on molecular pump that ejects anticancer agents
NEWS MEDICAL Sometimes cells resist medication by spitting it back out. Cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs meant to kill them.... 2 days
Fred Hutch scientists make important step in identifying specific T cells to fight against cancer
NEWS MEDICAL A new discovery by researchers at the Fred Hutchinson Cancer Research Center in Seattle makes an important step... 2 days
Tracking the fate and origin of clinically relevant adoptively transferred CD8+ T cells in vivo
Science Magazine Adoptively transferred tumor-specific cells can mediate tumor regression in cancers refractory to conventional therapy. Autologous polyclonal tumor-specific cytotoxic... 2 days
MGH researchers discover regulators of gene expression programs in medulloblastoma
NEWS MEDICAL Massachusetts General Hospital researchers have identified a mechanism that controls the expression of genes regulating the growth of the most aggressive form of medulloblastoma, the most common pediatric... 2 days
Novel antiviral drug can protect transplant patients against CMV infections
NEWS MEDICAL In a significant advance in improving the safety of donor stem cell transplants, a major clinical trial led by researchers at Dana-Farber Cancer Institute and Brigham and Women's... 2 days
Scientists devise novel DNA vaccine approach against important cancer antigen targets
NEWS MEDICAL Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against... 2 days
New structural studies reveal workings of a molecular pump that ejects cancer drugs
SCIENCE DAILY Sometimes cells spit out things we don't want them to -- like medications. Researchers have determined the three-dimensional structure of a tiny... 2 days
New structural studies reveal workings of a molecular pump that ejects cancer drugs
PHYS.ORG Sometimes cells resist medication by spitting it back out. Cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs... 2 days
Discovery of dual role played by PGK1 enzyme may indicate new therapeutic target for brain cancer
NEWS MEDICAL Discovery of a dual role played by the enzyme phosphoglycerate kinase 1 (PGK1) may indicate a new therapeutic... 3 days
NR could potentially prevent chemotherapy-induced peripheral neuropathy in cancer patients
NEWS MEDICAL A new study in rats suggests that nicotinamide riboside (NR), a form of vitamin B3, may be useful for treating or preventing nerve pain (neuropathy) caused by chemotherapy... 3 days
Computational software that evaluates DNA samples may help in diagnosis, treatment of cancer
NEWS MEDICAL A research team from the United States and Canada has developed and successfully tested new computational software that determines whether a human... 3 days
Study reveals promising therapeutic approach that can be beneficial for older melanoma patients
NEWS MEDICAL Scientists at The Wistar Institute have shown that an anti-diabetic drug can inhibit the growth of melanoma in older patients by activating... 3 days
Europeans Brought New, Deadly Ulcer Bacteria to Americas
LIVE SCIENCE Europeans and their African slaves brought strains of ulcer- and cancer-causing H. pylori bacteria that wiped out the local strains of these bacteria and may have led to the current high rates... 3 days
Researchers identify tumour protein that may hold key pancreatic cancer survival
NEWS MEDICAL A diagnosis of pancreatic cancer is often a death sentence because current chemotherapies have little impact on the disease. 3 days
Lack of methyl groups in gene body may lead to emergence of cancer
NEWS MEDICAL Every cell in our body contains the complete DNA library. So-called methyl groups regulate that in body tissues only the genetic information... 3 days
Why is pancreatic cancer so hard to treat? Stroma provides new clues
SCIENCE DAILY Why are pancreatic tumors so resistant to treatment? One reason is that the 'wound'-like tissue that surrounds the tumors, called stroma, is so dense,... 3 days
Gene mutations cause leukemia, but which ones?
SCIENCE DAILY New research sought to better understand one 'typo' in a standard leukemia assay, or test. The study, however, encountered a new problem: an issue with the model system itself. 3 days
[Perspective] Quantifying protein (dis)order
Science Magazine Twenty-five years ago, Chothia predicted that the structural domains of all proteins can be classified into about 1000 folds (1). Later studies refined this number; however, scientists also found that some proteins or parts of proteins never assume a specific... 3 days
[Perspective] Hematopoietic stem cells gone rogue
Science Magazine Cardiovascular disease is considered to be an aging-related disease and is the leading cause of death in the elderly in developed countries (1). As of 2013, 65% of deaths attributed to cardiovascular disease occurred among patients... 3 days
Tumor protein could hold key to pancreatic cancer survival
SCIENCE DAILY A diagnosis of pancreatic cancer is often a death sentence because current chemotherapies have little impact on the disease. In a new study, researchers were able to slow down growth... 3 days
PERK protein opens line of communication between inside and outside of the cell
PHYS.ORG PERK is known to detect protein folding errors in the cell. Researchers at the Laboratory of Cell Death Research & Therapy at... 3 days
Anti-aging gene identified as a promising therapeutic target for older melanoma patients
SCIENCE DAILY An anti-diabetic drug can inhibit the growth of melanoma in older patients by activating an anti-aging gene that in turn inhibits a protein involved... 3 days
How blood can be rejuvenated
SCIENCE DAILY Our blood stem cells generate around a thousand billion new blood cells every day. But the blood stem cells’ capacity to produce blood changes as we age. This leads to older people being more susceptible to anemia, lowered... 3 days
Compounds that show potent anti-cancer activity in breast and colon tumor cell lines
SCIENCE DAILY Potential drugs have shown low toxicity in non-tumor cell lines, which could decrease side effects during chemotherapy, researchers suggest. 3 days
PI3K/mTOR inhibitors may be effective against some uterine sarcomas
SCIENCE DAILY The protein P-S6S240 may serve as an indicator of poor prognosis for patients with a hard-to-treat type of uterine sarcoma called leiomyosarcoma, and preclinical data suggest that patients whose tumors... 3 days
New clinical practice guideline addresses testing of molecular biomarkers in colorectal cancer patients
NEWS MEDICAL A new, evidenced-based clinical practice guideline on molecular biomarker testing for patients with colorectal cancer identifies opportunities for improving patient outcomes. 4 days
New tool to measure patients' muscles could help predict chemotherapy side effects
NEWS MEDICAL Chemotherapy has long been standard treatment for many cancers, but its clinical benefits can also come with well-documented side effects. Doctors say the challenge... 4 days
MSK researchers harness power of CRISPR/Cas9 to create more-potent CAR T cells
NEWS MEDICAL Researchers from Memorial Sloan Kettering Cancer Center have harnessed the power of CRISPR/Cas9 to create more-potent chimeric antigen receptor (CAR) T cells that enhance tumor rejection... 4 days
Eating up to ten portions of fruit and vegetables a day may reduce disease, early death risk
NEWS MEDICAL A fruit and vegetable intake above five-a-day shows major benefit in reducing the chance... 4 days
Study finds biochemical pathway that triggers regrowth of breast cancer stem cells after chemotherapy
NEWS MEDICAL Working with human breast cancer cells and mice, researchers at Johns Hopkins say they have identified a biochemical pathway that... 4 days
One-off bowel scope cuts cancer risk for at least 17 years
SCIENCE DAILY A one-off bowel screening test reduces the risk of developing bowel cancer by more than one third and could save thousands of lives, according to a... 4 days
[Editors' Choice] Beware! Are bacteria raising your oxidative stress?
Science Magazine Peptostreptococcus anaerobius, enriched in patients with colon cancer, induces cellular proliferation and dysplasia by toll-like receptor (TLR) 2– and TLR4-dependent increase in oxidative stress and cholesterol biosynthesis. 4 days
[Research Articles] Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2
Science Magazine Trithorax-like group complex containing... 4 days
CAR T cells more powerful when built with CRISPR, researchers find
SCIENCE DAILY Researchers have harnessed the power of CRISPR/Cas9 to create more-potent chimeric antigen receptor (CAR) T cells that enhance tumor rejection in mice. 4 days
Superfluid is now helping brain surgeons
SCIENCE DAILY A superfluid, which resembles brain tissue, makes ultrasound images easier to interpret during an operation. This will make it easier for surgeons to remove brain tumors more accurately, say researchers. 4 days
Instead of starving a cancer, researchers go after its defenses
SCIENCE-NEWS There may be ways to block tumors from adapting and outrunning the body’s defenses. 4 days
One-off bowel scope cuts cancer risk for at least 17 years
MNT A one-off bowel screening test reduces the risk of developing bowel cancer by more than one third and could save thousands of lives, according to a... 4 days
Hormonal maintenance therapy may improve survival in women with chemo-resistant rare ovarian or peritoneum cancer
SCIENCE DAILY For women with a rare subtype of epithelial ovarian or peritoneum cancer, known as low-grade serous carcinoma (LGSC),... 4 days
The never-ending story: Chemicals that outlive, and harm, us
SCIENCE DAILY Chemical manufacturers have agreed to pay $670 million in damages to people with cancer and other health harm from exposure to a recently phased-out highly fluorinated chemical. In a peer-reviewed... 4 days
Scientists identify chain reaction that shields breast cancer stem cells from chemotherapy
SCIENCE DAILY Working with human breast cancer cells and mice, researchers say they have identified a biochemical pathway that triggers the regrowth of breast cancer stem... 4 days
Drugs that target tissue stiffness could potentially prevent cancer metastasis
NEWS MEDICAL In order for cancer to spread, malignant cells must break away from a tumor and through the tough netting of extracellular matrix, or ECM, that surrounds it. To... 5 days
Study: Hormonal maintenance therapy may improve survival in women with low-grade serous carcinoma
NEWS MEDICAL For women with a rare subtype of epithelial ovarian or peritoneum cancer, known as low-grade serous carcinoma, hormone maintenance therapy may significantly... 5 days
Melanoma patients' immunotherapy response linked to diversity and makeup of gut bacteria
NEWS MEDICAL Melanoma patients' response to a major form of immunotherapy is associated with the diversity and makeup of trillions of potential allies and enemies found... 5 days
Treating multiple myeloma with rabbit virus eliminates majority of malignant cells, study shows
NEWS MEDICAL Treating multiple myeloma (MM) with myxoma virus (MYXV) eliminated a majority of malignant cells in preclinical studies, report investigators at the Medical... 5 days
Researchers identify novel gene critical to development of lung and pancreatic cancer
NEWS MEDICAL Researchers at the Center for Applied Medical Research of the University of Navarra have identified a critical gene, FOSL1, in the development of lung... 5 days
Medical News Today: Exercise is best for reducing breast cancer recurrence
MNT Patients with breast cancer can incorporate a variety of lifestyle changes to reduce the risk of breast cancer recurrence, a new review suggests. 5 days
Penn expert suggests shorter radiation treatment for men with prostate cancer
NEWS MEDICAL Men with prostate cancer can receive shorter courses of radiation therapy than what is currently considered standard, according to Justin Bekelman, MD, an associate professor of... 5 days
Gene expression patterns could help predict treatment for breast cancer, research shows
NEWS MEDICAL A Michigan State University breast cancer researcher has shown that effective treatment options can be predicted based on the way certain breast cancer genes... 5 days
Novel breast tomosynthesis technique reduces screening recall rate
SCIENCE DAILY A new digital breast tomosynthesis technique has the potential to reduce the rate at which women are called back for additional examinations without sacrificing cancer detection, according to a new study. 5 days
BRCA gene plus breast cancer history leads to preventive strike against pancreatic cancer
SCIENCE DAILY More than three decades after surviving breast cancer, Susanne Calabrette faced a second scare. In June 2016, an MRI for an unrelated... 5 days
Researchers find novel, non-invasive approach for diagnosis and prognosis of prostate cancer
NEWS MEDICAL In a new paper in Springer's Journal of Materials Science, researchers at Washington State University report a new approach for the effective capture of... 5 days
Danish research may pave way for immunological treatment of cancer
NEWS MEDICAL Researchers from Aarhus University have found an important piece of the puzzle leading towards an understanding of how our innate immune system reacts against viral infections and recognises... 5 days
Using a rabbit virus to treat multiple myeloma
SCIENCE DAILY Treating multiple myeloma (MM) with myxoma virus (MYXV) eliminated a majority of malignant cells in preclinical studies, report investigators. Furthermore, introduction of MYXV had no impact on the bone marrow compartment and... 5 days
Researcher finds safer, less-invasive method of staging endometrial cancer
SCIENCE DAILY A new study identifies sentinel-lymph-node mapping as a safer and less-invasive method of staging endometrial cancer that is equally as accurate as the more traditional lymphadenectomy. 5 days
Risk factors for B cell Non-Hodgkin Lymphoma discovered
SCIENCE DAILY Israeli and Palestinian researchers have conducted a large scale epidemiological study examining risk factors for a form of Non-Hodgkin Lymphoma in these two populations. In both groups, recreational sun exposure, black hair-dye... 5 days
The way breast cancer genes act could predict your treatment
SCIENCE DAILY Effective treatment options for breast cancer can be predicted based on the way certain breast cancer genes act or express themselves, a researcher has concluded. 5 days
Prostate cancer cells grow with malfunction of cholesterol control in cells
SCIENCE DAILY Advanced prostate cancer and high blood cholesterol have long been known to be connected, but it has been a chicken-or-egg problem. Now a team of researchers... 5 days
'Sweet spot' where tissue stiffness drives cancer's spread
SCIENCE DAILY Researchers have now found that physical forces exerted between cancer cells and the ECM are enough to drive a shape change necessary for metastasis. Those forces converge on an optimal stiffness that... 5 days
New type of immunological treatment of cancer?
SCIENCE DAILY Researchers have found an important piece of the puzzle leading towards an understanding of how our innate immune system reacts against viral infections and recognises foreign DNA, for example from dying cancer cells. The... 5 days
Expert calls for shorter radiation use in prostate cancer treatment
SCIENCE DAILY Men with prostate cancer can receive shorter courses of radiation therapy than what is currently considered standard, according to scientists. 5 days
Exercise most important lifestyle change to help reduce risk of breast cancer recurrence
SCIENCE DAILY For patients with breast cancer, physical activity and avoiding weight gain are the most important lifestyle choices that can reduce the risk... 5 days
Pitt researchers uncover genetic marker that may predict drug response in many cancer types
NEWS MEDICAL Researchers at the University of Pittsburgh School of Medicine have uncovered a novel genetic mechanism of thyroid cancer, as well... 5 days
New approach for the capture of tumor-derived exosomes from a prostate cancer cell line
PHYS.ORG In a new paper in Springer's Journal of Materials Science, researchers at Washington State University report a new approach for... 5 days
Many cancer survivors change their prescription drug use for financial reasons
SCIENCE DAILY A new analysis indicates that many cancer survivors change their prescription drug use (including skipping doses or requesting cheaper medications) for financial reasons. 6 days
A simple test to verify olive oil-related health claims
PHYS.ORG The fact that olive oil polyphenols contribute to the protection of blood lipids from oxidative stress—a physiological stress in the body that can cause DNA mutations and lead to diseases... 6 days
Cancer mortality rates vary among major Hispanic ethnic groups
NEWS MEDICAL Cancer mortality rates vary considerably within the growing Hispanic population in the United States, with significant differences among the major Hispanic ethnic groups. 6 days
Study identifies sentinel-lymph-node mapping as safe, accurate way to stage endometrial cancer
NEWS MEDICAL Emma Rossi, MD, in the UNC Department of Obstetric and Gynecology's Division of Gynecologic Oncology, has published a study in Lancet Oncology online that... 6 days
New model of cervical cancer care reduces delay between diagnosis and treatment
NEWS MEDICAL Cervical cancer is the leading cause of cancer deaths for women low- and middle-income countries, including Botswana, where 75 percent of cervical cancer patients... 6 days
Cancer cells adapt nerve cell mechanisms to fuel aggressive tumor growth and spread
NEWS MEDICAL How we think and fall in love are controlled by lightning-fast electrochemical signals across synapses, the dynamic spaces between nerve cells. Until now, nobody... 6 days
Non-elderly cancer survivors more likely to change prescription drug use for financial reasons, study finds
NEWS MEDICAL A new analysis indicates that many cancer survivors change their prescription drug use (including skipping doses or requesting... 6 days
High levels of biomarker linked to poor prognosis in African-Americans with triple-negative breast cancer
NEWS MEDICAL Having high levels of a certain biomarker is linked to poor prognosis in African-American patients with triple-negative breast cancer, while... 6 days
Yale researchers identify genetic abnormalities involved in formation of atypical meningiomas
NEWS MEDICAL More than one in three tumors that affect the central nervous system are meningiomas and most are benign. 6 days
microDimensions launches new version of high precision whole slide alignment software
NEWS MEDICAL microDimensions launches a new version of its high precision whole slide alignment software Slidematch. With the new version users can align digital whole slide images from... 6 days
RCSI research focuses on need to personalise treatment for bowel cancer patients
NEWS MEDICAL Researchers in RCSI (Royal College of Surgeons in Ireland) have conducted further in-depth research to predict how patients with bowel (colorectal) cancer will respond... 6 days
Researchers develop novel in vivo model for studying pancreatic cancer
NEWS MEDICAL Researchers at Okayama University report in the December 2016 issue of the American Journal of Cancer Research a novel in vivo model for the study of pancreatic ductal... 6 days
Metabolism drives growth, division of cancer cells
SCIENCE DAILY The metabolic state of tumor cells contributes to signals that control the proliferation of tumor cells. In the 1920s, scientists observed that tumor cells radically change their metabolism. This process was termed "Warburg Effect",... 6 days
Study shows strong long-term survival rates for patients with GIST
SCIENCE DAILY Nearly one in four patients with incurable gastrointestinal stromal tumors (GIST) treated with Gleevec will survive 10 years, a new report outlines. 6 days
Soccer star Lauren Holiday opens up about brain tumor health scare
ABC NEWS The soccer star successfully had a tumor removed one month after giving birth. 7 days
Virus inspires new way to deliver cancer drugs
PHYS.ORG Drugs disguised as viruses are providing new weapons in the battle against cancer, promising greater accuracy and fewer side effects than chemotherapy. 7 days
Researchers show how metabolism drives proliferation of tumor cells
NEWS MEDICAL The metabolic state of tumor cells contributes to signals that control the proliferation of tumor cells. Already the German biochemist and Nobel Prize laureate Otto H. Warburg observed in the... 7 days
Early diagnosis does not necessarily result in longer life, study of cancer screenings shows
NEWS MEDICAL Physicians and patients like to believe that early detection of cancer extends life, and quality of life. If a cancer... 7 days
Moon Blocks (Most of) the Sun in 'Ring of Fire' Solar Eclipse
SPACE.COM
Skywatching Webcasts: Slooh 'Ring of Fire' Solar Eclipse Show
SPACE.COM
Watch Live Now! Slooh Webcast of 'Ring of Fire' Solar Eclipse
SPACE.COM
The ancient art of kirigami is inspiring a new class of materials
PHYS.ORG
Octopus vs. Crab Showdown Ends with a Twist in Startling Video
LIVE SCIENCE
The stories of supernova 1987A, as told by Science News
SCIENCE-NEWS
The dawn of a new era for Supernova 1987a (Update)
PHYS.ORG
A Killer Spin: Table Tennis Gets 'First' Robotic Coach
LIVE SCIENCE
Jupiter is a Feast for the Eyes In New Time-Lapse Animation (Video)
SPACE.COM
Video: Project aims to eliminate 'ugly' sweet potatoes
PHYS.ORG
Watch Live Sunday! Slooh Webcast of 'Ring of Fire' Solar Eclipse
SPACE.COM
Agricultural robot may be 'game changer' for crop growers, breeders
PHYS.ORG
Bumble bees are surprisingly innovative
Science Magazine
Video: The truth about catnip
PHYS.ORG
Colossal (and Growing) Crack in Antarctic Ice Shelf Seen in New Video
LIVE SCIENCE
NASA eyes Pineapple Express soaking California
PHYS.ORG
Score! Bumblebees see how to sink ball in goal, then do it better
SCIENCE-NEWS
NASA balloon recovered a year after flight over Antarctica
PHYS.ORG
'Down Syndrome' in Chimps Seen for Only the Second Time
LIVE SCIENCE
You are living inside a massive musical instrument – and here's what it sounds like
PHYS.ORG
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